Effect of elastic stockings on biomarkers levels of muscle soreness in volleyball players after exercise

OBJECTIVE:To assess plasma levels of muscle soreness biomarkers, namely creatine kinase, lactate dehydrogenase, and myoglobin, in professional volleyball players following anaerobic exercise with and without the use of elastic stockings. METHODS: Ten female volleyball players aged 18 to 25 years-old were assessed with and without below-knee 20 to 30 mmHg compression stockings (Sport Active®, Venosan, Abreu e Lima, Brazil). Biomarker levels were assessed at three different moments: M0, early in the morning, with the athletes at rest, not using elastic stockings; M1, early in the morning, following a bout of exercise using elastic stockings; M2, seven days later, following the same bout of exercise, however not using elastic stockings. The Borg scale was used after each series of exercise to evaluate the physical effort. RESULTS: The means values obtained for creatine kinase and lactate dehydrogenase were, respectively, 117.7±40.2 and 134.2±11.3 U/L at M0; 138.2±47.2 and 157.9±10.1 U/L at M1; and 161.3±59.9 and 177.2±18.8 U/L at M2. The mean values obtained for myoglobin were 31.5±6.5; 34.9±5.6 and 38.6±12.6 µg/L at the moments M0, M1 and M2, respectively. Statistically significant differences were observed between M1 and M2 (Tukey) for creatine kinase (p=0.0007) and lactate dehydrogenase (p=0.000), but not for myoglobin (p=0.1135). Borg scale scores obtained at M1 and M2 were, respectively, 17.8 and 18.2, without statistically significant differences between them (Wilcoxon). CONCLUSION: The use of elastic stockings was associated with lower plasma levels of biomarkers of muscle injury after exercise.OBJETIVO: Avaliar os níveis plasmáticos dos biomarcadores de lesão muscular, a saber, creatina quinase, lactato desidrogenase e mioglobina, em atletas profissionais de voleibol após exercícios musculares anaeróbicos, com e sem uso de meia elástica. MÉTODOS: Foram avaliadas dez jogadoras profissionais de voleibol, com idades entre 18 e 25 anos, utilizando ou não meia elástica (Sport Active®, Venosan, Abreu e Lima, Brasil), com compressão de 20 a 30 mmHg abaixo do joelho. As dosagens foram feitas em três momentos: M0, início da manhã, com as atletas em repouso sem uso de meia elástica; M1, início da manhã, após a realização de atividade física com uso de meia elástica; M2, sete dias depois, após a realização dos mesmos exercícios, porém sem uso de meia elástica. Aplicou-se a escala de Borg após cada série de atividade física para avaliação do esforço. RESULTADOS: Os valores médios obtidos para creatina quinase e lactato desidrogenase foram, respectivamente, de 117,7±40,2 e 134,2±11,3 U/L, em M0; 138,2±47,2 e 157,9±10,1 U/L, em M1; e 161,3±59,9 e 177,2±18,8 U/L, em M2. Os valores médios obtidos para mioglobina foram de 31,5±6,5; 34,9±5,6 e 38,6±12,6 µg/L nos momentos M0, M1 e M2, respectivamente. Houve diferenças estatisticamente significativas (Tukey) entre M1 e M2 para os valores de creatina quinase (p=0,0007) e lactato desidrogenase (p=0,000), mas não para os valores de mioglobina (p=0,1135). Os escores da escala de Borg em M1 e M2 foram, respectivamente, de 17,8 e 18,2, sem diferença estatisticamente significante entre eles (Wilcoxon). CONCLUSÃO: O uso da meia elástica foi associado a menores níveis plasmáticos dos biomarcadores de lesão muscular após exercício físico.Universidade Federal de São Paulo (UNIFESP)Universidade Federal de Uberlândia Faculdade de MedicinaUFU Instituto de Genética e BioquímicaUNIFESPSciEL

Produção da memória sobre a Guerrilha do Araguaia no documentário “Araguaia: campo sagrado”

