Deklaratywny UI Framework dla platformy .NET

Celem pracy jest zaprojektowanie narzędzia dla platformy .NET, które umożliwi programiście tworzenie interfejsów użytkownika. Projekt zakłada stworzenie UI Frameworka, z którego wykorzystaniem programista może budować drzewa komponentów w sposób deklaratywny. Framework we własnym zakresie obsługuje procesy renderowania, umożliwia elastyczne pozycjonowanie i wymiarowanie komponentów, oraz dostarcza system stylowania dzięki któremu można w przystępny sposób kontrolować wyglądem stworzonego interfejsu. Framework powinien dodatkowo obsługiwać interakcję końcowego użytkownika z interfejsem za pomocą myszy i klawiatury. Efektem pracy jest działający UI Framework dzięki któremu programista w może prosto i szybko tworzyć dobrze wyglądające aplikacje dla platformy .NET.The purpose of this project is to design a tool for the .NET platform that will enable a way for programmer to create user interfaces. The project involves the creation of a UI Framework with which a developer can build component trees by using declarative programming paradigm. The framework handles rendering processes on its own, allows flexible positioning and dimensioning of the components, and provides a styling system that provides control of the created interface's appearance in an accessible way. The framework should additionally support end-user interaction with the interface using the mouse and keyboard. The result of the work is a working UI Framework, where the programmer can easily and quickly create good-looking applications for the .NET platform

The impact of the assimilation of migrants on the well-being of native inhabitants: A theory

We present a theory that systematically and causally links the well-being of native inhabitants with variation in the extent of the assimilation of migrants. Recent empirical findings are yielded as predictions of the theory

Russian “hard power” and “soft power” in influencing central and eastern European countries on the example of Poland in the COVID-19 era

Purpose: An attempt was made to determine the scope and actual implications resulting from the use of the Russian "hard power" and "soft power" concerning the CEE countries in the COVID-19 era based on the Russian impact on Poland in the period 2019/2020. Design/Methodology/Approach: The substantive components of the impact under study were obtained through a study. A synthesis method was applied, which allowed for grouping the originally separated components into three basic currents of hard influences: political, political-economic, and paramilitary. The comparison method was used to verify such a division of the Russian hard current and, if such a division is confirmed, to highlight the existing differences - especially between the first and second current. In the course of research on the methodology of the Kremlin's soft impact on the Polish decision-making process, the method of reviewing source materials of recognized reliability was used (query of scientific literature and expert studies), which were compared with quantitatively collected data obtained from media information to supplement the whole source material. The conclusions were formulated using induction and deduction methods. Findings: The Russian Federation uses political and economic and economic measures in the first place to influence using "hard power," and if it is not possible to influence such measures, it uses paramilitary measures. In the case of soft power impact, the Russian Federation mainly uses informational means in the form of so-called "social engineering" methodology (propaganda), where the main area of activity is virtual space. Practical Implications: This paper can be used in scientific and expert work dedicated to the Russian methodology of impact using "hard power" and "soft power." Originality/Value: Lack of comprehensive scientific studies dedicated to the methodology of using "hard power" and "soft power" means by the Russian Federation during the COVID-19 2019/2020 epidemic.peer-reviewe

Geopolitical strategy of the Russian Federation in relation to the epicenter of the visegrad group on the example of Poland in the COVID-19 pandemic

Purpose: An attempt to determine the possibility of using the global epidemic's state to implement geopolitical objectives by the Russian Federation on the example of Poland in the wider context of international geopolitical conditions around the Visegrad Group. Design/Methodology/Approach: The paper uses mainly source texts and the content of expert interviews conducted at the turn of 2019/2020. The collected empirical data were then processed using theoretical methods such as analysis, synthesis, and comparison to formulate conclusions using deductive and inductive inference methods. Findings: It has been confirmed that in their foreign policy, the decision-making centers of the Russian Federation are willing to take advantage of the situation of the global epidemic to achieve their own geopolitical goals concerning other countries. Practical Implications: This study may be used in scientific and expert work on the Russian Federation's foreign policy in the COVID-19 era. Originality/Value: Lack of comprehensive scientific studies dedicated to implementing the Russian Federation's geopolitical objectives during the COVID-19 2019/2020 epidemic.peer-reviewe

Metal-free synthesis of indanes by iodine(III)-mediated ring contraction of 1, 2-dihydronaphthalenes

A metal-free protocol was developed to synthesize indanes by ring contraction of 1, 2-dihydronaphthalenes promoted by PhI(OH)OTs (HTIB or Koser's reagent). This oxidative rearrangement can be performed in several solvents (MeOH, CH3CN, 2 , 2, 2-trifluoroethanol (TFE), 1 , 1, 1, 3, 3, 3-hexafluoroisopropanol (HFIP), and a 1:4 mixture of TFE:CH2Cl2) under mild conditions. The ring contraction diastereoselectively gives functionalized trans-1, 3-disubstituted indanes, which are difficult to obtain in synthetic organic chemistryUm protocolo livre de metais foi desenvolvido para sintetizar indanos através da contração de anel de 1, 2-di-hidronaftalenos promovida por PhI(OH)OTs (HTIB ou reagente de Koser). Este rearranjo oxidativo pode ser realizado em diversos solventes (MeOH, CH3CN, 2 , 2, 2-trifluoroetanol (TFE), 1 , 1, 1, 3, 3, 3-hexafluoroisopropanol (HFIP), e uma mistura 1:4 de TFE:CH2Cl2) em condições brandas. A contração de anel fornece indanos trans-1, 3-dissubstituídos diastereosseletivamente, os quais são difíceis de obter em química orgânica sintéticaFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FAPES

