Proportionally modular affine semigroups

Producción CientíficaThis work introduces a new kind of semigroup of Np called proportionally modular affine semigroup. These semigroups are defined by modular Diophantine inequalities and they are a generalization of proportionally modular numerical semigroups. We give an algorithm to compute their minimal generating sets. We also specialize on the case p = 2. For this case, we provide a faster algorithm to compute their minimal system of generators, prove they are Cohen-Macaulay and Buchsbaum, and determinate their (minimal) Frobenius vectors. Besides, Gorenstein proportionally modular affine semigroups are characterized.Ministerio de Economía, Industria y Competitividad ( grants MTM2014-55367-P / MTM2015-65764- C3-1-P)Junta de Andalucía (FQM-366 / FQM-298

Institutions and business customer experience: the role of interfunctional coordination and service co-design.

This paper contributes to a better understanding of the complex phenomenon of institutions and the moderation of the main antecedents of business customer experience. Following a combination of literature review and three fieldworks, the main antecedents of business customer experience have emerged: interfunctional coordination, customer engagement and participation in the co-design of services. The role of institutions (level of formalisation) has also been considered as a possible moderator. Consequently, a conceptual framework has been developed which includes seven research propositions. The first four research propositions are related to the main elements of the model and suggest new relationships among constructs. The other three research propositions are suggested and empirically examined using Fuzzy-Set Qualitative Comparative Analysis to find causal configurations and to identify pathways that lead to business customer experience. Necessity and sufficiency of conditions that lead to a positive business customer experience are discussed for both scenarios of high and low formalisation of institutions

Characterization of terrestrial hot particles from the Palomares accident using destructive and non-destructive analytical techniques

Several radioactive particles from the Palomares area have been analyzed with the nuclearmicroprobe of the National Accelerator Centre (CNA) in Seville exploring the advantages of combining -PIXE using a 5.5 MeV4He beam with conventional -PIXE analysis using 3 MeV protons. Themeasurements performed with the -particles are more sensitive to the sample surface, while the resultscollected with protons are indicative of the average composition of the hot particle. In this way, importantinformation about the depth distribution of Pu and U in the particles has been obtained. In addition, theparticles have been analyzed by SEM (EDX) and one of them has been sacrificed for the determinationof its U and Pu isotopic composition by ICP-MS and -spectrometry, being gained in this way importantinformation about the composition of the weapons involved in the Palomares accident.Junta de Andalucía Excellence Project TU-DRAMA (Ultra-sensitive techniques for radionuclides determination in environmental materials

Fluxes of the 238U-series isotopes in the industrial production of dicalcium phosphate and the radiological impact due to the incorporation to poultry diets

La roca de fosfato se utiliza como fuente para la producción de suplementos alimenticios, como en forma de fosfato dicálcico (DCP), que es un suministro de calcio y fósforo para animales domésticos

Capillary microfluidic platform for sulfite determination in wines

A microfluidic paper-based analytical device integrating a chromoreactand – a formylazo dye– has been fabri- cated and used for a colorimetric assay of sulfites. The chromoreactand was covalently linked to paper by vinyl sulfone chemistry. This work presents two robust capillary microfluidic devices to determine sulfite in wine without any pretreatment. One of them based on thread (µTPAD) useful to determine it in white wine and another based on paper (µPAD) to specifically determine sulfite in red wine as well as in white wine. Both are based on the selective recognition of sulfite by means of a chromoreactand that turns from orange to yellow in the presence of sulfite. The colour information acquired (H coordinate) using a digital camera readout allows for a range of appli- cation of the µTPAD from 7.8⋅10−5 M (8.1 mg L−1) to 2.7⋅10−3 M (279.3 mg L−1) with a limit of detection (LOD) of 78 µM. The strong interference caused by the dyes present in red wine is eliminated by including a laminated paper channel in the µPAD structure that allows for the separation of colorants from red wine before the recognition of the sulfite. This makes it possible to adjust the µPAD procedure to the usual sulfite concentration in wine, with an LOD of 2.2⋅10−4 M (22.7 mg L−1) and a CV of 2.6%.This work was founded by Spanish “Ministerio de Economía y Competitividad” (Projects PID2019-103938RB-I00) and Junta de Andalucía (Projects B-FQM-243-UGR18 and P18-RT-2961). The projects were partially supported by European Regional Development Funds (ERDF)

Recomendaciones basadas en la evidencia del grupo andaluz para la reflexión e investigación en nutrición (Garin) para el manejo del paciente con síndrome de intestino corto

In order to develop evidence-based recommendations and expert consensus for the nutritional management of patients with short bowel syndrome (SBS), we conducted a systematic literature search using the PRISMA methodology plus a critical appraisal following the GRADE scale procedures. Pharmacological treatment with antisecretory drugs, antidiarrheal drugs, and somatostatin contributes to reducing intestinal losses. Nutritional support is based on parenteral nutrition; however, oral intake and/or enteral nutrition should be introduced as soon as possible. In the chronic phase, the diet should have as few restrictions as possible, and be adapted to the SBS type. Home parenteral nutrition (HPN) should be individualized. Single-lumen catheters are recommended and taurolidine should be used for locking the catheter. The HPN’s lipid content must be greater than 1 g/kg per week but not exceed 1 g/kg per day, and omega-6 fatty acids (ω6 FAs) should be reduced. Trace element vials with low doses of manganese should be used. Patients with chronic SBS who require long-term HPN/fluid therapy despite optimized treatment should be considered for teduglutide treatment. All patients require a multidisciplinary approach and specialized follow-up. These recommendations and suggestions regarding nutritional management in SBS patients have direct clinical applicability

Desarrollo de un método de transcripción inversa seguida de reacción en cadena de la polimerasa para la detección del virus de la fiebre amarilla

