Elaphostrongylus spp. from Scandinavian cervidae - a scanning electron microscope study (SEM)

Nematodes of the genus Elaphostrongylus collected from moose (Alces alces L.), reindeer (Rangifer tarandus tarandus L.), and red deer (Cervus elaphus L.), respectively, were studied by means of scanning electron microscopy. Morphological differences in the ribs of the genital bursa were demonstrated. The Elaphostrongylus species from reindeer and red deer differed from each other in four ribs of the genital bursa. These results agree with the morphological characters of E. cervi and E. rangiferi described by Cameron (1931) and Mitskevitch (1960). The genital bursa of Elaphostrongylus sp. from moose, in accordance with the description of E. alces by Steen et al. (1989) showed characteristics differing from those found in Elaphostrongylus spp. from reindeer and red deer respectively. These results support the hypothesis that there are three separate species of Elaphostrongylus present in Scandinavian Cervidae. Svep-elektroniska studier på Elaphostrongylus spp. hos skandinaviska hjortdjur.Abstract in Swedish / Sammandrag: Rundmaskar inom slaktet Elaphostrongylus funna hos alg (Alces alces L.), ren (Rangifer tarandus tarandus L.) och kronhjort(Cervus elaphus L.) studerades med hjalp av svepelelektronmikroskop. De hanliga bursorna med sin a stodjeribbor uppvisade variationer i utseende, langd och placering mellan dessa rundmaskar. De arter av Elaphostrongylus funna hos ren och kronhjort skilde sig åt avseende fyra stodjeribbor på de hanliga bursorna. Dessa resultat stammer val overens med de karaktarer som tidigare ar beskrivna av Cameron(1931) och av Mitskevich (1960). Den hanliga bursan hos arten Elaphostrongylus funnen hos alg, vilken tidigare ar beskriven av Steen et al. (1989), visade upp ett utseende som skilde sig från bursorna hos de Elaphostrongylus-arter funna hos ren och kronhjort. Dessa resultat stoder hypotesen om tre skilda arter av Elaphostrongylus hos skandinaviska hjortdjur

Substituted decision making and the dispositional choice account

There are two main ways of understanding the function of surrogate decision making in a legal context: the Best Interests Standard and the Substituted Judgment Standard. First, we will argue that the Best Interests Standard is difficult to apply to unconscious patients. Application is difficult regardless of whether they have ever been conscious. Second, we will argue that if we accept the least problematic explanation of how unconscious patients can have interests, we are also obliged to accept that the Substituted Judgment Standard can be coherently applied to patients who have never been conscious at the same extent as the Best Interests Standard. We then argue that acknowledging this result is important in order to show patients respect.acceptedVersio

A long-term Arctic snow depth record from Abisko, northern Sweden, 1913–2004

A newly digitized record of snow depth from the Abisko Scientific Research Station in northern Sweden covers the period 1913-present. Mean snow depths were taken from paper records of measurements made on a profile comprising 10 permanent stakes. This long-term record yields snow depths consistent with two other shorter term Abisko records: measurements made at another 10-stake profile (1974-present) and at a single stake (1956-present). The measurement interval is variable, ranging from daily to monthly, and there are no data for about half Of the winter months in the period 1930-1956. To fill the gaps, we use a simple snowpack model driven by concurrent temperature and precipitation measurements at Abisko. Model snow depths are similar to observed; differences between the two records are comparable to those between profile and single stake measurements. For both model and observed snow depth records, the most statistically significant trend is in winter mean snow depths, amounting to an increase of about 2 cm or 5% of the mean per decade over the whole measurement period, and 10% per decade since the 1930-40s, but all seasonal means of snow depth show positive trends on the longest timescales. However, the start, end, and length of the snow season do not show any statistically significant long-term trends. Finally, the relation between the Arctic Oscillation index and Abisko temperature, precipitation and snow depth is positive and highly significant, with the best correlations for winter

Psychometric properties of the DISABKIDS Chronic Generic Module (DCGM-37) when used in children undergoing treatment for cancer