Multicenter registry of Impella-assisted high-risk percutaneous coronary interventions and cardiogenic shock in Poland (IMPELLA-PL)

Background: Impella is a percutaneous mechanical circulatory support device for treatment of cardiogenic shock (CS) and high-risk percutaneous coronary interventions (HR-PCIs). IMPELLA-PL is a national retrospective registry of Impella-treated CS and HR-PCI patients in 20 Polish interventional cardiological centers, conducted from January 2014 until December 2021.Aims: We aimed to determine the efficacy and safety of Impella using real-world data from IMPELLA-PL and compare these with other registries.Methods: IMPELLA-PL data were analyzed to determine primary endpoints: in-hospital mortality and rates of mortality and major adverse cardiovascular and cerebrovascular events (MACCE) at 12 months post-discharge.Results: Of 308 patients, 18% had CS and 82% underwent HR-PCI. In-hospital mortality rates were 76.4% and 8.3% in the CS and HR-PCI groups, respectively. The 12-month mortality rates were 80.0% and 18.2%, and post-discharge MACCE rates were 9.1% and 22.5%, respectively. Any access site bleeding occurred in 30.9% of CS patients and 14.6% of HR-PCI patients, limb ischemia in 12.7% and 2.4%, and hemolysis in 10.9% and 1.6%, respectively.Conclusions: Impella is safe and effective during HR-PCIs, in accordance with previous registry analyses. The risk profile and mortality in CS patients were higher than in other registries, and the potential benefits of Impella in CS require investigation

Efficient and High-Yielding Routes to Diaryliodonium Salts

This thesis summarizes three novel and general reaction protocols for the synthesis of diaryliodonium salts. All protocols utilize mCPBA as oxidant and the acids used are either TfOH, to obtain triflate salts, or BF3•Et2O that gives the corresponding tetrafluoroborate salts in situ. Chapter two describes the reaction of various arenes and aryl iodides, delivering electron-rich and electron-deficient triflates in moderate to excellent yields. In chapter three, it is shown that the need of aryl iodides can be circumvented, as molecular iodine can be used together with arenes in a direct one-pot, three-step synthesis of symmetric diaryliodonium triflates. The final and fourth chapter describes the development of a sequential one-pot reaction from aryl iodides and boronic acids, delivering symmetric and unsymmetric, electron-rich and electron-deficient iodonium tetrafluoroborates in moderate to excellent yields. This protocol was developed to overcome mechanistic limitations existing in the protocols described in chapter two and three. The methodology described in this thesis is the most general, efficient and high-yielding existing up to date, making diaryliodonium salts easily available for various applications in synthesis

Diaryliodonium Salts : Development of Synthetic Methodologies and α-Arylation of Enolates

This thesis describes novel reaction protocols for the synthesis of diaryliodonium salts and also provides an insight to the mechanism of α-arylation of carbonyl compounds with diaryliodonium salts.  The first chapter gives a general introduction to the field of hypervalent iodine chemistry, mainly focusing on recent developments and applications of diaryliodonium salts. Chapter two describes the synthesis of electron-rich to electron-poor diaryliodonium triflates, in moderate to excellent yields from a range of arenes and iodoarenes. In chapter three, it is described that molecular iodine can be used together with arenes in a direct one-pot, three-step synthesis of symmetric diaryliodonium triflates. A large scale synthesis of bis(4-tert-butylphenyl)iodonium triflate is also described, controlled and verified by an external research group, further demonstrating the reliability of this methodology. The fourth chapter describes the development of a sequential one-pot synthesis of diaryliodonium salts from aryl iodides and boronic acids, furnishing symmetric and unsymmetric, electron-rich to electron-poor diaryliodonium tetrafluoroborates in moderate to excellent yields. This method was developed to overcome the regiochemical limitations imposed by the reaction mechanism in the protocols described in the preceding chapters. Chapter five describes a one-pot synthesis of heteroaromatic iodonium salts under similar conditions described in chapter two. The final chapter describes the reaction of enolates with chiral diaryliodonium salts or together with a phase transfer catalyst yielding racemic products. DFT calculations were performed, which revealed a low lying energy transition state (TS) between intermediates, which is believed to be responsible for the lack of selectivity observed in the experimental work. It is also proposed that a [2,3] rearrangement is preferred over a [1,2] rearrangement in the α-arylation of carbonyl compounds. The synthetic methodology described in this thesis is the most generally applicable, efficient and high-yielding to date for the synthesis of diaryliodonium salts, making these reagents readily available for various applications in synthesis