23 research outputs found

    Lymphome CĂ©rĂ©bral Primitif (LCP) du Sujet ImmunocompĂ©tent: A Propos d’Un cas Ă  l’HĂŽpital National de Niamey (HNN)

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    Le Lymphome CĂ©rĂ©bral Primitif (LCP) du sujet immunocompĂ©tent est une entitĂ© rare des lymphomes Non Hodgkiniens en gĂ©nĂ©ral et des tumeurs cĂ©rĂ©brales en particulier. Il est caractĂ©risĂ© par sa sĂ©vĂ©ritĂ© clinique, mais aussi son mauvais pronostic. Nous rapportons un cas de LCP chez un sujet immunocompĂ©tent diagnostiquĂ© au service de neurologie et pris en charge au service d’Onco-hĂ©matologie de l’HĂŽpital National de Niamey.   Primary Cerebral Lymphoma (PCL) of the immunocompetent subject is a rare feature of non-Hodgkin's lymphoma in general and brain tumors in particular. It is characterized by its clinical severity, but also its poor prognosis. We report a case of LCP in an immunocompetent subject diagnosed in the neurology department and managed by Onco-hematology at the National Hospital of Niamey

    Lymphome CĂ©rĂ©bral Primitif (LCP) du Sujet ImmunocompĂ©tent: A Propos d’Un cas Ă  l’HĂŽpital National de Niamey (HNN)

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    Le Lymphome CĂ©rĂ©bral Primitif (LCP) du sujet immunocompĂ©tent est une entitĂ© rare des lymphomes Non Hodgkiniens en gĂ©nĂ©ral et des tumeurs cĂ©rĂ©brales en particulier. Il est caractĂ©risĂ© par sa sĂ©vĂ©ritĂ© clinique, mais aussi son mauvais pronostic. Nous rapportons un cas de LCP chez un sujet immunocompĂ©tent diagnostiquĂ© au service de neurologie et pris en charge au service d’Onco-hĂ©matologie de l’HĂŽpital National de Niamey.   Primary Cerebral Lymphoma (PCL) of the immunocompetent subject is a rare feature of non-Hodgkin's lymphoma in general and brain tumors in particular. It is characterized by its clinical severity, but also its poor prognosis. We report a case of LCP in an immunocompetent subject diagnosed in the neurology department and managed by Onco-hematology at the National Hospital of Niamey

    IntĂ©rĂȘt D’une Recherche De Thrombophilie Au Cours Des Thromboses De La Veine Porte Dans Un Service De MĂ©decine Interne

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    Background: Many causes of portal vein thrombosis are described and most patients had a combination of local and systemic risk factors. In many studies, prtothombotic disorders investigations were conducted in various departments of haematologies and/or gastroenterology. In this study, we investigated the systemic risk factors associated or not to abdominal inflammation in a series of patients recruited in a department of Internal Medicine. Methods: We studied, retrospectively from 2005 to 2009, 21 cases of patients with portal vein thrombosis. Patients with cancer are not included in this study. Results: We reported 21 patients with portal vein thrombosis: 8 males (43%) and 13 females (57%). The average age of patients was 46, 6 years (20; 59). Eight (8) patients had abdominal inflammatory pathology and 21 (100%) patients had systemic prothrombotic factors. This etiologic investigation is rentable because in 18 cases, abdominal inflammation and/or prothombotic disorders are diagnosed. This diagnostic, however, can permit to discuss a specific management. Conclusion: Extensive investigation of prothrombotic disorders is necessary in portal vein thrombosis, although if local abdominal inflammation exist

    Interet D’une Supplementation En Spiruline Chez Les Enfants Drepanocytaires Homozygotes A L’hopital National De Niamey. (Essai Clinique Randomise En Double Aveugle A Propos De 53 Cas)

