The Christian Academic Librarian in the Technological Society

In our contemporary society, technologies establish the course of our lives. Libraries have always engaged various technologies to bring order to disorder and over the last two decades, academic libraries have undergone significant technological change. Librarians have sought to convey an orderliness to the visible world and humanity’s body of knowledge. How this technology and body of knowledge is engaged bears significance. The engagement of the Christian academic librarian should include a distinctly Christian perspective. This paper examines the engagement of the Christian academic librarian in the technological society

Oviposition ecology and species composition of Aedes spp. and Aedes aegypti dynamics in variously urbanized settings in arbovirus foci in southeastern Côte d'Ivoire

Background Aedes mosquito-transmitted outbreaks of dengue and yellow fever have been reported from rural and urban parts of Côte d’Ivoire. The present study aimed at assessing Aedes spp. oviposition ecology in variously urbanized settings within arbovirus foci in southeastern Côte d’Ivoire. Methods Aedes spp. eggs were sampled using a standard ovitrap method from January 2013 to April 2014 in different ecosystems of rural, suburban and urban areas. Emerged larvae were reared until the adult stage for species identification. Results Aedes spp. oviposition ecology significantly varied from rural-to-urban areas and according to the ecozones and the seasons. Species richness of Aedes spp. gradually decreased from rural (eight species) to suburban (three species) and urban (one species) areas. Conversely, emerged adult Aedes spp. mean numbers were higher in the urban (1.97 Aedes/ovitrap/week), followed by the suburban (1.44 Aedes/ovitrap/week) and rural (0.89 Aedes/ovitrap/week) areas. Aedes aegypti was the only species in the urban setting (100 %), and was also the predominant species in suburban (85.5 %) and rural (63.3 %) areas. The highest Ae. aegypti mean number was observed in the urban (1.97 Ae. aegypti/ovitrap/week), followed by the suburban (1.20 Ae. aegypti/ovitrap/week) and rural (0.57 Ae. aegypti/ovitrap/week) areas. Aedes africanus (9.4 %), Ae. dendrophilus (8.0 %), Ae. metallicus (1.3 %) in the rural, and Ae. vittatus (6.5 %) and Ae. metallicus (1.2 %) in the suburban areas each represented more than 1 % of the total Aedes fauna. In all areas, Aedes species richness and abundance were higher in the peridomestic zones and during the rainy season, with stronger variations in species richness in the rural and in abundance in the urban areas. Besides, the highest Culex quinquefasciatus abundance was found in the urban areas, while Eretmapodites chrysogaster was restricted to the rural areas. Conclusions Urbanization correlates with a substantially higher abundance in Aedes mosquitoes and a regression of the Aedes wild species towards a unique presence of Ae. aegypti in urban areas. Aedes wild species serve as bridge vectors of arboviruses in rural areas, while Ae. aegypti amplifies arbovirus transmission in urban areas. Our results have important ramifications for dengue and yellow fever vector control and surveillance strategies in arbovirus foci in southeastern Côte d’Ivoire

DISTRIBUTED BROKERAGE OFFICES THROUGH INFORMATION TECHNOLOGY

This paper describes some novel ways in which Edward D. Jones and Co., a successful brokerage firm with 1650 offices nationwide, uses information technology to pursue a unique market niche: single-broker offices in communities too small to support a traditional, typically much larger, brokerage branch office. The paper focuses on the use of mainframes with "dumb" CRT terminals, rather than workstations or personal computers, to coordinate distributed operational work on a day-to-day basis.Information Systems Working Papers Serie

How Should Research And Monitoring Be Integrated?

Scientific knowledge of Chesapeake Bay and tidal tributaries has accumulated over many years beginning mostly with descriptive surveys prior to the 1960\u27s and 1970\u27s and evolving towards a coupling of monitoring and research in recent years. This essay discusses the need to more fully couple monitoring and research efforts in the Bay system because such a union of efforts is argued to be the most effective way to assess gross trends in the health of the system (monitoring) and to understand the basic forces causing these trends (research). We argue that together they provide part of the framework necessary for effective management of the living resources of the bay region.https://scholarworks.wm.edu/vimsbooks/1176/thumbnail.jp

Health, environmental change and adaptive capacity; mapping, examining and anticipating future risks of water-related vector-borne diseases in eastern Africa

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The Concept of Tectonic Provenance: Case Study of the Gigantic Markagunt Gravity Slide Basal Layer

Formation and evolution of the basal layer in large landslides has important implications for processes that reduce frictional resistance to sliding. In this report, we show that zircon geochronology and tectonic provenance can be used to investigate the basal layer of the gigantic-scale Markagunt gravity slide of Utah, USA. Basal layer and clastic injectite samples have unique tectonic chronofacies that identify the rock units that were broken down during emplacement. Our results show that basal material from sites on the former land surface is statistically indistinguishable and formed primarily by the breakdown of upper plate lithologies during sliding. Decapitated injectites have a different tectonic chronofacies than the local basal layer, with more abundant lower plate-derived zircons. This suggests clastic dikes formed earlier in the translation history from a structurally deeper portion of the slide surface and a compositionally different basal layer before being translated to their current position

Structural Relationships Across the Sevier Gravity Slide of Southwest Utah and Implications for Catastrophic Translation and Emplacement Processes of Long Runout Landslides

