Serum levels of the novel adipokine isthmin‑1 are associated with obesity in pubertal boys

Objectives To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin- 1 (ISM1) and obesity-related phenotypes in a population of Spanish children and to investigate the plausible molecular alterations behind the alteration of the serum levels of this protein in children with obesity. Methods The study population is a sub-cohort of the PUBMEP research project, consisting of a cross-sectional population of 119 pubertal children with overweight (17 boys, 19 girls), obesity (20 boys, 25 girls), and normal weight (17 boys, 21 girls). All subjects were classified into experimental groups according to their sex, obesity, and insulin resistance (IR) status. They were counted anthropometry, glucose and lipid metabolism, inflammation and cardiovascular biomarkers as well as isthmin-1 (ISM1) serum levels. This population was intended as a discovery population to elucidate the relationship between obesity and ISM1 levels in children. Furthermore, the study population had blood whole-genome DNA methylation examined, allowing deepening into the obesity–ISM1 molecular relationship. Results Higher serum ISM1 levels were observed in boys with obesity than in normal weight (P = 0.004) and overweight (P = 0.007) boys. ISM1 serum levels were positively associated with body mass index (BMI) Z-score (P = 0.005) and fat mass (P = 0.058) and negatively associated with myeloperoxidase (MPO) (P = 0.043) in boys. Although we did not find associations between ISM1 serum levels and metabolic outcomes in girls, which may indicate a putative sexual dimorphism, fat mass was positively associated in all children, including boys and girls (P = 0.011). DNA methylation levels in two-enhancer-related CpG sites of ISM1 (cg03304641 and cg14269097) were associated with serum levels of ISM1 in children. Conclusions ISM1 is associated with obesity in boys at the pubertal stage, elucidating how this protein might be of special relevance as a new biomarker of obesity in children. Further studies including a longitudinal design during puberty are needed.Universidad de Granada/CBUAPlan Nacional de Investigacion Cientifica, Desarrollo e Innovacion Tecnologica (I + D + I), Instituto de Salud Carlos III-Health Research Funding (FONDOS FEDER) PI051968 PI1102042 PI1600871Redes tematicas de Investigacion cooperativa RETIC Red SAMID RD12/0026/0015Mapfre Foundatio

Versión abreviada del manual de valoración del riesgo de violencia sexual (SVR-20)

Curso de Especial Interés : Victimología y CriminologíaSe realizó una abreviación del Manual de Valoración del Riesgo de Violencia Sexual, enfocado a ser un producto de fácil acceso, útil, practico y económico que permita apoyar al personal penitenciario y profesional del INPEC en la evaluación de riesgo de reincidencia en personas que se encuentran privadas de la libertad, esto con la ayuda de un estudio de mercado.Resumen 1. Justificación 2. Marco teórico 3. Marco legal 4. Marco ético 5. Objetivos del trabajo 6. Estudio de mercadeo 7. Resultados Discusión Referencias ApéndicesPregradoPsicólog

Las nuevas tecnologías entre nuestros mayores. el caso de la Universidad de Burgos

Nos encontramos en la actualidad ante nuevos campos de estudio que las Nuevas Tecnologías nos abren a todos. Uno de esos campos es el colectivo de las Personas Mayores que se encuentran ante un nuevo reto que les acecha y al que deben acostumbrarse lo antes posible si no quieren ser un nuevo modelo de analfabetos, los digitales, por lo que para saber esa relación necesitamos saber con diferentes técnicas ese grado y poder diseñar programas especiales que repercutan de manera positiva en la mejora entre la relación NNTT-Personas Mayores. Con el presente trabajo de investigación pretendemos dar a conocer en que grado las personas mayores asistentes al Programa Interuniversitario de la Experiencia y de la Universidad Abierta hacen uso de las Nuevas Tecnologías y qué opinan sobre las mismas. Además se comparará con los datos que otras instituciones tienen con respecto a este colectivo y las NNTT.We are now facing with new fields of study that New Technologies are opening to us and everybody. One of those fields is the group of the elderly people who are facing new challenges that threatens them and to be used as soon as possible if you do not want to be a new model of illiterate, digital in that case, so we need to know the relationship and the degree with different techniques to design special programs that impact positively on the improvement between the ICT-related Seniors

