Phytomedicine for Diabetes mellitus: An overview

Diabetes mellitus is a complex metabolic disorder resulting from either insulin insufficiency or insulin dysfunction. Diabetes mellitus affect most of the people of both developed and developing countries. The treatment of diabetes with synthetic drugs is costly and chances of side effects are high. Phytomedicine has been used since ancient time in many parts of the world where access to modern medicine is limited. Low-fat vegan diet has improved glycemic control in type II diabetic patients. Photochemical identified from medicinal plants presents an exciting opportunity for the development of new types of therapeutics for diabetes mellitus. Most prevalent of photochemical groups are the alkaloids, terpenes, and phenolics. Several formulations like herbal teas, extracts, decoctions, infusions, tinctures, etc are prepared from medicinal plants. Despite considerable progress in the development of synthetic drugs, the search for the invention of phytomedicine as alternative therapy is progressing

Growth of hydroxyapatite on physiologically clotted fibrin capped gold nanoparticles

The growth of hydroxyapatite (HAp) on physiologically clotted fibrin (PCF)-gold nanoparticles is presented for the first time by employing a wet precipitation method. Fourier transform infrared (FTIR) spectroscopy confirmed the characteristic functionalities of PCF and HAp in the PCF-Au-HAp nanocomposite. Scanning electron microscopy (SEM) images have shown cuboidal nanostructures having a size in the range of 70-300 nm of HAp, whereas 2-50 nm sized particles were visualized in high-resolution transmission electron microscopy (TEM). Energy-dispersive X-ray (EDX) and X-ray diffraction (XRD) studies have confirmed the presence of HAp. These results show that gold nanoparticles with PCF acted as a matrix for the growth of HAp, and that PCF-Au-HAp nanocomposite is expected to have better osteoinductive properties