The physical processes that facilitate long-distance translation of large-volume gravity slides remain poorly understood. To better understand these processes and the controls on runout distance, we conducted an outcrop and microstructural characterization of the Sevier gravity slide across the former land surface and summarize findings of four key sites. The Sevier gravity slide is the oldest of three mega-scale (\u3e1,000 km2) collapse events of the Marysvale volcanic field (Utah, USA). Field observations of intense deformation, clastic dikes, pseudotachylyte, and consistency of kinematic indicators support the interpretation of rapid emplacement during a single event. Furthermore, clastic dikes and characteristics of the slip zone suggest emplacement involved mobilization and pressurized injection of basal material. Across the runout distance, we observe evidence for progressive slip delocalization along the slide base. This manifests as centimeter- to decimeter-thick cataclastic basal zones and abundant clastic dikes in the north and tens of meters thick basal zones characterized by widespread deformation of both slide blocks and underlying rock near the southern distal end of the gravity slide. Superimposed on this transition are variations in basal zone characteristics and slide geometry arising from interactions between slide blocks during dynamic wear and deposition processes and pre-existing topography of the former land surface. These observations are synthesized into a conceptual model in which the presence of highly pressurized fluids reduced the frictional resistance to sliding during the emplacement of the Sevier gravity slide, and basal zone evolution controlled the effectiveness of dynamic weakening mechanisms across the former land surface

Cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in Alzheimer's disease

INTRODUCTION: In Alzheimer's disease (AD), hyperphosphorylated tau is closely associated with focal neurodegeneration, but the mechanism remains uncertain. METHODS: We quantified cortical microstructure using neurite orientation dispersion and density imaging in 14 individuals with young onset AD. Diffusion tensor imaging measured mean diffusivity (MD). Amyloid beta and tau positron emission tomography were acquired and associations with microstructural measures were assessed. RESULTS: When regional volume was adjusted for, in the medial temporal lobe there was a significant negative association between neurite density and tau (partial R2  = 0.56, p = 0.008) and between orientation dispersion and tau (partial R2  = 0.66, p = 0.002), but not between MD and tau. In a wider cortical composite, there was an association between orientation dispersion and tau (partial R2  = 0.43, p = 0.030), but not between other measures and tau. DISCUSSION: Our findings are consistent with tau causing first dendritic pruning (reducing dispersion/complexity) followed by neuronal loss. Advanced magnetic resonance imaging (MRI) microstructural measures have the potential to provide information relating to underlying tau deposition

Predicting Cognitive Decline in Nondemented Elders Using Baseline Metrics of AD Pathologies, Cerebrovascular Disease, and Neurodegeneration

BACKGROUND AND OBJECTIVES: Dementia is a growing socio-economic challenge that requires early intervention. Identifying biomarkers that reliably predict clinical progression early in the disease process would better aid selection of individuals for future trial participation. Here we compared the ability of baseline, single time-point biomarkers (CSF amyloid 1-42, CSF ptau-181, white matter hyperintensities (WMH), cerebral microbleeds (CMB), whole-brain volume, and hippocampal volume) to predict decline in cognitively normal individuals who later converted to mild cognitive impairment (MCI) (CNtoMCI), and those with MCI who later converted to an Alzheimer's disease (AD) diagnosis (MCItoAD). METHODS: Standardised baseline biomarker data from ADNI2/Go, and longitudinal diagnostic data (including ADNI3), were used. Cox regression models assessed biomarkers in relation to time to change in clinical diagnosis using all follow-up timepoints available. Models were fit for biomarkers univariately, and together in a multivariable model. Hazard Ratios (HR) were compared to evaluate biomarkers. Analyses were performed separately in CNtoMCI and MCItoAD groups. RESULTS: For CNtoMCI (n = 189), there was strong evidence that higher WMH volume (individual model: HR 1.79, p = .002; fully-adjusted model: HR 1.98, p = .003), and lower hippocampal volume (individual: HR 0.54, p = .001; fully-adjusted: HR 0.40, p < .001) were associated with conversion to MCI individually and independently. For MCItoAD (n = 345), lower hippocampal (individual model: HR 0.45, p < .001; fully-adjusted model: HR 0.55, p < .001) and whole-brain volume (individual: HR 0.31, p < .001; fully-adjusted: HR 0.48, p = .02), increased CSF ptau (individual: HR 1.88, p < .001; fully-adjusted: HR 1.61, p < .001), and lower CSF amyloid (individual: HR 0.37, p < .001, fully-adjusted: HR 0.62, p = .008) were most strongly associated with conversion to AD individually and independently. DISCUSSION: Lower hippocampal volume was a consistent predictor of clinical conversion to MCI and AD. CSF and brain volume biomarkers were predictive of conversion to AD from MCI, while WMH were predictive of conversion to MCI from cognitively normal. The predictive ability of WMH in the CNtoMCI group may be interpreted as some being on a different pathological pathway, such as vascular cognitive impairment

Vestibular Stimulation for ADHD: Randomized Controlled Trial of Comprehensive Motion Apparatus

Objective: This research evaluates effects of vestibular stimulation by Comprehensive Motion Apparatus (CMA) in ADHD. Method: Children ages 6 to 12 (48 boys, 5 girls) with ADHD were randomized to thrice-weekly 30-min treatments for 12 weeks with CMA, stimulating otoliths and semicircular canals, or a single-blind control of equal duration and intensity, each treatment followed by a 20-min typing tutorial. Results: In intent-to-treat analysis (n = 50), primary outcome improved significantly in both groups (p = .0001, d = 1.09 to 1.30), but treatment difference not significant (p = .7). Control children regressed by follow-up (difference p = .034, d = 0.65), but overall difference was not significant (p = .13, d = .47). No measure showed significant treatment differences at treatment end, but one did at follow-up. Children with IQ-achievement discrepancy ≥ 1 SD showed significantly more CMA advantage on three measures. Conclusion: This study illustrates the importance of a credible control condition of equal duration and intensity in trials of novel treatments. CMA treatment cannot be recommended for combined-type ADHD without learning disorder