Development of scalable and versatile nanomaterial libraries for nanosafety studies: polyvinylpyrrolidone (PVP) capped metal oxide nanoparticles

The potential long-term environmental impact of manufactured nanomaterials (NMs) remains poorly understood, and the need to better predict NM fate and transformations and chronic effects is particularly urgent. Compared to their bulk counterparts, manufactured NMs can have distinct physical and chemical characteristics, which influence their behaviour, stability and toxicity. It is therefore essential to develop standard and reference NM libraries for environmental nanoscience and nano(eco)toxicology, and to facilitate a move towards computational prediction of NM fate, through quantitative structure–activity relationships for example. The aim of this work was to develop and fully characterise one such library, which included comparable NMs with a range of core chemistries, but the same capping agent and size range, for use in future studies to test the hypothesis that the core chemistry is a primary factor in controlling toxicity. The library contained the following NMs: 10k, 40k and 360k PVP capped ceria, zinc oxide and copper oxide (9 NMs in total). The work presented here upholds the underpinning hypothesis that the mechanism of NM formation is the same in all cases, suggesting that the protocol is very robust and has the potential to generate a wide range of comparable metal oxide NMs and potentially expand the library further with doped metal oxide and metal NMs. Characterisation by means of DLS (both size and zeta measurements), UV/Vis, XPS, FT-IR, TEM, STEM, EDX and EELS confirms that the tested synthesis protocol can easily and successfully be used to create stable PVP capped metal oxide NMs of reproducible sizes

Numerical analysis of a water wave model with a nonlocal viscous dispersive term using the diffusive approach

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Nonlinear Dynamical analysis of an AFM tapping mode microcantilever beam

We focus in this paper on the modeling and dynamical analysis of a tapping mode atomic force microscopy (AFM) microcantilever beam. This latter is subjected to a harmonic excitation of its base displacement and to Van der Waals and DMT contact forces at its free end. For AFM design purposes, we derive a mathematical model for accurate description of the AFM microbeam dynamics. We solve the resulting equations of motions and associated boundary conditions using the Galerkin method. We find that using one-mode approximation in tapping mode operating in the neighborhood of the contact region one-mode approximation may lead to erroneous results

Peer coordination through distributed triggers

This is a demonstration of data coordination in a peer data management system through the employment of distributed triggers. The latter express in a declarative manner individual security and consistency requirements of peers, that cannot be ensured by default in the P2P environment. Peers achieve to handle in a transparent way data changes that come from local and remote actions and events. The distributed triggers are implemented as an extension of the active functionality of a centralized commercial DBMS. The language and execution semantics of distributed triggers are integrated in the kernel of the DBMS such that the latter handles transparently and simultaneously both centralized and distributed triggers. Moreover, the management of distributed triggers is associated with a set of peer acquaintance and termination protocols which are incorporated in the centralized DBMS