Formación universitaria para mayores: innovación curricular y competencias emprendedoras

Las universidades a través de la oferta de programas de formación específicos para personas mayores contribuyen al desarrollo de acciones encaminadas al envejecimiento activo a través de actividades enmarcadas dentro del ocio serio que propician la actualización de conocimientos y el desarrollo de la ciudadanía activa. A nivel europeo y dentro del desarrollo de acciones para el emprendimiento, el colectivo de personas mayores cobra relevancia como grupo de interés en las propuestas de competencias relacionadas con la creación de empresa. La presente comunicación muestra los resultados obtenidos en la fase exploratoria del proyecto de investigación sobre el desarrollo de competencias emprendedoras referidas a las motivaciones y limitaciones percibidas por los mayores universitarios para la creación de empresa.By offering specific training programs for young people universities contribute to the development of measures to promote active aging through activities framed within serious leisure time which update knowledge and develop an active citizenship. At European level and within the development of entrepreneurial actions, the group of older people becomes relevant as a stakeholder in the proposed competencies related to business creation. The present paper describes the results of the exploratory phase of a research project on the development of entrepreneurial competences regarding the motivations and constraints perceived by the life-long university students for business creation

The Socio-educational, Psychological and Family-Related Antecedents of Entrepreneurial Intentions among Spanish Youth

Despite the abundant scientific literature on entrepreneurship, there is still only limited information on young students’ entrepreneurial intentions. The reasons for this, may be generally found in the different conceptual approaches to entrepreneurial intention, and particularly in the variables that regulate and act as antecedents to such intentions. This bias has generated different lines of investigation into the factors relating to entrepreneurial intention among students. One line of investigation is centered on the variables that influence entrepreneurial intention, in particular, relational, educational, and psychological variables, and another is centered on the antecedents of entrepreneurial intention, amongst which is entrepreneurial interest. In this paper, we seek to analyze the relationship between the entrepreneurial interest of Spanish youth and a set of socio-educational, psychological, and health-related variables using principal component analysis. A previously validated ad hoc questionnaire was administered to 1764 students (15–18 years old). Notably, few Spanish youth expressed significantly high entrepreneurial interest; those who did were mostly men with a family tradition of entrepreneurial parents, who held high perceptions of their health and quality of life, and considered it important in business to detect opportunities beforehand and to create employment. Their principal motives were to improve their professional development, to put their ideas into practice, and to achieve economic independence. This paper proposes the early detection of entrepreneurial interests in young people in order to reinforce these interests as potential long-term initiatives.This research was funded by MINISTRY OF ECONOMY AND COMPETITIVENESS. GOVERNMENT OF SPAIN, grant number EDU 2012-39080-C07-00 a 07

Entrepreneurial Interest and Entrepreneurial Competence Among Spanish Youth: An Analysis with Artificial Neural Networks

Studies of the socio-economic function of entrepreneurship have emphasized the critical role that entrepreneurial competence and its implementation play at different stages of the education system. In this paper, as a research objective, we seek to determine the entrepreneurial interest of Spanish youth aged between 15 and 18 years of age enrolled in formal secondary education programs, an initial stage in the development of entrepreneurship. A previously validated ad hoc questionnaire is applied through simple random sampling to 1764 students at secondary school in Spain. A descriptive cross-sectional study is carried out. The analysis is done with Artificial Neural Networks (ANNs), a technique that reduces the high dimensionality of data through Cooperative Maximum Likelihood Hebbian Learning (CMLHL), applying neurocomputational methods to the educational sciences. We find as key results that Spanish youth express a medium level of interest in entrepreneurship. Analysis with ANNs shows that education in entrepreneurial competence is an influential aspect of interest in entrepreneurship. As a conclusion, our results suggest that educational and curricular reforms must be undertaken to promote the development of entrepreneurial competence at various stages of education in order to increase interest in entrepreneurship.This research was funded by MINISTRY OF ECONOMY AND COMPETITIVENESS. GOVERNMENT OF SPAIN, grant number EDU 2012-39080-C07-00 a 07

Entrepreneurship and leisure in the initial training of Primary Education teachers