From the documentary "Araguaia: Campo Sagrado" (2011), with the direction of Evandro Medeiros and the production of Labor Films, it was intended to seek, in an interpretation of the speeches of the social actors, the production of memory regarding the historical event of the Guerrilla of Araguaia. In order to do so, it was necessary to make an incursion into the history of cinema, identifying and approaching the nonfiction documentary genre as a producer of meanings, not forgetting the perspectives found under its idealizer, as well as focused on the study of the form of construction of history from this filmic genre. The work begins with the study of the military regime experienced in Brazil in the years 1964/1985. It also provides a historical framework on the democratic political regime and human rights, on the armed confrontation and the disparity of forces that took place in the Araguaia. At another point, it was necessary to approach the memory portrayed by Le Goff and Pollak, in order to have a perspective of the collective memory produced. Using the hermeneutics proposed by Gadamer, analyzing the speeches of the subjects present in the documentary, we sought to identify the likely contextualized meaning to the present day. In response, there was a strong oppression of peasants and guerrillas in the Xambioá region and settlements on the Araguaia River in Tocantins and Pará during the confrontation of the Araguaia Guerrilla; the memories then produced are of fear, suffering and aversion to the regime installed at the time, as well as it can be deduced from the speeches of the social subjects that there is still a veiled silence of the hardships then experienced.A partir do documentário “Araguaia: Campo Sagrado” (2011), tendo a direção de Evandro Medeiros e produção de Labour Filmes, pretendeu-se buscar, em uma interpretação das falas dos atores sociais, a produção da memória quanto ao evento histórico da Guerrilha do Araguaia. Para tanto, necessária se fez uma incursão na história do cinema, identificando e abordando o gênero documentário não-ficcional como produtor de sentidos, sem esquecer das perspectivas encontradas sob o olhar de seu idealizador, bem como centrou-se no estudo da forma de construção da história a partir deste gênero fílmico. O trabalho parte para o estudo do regime militar vivenciado no Brasil nos anos de 1964/1985, fazendo um arcabouço histórico, também, sobre o regime político democrático e os direitos humanos, aduzindo sobre o confronto armado e a disparidade de forças ocorrida na Guerrilha do Araguaia. Em outro ponto, foi necessário a abordagem sobre a memória retratada por Le Goff e Pollak, para que se tenha uma perspectiva da memória coletiva produzida. Utilizandose da hermenêutica proposta por Gadamer, analisando as falas dos sujeitos presentes no documentário, buscou-se identificar o provável sentido contextualizado aos dias atuais. Como resposta verificou-se a ocorrência de forte opressão aos camponeses e guerrilheiros na região de Xambioá e povoados às margens do Rio Araguaia no Tocantins e no Pará, durante o confronto da Guerrilha do Araguaia; as memórias então produzidas são de medo, sofrimento e aversão ao regime instalado na época, bem como se depreende das falas dos sujeitos sociais que ainda há um silêncio velado das agruras então vivenciadas

Results of Surgical Treatment Compared with Ultrasound-Guided Foam Sclerotherapy in Patients with Varicose Veins: A Prospective Randomised Study

Objective: This study aims to compare venous clinical severity scores in patients with heated venous ulcers due to varicose veins of the tower limbs (the clinical, etiologic, anatomic, and pathophysiologic data (CEAP) classification: C(5) EpAsPr) treated by saphenous stripping and phlebectomy or by ultrasound-guided foam sclerotherapy.Method: Sixty patients were included: 29 underwent saphenous stripping and phlebectomy for varices in saphenous tributaries and 27 were treated by ultrasound-guided foam sclerotherapy; four cases were lost to follow-up. the main outcome measure was venous clinical severity scores (pain, oedema, inflammation, hyperpigmentation and lipodermatosclerosis). An ultrasound examination was carried out prior to treatment and 30, 60 and 180 days after the procedure to assess the relative efficacy of the methods in obliterating the saphenous trunk.Results: the mean venous clinical severity scores measured before and after 180 days were as follows: Surgery group - pain: before 1.97 standard deviation (SD) 0.19, 180 days 0.72 SD 0,53; oedema: before 1.66 SD 0.48, 180 days 0.55 SD 0.63; inflammation: before 1.55 SD 0.63, 180 days 0.72 SD 0.45. Foam sclerotherapy group - pain: before 1.81 SD 0.40, 180 days 0.56 SD 0.51; oedema: before 1.70 SD 0.47, 180 days 0.48 SD 0.64; inflammation: before 1.67 SD 0.68, after 0.89 SD 0.32. All scores showed statistically significant reductions in both patient groups. the saphenous vein had been obliterated, 180 days after treatment, in 78% of the surgery group, compared with 90% in the foam sclerotherapy group.Conclusions: Ultrasound-guided foam sclerotherapy is a safe and effective option for patients with chronic venous disorders. Crown Copyright (C) 2009 Published by Elsevier Ltd on behalf of European Society for Vascular Surgery. All rights reserved.Universidade Federal de São Paulo, Dept Surg, Vasc Sect, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Surg, Vasc Sect, São Paulo, BrazilWeb of Scienc

Efficacy of intermittent pneumatic compression (IPC) in lower limbs on the blood flow of common femoral veins

