Tumeurs rares de l’ovaire: à propos d’une série de 11 cas de tumeurs non épithéliales malignes de l’ovaire

Les tumeurs non épithéliales malignes de l'ovaire représentent environ 20% des cancers de l'ovaire. L'objectif de notre travail est de dresser lesparticularités diagnostiques cliniques et d'imagerie de ces tumeurs. Nous avons procédé à une étude rétrospective portant sur 11 cas de tumeursnon épithéliales de l'ovaire. Ces tumeurs ont été colligées au service de gynécologie et obstétrique I du CHU Hassan II de Fès sur une période de 4 ans, entre janvier 2009 et décembre 2012. Les tumeurs germinales représentant 54% (6 patientes) des cas alors que les tumeurs du cordonsexuel ont été représentées par 4 cas de tumeurs de granulosa de type adulte et nous avons colligés un cas de lymphome ovarien primitif. Lasymptomatologie clinique était dominée par la distension abdominale associée souvent à des douleurs abdominopelviennes chroniques. La tailletumorale moyenne était de 175 mm avec un aspect solido-kystique dans 54% des cas. Le dosage des marqueurs tumoraux (hormone chorioniquegonadotrope, lactate déshydrogénase, CA 125, alpha-foetoprotéine) a été réalisé chez toutes les patientes. La découverte d'une masse annexiellesuspecte chez une jeune femme doit, outre une tumeur frontière ou un cancer épithélial de l'ovaire, évoquer une tumeur non épithéliale, a fortiorisi cette masse est volumineuse, si elle est associée à des signes d'hyperestrogénie ou d'androgénie

Ab initio and Effective field Study of V doped TiO2

Using the effective field theory (EFT), the Curie temperature of V- doped rutile TiO2 has been determined. The exchange coupling used in the calculation has been deduced from first principal calculation based on the density functional theory with the local spin density approximation (LSDA). We also showed that V- doped rutile TiO2 is half metallic and the hybridization is between the V 3d states and the nearest-neighbouring O 2p states. The results from ab initio calculation showed that for weak holes concentrations the ferromagnetism is due to the double exchange, while, for higher hole concentration it comes from the RKKY exchange interaction. In addition, we show via effective field theory calculations that the transition from the nonmagnetic (NM) to the ferromagnetic (FM) phase is marked by the magnetic percolation. Magnetization as a function of the temperature for different values of the hole concentration, nc, is also given

Correspondance: A Rare Case of a Giant Pelvic Retroperitoneal Epidermoid Cyst

No abstrac

Effect of Ripening Degree of Argane Fruit on the Phenolic Composition and Antioxidant Activity of the fruit Pulp, Kernel and Oil

The quality of the vegetal oil depends to the quality of the fruit used during the extraction. Ripening of the fruit is one of the most important processes associated with metabolic changes in the fruit. These changes include variations in the fatty acid profile, fluctuations in the level of phenolic compounds. In the present study, we investigated the effect of ripening on the characteristics of Argane fruits including the variation of total phenol and flavonoid present in the pulp of the fruit, the kernel and the oil as well as their antioxidant potential. The rate of total phenol and flavonoid increases upon ripeness process in fruit parts and its oil; however, it decreases again in latest stages of ripeness. When compared to kernel extract and fruit pulp, oil extract with a ripeness index of 2.07 displays the highest inhibition of 2.2-diphenyl-1-picrylhydrazyl (DPPH). Moreover, it was revealed that the oil and kernel extract gave higher reducing power measured with the FRAP assay, It increases along the ripping process starting from ripeness index (RI) = 2.34 till 3.17.These results can be considered for a better use of fruit pulp press-cakes and oil as nutraceuticals or cosmetics. The study also helps to determine the best harvesting time in order to get a oil a high quality rich in phenolic compounds, and a large antioxidant potential which seems to be at ripeness index higher than 2.07 and lower than 3.0

