Almanaque-escalafón del cuerpo de penales : 1896-97

En la port.: "Contiene varias disposiciones y datos de sumo interés para los empleados de dicho cuerpo. Año tercero

An Application of the Kaldor-Dixon-Thirlwall Model for Regional Economic Growth in Mexico

This paper analyzes the links between exports and regional economic growth in Mexico.  The Kaldor-Dixon-Thirlwall theoretical model and the econometric methodology of Durbin spatial panel models are used, which were estimated for the periods 2008-2019 and 2008-2023. The econometric results show, among other findings, that the relationship between regional growth and state export growth is null and non-significant, while trade openness and its absolute growth are positive and significant. The weak relationship between exports and regional growth implies that industrial policy proposals other than traditional ones should be promoted. A limitation of this study is the absence of data on regional imports, which could have enabled a more comprehensive examination of theoretical frameworks. Nonetheless,  the study's significance lies in highlighting the limited role of the export sector in driving regional growth in Mexico, attributed to the weakening of national productive links.Una aplicación del modelo Kaldor-Dixon-Thirlwall para el crecimiento regional en MéxicoEn este trabajo se analizan los vínculos entre las exportaciones y el crecimiento económico regional de México. Para ello se utiliza el modelo teórico de Kaldor-Dixon-Thirlwall y la metodología econométrica de modelos Durbin de panel espacial, los cuales fueron estimados para los periodos 2008-2019 y 2008-2023. Los resultados econométricos muestran, entre otros hallazgos, que la relación entre el crecimiento regional y el crecimiento estatal de las exportaciones es nulo y no significativo, mientras que para la apertura comercial y su crecimiento absoluto son positivos y significativos. La evidencia de una relación débil entre las exportaciones y el crecimiento regional implica que se deben impulsar propuestas de política industrial diferentes a las tradicionales. La principal limitación de esta investigación fue la falta de información sobre las importaciones regionales, con las cuales se podrían analizar planteamientos teóricos más completos. La originalidad de este trabajo consiste en mostrar que, para el crecimiento regional en Mexico, el sector exportador en las economías estatales tiene un papel limitado que se explica por el debilitamiento de los vinculos productivos nacionales.

Validation of a Quick Flow Cytometry-Based Assay for Acute Infection Based on CD64 and CD169 Expression. New Tools for Early Diagnosis in COVID-19 Pandemic

Objectives: Several parameters aid in deciphering between viral and bacterial infections; however, new tools should be investigated in order to reduce the time to results and proceed with an early target-therapy. Validation of a biomarker study, including CD64 and CD169 expression, was conducted. Material and Methods: Patients with active SARS-CoV-2 infection (ACov-2), bacterial infection (ABI), healthy controls, and antiretroviral-controlled chronic HIV infection were assessed. Whole blood was stained and, after lysing no-wash protocol, acquired by flow cytometry. The median fluorescence intensity (MFI) of CD64 and CD169 was measured in granulocytes, monocytes, and lymphocytes. The CD64 MFI ratio granulocytes to lymphocytes (CD64N) and CD169 MFI ratio monocytes to lymphocytes (CD169Mo) were evaluated as biomarkers of acute bacterial and viral infection, respectively. Results: A CD64N ratio higher than 3.3 identified patients with ABI with 83.3 and 85.9% sensitivity and specificity, with an area under the curve (AUC) of 83.5%. In contrast, other analytic or hematological parameters used in the clinic had lower AUC compared with the CD64N ratio. Moreover, a CD169Mo ratio higher than 3.3 was able to identify ACov-2 with 91.7 and 89.8 sensitivity and specificity, with the highest AUC (92.0%). Conclusion: This work confirms the previous data of CD64N and CD169Mo ratios in an independent cohort, including controlled chronic viral HIV infection patients as biomarkers of acute bacterial and viral infections, respectively. Such an approach would benefit from quick pathogen identification for a direct-therapy with a clear application in different Health Care Units, especially during this COVID pandemic.This work was partially supported by Instituto de Salud Carlos III Grant: FIS (COV20/0170

Thermal conductivity measurements of macroscopic frozen salt ice analogues of Jovian icy moons in support of the planned JUICE mission

14 páginas, 16 figuras, 2 tablascThe study of thermal properties of frozen salt solutions representative of ice layers in Jovian moons is crucial to support the JUpiter ICy moons Explorer (JUICE) (ESA) and Europa Clipper (NASA) missions, which will be launched in the upcoming years to make detailed observations of the giant gaseous planet Jupiter and three of its largest moons (Ganymede, Europa, and Callisto), due to the scarcity of experimental measurements. Therefore, we have conducted a set of experiments to measure and study the thermal conductivity of macroscopic frozen salt solutions of particular interest in these regions, including sodium chloride (NaCl), magnesium sulphate (MgSO4 ), sodium sulphate (Na2 SO4 ), and magnesium chloride (MgCl2 ). Measurements were performed at atmospheric pressure and temperatures from 0 to −70 ◦C in a climatic chamber. Temperature and calorimetry were measured during the course of the experiments. An interesting side effect of these measurements is that they served to spot phase changes in the frozen salt solutions, even for very low salt concentrations. A small sample of the liquid salt-water solution was set aside for the calorimetry measurements. These experiments and the measurements of thermal conductivity and calorimetry will be valuable to constrain the chemical composition, physical state, and temperature of the icy crusts of Ganymede, Europa, and Callisto.This project received financial support of The European Space Agency (ESA) contracts No.: RFP/3-15589/18/ES/CM and 4000126441/19/ES/CM: ‘Measurements of thermal and dielectric properties of ices in support to future radar measurements of Jovian Icy moons’, The Unidad de Excelencia ‘Mar ́ıa de Maeztu’ MDM-2017-0737– Centro de Astrobiolog ́ıa (INTA-CSIC), The Spanish Ministry of Science, Innovation and Universities AYA2017-85322-R and PID2020-118974GB-C21 (AEI/FEDER, UE), Retos Investigaci ́on BIA2016-77992-R (AEI/FEDER, UE), and ‘Explora Ciencia y Explora Tecnolog ́ıa’ [AYA2017-91062- EXP]. We are grateful to Anezina Solomonidou for assistance in the project proposal. The view expressed in this article can in no way be taken to reflect the official opinion of the European Space Agency. We thank the reviewer of this article for his constructive comments.Peer reviewe

