161 research outputs found

    Trauma Patient Satisfaction Survey Opens Discussion about Bias in Health Care

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    Background Patient satisfaction is an important part of quality care, and patient backgrounds can influence satisfaction with care. Since trauma disproportionately affects the underserved, this study aimed to determine the effects of race and insurance status on trauma patient satisfaction. Methods The validated Trauma Patient Satisfaction Survey (TPSS) was administered to 143 hospitalized trauma patients. ANOVA and Chi2 statistics were used to compare demographics with patient satisfaction. Qualitative data were analyzed with EZ-Text. Results Of the 143 patients surveyed, 95 (66%) were African American, 33 (23%) were Caucasian, and 15 (10%) were Latino. Sixty-one patients (43%) were uninsured. No statistically significant differences for any item were noted by race or insurance status on the TPSS. No patients perceived biased care by race, but three African American patients felt that care was different because of their insurance (2%, p=0.34). Patients who did perceive bias were less satisfied with their care (p=0.03). Conclusions In this exploratory survey of hospitalized trauma patients, we did not demonstrate a significant association between race or insurance status and patient satisfaction. Though we did not detect systemic disparities with respect to bias or satisfaction with care, patients who did perceive bias were less satisfied with their care

    Rorschach determinants of creativity

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    This psychological investigation has its origin and incentive in the keen interest aroused by Professor Austin E. Grigg in the Rorschach Test, chiefly through his course in Clinical and Projective Tests

    The ecology of congeneric resprouters and reseeders (Hypericum spp.) along fire-frequented pine savanna ecoclines

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    Resprouting and reseeding shrubs are predicted to be restricted to habitats with long and short return intervals of natural disturbances, respectively. Nonetheless, resprouters and reseeders co-occur along Gulf of Mexico coastal ecoclines where lightning-ignited fires were historically frequent. In this collection of studies, I examine fire responses, habitat associations, distribution limits, and seedling recruitment of Hypericum species along ecoclines in pine savannas of the St. Joe Bay State Buffer Preserve in Gulf County of Florida. In this area, ecoclines are characterized by topographic, soil moisture, and fire heterogeneity gradients. Hypericum microsepalum, an obligate resprouter, primarily resprouts following disturbances that remove aboveground stems. It is associated with upland, dry habitats that frequently burn, but can survive over a wide range of habitats along ecoclines. Hypericum chapmanii, an obligate reseeder, is killed by fires and recruits with a pulse of seedlings. Hypericum brachyphyllum, a facultative reseeder/resprouter, both reseeds and resprouts after low intensity disturbances, but only reseeds after high intensity disturbances. Hypericum brachyphyllum and H. chapmanii are associated with intermediate, mesic areas along ecoclines where fires become increasingly heterogeneous to rare as they move down slopes. These species have low survival outside of their original habitats. Direct effects of fire, specifically removal of aboveground biomass and litter, increase seedling recruitment of H. brachyphyllum and H. chapmanii. Fires have no direct effect on the growth of H. brachyphyllum to juvenile and reproductive adult stages, but indirectly increase growth of H. chapmanii. This is likely the result of fire facilitating regeneration of associated nurse plants. Therefore, fires are important for seedling recruitment and growth of Hypericum species. Time to reproduction is longer for H. chapmanii (3+ years) and H. brachyphyllum (3 years) than H. microsepalum (2 years). Differences in time to reproduction should cause species to segregate along a fire frequency gradient. I thus conclude that heterogeneous fires within a high fire frequency landscape may increase persistence of Hypericum resprouters and reseeders in higher and lower areas along ecoclines, respectively. It should also allow plants with different life histories to co-occur in intermediate areas along ecoclines where fires are patchy and vary in intensity

    Recurrent violent injury: magnitude, risk factors, and opportunities for intervention from a statewide analysis.

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    INTRODUCTION: Although preventing recurrent violent injury is an important component of a public health approach to interpersonal violence and a common focus of violence intervention programs, the true incidence of recurrent violent injury is unknown. Prior studies have reported recurrence rates from 0.8% to 44%, and risk factors for recurrence are not well established. METHODS: We used a statewide, all-payer database to perform a retrospective cohort study of emergency department visits for injury due to interpersonal violence in Florida, following up patients injured in 2010 for recurrence through 2012. We assessed risk factors for recurrence with multivariable logistic regression and estimated time to recurrence with the Kaplan-Meier method. We tabulated hospital charges and costs for index and recurrent visits. RESULTS: Of 53 908 patients presenting for violent injury in 2010, 11.1% had a recurrent violent injury during the study period. Trauma centers treated 31.8%, including 55.9% of severe injuries. Among recurrers, 58.9% went to a different hospital for their second injury. Low income, homelessness, Medicaid or uninsurance, and black race were associated with increased odds of recurrence. Patients with visits for mental and behavioral health and unintentional injury also had increased odds of recurrence. Index injuries accounted for 105millionincosts,andrecurrentinjuriesaccountedforanother105 million in costs, and recurrent injuries accounted for another 25.3 million. CONCLUSIONS: Recurrent violent injury is a common and costly phenomenon, and effective violence prevention programs are needed. Prevention must include the nontrauma centers where many patients seek care

    Modernizing Biomedical Training: Replacing Live Animal Laboratories with Human Simulation

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    This chapter reviews the global trend towards a modernization of biomedical education in favor of simulation-based training methods, which studies confirm improve student learning and transference of applied skills to clinical practice, reduce laboratory costs, and spare animals from harmful procedures

