119 research outputs found
Miejsca nagłej śmierci w Poznaniu – ich typologia i formy upamiętnienia
W artykule przedstawiono typologię i formy upamiętniania miejsc nagłej śmierci w Poznaniu na podstawie inwentaryzacji tych miejsc przeprowadzonej w latach 2016–2017. Typologii miejsc nagłej śmierci dokonano w oparciu o 4 kryteria: (1) formę upamiętnienia miejsca wypadku, (2) położenia miejsca pamięci względem kategorii dróg publicznych, (3) położenia względem centrum miasta oraz (4) położenia w układzie wertykalnym miasta. Z uwagi na pierwsze kryterium przeprowadzono szerszą charakterystykę tych miejsc. W przestrzeni publicznej Poznania wyróżniono aż 12 form upamiętnienia miejsc nagłej śmierci, z których znicze, przydrożne krzyże i kwiaty występują najczęściej, natomiast rzadkim sposobem upamiętnienia zmarłego w miejscu wypadku jest biały rower
Odwiedzenia nekropolii na Miłostowie w Poznaniu i ich motywy
W artykule podjęto próbę określenia natężenia i częstotliwości odwiedzeń cmentarza na Miłostowie jako największej poznańskiej nekropolii, a także wyznaczenia zasięgu jego oddziaływania na podstawie miejsca zamieszkania odwiedzających cmentarz oraz wskazania motywów odwiedzeń przestrzeni sepulkralnej, którymi kierują się podróżujący do takich właśnie miejsc. Podstawą analiz były przede wszystkim wyniki badań ankietowych przeprowadzonych wśród 300 osób, jak również zebrane w drodze pomiaru bezpośredniego dane statystyczne dotyczące natężenia ruchu pieszych wchodzących na cmentarz
„Projektowanie włączające” – proces projektowania nowoczesnych technologii z aktywnym udziałem adresatów rozwiązań
Projekt finansowany ze środków Narodowego Centrum Badań i Rozwoju w ramach programu „Innowacje społeczne”. Doniesienie z etapu badań „System elektronicznego wspomagania samodzielności życiowej osób z niepełnosprawnością intelektualną”
The life of adults with intellectual disabilities – a problematic implementation of necessary sexuality and independence in the context of the development of identity
The author emphasizes the influence of social attitudes towards an individual on his or her self-perception and also pays attention to what threatens the development of identity in people with intellectual disability. It is said that the most important thing in the process of identity formation is the fulfillment of three basic psychological needs during adulthood: the need for having positive relations with other people, the need for autonomy and the need for competence. The limited opportunities of adult women and men with intellectual disability to realize these needs are connected to attitudes towards people with intellectual disability such as over-protectiveness, compassion, focus on deficits, ignorance, segregation, control and judgments. These attitudes are generated by a set of social stereotypes, according to which a person with intellectual disability is an “ageless child”. People with intellectual disabilities are affected by a lack of autonomy, the impossibility of experiencing their own competence as well as limited social contacts as they stay under control of their closest social environment. These problems are concerned with the areas of sexuality and independent living. The author provides examples of discriminatory attitudes as well as current stereotypes and social beliefs which are an actual barrier to the psychosocial functioning of adult people with intellectual disability with respect to the realization of their sexual needs and needs for autonomy.The author emphasizes the influence of social attitudes towards an individual on his or her self-perception and also pays attention to what threatens the development of identity in people with intellectual disability. It is said that the most important thing in the process of identity formation is the fulfillment of three basic psychological needs during adulthood: the need for having positive relations with other people, the need for autonomy and the need for competence. The limited opportunities of adult women and men with intellectual disability to realize these needs are connected to attitudes towards people with intellectual disability such as over-protectiveness, compassion, focus on deficits, ignorance, segregation, control and judgments. These attitudes are generated by a set of social stereotypes, according to which a person with intellectual disability is an “ageless child”. People with intellectual disabilities are affected by a lack of autonomy, the impossibility of experiencing their own competence as well as limited social contacts as they stay under control of their closest social environment. These problems are concerned with the areas of sexuality and independent living. The author provides examples of discriminatory attitudes as well as current stereotypes and social beliefs which are an actual barrier to the psychosocial functioning of adult people with intellectual disability with respect to the realization of their sexual needs and needs for autonomy