The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation

The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert regulatory and suppressive roles over the immune system. After allogeneic stem cell transplantation, regulatory T cells are known to mitigate graft versus host disease while probably maintaining a graft versus leukemia effect. Short alleles (≤(GT)15) for the (GT)n polymorphism in the promoter/enhancer of FOXP3 are associated with a higher expression of FOXP3, and hypothetically with an increase of regulatory T cell activity. This polymorphism has been related to the development of auto- or alloimmune conditions including type 1 diabetes or graft rejection in renal transplant recipients. However, its impact in the allo-transplant setting has not been analyzed. In the present study, which includes 252 myeloablative HLA-identical allo-transplants, multivariate analysis revealed a lower incidence of grade III-IV acute graft versus host disease (GVHD) in patients transplanted from donors harboring short alleles (OR = 0.26, CI 0.08-0.82, p = 0.021); without affecting chronic GVHD or graft versus leukemia effect, since cumulative incidence of relapse, event free survival and overall survival rates are similar in both groups of patients

El Castru (Vigaña, Balmonte de Miranda, Asturias): un pequeño poblado fortificado de las montañas occidentales cantábricas durante la Edad del Hierro

p. 211-237Este artículo presenta los datos arqueológicos recuperados en las excavaciones del poblado castreño de El Castru, en Vigaña (Balmonte de Miranda, Asturias) realizadas en 2012 y 2013. Dicho yacimiento constituye un buen ejemplo de los pequeños castros de la Edad del Hierro en las montañas del área occidental cantábrica. Por ello, el análisis de las informaciones obtenidas y su contextualización a escala regional ofrecen interesantes aportaciones al debate sobre las formas de poblamiento y subsistencia adoptadas por las comunidades del I milenio a.C. en el Noroeste ibérico.S

Enseñar en Educación Secundaria, un compromiso con la construcción de aprendizajes relevantes y duraderos. Unidades didácticas, secuencias y proyectos, y sus propuestas de evaluación (2019). Parte 3. Propuestas para Ciencias Sociales y Humanidades

Fil: Bovo, Marcos Hernán. Universidad Católica de Córdoba. Facultad de Educación; ArgentinaFil: Bono, Laura Cecilia. Universidad Católica de Córdoba. Facultad de Educación; ArgentinaFil: Ferreyra, Horacio Ademar. Universidad Católica de Córdoba. Facultad de Educación; Argentin

EUSO-SPB1 mission and science

The Extreme Universe Space Observatory on a Super Pressure Balloon 1 (EUSO-SPB1) was launched in 2017 April from Wanaka, New Zealand. The plan of this mission of opportunity on a NASA super pressure balloon test flight was to circle the southern hemisphere. The primary scientific goal was to make the first observations of ultra-high-energy cosmic-ray extensive air showers (EASs) by looking down on the atmosphere with an ultraviolet (UV) fluorescence telescope from suborbital altitude (33 km). After 12 days and 4 h aloft, the flight was terminated prematurely in the Pacific Ocean. Before the flight, the instrument was tested extensively in the West Desert of Utah, USA, with UV point sources and lasers. The test results indicated that the instrument had sensitivity to EASs of ⪆ 3 EeV. Simulations of the telescope system, telescope on time, and realized flight trajectory predicted an observation of about 1 event assuming clear sky conditions. The effects of high clouds were estimated to reduce this value by approximately a factor of 2. A manual search and a machine-learning-based search did not find any EAS signals in these data. Here we review the EUSO-SPB1 instrument and flight and the EAS search

EUSO@TurLab project in view of Mini-EUSO and EUSO-SPB2 missions

The TurLab facility is a laboratory, equipped with a 5 m diameter and 1 m depth rotating tank, located in the fourth basement level of the Physics Department of the University of Turin. In the past years, we have used the facility to perform experiments related to the observations of Extreme Energy Cosmic Rays (EECRs) from space using the fluorescence technique for JEM-EUSO missions with the main objective to test the response of the trigger logic. In the missions, the diffuse night brightness and artificial and natural light sources can vary significantly in time and space in the Field of View (FoV) of the telescope. Therefore, it is essential to verify the detector performance and test the trigger logic under such an environment. By means of the tank rotation, a various terrestrial surface with the different optical characteristics such as ocean, land, forest, desert and clouds, as well as artificial and natural light sources such as city lights, lightnings and meteors passing by the detector FoV one after the other is reproduced. The fact that the tank is located in a very dark place enables the tests under an optically controlled environment. Using the Mini-EUSO data taken since 2019 onboard the ISS, we will report on the comparison between TurLab and ISS measurements in view of future experiments at TurLab. Moreover, in the forthcoming months we will start testing the trigger logic of the EUSO-SPB2 mission. We report also on the plans and status for this purpose