Farming system archetypes help explain the uptake of agri-environment practices in Europe

The adoption of agri-environment practices (AEPs) is crucial for safeguarding the long-term sustainability of ecosystem services within European agricultural landscapes. However, the tailoring of agri-environment policies to the unique characteristics of farming systems is a challenging task, often neglecting local farm parameters or requiring extensive farm survey data. Here, we develop a simplified typology of farming system archetypes (FSAs), using field-level data on farms' economic size and specialisation derived from the Integrated Administration and Control System in three case studies in Germany, Czechia and the United Kingdom. Our typology identifies groups of farms that are assumed to react similarly to agricultural policy measures, bridging the gap between efforts to understand individual farm behaviour and broad agri-environmental typologies. We assess the usefulness of our approach by quantifying the spatial association of identified archetypes of farming systems with ecologically relevant AEPs (cover crops, fallow, organic farming, grassland maintenance, vegetation buffers, conversion of cropland to grassland and forest) to understand the rates of AEP adoption by different types of farms. Our results show that of the 20 archetypes, economically large farms specialised in general cropping dominate the agricultural land in all case studies, covering 56% to 85% of the total agricultural area. Despite regional differences, we found consistent trends in AEP adoption across diverse contexts. Economically large farms and those specialising in grazing livestock were more likely to adopt AEPs, with economically larger farms demonstrating a proclivity for a wider range of measures. In contrast, economically smaller farms usually focused on a narrower spectrum of AEPs and, together with farms with an economic value <2 000 EUR, accounted for 70% of all farms with no AEP uptake. These insights indicate the potential of the FSA typology as a framework to infer key patterns of AEP adoption, thus providing relevant information to policy-makers for more direct identification of policy target groups and ultimately for developing more tailored agri-environment policies

Analysis of Quality Teaching and Learning from Perspective of University Students

This paper presents the results of empirical research focused on the quality of teaching and learning methods, from the perspective of master&rsquo;s students at one of the Czech universities. The research focused on learning outcomes, teaching forms and methods, and the use of ICT technologies following a quantitative survey in this area, which showed the need to examine the topic in depth and in a broader context. Data for the qualitative research were collected through in-depth interviews; the primary research method was focus groups. The data were processed and analysed by coding techniques. The results showed that students prefer teaching and learning outcomes associated with the use in future practice. The teaching forms depend on the teacher&rsquo;s style rather than on the declared description in the curriculum. Contrary to most practices, students prefer teaching methods that lead to active learning. The advantages are identified in the frame of involvement of ICT in teaching, which makes sense and positively impacts students&rsquo; learning; however, the effect depends on how the teaching forms are used

Analysis of Quality Teaching and Learning from Perspective of University Students

This paper presents the results of empirical research focused on the quality of teaching and learning methods, from the perspective of master’s students at one of the Czech universities. The research focused on learning outcomes, teaching forms and methods, and the use of ICT technologies following a quantitative survey in this area, which showed the need to examine the topic in depth and in a broader context. Data for the qualitative research were collected through in-depth interviews; the primary research method was focus groups. The data were processed and analysed by coding techniques. The results showed that students prefer teaching and learning outcomes associated with the use in future practice. The teaching forms depend on the teacher’s style rather than on the declared description in the curriculum. Contrary to most practices, students prefer teaching methods that lead to active learning. The advantages are identified in the frame of involvement of ICT in teaching, which makes sense and positively impacts students’ learning; however, the effect depends on how the teaching forms are used

Applied quadratic programming with principles of statistical paired tests

In applied research areas, various types of mathematical disciplines have been advantageously connected together with wide corresponding applications. As an applied proposal of this connection, a numerical optimization method of the quadratic programming particularly modified by a principle of statistical hypothesis testing can be seen in this paper. With regards to a computational complexity, algorithms of multivariable Model Predictive Control (MPC) can be considered as procedures with a higher computational complexity caused by the multi-variability, higher horizons and included constraints conditions. A wide spectrum of modifications has been proposed in the optimization subsystem of MPC controller yet; however, approaches based on including the hypotheses testing have not been widely considered in applied optimization method. A number of operations should be decreased; however, a control quality may be slightly influenced with regards to this aim. Therefore, the proposed modification is advantageous in an applied form of the quadratic programming technique where necessary information for following steps of a process control are provided. Achieved results are discussed in order to the incorporating of the principle of hypotheses testing in the modified numerical method of the applied quadratic programming. © 2019, Springer Nature Switzerland AG

Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)

International audienc

Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)