BACKGROUND: Prophylaxis of venous thromboembolism, a very common post-surgical complication, can be made pharmacologically or via mechanical methods, such as the use of anti-thrombosis socks and intermittent pneumatic compression (IPC). IPC is a mechanical method of prophylaxis that deserves the attention of the medical community. OBJECTIVE: To evaluate the effect of IPC on the blood flow of common femoral veins in feet, legs and thighs of healthy adults. METHODS: The sample was comprised of 10 volunteers (seven females and three males), adults (20-40 years), without history of venous thromboembolism. After a rest period (10 min), with the patient in the supine position, blood flow was measured (three times) via vascular ultrasonography at the femoral vein, 1 cm above of the saphenofemoral junction, in both limbs, without (control) and with IPC in the patients foot, leg and thigh. Compression (130 mmHg on foot and 45 mmHg on leg and thigh) was applied at compression cycles of 11 seconds and emptying cycles of 20-60 seconds. Blood flow evaluations were performed at compression cycle peaks. Values were compared by analysis of variance (Tukey test), p < 0.05 indicating statistically significant difference. RESULTS: Use of IPC on the left and right lower limbs caused a percentage increase in the femoral blood flow of 37.6 and 70.8% (feet), 143.9 and 164.7% (legs), and 132.6 and 128.9% (thighs), respectively. Variations were statistically significant for application in legs and thighs. CONCLUSION: Use of IPC improves blood flow when applied in legs or thighs.CONTEXTO: A profilaxia do tromboembolismo venoso pode ser feita por métodos farmacológicos ou de forma mecânica, com o uso de meias antitrombo e compressão pneumática (CPI). A CPI é um método mecânico de profilaxia que merece melhor atenção da comunidade médica. OBJETIVO: Avaliar o efeito do uso de compressão pneumática intermitente (CPI) nos pés, pernas e coxas de adultos saudáveis sobre o fluxo sanguíneo nas veias femorais comuns. MÉTODOS: A amostra foi constituída de 10 voluntários (sete mulheres e três homens) adultos (20-40 anos), sem antecedente de tromboembolismo venoso. Após repouso (10 min) em decúbito dorsal, o fluxo sanguíneo era medido (três vezes) por ultra-sonografia vascular na veia femoral, a 1 cm acima da junção safeno-femoral, em ambos os membros, sem controle e com CPI no pé, perna e na coxa. A compressão (130 mmHg no pé e 45 mmHg na perna e na coxa) foi aplicada em ciclos de 11 segundos de compressão e 20-60 segundos de esvaziamento. As aferições de fluxo foram realizadas no pico de fluxo do ciclo de compressão. Os valores foram comparados por análise de variância (teste de Tukey), com p < 0,05 indicando diferença estatisticamente significante. RESULTADO: A utilização de CPI nos membros inferiores, esquerdo e direito, promoveu elevações percentuais relativas no fluxo venoso femoral de 37,6 e 70,8% (pés), 143,9 e 164,7% (pernas) e 132,6 e 128,9% (coxas), respectivamente. As variações foram estatisticamente significantes para as aplicações nas pernas e coxas. CONCLUSÃO: A CPI melhora o fluxo sanguíneo quando aplicada na perna ou na coxa.Universidade Federal de São Paulo (UNIFESP)Universidade Federal de UberlândiaSouthern Illinois UniversityUniversity of Texas Medical BranchUFU Instituto de Genética e BioquímicaUNIFESPSciEL

PRODUÇÃO DA MEMÓRIA SOBRE A GUERRILHA DO ARAGUAIA NO DOCUMENTÁRIO “ARAGUAIA: CAMPO SAGRADO”