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    Spirulina is a micro algae used for thousands of years due to its healing properties. We supplemented children suffering from sickle cell anemia in order to appreciate its impact on the anthropometrical and clinical parameters. It consisted of a randomized clinical double blind test which was carried during a period of 9 months. The study concerned 53 homozygotes children suffering from sickle cell anemia aged 6 months to 15 years. Also, they were visiting the National Hospital of Niamey for follow up. One group (28 children) received 5 g of spirulina daily, and the other group (25 children) received placebo. The aspects studied were: the number of hospitalizations and transfusions, the vaso-occlusive crisis, the body mass index, and the splenomegalia. We found that 84.90% of patients were hospitalized at least once and 45.3% of them have already been transfused. The average number of crisis has greatly decreased in the spirulina group from 2.75 before the study to 1.18 at the end of the study. This, thus, was observed when compared to 2.44 to 1.6 in the placebo group. We also noticed a decrease of the number of hospitalizations and the number of transfusions which is less important in the group supplemented with spirulina. In conclusion, this study showed that supplementation in spirulina had a significant impact on children suffering from sickle cell anemia. This is even despite the fact that the difference between the two groups is not significant in some cases

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised

    Caractérisation des saisons agricoles au Sahel : analyse des données agro-climatiques versus vécu paysan, cas de la Région de Zinder, Niger

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    Cette Ă©tude a pour objectif de caractĂ©riser les dynamiques des saisons agricoles au Sahel au cours des soixante derniĂšres annĂ©es. Elle s'est appuyĂ©e sur l'analyse des donnĂ©es agro-climatiques et des enquĂȘtes effectuĂ©es dans huit communes de la rĂ©gion de Zinder (Niger). Quelques indicateurs des saisons sont statistiquement dĂ©terminĂ©s et comparĂ©s aux savoirs et vĂ©cus des paysans. Les rĂ©sultats ont montrĂ© que le dĂ©but de saison agricole est trĂšs variable et intervient de plus en plus tardivement, contrairement Ă  la fin qui est relativement constante. La durĂ©e des saisons se raccourcit et la frĂ©quence d'occurrence des saisons 'longues' n'est que 16 % aujourd'hui, contre 75 % avant la rupture climatique de 1967. Par ailleurs, il est montrĂ© que les paysans utilisent des indicateurs atmosphĂ©riques spĂ©cifiques (comportement des vents, couleurs des nuages) et environnementaux (migration et nidification d'oiseaux, feuillaison des espĂšces vĂ©gĂ©tales, etc.) pour dĂ©finir le calendrier agricole, prĂ©dire la productivitĂ© et anticiper la mitigation des risques en cas de prĂ©sages des mauvaises rĂ©coltes. De ce fait, des approches d'adaptation fondĂ©es sur l'intĂ©gration des savoirs des paysans doivent ĂȘtre promues en vue d'une meilleure adhĂ©sion et diffusion de celles-ci en milieu communautaire

    Evolution de la conductivité hydraulique d'un sol sableux cultivé dans l'Ouest du Niger

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    Description du sujet. Ce travail prĂ©sente et analyse l'Ă©volution de la conductivitĂ© hydraulique des surfaces cultivĂ©es et en jachĂšre des formations pĂ©dologiques sablo-limoneuses couvrant les altĂ©rites du socle cristallin de l'Ouest du Niger. Le travail est menĂ© en des emplacements choisis pour leur reprĂ©sentativitĂ© dans la zone sahĂ©lienne cultivĂ©e. Objectifs. Il vise Ă  faire ressortir l'effet des pratiques culturales, sarclage humide, sarclage sec, sur cette Ă©volution et leurs consĂ©quences sur l'infiltrabilitĂ© du sol et le ruissellement. MĂ©thode. L'approche utilisĂ©e consiste Ă  Ă©tudier l'infiltration sous condition de faible succion grĂące Ă  un dispositif constituĂ© d'un infiltromĂštre et de deux minitensiomĂštres dans le cadre d'un Ă©coulement monodimensionnel. RĂ©sultats. Les mesures, effectuĂ©es en suivant le cumul de pluie reçue, ont permis de dĂ©terminer et quantifier (i) l'effet du sarclage, (ii) celui de l'humiditĂ© prĂ©alable du sol au moment du sarclage et (iii) celui de la mise en jachĂšre sur l'Ă©volution de la conductivitĂ© hydraulique. La valeur de la conductivitĂ© hydraulique en surface s'avĂšre toujours infĂ©rieure Ă  celle du sol sous-jacent. La conductivitĂ© de la jachĂšre est stable autour de 20 mm·h-1. Celle des zones cultivĂ©es, vtrĂšs Ă©levĂ©e (120 mm·h-1) aprĂšs sarclage humide retrouve la valeur mesurĂ©e en jachĂšre aprĂšs 70 mm de pluie et devient mĂȘme moitiĂ© moindre aprĂšs 230 mm de pluie. Le sarclage en conditions sĂšches est peu performant, Ă  la fois en termes de conductivitĂ© et en termes de persistance de son effet. Conclusions. On en dĂ©duit que l'effet bĂ©nĂ©fique du sarclage n'est que d'assez courte durĂ©e et l'opĂ©ration devrait ĂȘtre renouvelĂ©e aprĂšs 100 mm de pluie reçue. (RĂ©sumĂ© d'auteur