Abstract: Background: Patients with minor acute ischemic stroke or transient ischemic attack are at high risk for subsequent stroke, and more potent antiplatelet therapy in the acute setting is needed. However, the potential benefit of more intense antiplatelet therapy must be assessed in relation to the risk for major bleeding. The SOCRATES trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes) was the first trial with ticagrelor in patients with acute ischemic stroke or transient ischemic attack in which the efficacy and safety of ticagrelor were compared with those of aspirin. The main safety objective was assessment of PLATO (Platelet Inhibition and Patient Outcomes)\u2013defined major bleeds on treatment, with special focus on intracranial hemorrhage (ICrH). Methods: An independent adjudication committee blinded to study treatment classified bleeds according to the PLATO, TIMI (Thrombolysis in Myocardial Infarction), and GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) definitions. The definitions of ICrH and major bleeding excluded cerebral microbleeds and asymptomatic hemorrhagic transformations of cerebral infarctions so that the definitions better discriminated important events in the acute stroke population. Results: A total of 13 130 of 13 199 randomized patients received at least 1 dose of study drug and were included in the safety analysis set. PLATO major bleeds occurred in 31 patients (0.5%) on ticagrelor and 38 patients (0.6%) on aspirin (hazard ratio, 0.83; 95% confidence interval, 0.52\u20131.34). The most common locations of major bleeds were intracranial and gastrointestinal. ICrH was reported in 12 patients (0.2%) on ticagrelor and 18 patients (0.3%) on aspirin. Thirteen of all 30 ICrHs (4 on ticagrelor and 9 on aspirin) were hemorrhagic strokes, and 4 (2 in each group) were symptomatic hemorrhagic transformations of brain infarctions. The ICrHs were spontaneous in 6 and 13, traumatic in 3 and 3, and procedural in 3 and 2 patients on ticagrelor and aspirin, respectively. In total, 9 fatal bleeds occurred on ticagrelor and 4 on aspirin. The composite of ICrH or fatal bleeding included 15 patients on ticagrelor and 18 on aspirin. Independently of bleeding classification, PLATO, TIMI, or GUSTO, the relative difference between treatments for major/severe bleeds was similar. Nonmajor bleeds were more common on ticagrelor. Conclusions: Antiplatelet therapy with ticagrelor in patients with acute ischemic stroke or transient ischemic attack showed a bleeding profile similar to that of aspirin for major bleeds. There were few ICrHs. Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01994720.Abstract: BACKGROUND: Patients with minor acute ischemic stroke or transient ischemic attack are at high risk for subsequent stroke, and more potent antiplatelet therapy in the acute setting is needed. However, the potential benefit of more intense antiplatelet therapy must be assessed in relation to the risk for major bleeding. The SOCRATES trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes) was the first trial with ticagrelor in patients with acute ischemic stroke or transient ischemic attack in which the efficacy and safety of ticagrelor were compared with those of aspirin. The main safety objective was assessment of PLATO (Platelet Inhibition and Patient Outcomes)-defined major bleeds on treatment, with special focus on intracranial hemorrhage (ICrH). METHODS: An independent adjudication committee blinded to study treatment classified bleeds according to the PLATO, TIMI (Thrombolysis in Myocardial Infarction), and GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) definitions. The definitions of ICrH and major bleeding excluded cerebral microbleeds and asymptomatic hemorrhagic transformations of cerebral infarctions so that the definitions better discriminated important events in the acute stroke population. RESULTS: A total of 13 130 of 13 199 randomized patients received at least 1 dose of study drug and were included in the safety analysis set. PLATO major bleeds occurred in 31 patients (0.5%) on ticagrelor and 38 patients (0.6%) on aspirin (hazard ratio, 0.83; 95% confidence interval, 0.52-1.34). The most common locations of major bleeds were intracranial and gastrointestinal. ICrH was reported in 12 patients (0.2%) on ticagrelor and 18 patients (0.3%) on aspirin. Thirteen of all 30 ICrHs (4 on ticagrelor and 9 on aspirin) were hemorrhagic strokes, and 4 (2 in each group) were symptomatic hemorrhagic transformations of brain infarctions. The ICrHs were spontaneous in 6 and 13, traumatic in 3 and 3, and procedural in 3 and 2 patients on ticagrelor and aspirin, respectively. In total, 9 fatal bleeds occurred on ticagrelor and 4 on aspirin. The composite of ICrH or fatal bleeding included 15 patients on ticagrelor and 18 on aspirin. Independently of bleeding classification, PLATO, TIMI, or GUSTO, the relative difference between treatments for major/severe bleeds was similar. Nonmajor bleeds were more common on ticagrelor. CONCLUSIONS: Antiplatelet therapy with ticagrelor in patients with acute ischemic stroke or transient ischemic attack showed a bleeding profile similar to that of aspirin for major bleeds. There were few ICrHs