From Araguaia: Campo Sagrado (2011), this article sought to carry out a hermeneutic of the narratives of the social actors - peasants - with the focus of the production of memory on the Araguaia Guerrilla. For the elaboration of the research, it was necessary to approach the memory worked by Le Goff (2011) and Pollak (1989) to have a perspective on the collective memory produced. Using the hermeneutics proposed by Gadamer (1999) sought to understand these narratives talks about the subjects present in the film, trying to understand them even in the contemporary perspective. He problematized the oppression of peasants and guerrillas in the region of Xambioá and settlements on the Araguaia River in Tocantins and Pará during the confrontation of the Araguaia Guerrilla. The memories then produced are fear, suffering and aversion to the regime installed at the time, as well as from the speeches of the social subjects interviewed, which are still traumas that have been experienced.Este artículo buscó, a partir de la película "Araguaia: Campo Sagrado" (2011) realizar una hermenéutica de las narrativas de los actores sociales - campesinos - con el enfoque de la producción de la memoria sobre la Guerrilla del Araguaia. Para la elaboración de la investigación, fue necesario el abordaje sobre la memoria trabajada por Le Goff (2011) y Pollak (1989) para que se tenga una perspectiva sobre la memoria colectiva producida. En el caso de la hermenéutica propuesta por Gadamer (1999) buscó comprender estas narrativas de los sujetos presentes en la película, intentando entenderlas incluso en la perspectiva contemporánea. En el marco de la confrontación de la guerrilla del Araguaia, se planteó la opresión a los campesinos y guerrilleros en la región de Xambioá y poblados a orillas del río Araguaia en Tocantins y en Pará. Las memorias entonces producidas son de miedo, sufrimiento y aversión al régimen instalado en la época, así como se desprende de las palabras de los sujetos sociales entrevistados, que aún traumas que fueron vivenciados.Este artigo procurou, a partir do filme “Araguaia: Campo Sagrado” (2011) realizar uma hermenêutica das narrativas dos atores sociais – camponeses – com o enfoque da produção da memória sobre a Guerrilha do Araguaia. Para elaboração da pesquisa, foi necessária a abordagem sobre a memória trabalhada por Le Goff (2011) e Pollak (1989) para que se tenha uma perspectiva sobre a memória coletiva produzida. Utilizando-se da hermenêutica proposta por Gadamer (1999) buscou compreender essas narrativas falas dos sujeitos presentes no filme, tentando entende-las inclusive na perspectiva contemporânea. Problematizou a opressão aos camponeses e guerrilheiros na região de Xambioá e povoados às margens do Rio Araguaia no Tocantins e no Pará, durante o confronto da Guerrilha do Araguaia. As memórias então produzidas são de medo, sofrimento e aversão ao regime instalado na época, bem como se depreende das falas dos sujeitos sociais entrevistados, que ainda traumas que foram vivenciados

Severe cognitive dysfunction and shrinking lung syndrome in systemic lupus erythematous

Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect any organ or system. Neuropsychiatric and pulmonary involvement can occur in 40 and 50% of patients respectively, and may occur in several different clinical forms. While the main neuropsychiatric manifestations are represented by cognitive impairment, organic cerebral syndromes, delirium, psychosis, seizures, and peripheral neuropathies, the main forms of pulmonary involvement are pleurisy with or without pleural effusion, pneumonitis, interstitial disease, pulmonary hypertension, and alveolar hemorrhage. The authors report the case of a 49-year-old woman whose first manifestation of SLE was represented by two rare manifestations: rapidly progressive cognitive impairment, which was associated with respiratory failure caused by the shrinking lung syndrome. The authors call attention to the under-diagnosis of lupus pulmonary complications and its association with severe cognitive impairment that often necessitates aggressive treatment

Characterization of rhizobia indicated for inoculant production using 16S rRNA partial sequencing

O objetivo deste trabalho foi confrontar as sequências parciais do gene 16S rRNA de estirpes padrão de rizóbios com as de estirpes recomendadas para a produção de inoculantes no Brasil, com vistas à verificação da confiabilidade do sequenciamento parcial desse gene para a identificação rápida de estirpes. Foram realizados sequenciamentos através de reação em cadeia da polimerase (PCR) com iniciadores relativos à região codificadora do gene 16S rRNA entre as bactérias estudadas. Os resultados foram analisados pela consulta de similaridade de nucleotídeos aos do "Basic Local Alignment Search Tool" (Blastn) e por meio da interpretação de árvores filogenéticas geradas usando ferramentas de bioinformática. A classificação taxonômica das estirpes Semia recomendadas para inoculação de leguminosas com base em propriedades morfológicas e especificidade hospedeira não foi confirmada em todas as estirpes. A maioria das estirpes estudadas, consultadas no Blastn, é consistente com a classificação proposta pela construção de árvores filogenéticas das sequências destas estirpes, com base na similaridade pelo sequenciamento parcial do gene considerado.The aim of this work was to compare the partial sequences of 16S rRNA gene of rhizobia strain patterns already classified with strains recommended for the production of inoculants in Brazil, in order to verify the reliability of partial sequencing of the gene for the purpose of rapid identification of strains. (PCR) sequencing using primers on the coding region of the 16S rRNA gene among the bacteria studied was conducted. The results were analyzed by consulting the nucleotides' similarity based on Basic Local Alignment Search Tool (Blastn) and by interpreting the phylogenetic trees generated by bioinformatic tools. The taxonomic classification of Semia strains recommended for legume inoculation based on morphological properties and host specificity was not confirmed in all strains. The similarity of the Blastn consultation by partial sequencing of the gene found in strains studied is consistent with the classification proposed by the construction of a phylogenetic tree of sequences of strains in most cases

