519 research outputs found

    Amplifier for optimal reflection Coefficient of ultrasound transducer: A study of op amp based circuits for ultrasound transducers, targeted for low reflection Coefficient, high gain, and low noise

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    Reverberation is defined as equally-spaced, bright linear echoes resulting from reflection from specular-type interfaces. They are provoked by the acoustic Impedance change between the tissue and transducer front surface. B. Angelsen developed a mathematical approach to correct this ultrasound artifact by coupling the ultrasound transducer with an ideal electrical load in order to obtain zero reflection coefficients on the transducer from face [1]. However, when analyzing Impedance spectroscopy this approach cannot be achieved by using passive electronics in most simulated cases. Active impedance may be seen as a trend to improve image quality. This research therefore implements and simulates methods for active impedance synthesis [5] and applies Particle Swarm Optimization to the proposed electronics. Finally, the simulations are compared through a LAB experiment

    Monte Carlo study of the interfacial adsorption of the Blume-Capel model

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    We investigate the scaling of the interfacial adsorption of the two-dimensional Blume-Capel model using Monte Carlo simulations. In particular, we study the finite-size scaling behavior of the interfacial adsorption of the pure model at both its first- and second-order transition regimes, as well as at the vicinity of the tricritical point. Our analysis benefits from the currently existing quite accurate estimates of the relevant (tri)critical-point locations. In all studied cases, the numerical results verify to a level of high accuracy the expected scenarios derived from analytic free-energy scaling arguments. We also investigate the size dependence of the interfacial adsorption under the presence of quenched bond randomness at the originally first-order transition regime (disorder-induced continuous transition) and the relevant self-averaging properties of the system. For this ex-first-order regime, where strong transient effects are shown to be present, our findings support the scenario of a non-divergent scaling, similar to that found in the original second-order transition regime of the pure model.Comment: 6 pages, 5 figures, version published in Phys. Rev. E. arXiv admin note: text overlap with arXiv:1610.0822

    Interview with Maria Luisa Zamudio-Mainou, Class of 2004 and 2016

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    Oral history interview with Illinois State University alum Dr. Maria Luisa Zamudio-Mainou, Class of 2004 and 2016. The interview was conducted by Milner Library student employee Rexton Jones on July 10, 2023. In the interview Zamudio-Mainou, formerly the executive director of the National Center for Urban Education at ISU, reflects on her educational and professional journey. Born and raised in Tampico, Mexico, she pursued an undergraduate education in her hometown before transitioning to a career in banking. In 2000, she moved to Bloomington-Normal to study English at ISU, eventually shifting into the Foreign Languages department’s literature and culture graduate program. After a year at ISU, a job opened up in the College of Education’s bilingual education program and Zamudio-Mainou found herself working with some 250 Spanish-speaking teachers from across Latin America. This sparked an interest in education, eventually leading her to pursue a PhD in higher education administration at the university. In addition to the difficulty of learning English, Zamudio-Mainou also had to contend with cultural differences in the U.S. and the isolation of often being the only Latina in the room. She found a mentor in her graduate advisor and the director of the College of Education’s bilingual program, George Torres, with whom she would later collaborate on future grant projects. Zamudio-Mainou has held multiple positions during her decades-long career at ISU, including working on a grant transitioning paraprofessionals into becoming certified teachers. She also engaged in teaching multicultural education courses and coordinating study abroad programs. Zamudio-Mainou\u27s dual roles provided her with a unique perspective, allowing her to work closely with underrepresented students while navigating administrative responsibilities. Reflecting on her accomplishments, she finds pride in witnessing her students\u27 success and graduation.https://ir.library.illinoisstate.edu/aoh/1060/thumbnail.jp

    Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells

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    Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus. Here, we examined entry of CRCoV into human rectal tumor cells (HRT-18G cell line) by analyzing co-localization of single virus particles with cellular markers in the presence or absence of chemical inhibitors of pathways potentially involved in virus entry. We also targeted these pathways using siRNA. The results show that the virus hijacks caveolin-dependent endocytosis to enter cells via endocytic internalization

    Quitosán y fluoruro de sodio para la conservación sostenible de restos óseos

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    Este artículo presenta dos sustancias para la conservación de hueso que pueden utilizarse juntas o separadas, dependiendo de su composición química: fluoruro de sodio y quitosán. A diferencia de las técnicas tradicionales con polímeros sintéticos, este enfoque trata tanto la parte inorgánica (mineral) como la orgánica (colágeno). El fluoruro de sodio promueve la remineralización formando fluorapatita, lo que mejora la estabilidad; mientras que el quitosán, un biopolímero con propiedades antibacterianas, puede compensar la pérdida de colágeno, aumentando su resistencia mecánica. Su aplicación desde 1995 en la CNCPC, México, ha resultado exitosa para tratar elementos óseos históricos, arqueológicos y fósiles. Además, previene el crecimiento microbiano y es menos invasivo que otras técnicas de consolidación porque no hace capas en superficie ni rellena espacios, permitiendo la conservación sin alteración estructural. Las características de ambas sustancias las posicionan como una opción más sostenible que las opciones tradicionales de tratamiento de hueso. El estudio detalla los procedimientos de preparación, métodos de aplicación y casos de estudio que demuestran su efectividad