    Maladie de hodgkin a propos de 40 cas colliges a l’hopital national de Niamey (HNN) au Niger.

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    Objectifs : Cette Ă©tude vise Ă  dĂ©crire les caractĂ©ristiques Ă©pidĂ©miologiques, cliniques et paracliniques de la maladie de Hodgkin (MdH). C’est la premiĂšre Ă©tude nigĂ©rienne spĂ©cialement consacrĂ©e Ă  cette maladie.Patients et mĂ©thodes : Il s’agit de patients suivis en service d’Onco-HĂ©matologie de l’HNN pour MdH pendant une pĂ©riode de 10 ans (janvier 2000 Ă  dĂ©cembre 2009). Les donnĂ©es avaient Ă©tĂ© recueillies Ă  partir des dossiers des malades.RĂ©sultats : Quarante (40) dossiers Ă©taient retenus pour l’étude. L’ñge moyen Ă©tait de 25,4 ans et les extrĂȘmes entre 5 et 65 ans. Le sex ratio hommes/femmes Ă©tait de 3. Les adĂ©nopathies (ADP) superficielles constituaient le principal motif de consultation (97,50%). Les principales localisations des (ADP) Ă©taient cervicales (60%). Le signe clinique d’évolutivitĂ© le plus frĂ©quent Ă©tait la fiĂšvre (65%). Les stades III et IV reprĂ©sentaient 62,97% des cas. Sur le plan biologique, la cytologie mettait en Ă©vidence la cellule de Reed Sternberg dans 90% des cas et Ă  l’histologie les types 3 et 4 reprĂ©sentaient 69% des cas (respectivement 38% et 31%). L’anĂ©mie Ă©tait retrouvĂ©e dans 57% et l’hyperleucocytose dans 29% des cas. La vitesse de sĂ©dimentation accĂ©lĂ©rĂ©e dans 93,75% des cas Ă©tait le signe biologique d’évolutivitĂ© le plus frĂ©quent. La sĂ©rologie VIH Ă©tait positive dans 5,60% des cas. A l’imagerie, le scanner Ă©tait rĂ©alisĂ© chez seulement 1 patient. La radiographie pulmonaire standard avait montrĂ© des adĂ©nopathies mĂ©diastinales dans 75% des cas et l’échographie avait objectivĂ© la splĂ©nomĂ©galie et l’hĂ©patomĂ©galie respectivement dans 42,85%, et 38,09% des cas.Conclusion : La MdH est une hĂ©mopathie maligne rencontrĂ©e au Niger plus souvent chez l’homme de jeune Ăąge. La principale manifestation Ă©tait les adĂ©nopathies cervicales. Le diagnostic Ă©tait souvent rĂ©alisĂ© Ă  un stade avancĂ© de la maladie. L’extension de la maladie est sous-estimĂ©e du fait de l’insuffisance du plateau technique.Mots clĂ©s : Hodgkin, Cellule de Reed Sternberg, adĂ©nopathie, cytologie, Niamey.HODGKIN DESEASE: STUDY OF 40 CASES AT THE NATIONAL HOSPITAL OF NIAMEY IN NIGER. ABSTRACTPurpose: The study aims to describe the epidemiological, clinical, and para-clinical characteristics of Hodgkin disease (HD). It is the first kind of study conducted which especially targets this disease in Niger.Patients and method: It is about patients followed at the Onco-Hematology service of the National Hospital of Niamey. The study was spanned on 10 years from January 2000 to December 2009. The data were obtained from patient files.Results: The mean age of the patients was 25.4 years. Males predominate with a sex ratio of 3. The extremes were 5 and 65 years. Superficial adenopathies were the most frequent symptoms (97.5%). The main localizations were cervical (60%). The most frequent clinical evolution signs were fever (65%). Stages III and IV represented 62.77% of the cases. The cytological exam highlights the Reed Sternberg cell (72.5% of cases). The histological exam revealed that types 3 and 4 represented 69% of the cases. The anemia was found in 57% and the hyperleucocytosis with 29% of the cases. The speed of sedimentation was up in 93.75% of the patients. It was the main sign of biological evolution. The HIV serology was positive in 5.60% of patients. The scanner has been realized to one patient. The chest radiography showed that mediastinal adenopathies were the most frequent deep localizations (75%). The echography showed that the splenomegaly and the hepatomegaly represented respectively 42.85% and 39.09% of cases.Conclusion: The Hodgkin disease is most often found among young males in Niger. The main manifestation was cervical adenopathies. The diagnosis was often done at an advance stage of the disease. The scope of the disease was underestimated due to the shortage of technical equipment.Keywords: Hodgkin, Reed Sternberg Cell, adenopathy, cytology, Niamey