    Genetic Diversity, Population Structure, and Demographic History of Exploited Sea Urchin Populations (Tripneustes Gratilla) in the Philippines

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    The sea urchin Tripneustes gratilla is ecologically and economically important in the Indo-Pacific region. We use population genetic methods to investigate the population structure and historical demography of exploited populations in the Philippines. Sea urchins sampled in 6 localities in western Luzon and 4 outgroup sites were sequenced for mitochondrial cytochrome oxidase-1 gene (n = 282) and genotyped for seven microsatellite loci (n = 277). No significant genetic structure was found for either class of markers, indicating either extensive gene flow across the archipelago, or that populations have high genetic diversity and have not yet attained equilibrium between genetic drift and migration following large changes in demography. Interestingly, demographic inferences from the two types of markers were discordant. Mitochondrial lineages showed demographic expansion during the Pleistocene while microsatellite data indicated population decline. Estimates for the date of each event suggest that a Pleistocene expansion could have preceded a more recent population decline, but we also discuss other hypotheses for the discordant inferences.The high genetic diversity and broad distribution of haplotypes in populations that recently recovered from fishery collapse indicate that this species is very resilient over evolutionary timescales

    Humanitarianism 2.0

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    It is difficult to overstate the importance of trust in a world where global networks facilitate the constant flow of contradictory information. The search for verifiable leads and trusted sources is a central facet of daily communication and is becoming more so as our connections with one another become more decontextualised, geographically distant and, increasingly entirely virtual. The swell of internet connection rates across the world has meant an explosion of interaction and allowed new opportunities for global collective action. Whilst countless words have been written exploring the dangers of this global network and the threats that “new media” represents to social structures and moral fabrics, this collection seeks to explore the role that new social technologies are having in the world of humanitarianism and conflict response

    Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

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    This is the published version. Copyright 1995 American Society for Clinical Investigation.Vascular cell adhesion molecule-1 (VCAM-1), an inducible cell-cell recognition protein on the endothelial cell surface (EC), has been associated with early stages of atherosclerosis. In view of the accelerated vascular disease observed in patients with diabetes, and the enhanced expression of VCAM-1 in diabetic rabbits, we examined whether irreversible advanced glycation endproducts (AGEs), could mediate VCAM-1 expression by interacting with their endothelial cell receptor (receptor for AGE, RAGE). Exposure of cultured human ECs to AGEs induced expression of VCAM-1, increased adhesivity of the monolayer for Molt-4 cells, and was associated with increased levels of VCAM-1 transcripts. The inhibitory effect of anti-RAGE IgG, a truncated form of the receptor (soluble RAGE) or N-acetylcysteine on VCAM-1 expression indicated that AGE-RAGE-induced oxidant stress was central to VCAM-1 induction. Electrophoretic mobility shift assays on nuclear extracts from AGE-treated ECs showed induction of specific DNA binding activity for NF-kB in the VCAM-1 promoter, which was blocked by anti-RAGE IgG or N-acetylcysteine. Soluble VCAM-1 antigen was elevated in human diabetic plasma. These data are consistent with the hypothesis that AGE-RAGE interaction induces expression of VCAM-1 which can prime diabetic vasculature for enhanced interaction with circulating monocytes

    Deadly Partners: Interdependence of Alcohol and Trauma in the Clinical Setting

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    Trauma is the leading cause of death for Americans aged 1 to 45. Over a third of all fatal motor vehicle collisions and nearly eighty percent of completed suicides involve alcohol. Alcohol can be both a cause of traumatic injury as well as a confounding factor in the diagnosis and treatment of the injured patient. Fortunately, brief interventions after alcohol-related traumatic events have been shown to decrease both trauma recidivism and long-term alcohol use. This review will address the epidemiology of alcohol-related trauma, the influence of alcohol on mortality and other outcomes, and the role of prevention in alcohol-related trauma, within the confines of the clinical setting

    The EGS Grading Scale For Skin And Soft Tissue Infections Is Predictive Of Poor Outcomes : A Multicenter Validation Study

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    Introduction: Over the last five years, the American Association for the Surgery of Trauma (AAST) has developed grading scales for Emergency General Surgery (EGS) diseases. In a prior validation study using diverticulitis, the grading scales were predictive of complications and length of stay. As EGS encompasses diverse diseases, the purpose of this study was to validate the grading scale concept against a different disease process with a higher associated mortality. We hypothesized that the grading scale would be predictive of complications, length of stay and mortality in skin and soft tissue infections (STI). Methods: This multi-institutional trial encompassed 12 centers. Data collected included demographic variables, disease characteristics and outcomes such as mortality, overall complications, hospital and ICU length of stay. The EGS scale for STI was used to grade each infection and two surgeons graded each case to evaluate inter-rater reliability. Results: 1170 patients were included in this study. Inter-rater reliability was moderate (kappa coefficient 0.472-0.642, with 64-76% agreement). Higher grades (IV and V) corresponded to significantly higher LRINEC scores when compared with lower EGS grades. Patients with grade IV and V STI had significantly increased odds of all complications, as well as ICU and overall length of stay. These associations remained significant in logistic regression controlling for age, gender, comorbidities, mental status and hospital-level volume. Grade V disease was significantly associated with mortality as well. Conclusion: This validation effort demonstrates that Grade IV and V STI are significantly predictive of complications, hospital length of stay and mortality. Though predictive ability does not improve linearly with STI grade, this is consistent with the clinical disease process, in which lower grades represent cellulitis and abscess and higher grades are invasive infections. This second validation study confirms the EGS grading scale as predictive, and easily used, in disparate disease processes
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