Introduction. Yellow fever is considered a re-emerging disease and is endemic in tropical regions of Africa and South America. At present, there are no standardized or commercialized kits available for yellow fever virus detection. Therefore, diagnosis must be made by time-consuming routine techniques, and sometimes, the virus or its proteins are not detected. Furthermore, co-circulation with other flaviviruses, including dengue virus, increases the difficulty of diagnosis.Objective. To develop a specific reverse transcriptase-polymerase chain reaction (RT-PCR) and nested PCR-based assay to improve the detection and diagnosis of yellow fever virus using both serum and fresh tissue samples.Materials and methods. RT-PCR primers were designed to amplify a short fragment of all yellow fever virus genotypes reported. A second set of primers was used in a nested PCR to increase sensitivity. Thirty-three clinical samples were tested with the standardized reaction.Results. The expected amplicon was obtained in 25 out of 33 samples analyzed using this approach, and 2 more samples tested positive after a subsequent nested PCR approach.Conclusion. This improved technique not only ensures the specific detection of a wide range of yellow fever virus genotypes but also may increase the sensitivity of detection by introducing a second round of amplification, allowing a rapid differential diagnosis between dengue and yellow fever infection, which is required for effective surveillance and opportune epidemiologic measures. doi: http://dx.doi.org/10.7705/biomedica.v33i0.1452Introducción. La fiebre amarilla se considera una enfermedad reemergente y endémica en regiones tropicales de África y Suramérica. Actualmente, no existen estuches estandarizados o comerciales disponibles para la detección del virus de la fiebre amarilla y, por lo tanto, el diagnóstico debe hacerse mediante técnicas de rutina que consumen mucho tiempo y algunas veces no garantizan la detección del virus o de sus proteínas. Además, la cocirculación con otros flavivirus, incluyendo el del dengue, hacen el diagnóstico más complicado.Objetivo. Desarrollar un ensayo específico de amplificación basado en transcripción inversa seguida de reacción en cadena de la polimerasa, con el fin de mejorar la detección y el diagnóstico de la fiebre amarilla, tanto a partir de suero como de tejido fresco.Materiales y métodos. Se diseñaron iniciadores específicos para amplificar un fragmento conservado del virus de la fiebre amarilla. Un segundo par de iniciadores se usó en una reacción de amplificación anidada para incrementar la sensibilidad. Se probaron 33 muestras clínicas con la técnica estandarizada.Resultados. El amplímero esperado se obtuvo en 25 de las 33 muestras analizadas usando este método y 2 más resultaron positivas después de la reacción anidada.Conclusión. Esta técnica mejorada garantiza la detección de todos los genotipos virales de fiebre amarilla y puede incrementar la sensibilidad del ensayo introduciendo una segunda etapa de amplificación, lo cual permite el diagnóstico diferencial con infección por dengue y otros flavivirus, lo cual es de gran importancia para la vigilancia y la toma de medidas epidemiológicas oportunas.doi: http://dx.doi.org/10.7705/biomedica.v33i0.1452

Estudio de las características físico–químicas de las aguas del Balneario de San Nicolás (Almería)

Las aguas del balneario de San Nicolás, de Alhama de Almería, fueron declaradas de utilidad pública por Real Orden de 16 de mayo de 1877, bajo la denominación de aguas de Alhama la Seca; en 1928 fue confirmada la utilidad pública de las aguas minero-medicinales de Alhama de Almería. Existen diferentes estudios de las aguas de este balneario, especialmente en el siglo XIX, en los que se comenta el tipo de aguas y su clasificación, y la mayoría de autores hacen referencia a una temperatura de las mismas superior a 40ºC. Se analizaron las aguas correspondientes al origen del manantial, a una de las bañeras y a la fuente que se encuentra en uno de los patios. Las aguas surgen a una temperatura de 48ºC; su pH es cercano a 8. El residuo seco, a 180ºC, es superior a 600 mg/L. La dureza es cercana a 500 mg/L de CaCO3, y predomina el calcio, cuyo contenido es ligeramente superior a 100 mg/L. De los aniones, bicarbonatos y sulfatos son mayoritarios; el contenido de estos últimos, ligeramente superior a los 200 mg/L, permite considerar estas aguas como sulfatadas. Los fluoruros se encuentran en cantidad ligeramente superior a 1 mg/L, lo que indica que se pueden considerar fluoradas. Los análisis realizados nos indican que se trata de aguas hipertermales, de mineralización media, muy duras, sulfatadas y fluoradas

Solubility of the metal precursor Ni(NO3)2⋅6H2O in high-pressure CO2 + ethanol mixtures

The solubility of Ni(NO3)2⋅6H2O in high-pressure CO2 + ethanol mixtures was measured using a high-pressure variable-volume view cell from (308.2 to 353.2 K) and up to 25.0 MPa. This compound has been used previously as a Ni precursor in metal deposition experiments using supercritical CO2. Ni(NO3)2•6H2O was not soluble in pure CO2 but the addition of ethanol into the system allowed the solubilisation of the hydrated salt in the mixture. Mole fraction of Ni(NO3)2•6H2O varied from 1.67 10-4 to 1.97 10-3. At these salt concentrations, the phase diagram of the CO2 + EtOH + Ni(NO3)2⋅6H2O system resembled that of the CO2 + EtOH binary system and, at the studied conditions, a vapourliquid equilibrium was observed. For the higher ethanol concentrations, the bubble points closely matched those of the CO2 + EtOH system. For the lower EtOH concentrations, however, much higher solubilisation pressures were required, due to the release of water molecules from the salt into the solution. Ni(NO3)2⋅6H2O solutions were stable in highpressure CO2 + EtOH mixtures at the studied conditions