Background: The aim was to evaluate data quality and psychometric properties of an instrument for measurement of health-related quality of life: DISABKIDS Chronic Generic Module (DCGM-37) used in school-aged children with cancer. Methods: All school-children diagnosed with cancer in Sweden during a two-and-a-half year period were invited to participate in the study. Analysis was performed on combined data from two assessments, two and-a-half and five months after start of cancer treatment (n = 170). The instrument was examined with respect to feasibility, data quality, reliability and construct and criterion-based validity. Results: Missing items per dimension ranged from 0 to 5.3 percent, with a majority below three percent. Cronbach's alpha values exceeded 0.70 for all dimensions. There was support for the suggested groupings of items into dimensions for all but six of the 36 items of the DCGM-37 included in this study. The instrument discriminated satisfactorily between diagnoses reflecting treatment burden. Conclusions: The results indicate satisfactory data quality and reliability of the DCGM-37 when used in children undergoing treatment for cancer. Evaluation of construct validity showed generally acceptable results, although not entirely supporting the suggested dimensionality. Continued psychometric evaluation in a larger sample of children during and after treatment for cancer is recommended

Change in electron and spin density upon electron transfer to haem

AbstractHaems are the cofactors of cytochromes and important catalysts of biological electron transfer. They are composed of a planar porphyrin structure with iron coordinated at the centre. It is known from spectroscopy that ferric low-spin haem has one unpaired electron at the iron, and that this spin is paired as the haem receives an electron upon reduction (I. Bertini, C. Luchinat, NMR of Paramagnetic Molecules in Biological Systems, Benjamin/Cummins Publ. Co., Menlo Park, CA, 1986, pp. 165–170; H.M. Goff, in: A.B.P. Lever, H.B. Gray (Eds.), Iron Porphyrins, Part I, Addison-Wesley Publ. Co., Reading, MA, 1983, pp. 237–281; G. Palmer, in: A.B.P. Lever, H.B. Gray (Eds.), Iron Porphyrins, Part II, Addison-Wesley Publ. Co., Reading, MA, 1983, pp. 43–88). Here we show by quantum chemical calculations on a haem a model that upon reduction the spin pairing at the iron is accompanied by effective delocalisation of electrons from the iron towards the periphery of the porphyrin ring, including its substituents. The change of charge of the iron atom is only approx. 0.1 electrons, despite the unit difference in formal oxidation state. Extensive charge delocalisation on reduction is important in order for the haem to be accommodated in the low dielectric of a protein, and may have impact on the distance dependence of the rates of electron transfer. The lost individuality of the electron added to the haem on reduction is another example of the importance of quantum mechanical effects in biological systems

The relationship between exercise induced bronchial obstruction and health related quality of life in female and male adolescents from a general population

Background: Previous studies have observed that exercise-induced bronchoconstriction (EIB) is more common and more strongly related to exercise related breathing problems in female adolescents than male adolescents. However, few studies have investigated the association between EIB and health related quality of life (HRQoL) from a gender perspective. The aim of this study was to examine the association between EIB and HRQoL and physical activity level in female and male adolescents with and without EIB. Methods: From a population based study on exercise-induced breathing problems among adolescents (13-15 years, n = 3838) a cross sectional study with prospective data collection was carried out in a random subsample of 140 adolescents. The subjects in the sample were tested for EIB with a standardised exercise test, of which 49 adolescents were tested positive. HRQoL was assessed with the Pediatric Quality of Life Inventory (PedsQL) and the adolescents' physical activity levels were measured objectively with accelerometer. Results: The female subjects with EIB reported a lower HRQoL, both in total score (p = 0.03) and physical functioning score (p = 0.009) and had a lower baseline FEV1 compared to females without EIB (88 vs. 94 % predicted, p = 0.001). No differences were found in HRQoL or baseline lung function between males with or without EIB. There were no differences in minutes of moderate to vigorous physical activity per day between females or males with and without EIB. Conclusion: In a general population, the female adolescents with EIB had lower HRQoL and poorer baseline lung function compared to counterparts without EIB. These differences were not observed in males. EIB does not appear to affect the level of daily physical activity neither in females nor males

Определение приведенного модуля объемной упругости участка напорной магистрали гидропривода

