1,450 research outputs found

    Numerical analysis of temperature stratification in the CIRCE pool facility

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    In the framework of Heavy Liquid Metal (HLM) GEN IV Nuclear reactor development, the focus is in the combination of security and performance. Numerical simulations with Computational Fluid Dynamics (CFD) or system codes are useful tools to predict the main steady-state phenomena and how transitional accidents could unfold in GEN IV reactors. In this paper, to support the validation of CFD as a valid tool for the design, the capability of ANSYS CFX v15.0 to simulate and reproduce mixed natural convection and thermal stratification phenomena inside a pool is investigated. The 3D numerical model is based on the CIRCE facility, located in C.R. ENEA Brasimone. It is a pool facility, structured with all the components necessary to simulate the behavior of an HLM reactor, where LBE flows into the primary circuit. For the analysis, the LBE physical properties are implemented in CFX by using recent NEA equations [2]. Previously published RELAP5-3D© results [1] are employed to derive accurate boundary conditions for the simulation of the steady-state conditions in the pool and for CFX validation. The analysis focuses on the pool natural circulation with the presence of thermal structures in contact with LBE, considered as constant temperature sources. The development of thermal stratification in the pool is observed and evaluated with a mesh sensitivity analysis

    Ricerca in-formazione. Tematiche trasversali e casi di studio nella ricerca dei dottorati

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    La sessione denominata Ricerca in-formazione raccoglie i contributi dei giovani ricercatori, dottori di ricerca e dottorandi. Il tavolo di lavoro ha visto la partecipazione di 16 studiosi che hanno indirizzato le proprie ricerche verso ‘tematiche cosiddette ‘trasversali’ e vari ‘casi di studio’, toccando diversificati filoni di ricerca che affrontano aspetti di natura storiografica, critica, di lettura ma anche di tutela e questioni di restauro aperto a campi sempre più ampi, come quelli dell’ambiente urbano e del paesaggio. Se si osserva più da vicino, si registra la prevalenza di contributi prettamente storici; cioè studi volti soprattutto all’approfondimento dei dati conoscitivi ed evolutivi di trasformazione delle architetture; parallelamente, coinvolgendo la cultura storica, altri contributi aprono il confronto su varie esperienze che mettono in discussione questioni di compatibilità e implicano continui aggiustamenti dottrinari vagliati in rapporto all’ampliamento del campo del restauro. Inoltre, facendo riferimento all’interdisciplinarietà dei dati, insieme ai colleghi - Fabio Mariano e Eugenio Vassallo – si è tentato di ragionare sui modi di approccio alle singole tematiche che, mostrando uno sviluppo differenziato, spaziano fra tematiche teoretiche, tecniche e progettuali

    GEN-IV LFR development: Status & perspectives

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    Since Lead-cooled Fast Reactors (LFR) have been conceptualized in the frame of Generation IV International Forum (GIF), great interest has focused on the development and testing of new technologies related to Heavy Liquid Metal (HLM) nuclear reactors. In this frame, ENEA developed one of the larger European experimental fleet of experimental facilities aiming at investigating HLM thermal-hydraulics, coolant chemistry control, corrosion behavior for structural materials, and at developing components, instrumentations and innovative systems, supported by experiments and numerical tools. The present work aims at highlighting the capabilities and competencies developed by ENEA so far in the frame of the liquid metal technologies for GEN-IV LFR. In particular, an overview on the ongoing R&D experimental program will be depicted considering the actual fleet of facilities: CIRCE, NACIE-UP, LIFUS5, LECOR and HELENA. CIRCE (CIRColazione Eutettico) is the largest HLM pool facility presently in operation worldwide. Full scale component tests, thermal stratification studies, operational and accidental transients and integral tests for the nuclear safety and SGTR (Steam Generator Tube Rupture) events in a large pool system can be studied. NACIE-UP (NAtural CIrculation Experiment-UPgraded) is a loop with a HLM primary and pressurized water secondary side and a 250 kW power Fuel Pin Simulator working in natural and mixed convection. LIFUS5 (lithium for fusion) is a separated effect facility devoted to the HLM/Water interaction. HELENA (HEavy Liquid metal Experimental loop for advanced Nuclear applications) is a pure lead loop with a mechanical pump for high flow rates experiments. LECOR (LEad CORrosion) is a corrosion loop facility with oxygen control system installed. All the experiment actually ongoing on these facilities are described in the paper, depicting their role in the context of GEN-IV LFR development

    Artificial Intelligence and digital medicine for integrated home care services in Italy: Opportunities and Limits