People with disabilities who live in the country – barriers to social inclusion
The main argument of the article is the statement that the barriers of social activity and professional work for people with disabilities pile up when she or he lives in the countryside – in rural areas can be observed the accumulation phenomena impact on social marginalization. This article aims to analyze the socio-economic, communications, institutional, environmental and social obstacles that limit social participation of people with disabilities. Negative and marginalizing characteristics of the rural environment is first and foremost a low economic level, architectural barriers and difficulties in access to educational infrastructure, social and cultural data communications. The effect of this are unrealized rules of normalization of people with disabilities living in a village in areas such as education, work and leisure activities. Disparities between urban and rural areas in this field decides with fewer opportunities of development and social integration of disabled villagers.The main argument of the article is the statement that the barriers of social activity and professional work for people with disabilities pile up when she or he lives in the countryside – in rural areas can be observed the accumulation phenomena impact on social marginalization. This article aims to analyze the socio-economic, communications, institutional, environmental and social obstacles that limit social participation of people with disabilities. Negative and marginalizing characteristics of the rural environment is first and foremost a low economic level, architectural barriers and difficulties in access to educational infrastructure, social and cultural data communications. The effect of this are unrealized rules of normalization of people with disabilities living in a village in areas such as education, work and leisure activities. Disparities between urban and rural areas in this field decides with fewer opportunities of development and social integration of disabled villagers
Regional diversification of financial situation of the horticultural farms in European Union countries
PURPOSE: This article aims to identify the financial situation of the horticultural farms in
Poland compared to their counterparts in other European Union countries in 2012-2017 in
the synthetic context.DESIGN/METHODOLOGY/APPROACH: To achieve this purpose, the data from the FADN database
on horticultural farms from macro-regions in EU countries in 2012-2017 were used. To assess
the financial situation, a synthetic measuring instrument of development was used, and the
non-pattern method was employed to construct it.FINDINGS: The results of the conducted research show that the horticultural farms are
characterised by differentiation of economic effects. These results affect their financial
situation, which in turn determines their possibility of further market development, that is the
economic safety of farm families, as well as the supply safety of food consumers.PRACTICAL IMPLICATIONS: Obtained studies results can be used by EU agricultural policymakers
and the horticultural farm owners. The results indicate in which regions the horticultural
farms have more development opportunities and in which the economic safety of farm families
is in danger.ORIGINALITY/VALUE: The results of the conducted analysis are complementary to the previous
studies on the financial situation of the horticultural farms. Additionally, the article proposed
the straight-line ordering method to assess the financial situation of the horticultural farms.The project was co-financed with the resources of the National Science
Centre, allocated pursuant to decision No. DEC-2012/05/B/HS4/04134.peer-reviewe
The role of vitamin D in the human body and the benefits and risks of its supplementation
The prevalence of vitamin D deficiency in society and the growing awareness of related health problems have resulted in the widespread use of vitamin D supplementation. The source of vitamin D is skin synthesis with the participation of ultraviolet radiation (UVB) and its supply with the diet. The inability to cover the daily requirement for vitamin D without an additional source of vitamin D means that the society most often reaches for dietary supplements that do not have the properties of a medicinal product. The use of over-the-counter supplements, where the actual dose of the vitamin may differ from the dose declared by the manufacturers, may result in a lack of benefit from the food product when the vitamin D content is too low or lead to hypervitaminosis when the content is too high
Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L