Syftet med denna undersökning är att undersöka om korta moment inspirerade av problembaserat lärande under uppstarten av en längre kurs på högskolenivå kan förbättra förutsättningarna för lärande, inom det naturvetenskapliga ämnet och designämnet. För att undersöka frågeställningen genomfördes en enkätundersökning med studenter på Textilingenjörsprogrammet och Textildesignprogrammet på Textilhögskolan i Borås. Textilingenjörerna hade under inledningen av en längre kurs i Polymerteknologi ett introduktionsmoment där studenterna fick en konsumentprodukt tilldelad. Under inledningen av designprojekt hade studenterna på Textildesignprogrammet workshops där de arbetade individuellt eller i grupp. Uppgiften handlade om att utveckla en lösning för skyddad sömn vid en utsatt nödsituation eller att konstruera vävbindningar med hjälp av sin kropp. Enkätundersökningen visade att de flesta som deltagit i introduktionsmomentet av textil-ingenjörerna tyckte att det kändes stimulerande att gruppen själv styrde projektets genomförande vilket inte riktigt alla på textildesignprogrammet höll med om. Här hade man velat ha mer handledning under workshopen. Textilingenjörsstudenterna uppgav i enkäten att introduktionsmomentet hade avgörande betydelse för intresset av hela kursen medan textildesignstudenterna uppgav att introduktionsmomentet inte var lika avgörande för intresset under den fortsatta kursen. Slutligen visade enkätundersökningen att textilingenjörerna i högre grad ville se mer av studentcentrerat lärande utan lärarstyrning

INTERACT: FAIR Data from Cold Region Research Stations

The International Network for Terrestrial Research and Monitoring in the Arctic (INTERACT) is a EU Horizon 2020 funded infrastructure project seeking to provide a geographically comprehensive infrastructure for arctic and high altitude research stations. The overall objective of the project is to facilitate the identification of environmental and ecological change, the understanding of change and prediction of future changes. The second phase of the project commenced October 2016. One of the major tasks in the project is to create a coordinated and unified data management approach that would optimize potential future reuse, sharing, and guarantee data and metadata stewardship and preservation. Herein we present the preliminary plan to carry out this objective by focusing on four principles: Findability, Accessibility, Interoperability, and Reusability (FAIR). Currently, 79 sites in arctic and northern alpine areas are part of the INTERACT network. Data collected at these stations are from different scientific disciplines, e.g. geo-sciences (including the atmosphere and cryosphere), hydrology, biology, ecology, and to some extent anthropology. These data are generated as a result of monitoring activities or short term projects. A survey of data management practices in INTERACT was conducted at the beginning of the project. The main finding is that data management at INTERACT stations is highly heterogeneous. In order to establish a unified view on all the data collected by INTERACT stations and through this show the benefit of INTERACT, interoperability at the discovery metadata and data levels is required. The first step towards this is taken through a Data Management Plan (DMP) which is identifying the general principles, common standards to apply and data dissemination principles. The DMP for INTERACT is a living document oriented towards international data management frameworks like World Meteorological Organization Information System (utilized by e.g. Global Cryosphere Watch, Global Atmosphere Watch), and aligned with the activities of the International Arctic Science Committee (IASC) and Sustaining Arctic Observing Network (SAON) Arctic Arctic Data Committee (ADC). INTERACT emphasizes long term data preservation (as promoted by ICSU-WDS), community driven best practices (e.g. RDA), and the principles outlined by the ADC, that promote free, ethically open, sustained, and timely access to Arctic data. This approach should provide easy integration with the H2020 Open Research Data Pilot, and ensure data access to a variety of stakeholders (e.g. ESA DUE, GlobPermafrost, etc.). The initial data management effort focuses on discovery metadata, utilizing internationally accepted standards, protocols and vocabularies, ensuring the interoperability with international systems and frameworks, and the preservation of scientific legacy. Datasets will be documented using the Global Change Master Directory/Directory Interchange Format or ISO19115 standards. To provide interoperability at the data level, long term archival of data across different national repositories with long term mandates in self-explaining file formats (e.g. NetCDF, HDF/HDF5) is envisioned eventually. Therefore, our goal is to establish a unified approach to metadata and data generated by stations in the INTERACT network. This will be beneficial for scientific purposes, but also for monitoring activities. The latter is particularly important as Arctic monitoring to a large degree rely on the effort of the scientific community

Plasma chemical purification of flue gases using pulsed electron beams

The article presents the study of the pulsed electron beam propagation in oxygen and nitrogen. The researches were performed using the TEA-500 pulsed electron accelerator and drift tube. Parameters of the TEA-500 pulsed electron accelerator are as follows: the electron energy (varies) is 200-450 keV, the beam current is 10 kA, the half-amplitude current pulse duration is 60 ns, the pulse repetition rate is up to 10 Hz (in the pulse burst). The accelerator is equipped with the necessary means of diagnostics of the beam parameters: particle energy, current and current density, the total energy transferred by the beam. The drift tube includes a chamber consisting of two sections of reverse current shunts located along the entire length of the drift tube. The following precursors used N2 and O2. The specified types of gases were chosen as they are among the main components of the flue gases, whose treatment has been widely reported recently