    CONCEPCIONES DE APRENDIZAJE QUE ORIENTAN LA CONSTRUCCIÓN DE LOS PLANES DE ESTUDIO DE LA CARRERA DE PSICOPEDAGOGÍA DE LA UFLO Y DE LA UNCO

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    The basic aim of this paper was to identify and analyze the conceptions of learning in students studying Educational Psychology at the National University of Comahue and the University of Flores at Comahue. This study was carried out at different times during their undergraduate training under the respective curricula. It employs the ideas developed before and during college, which guides the construction of various conceptions of learning

    Biologic and Molecular Properties of LMP1: CTARs, Strains, and Beyond

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    Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with the development of lymphoid and epithelial malignancies including Hodgkin lymphoma (HD), post-transplant lymphoproliferative disorder (PTLD), nasopharyngeal carcinoma (NPC), and others. Latent membrane protein 1 (LMP1) is the EBV oncogene as it is necessary for EBV-mediated transformation of B-lymphocytes and can itself transform rodent fibroblasts. LMP1 has a short amino-terminal cytoplasmic end, 6 transmembrane domains, and a long carboxyl-terminal cytoplasmic tail that contains the two signaling domains, the carboxyl-terminal activation regions 1 and 2 (CTAR1 and CTAR2). Through CTAR1 and CTAR2, LMP1 activates several signaling pathways including NF[kappa]B, phosphatidylinositol 3-kinase (PI3K), mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK) pathways. In this study, CTAR1 was shown to be necessary for Rat-1 fibroblast transformation and activation of the PI3K-Akt pathway, whereas CTAR2 was dispensable. LMP1-mediated rodent fibroblast transformation did not require I[kappa]B[alpha]-dependent activation of NF[kappa]B. Seven sequence variants of LMP1 have been identified: Alaskan, B95.8, China 1, China 2, Med+, Med-, and NC. The frequency of detection of these variants differs in various EBV-associated malignancies from different geographic regions. In this study, all the sequence variants were demonstrated to transform Rat-1 fibroblasts, induce increased motility of human foreskin keratinocytes, induce homotypic adhesion of BJAB cells and activate the PI3K-Akt signaling pathway. The Alaskan, China 1 and Med+ variants had limited binding to the E3 ubiquitin ligase component HOS and enhanced NF[kappa]B signaling. These findings indicate that the signature amino acid changes of the LMP1 variants do not hinder or significantly enhance their in vitro transforming potential or signaling properties. Finally, dominant negative forms of TRAF2 and TRAF3 inhibited LMP1-mediated transformation of rodent fibroblasts. Activation of PI3K-Akt signaling and deregulation of cell-cycle markers were mapped to the TRAF-binding site and residues between CTAR1 and CTAR2. Activation of the MEK1/2-ERK1/2 signaling pathway through the TRAF-binding site was required for LMP1-induced transformation of rodent fibroblasts. These findings identify a signaling pathway that is uniquely activated by CTAR1

    Design, construction, programming and monitoring of a testbench for brushless motors

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    This document explains how to develop successfully a testbench for brushless motors connected wireless to a PC to analyze the data. This dissertation involves all the development and implementation of all the parts of the final prototype, including workarounds and redesigns. It also includes all the technical information to reproduce such prototype and all the software and source code necessary for the toolAquest document explica com desenvolupar satisfactoriament una bancada de proves per a motors de tipo brushless connectada sense fils a un PC per al analisi de dades. Aquesta memoria inclou tot el desenvolupament i la implementació de totes les parts del prototip final, incloent tots els workarounds i redissenys. També conté tota la informació tecnica per reproduir el montatge del prototip i tot el codi font del software desenvolupat per a la eina de visualitzacióEste documento explica cómo desarrollar satisfactoriamente una bancada de pruebas para motores de tipo brushless conectada inalámbricamente a un PC para el análisis de datos. Esta memoria incluye todo el desarrollo y la implementación de todas las partes del prototipo final, incluyendo todos los workarounds y rediseños. También contiene toda la información técnica para reproducir el montaje del prototipo y todo el código fuente del software desarrollado para la herramienta de visualizació
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