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    Home healthcare in the Italian health system has proven to be an essential factor in adequately responding to the health needs of an increasingly aging population. The opportunities offered by digitization and new technologies, such as artificial intelligence (AI) and robotics, are a lever for making home care services more effective and efficient on the one hand, and on the other for improving remote patient monitoring. Telemedicine devices have enormous potential for telemonitoring and telerehabilitation of patients suffering from chronic disabling diseases; in particular, AI systems can now provide very useful managerial and decision-making support in numerous clinical areas. AI combined with digitalization, could also allow for the remote monitoring of patients' health conditions. In this paper authors describe some digital and healthcare tools or system of AI, such as the Connected Care model, the Home Care Premium (HCP) project, The Resilia App and some professional service robotics. In this context, to optimize potential and concrete healthcare improvements, some limits need to be overcome: gaps in health information systems and digital tools at all levels of the Italian National Health Service, the slow dissemination of the computerized medical record, issues of digital literacy, the high cost of devices, the poor protection of data privacy. The danger of over-reliance on such systems should also be examined. Therefore the legal systems of the various countries, including Italy, should indicate clear decision-making paths for the patient

    Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription

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    TET enzymes are the epigenetic factors involved in the formation of the Sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis. In particular, TET1 acts as tumor suppressor preventing cell proliferation and tumor metastasis and it has frequently been found down-regulated in cancer. Thus, considering the importance of a tight control of TET1 expression, the epigenetic mechanisms involved in the transcriptional regulation of TET1 gene are here investigated. The involvement of poly(ADP-ribosyl)ation in the control of DNA and histone methylation on TET1 gene was examined. PARP activity is able to positively regulate TET1 expression maintaining a permissive chromatin state characterized by DNA hypomethylation of TET1 CpG island as well as high levels of H3K4 trimethylation. These epigenetic modifications were affected by PAR depletion causing TET1 downregulation and in turn reduced recruitment of TET1 protein on HOXA9 target gene. In conclusion, this work shows that PARP activity is a transcriptional regulator of TET1 gene through the control of epigenetic events and it suggests that deregulation of these mechanisms could account for TET1 repression in cancer

    Restauro e conservazione delle architetture fortificate allo stato di rudere. Il caso del Castrum Flastrae

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    The system of medieval military fortifications in the Italian territory constitutes a fundamental part of the monumental and historical heritage of our country. Of these, several, have come to the present day with the architectural consistency of the ruin and, despite their high documentary value, very often characterized by an advanced state of deterioration and neglect that calls into serious risk their preservation and survival. The Castrum Flastrae constitutes a significant synthesis of this reality and, for this reason, has been undertaken a research on this important military fortification with the hope that this work will serve as a concrete starting point for future conservation action and that can serve as driving force for raising awareness and dissemination of a fundamental theme like this for the outback Macerata’s territory and for the “Monti Sibillini National Park”

    Transient analysis of SIRIO using RELAP5/MOD3.3 system code

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    The main outcome of the present paper is the feasibility analysis of SIRIO (Sistema di rimozione della Potenza di decadimento per Reattori InnOvativi) facility with conditions based on those of its reference facility. The aim of SIRIO project is to study an innovative Decay Heat Removal System (DHRS) for liquid metal reactor and advanced Light Water Reactor (LWR). Such system must ensure passive control of the power removed from the primary system in abnormal condition, and must ensure reactor cooling in both short and long term. This study present numerical simulations developed with RELAP5/MOD3.3, of two operational procedures: the first one is a steady-state and the second one is a transient phase with decay heat generation. The thermal-hydraulic model, developed with RELAP5/MOD3.3, simulates the whole facility including lines, valves, water and gas tanks, and the Molten Salts (MS) gap. Since there is not experimental data, the present paper is a pre-test study based on SIRO facility design

    Chemical potential driven phase transition of black holes in anti-de Sitter space

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    Einstein-Maxwell theory conformally coupled to a scalar field in D dimensions may exhibit a phase transition at low temperature whose end point is an asymptotically anti-de Sitter black hole with a scalar field profile that is regular everywhere outside and on the horizon. This provides a tractable model to study the phase transition of hairy black holes in anti-de Sitter space in which the backreaction on the geometry can be solved analytically.Fil: Galante, Mariano. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; ArgentinaFil: Giribet, Gaston Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Université Libre de Bruxelles; Bélgica. Pontificia Universidad Católica de Valparaíso; ChileFil: Goya, Andrés Fabio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; ArgentinaFil: Oliva, Julio. Universidad de Concepción; Chil
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