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices

Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment. Study Design Feasibility study. Setting Tertiary referral center. Subjects and Methods Thirty-five patients with HNSCC were recruited, and liver tissue from 5 Wistar rats was obtained. A microfluidic device was used to maintain the tissue biopsy samples in a viable state. Rat liver was used to optimize the methodology. HNSCC was obtained from patients with T1-T3 laryngeal or oropharyngeal SCC; N1-N2 metastatic cervical lymph nodes were also obtained. Irradiation consisted of single doses of between 2 Gy and 40 Gy and a fractionated course of 5×2 Gy. Cell death was assessed in the tissue effluent using the soluble markers lactate dehydrogenase (LDH) and cytochrome c and in the tissue by immunohistochemical detection of cleaved cytokeratin18 (M30 antibody). Results A significant surge in LDH release was demonstrated in the rat liver after a single dose of 20 Gy; in HNSCC, it was seen after 40 Gy compared with the control. There was no significant difference in cytochrome c release after 5 Gy or 10 Gy. M30 demonstrated a dose-dependent increase in apoptotic index for a given increase in single-dose radiotherapy. There was a significant increase in apoptotic index between 1×2 Gy and 5×2 Gy. Conclusion M30 is a superior method compared with soluble markers in detecting low-dose radiation-induced cell death. This microfluidic technique can be used to assess radiation-induced cell death in HNSCC and therefore has the potential to be used to predict radiation response

The Minimal Supersymmetric Standard Model: Group Summary Report

CONTENTS: 1. Synopsis, 2. The MSSM Spectrum, 3. The Physical Parameters, 4. Higgs Boson Production and Decays, 5. SUSY Particle Production and Decays, 6. Experimental Bounds on SUSY Particle Masses, 7. References.Comment: 121 pages, latex + epsfig, graphicx, axodraw, Report of the MSSM working group for the Workshop "GDR-Supersym\'etrie",France. Rep. PM/98-4

Direct Observation of Longitudinally Polarised W Bosons

The three different helicity states of W bosons, produced in the reaction e+e- -> W+W- -> l nu q q~ are studied using leptonic and hadronic W decays at sqrt{s}=183GeV and 189GeV. The W polarisation is also measured as a function of the scattering angle between the W- and the direction of the e- beam. The analysis demonstrates that W bosons are produced with all three helicities, the longitudinal and the two transverse states. Combining the results from the two center-of-mass energies and with leptonic and hadronic W decays, the fraction of longitudinally polarised W bosons is measured to be 0.261 +/- 0.051(stat.) +/- 0.016(syst.) in agreement with the expectation from the Standard Model

Formation of the ηc\eta_c in Two-Photon Collisions at LEP

The two-photon width $\Gamma_{\gamma\gamma}$ of the $\eta_c$ meson has been measured with the L3 detector at LEP. The $\eta_c$ is studied in the decay modes $\pi^+\pi^-\pi^+\pi^-$, $\pi^+\pi^-$K$^+$K$^-$, K$_s^0$K$^\pm\pi^\mp$, K$^+$K$^-\pi^{0}$, $\pi^+\pi^-\eta$, $\pi^+\pi^-\eta'$, and $\rho^+\rho^-$ using an integrated luminosity of 140 pb$^{-1}$ at $\sqrt{s} \simeq 91$ GeV and of 52 pb$^{-1}$ at $\sqrt{s} \simeq 183$ GeV. The result is $\Gamma_{\gamma\gamma}(\eta_c) = 6.9 \pm 1.7 (stat.) \pm 0.8 (sys.) \pm 2.0$(BR) keV. The $Q^2$ dependence of the $\eta_c$ cross section is studied for $Q^2 < 9$ GeV$^{2}$. It is found to be better described by a Vector Meson Dominance model form factor with a J-pole than with a $\rho$-pole. In addition, a signal of $29 \pm 11$ events is observed at the $\chi_c0$ mass. Upper limits for the two-photon widths of the $\chi_c0$, $\chi_c2$, and $\eta_c'$ are also given