Acomodações e resistências no trabalho docente às avaliações externas: o que dizem os coordenadores pedagógicos do Rio de Janeiro

Accommodation and resistance in teaching work to external evaluations: what th e pedagogical coordinators of Rio de Janeiro sayResumoEsse artigo tem como temas as avaliações externas da Secretaria Municipal de Educação do Rio de Janeiro (SME-RJ) e a função de professores coordenadores pedagógicos. Como objetivo, a pesquisa qualitativa investigou implicações das avaliações externas ao trabalho de coordenadores pedagógicos, mediadores das políticas curriculares da SME e equipe docente. A partir da análise de conteúdo (Bardin, 1997) realizada em entrevistas semiestruturadas e do diálogo com ideias de Stephen Ball e colaboradores (2016), evidencia-se que avaliações externas acarretam em mudanças no cotidiano escolar e no trabalho docente, tanto em relação à organização cotidiana quanto ao pedagógico. Ocorreram tensões entre as demandas geradas pelas avaliações externas ao trabalho docente, e resistências, quando, a partir de suas interpretações sobre as políticas, procuram manter suas concepções político-pedagógicas.Palavras Chave: Políticas educacionais. Trabalho docente. Avaliação externa. AbstractThis article has as its themes the external evaluations of the Rio de Janeiro Municipal Secretariat of Education (SME-RJ) and the function of pedagogical coordinating teachers. As objective, the qualitative research investigated implications of the external evaluations to the work of pedagogical coordinators, mediators of the curricular policies of the SME and the teaching staff. From the content analysis (Bardin, 1997) conducted in semi-structured interviews and the dialogue with ideas of Stephen Ball and collaborators (2016), it is evident that external evaluations lead to changes in school daily life and teaching work, both in relation to daily organization regarding the pedagogical. There were tensions between the demands generated by evaluations outside the teaching work, and resistances when, from their interpretations of politics, they seek to maintain their political-pedagogical conceptions.Keywords: Educational policies. Teaching work. External evaluation

Ultrastructure of Sheep Primordial Follicles Cultured in the Presence of Indol Acetic Acid, EGF, and FSH

The aim of this study was to investigate the ultrastructural characteristics of primordial follicles after culturing of sheep ovarian cortical slices in the presence of indol acetic acid (IAA), Epidermal Growth Factor (EGF), and FSH. To evaluate ultrastructure of primordial follicles cultured in MEM (control) or in MEM containing IAA, EGF, and FSH, fragments of cultured tissue were processes for transmission electron microscopy. Except in the control, primordial follicles cultured in supplemented media for 6 d were ultrastructurally normal. They had oocyte with intact nucleus and the cytoplasm contained heterogeneous-sized lipid droplets and numerous round or elongated mitochondria with intact parallel cristae were observed. Rough endoplasmic reticulum (RER) was rarely found. The granulosa cells cytoplasm contained a great number of mitochondria and abundant RER. In conclusion, the presence of IAA, EGF, and FSH helped to maintain ultrastructural integrity of sheep primordial follicles cultured in vitro

Prenatal Detection of Congenital Heart Diseases: One-Year Survey Performing a Screening Protocol in a Single Reference Center in Brazil

Objective. To describe the experience of a tertiary center in Brazil to which patients are referred whose fetuses are at increased risk for congenital heart diseases (CHDs). Methods. This was a cross-sectional observational study. The data was collected prospectively, during the year 2012, through a screening protocol of the fetal heart adapted from the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) guideline. We performed a fetal echocardiogram screening for all pregnant women who were referred to the fetal cardiology outpatient obstetrics clinic of a university hospital. The exams were classified as normal or abnormal. The cases considered abnormal were undergone to a postnatal echocardiogram. We categorized the abnormal fetal heart according to severity in “complex,” “significant,” “minor,” and “others.” Results. We performed 271 fetal heart screening. The incidence of abnormal screenings was 9.96% (27 fetuses). The structural CHD when categorized due to severity showed 48.1% (n=13) of “complex” cases, 18.5% (n=5) “significant” cases, and 7.4% (n=2) “minor” cases. The most common referral reason was by maternal causes (67%) followed by fetal causes (33%). The main referral indication was maternal metabolic disease (30%), but there was just one fetus with CHD in such cases (1.2%). CHDs were found in 19/29 fetuses with suspicion of some cardiac abnormality by obstetrician (65.5%). Conclusion. We observed a high rate of CHD in our population. We also found that there was higher incidence of complex cases