The research was partially supported by Grant No. 2021/41/B/NZ9/01054 from the National Science Centre (Poland). AU was supported by a scholarship from the Polish National Agency for Academic Exchange (NAWA) within the Bekker Programme, 2019 (personal stipend, PPN/BEK/2019/1/00167), a scholarship from the Deutscher Akademischer Austauschdienst (DAAD) within the program for Research Stays for University Academics and Scientists, 2018 (personal stipend, 91696887), and a scholarship from the Initiative of Excellence, Research University (ID-UB Project), within the International Junior and Senior Exchange, 2021 (personal stipend, 018/07/POB2/0001). The publication fee was supported by the ID-UB Project (040/08/POB2/0010). JR was funded by DFG FOR 5026.Tachykinins (TKs) are a group of conserved neuropeptides. In insects, tachykinin-related peptides (TRPs) are important modulators of several functions such as nociception and lipid metabolism. Recently, it has become clear that TRPs also play a role in regulating the insect immune system. Here, we report a transcriptomic analysis of changes in the expression levels of immune-related genes in the storage pest Tenebrio molitor after treatment with Tenmo-TRP-7. We tested two concentrations (10-8 and 10-6 M) at two time points, 6 and 24 h post-injection. We found significant changes in the transcript levels of a wide spectrum of immune-related genes. Some changes were observed 6 h after the injection of Tenmo-TRP-7, especially in relation to its putative anti-apoptotic action. Interestingly, 24 h after the injection of 10-8 M Tenmo-TRP-7, most changes were related to the regulation of the cellular response. Applying 10-6 M Tenmo-TRP-7 resulted in the downregulation of genes associated with humoral responses. Injecting Tenmo-TRP-7 did not affect beetle survival but led to a reduction in haemolymph lysozyme-like antibacterial activity, consistent with the transcriptomic data. The results confirmed the immunomodulatory role of TRP and shed new light on the functional homology between TRPs and TKs.Peer reviewe
Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L.
Tachykinins (TKs) are a group of conserved neuropeptides. In insects, tachykinin-related peptides (TRPs) are important modulators of several functions such as nociception and lipid metabolism. Recently, it has become clear that TRPs also play a role in regulating the insect immune system. Here, we report a transcriptomic analysis of changes in the expression levels of immune-related genes in the storage pest Tenebrio molitor after treatment with Tenmo-TRP-7. We tested two concentrations (10–8 and 10–6 M) at two time points, 6 and 24 h post-injection. We found significant changes in the transcript levels of a wide spectrum of immune-related genes. Some changes were observed 6 h after the injection of Tenmo-TRP-7, especially in relation to its putative anti-apoptotic action. Interestingly, 24 h after the injection of 10–8 M Tenmo-TRP-7, most changes were related to the regulation of the cellular response. Applying 10–6 M Tenmo-TRP-7 resulted in the downregulation of genes associated with humoral responses. Injecting Tenmo-TRP-7 did not affect beetle survival but led to a reduction in haemolymph lysozyme-like antibacterial activity, consistent with the transcriptomic data. The results confirmed the immunomodulatory role of TRP and shed new light on the functional homology between TRPs and TKs
Vitamin D supplementation in Polycystic ovary syndrome
Introduction and Purpose. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age worldwide. Patients may present with a wide range of symptoms. According to the most commonly used Rotterdam criteria, the presence of 2 out of 3 criteria is required for diagnosis: clinical and/or biochemical markers of hyperandrogenism (HA); ovulation disorders (oligo- or anovulation); polycystic ovaries on ultrasound (PCOM); and exclusion of disorders mimicking the clinical features of PCOS. The basis of treatment are birth control pills, metformin and antiandrogens. The pathogenesis of the syndrome is not fully understood. The aim of the study is to summarize the potential health benefits of vitamin D supplementation for women with PCOS based on publications from the last 10 years available on Pubmed. State of knowledge. Vitamin D receptors have been identified not only in calcium-regulating tissues, but also in many reproductive organs, such as the ovary (especially granulosa cells), uterus, placenta, testes, as well as hypothalamus and pituitary gland. In recent years, there have been studies analyzing the effect of vitamin D supplementation on the hormonal balance, metabolism and clinical symptoms in women with PCOS. Summary. The results of studies on vitamin D supplementation in women with PCOS are mixed. Some of them are promising and confirm a beneficial effect on glucose metabolism and insulin resistance, lipid metabolism, hormonal balance, alleviation of HA-related symptoms, improvement of menstrual frequency; while the results of other studies do not show significant improvement and do not confirm these effects. Therefore, there is a need for further research on the relationship between the pathogenesis of PCOS and vitamin D and the impact of its supplementation
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