Disruption of transitional stages in 24-h blood pressure recording in renal transplant recipients

Patients with kidney replacement exhibit disrupted circadian rhythms. Most studies measuring blood pressure use the dipper/non-dipper classification, which does not consider analysis of transitional stages between low and high blood pressure, confidence intervals nor shifts in the time of peak, while assuming subjective onsets of night and day phases. In order to better understand the nature of daily variation of blood pressure in these patients, we analyzed 24 h recordings from 41 renal transplant recipients using the non-symmetrical double-logistic fitting assessment which does not assume abruptness nor symmetry in ascending and descending stages of the blood pressure profile, and a cosine best-fitting regression method (Cosinor). Compared with matched controls, double-logistic fitting showed that the times for most transitional stages (ascending systolic and descending systolic, diastolic, and mean arterial pressure) had a wider distribution along the 24-h. The proportion of individuals without daily blood pressure rhythm in the transplanted group was larger only for systolic arterial pressure, and the amplitude showed no significant difference. Furthermore, the transplant recipient group had a less pronounced slope in descending systolic and ascending mean blood pressure. Cosinor analysis confirmed this phase-related changes, showing a wider distribution of times of peak (acrophases). We conclude that daily disruptions in renal transplant recipients can be explained not necessarily by an absence in diurnal variation, but also by changes in waveform-related parameters of the rhythm, and that alterations in the phase of the rhythm are the most consistent finding in these patients.Fil: Katz, Marcelo E.. Universidad Nacional de Quilmes; ArgentinaFil: Margulis, Fernando. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich; ArgentinaFil: Schiavelli, Rubén. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich; ArgentinaFil: Arias, Pablo. Universidad de Buenos Aires; ArgentinaFil: Head, Geoffrey A.. No especifíca;Fil: Golombek, Diego Andres. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Manejo interno de residuos biopatogénicos en un laboratorio de diagnóstico de enfermedades que afectan a las aves ubicado en la provincia de Entre Ríos

Las actividades dentro de un laboratorio de diagnostico de enfermedades que afectan a las aves tienen un riesgo potencial de infección para el personal por lo que para llevar a cabo dichas tareas se deben tomar medidas de seguridad pertinentes. Por ello, el objetivo de este trabajo es describir procedimientos técnicos y operativos del manejo interno de los RBP generados en un laboratorio de diagnóstico de enfermedades que afectan a las aves, ubicado en la provincia de Entre Ríos, respetando el marco legal vigente.EEA Concepción del UruguayFil: Margulis, Javier E. Actividad privada, Basavilbaso, Entre Ríos; ArgentinaFil: Rodriguez, Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Breton, Adrián. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Entre Rios; ArgentinaFil: Bueno, Dante Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina. Universidad Autónoma de Entre Ríos. Facultad de Ciencia y Tecnología, Sede Basavilbaso ; ArgentinaFil: Raffo, Fernando C. Universidad Tecnológica Nacional. Facultad Regional Concepción del Uruguay; Argentin

Diversification of investment amounts in a currency portfolio through GRG and Evolutionary Algorithms

Investment portfolios are collections of exchange instruments that aim to generate a maximum gain with a minimal risk, their design, usually done through a series of equations formulated by Harry Markowitz, which have as purpose to build an optimal portfolio from diversification, in other words, to assign to the assets different investment amounts. According to the specialized literature, these are usually calculated by means of a nonlinear programming method called Generalized Reduced Gradient (GRG), and also by evolutionary algorithms such as the Differential Evolution algorithm and the Genetic Algorithm in binary codings or Gray. This proposal presents the construction of an alternative investment portfolio called a currencies portfolio composed of six currencies yields regarding the Mexican peso. The amounts to be invested in each currency are formulated according to different scenarios, solved by the GRG and compared with solutions obtained by a Differential Evolution algorithm and a Genetic Algorithm, the latter demonstrated it is the best calculation option, it should be noted that the heuristic methods were coded with real numbers

Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project)

30nononenoneMari, Andrea; Campi, Riccardo; Schiavina, Riccardo; Amparore, Daniele; Antonelli, Alessandro; Artibani, Walter; Barale, Maurizio; Bertini, Roberto; Borghesi, Marco; Bove, Pierluigi; Brunocilla, Eugenio; Capitanio, Umberto; Da Pozzo, Luigi; Daja, Julian; Gontero, Paolo; Larcher, Alessandro; Li Marzi, Vincenzo; Longo, Nicola; Mirone, Vincenzo; Montanari, Emanuele; Pisano, Francesca; Porpiglia, Francesco; Simeone, Claudio; Siracusano, Salvatore; Tellini, Riccardo; Trombetta, Carlo; Volpe, Alessandro; Ficarra, Vincenzo; Carini, Marco; Minervini, Andrea*Mari, Andrea; Campi, Riccardo; Schiavina, Riccardo; Amparore, Daniele; Antonelli, Alessandro; Artibani, Walter; Barale, Maurizio; Bertini, Roberto; Borghesi, Marco; Bove, Pierluigi; Brunocilla, Eugenio; Capitanio, Umberto; Da Pozzo, Luigi; Daja, Julian; Gontero, Paolo; Larcher, Alessandro; Li Marzi, Vincenzo; Longo, Nicola; Mirone, Vincenzo; Montanari, Emanuele; Pisano, Francesca; Porpiglia, Francesco; Simeone, Claudio; Siracusano, Salvatore; Tellini, Riccardo; Trombetta, Carlo; Volpe, Alessandro; Ficarra, Vincenzo; Carini, Marco; Minervini, Andre