    La grosse jambe en service de medecine interne de L’hopital National de Niamey (HNN)

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    But: L’objectif Ă©tait de contribuer Ă  l’étude Ă©pidĂ©miologique et Ă©tiologique des grosses jambesMĂ©thode: Il s’agissait d’une Ă©tude rĂ©trospective et prospective sur 43 mois en service de MĂ©decine Interne de l’HĂŽpital National de Niamey (HNN).RĂ©sultats: Au total, 74 patients ont Ă©tĂ© inclus soit une frĂ©quence de 1,12%. L’ñge moyen de nos patients est de 38,68 ans et la tranche d’ñge la plus touchĂ©e est celle de 30 Ă  40 ans soit 29,7%. Les sujets de sexe fĂ©minin sont les plus touchĂ©s avec 60,8%. Les Ă©tiologies sont diverses et les principales sont reprĂ©sentĂ©es par la thrombophlĂ©bite avec 58,1% et l’envenimation par morsure de serpent avec 20,3%.Conclusion: Cette Ă©tude doit ĂȘtre poursuivi afin d’avoir des donnĂ©es de rĂ©fĂ©rence sur les Ă©tiologies de grosses jambes au Niger.Mots clĂ©s: Grosse jambe, thrombophlĂ©bite, envenimation, Ă©rysipĂšle, lymphoedĂšme, NiameyEnglish Title: The big leg in the service of internal medicine in the National Hospital of Niamey (NHN)English AbstractObjective: the aim was and to contribute to the study of the epidemiological and etiological of big legs in Internal Medicine service of Niamey National Hospital.Method: We conducted a retrospective and prospective study during 43 months in Internal Medicine service of Niamey.Results: We included 74 patients during the study period. Thus, the frequency of big leg is 1.12%. The mean age of our patients is 38.68 years old. The age portion mostly affected is 30 to 40 years old with frequency of 29.7%. The causes are various and the principals etiologies were represented by thrombophlebitis (58.1% of big legs) followed by envenimation of snake bite with 20.3% frequency. The female gender is the most affected with 60.8%.Conclusion: This study should be continued to have references of big legs etiologies in Niger.Keywords: Big leg, thrombophlebitis, envenimation, erysipelas, lymphoedema, Niame
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