Nuestra investigación se centra en la educación formal, como garante de la adquisición de la nueva configuración competencial que permite un desarrollo social e individual satisfactorio. Dentro de ella, el docente es el factor intraescolar de mayor impacto en el rendimiento, por lo que su desempeño profesional ha de estar acorde a los retos planteados. Así, si consideramos la competencia emprendedora y la educación para el ocio como aspectos relevantes en la configuración del modelo de ciudadanía participativa, han de verse reflejados en los procesos de formación inicial del docente, como responsable de su posterior desarrollo en la población.This paper focuses on formal education, as guarantor of the acquisition of the new competence configuration that allows a satisfactory social and individual development. Within it, the teacher is the intra-school factor with the greatest impact on performance, so that his or her professional performance must be in line with the challenges posed. Thus, considering entrepreneurship and leisure education as relevant aspects in shaping the model of participatory citizenship, they must be reflected in the processes of initial teacher training, as responsible for their subsequent development in the population

The Association of Parental Interest in Entrepreneurship with the Entrepreneurial Interest of Spanish Youth

As entrepreneurial interest is believed to represent a causal factor increasing entrepreneurship, research has begun to explore how family systems affect youth entrepreneurial interests. In the present study, we attempt to identify different types of family influence on the entrepreneurial interests of young people. A questionnaire was used to obtain data from 1633 Spanish adolescents (15 to 18 years old) and another questionnaire was used to obtain data from 839 parents. Principal component analysis identified unique family types and revealed that they have differential associations to entrepreneurial interest among youth. These findings reaffirm the influence of family on the entrepreneurial ecosystem and the promotion of an entrepreneurial family culture. This study further suggests that early attention should focus on the detection of entrepreneurial interest among youth so that actions can be implemented in the families to incentivize an entrepreneurial family culture.This research was funded by the Ministry of Economy and Competitiveness. Government of Spain. Grant Number: EDU 2012-39080-C07-00 a 07

Identificación, detección y diagnóstico de estilos de aprendizaje en el alumnado del Grado de Pedagogía

Ponencia presentada en: VI Jornadas de Innovación Docente de la UBU, Burgos, 23 y 24 de febrero de 2012, organizadas por el Instituto de Formación e Innovación Educativa-IFIE de la Universidad de Burgo

Desarrollo organizacional de las empresas mexicanas ante el covid-19: estrategias y acciones operativas

This work is characterized by determining the current Mexican companies conditions in face of the pandemic generated by COVID-19. The objective is to detect the strategies and operational actions that companies use to promote organizational development, based on the hypothesis that al least 80% of Mexican companies do so optimally. An exploratory study was developed, due to the fact that it’s a topic insufficiently studied, but at the same time novel and current issue. Likewise, descriptive, because it’s intended to specify the characteristics of Mexican companies in times of COVID-19. To obtain information and data analysis, the Survey about the Economic Impact Generated by COVID-19 in Companies (INEGI, 2020) was used, which aims to obtain information on the effects of the contingency caused by COVID-19 in Mexican companies. It was concluded that Mexican companies carry out pertinent health actions, however, they must promote operational strategies to face the pandemic, because there are 40% of companies that don’t implement any operational action.El presente trabajo, se caracteriza por determinar las condiciones actuales de las empresas mexicanas ante la pandemia generada por el COVID-19. El objetivo es detectar las estrategias y acciones operativas que emplean las empresas para impulsar el desarrollo organizacional, partiendo de la hipótesis, de que al menos el 80% de las empresas mexicanas, lo hace de forma óptima. Se desarrolló un estudio exploratorio, debido a que es un tema poco estudiado, pero a su vez novedoso y de actualidad; así mismo, descriptivo, porque se pretende especificar las características de las empresas mexicanas en tiempos del COVID-19. Para la obtención de información y análisis de datos, se empleó la Encuesta sobre el Impacto Económico Generado por COVID-19 en las Empresas (INEGI, 2020), que tiene como finalidad obtener información sobre las afectaciones de la contingencia originada por el COVID-19 en las empresas de México. Se concluyó que las empresas mexicanas, realizan acciones sanitarias pertinentes, sin embargo, deben impulsar estrategias operativas para hacer frente a la pandemia, ya que hay un 40% de empresas que no instrumentan alguna acción operativa