7 research outputs found
Properties of the asymptotic nA+mB->C reaction-diffusion fronts
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/04/2000
- Field of study
We discuss, at the mean-field level, the asymptotic shape of the reaction
fronts in the general nA+mB->C reaction-diffusion processes with initially
separated reactants, thus generalizing to arbitrary reaction-order kinetics the
work done by Galfi and Racz for the case n=m=1. Consequences for the formation
of Liesegang patterns are discussed.Comment: EPJ-TeX, 6 pages, 2 figs included. Statement on tails' decay revised.
References added and correcte
A non-randomized pilot trial of the use of prazosin in the prevention of transition from acute stress disorder to post-traumatic stress disorder
- Publication venue
- Taylor & Francis Group
- Publication date
- 06/09/2023
- Field of study
ABSTRACTBackground: Following a traumatic event, 40–80% of the patients with acute stress disorder (ASD) will develop post-traumatic stress disorder (PTSD), 67% at 6 months. Alpha1-blockers are effective in treating some symptoms of PTSD but their usefulness in acute stress situations remains unclear. We hypothesized that reducing noradrenergic hyperactivity with an alpha1-blocker during the acute phase after a traumatic event could prevent the transition to PTSD in patients with ASD.Objective: To investigate the efficacy and safety of a 1-month course of alpha1-blocker (prazosin) to prevent the transition to PTSD in patients with ASD at 6 months.Method: In a monocentric open-label prospective pilot study, 15 patients with ASD were included within 3–7 days of exposure to a traumatic event. After enrolment, they received prazosin LP at home at bedtime at 2.5 mg/day for 7 days and then 5 mg/day for 21 days. Incidence of PTSD was assessed at 6 months using the Clinician Administrated PTSD Scale (CAPS).Results: At 6 months, 22% of patients who completed the study (2/9) met the diagnostic criteria for PTSD. This rate was significantly lower than that observed in previous studies (67%; p = .047). The treatment was well tolerated and there were no serious adverse events.Conclusions: These preliminary findings indicating the safety of prazosin and suggesting its potential to prevent the development of PTSD in ASD require to be replicated in large-scale randomized placebo-controlled studies.Trial registration: The study was pre-registered on a public database (www.clinicalTrials.gov identifier: NCT03045016)
Instantaneous and continuous cardiac output obtained with a Doppler pulmonary artery catheter
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Adult-onset genetic leukoencephalopathies: a MRI pattern-based approach in a comprehensive study of 154 patients.
- Author
- Amati-Bonneau Patrizia
- Aubourg Patrick
- Audoin Bertrand
- Ayrignac Xavier
- Bataillard Marc
- Bellesme Celine
- Berger Eric
- Blanc Frederic
- Boespflug Tanguy Odile
- Bonneau Dominique
- Brassat David
- Brochet Bruno
- Camdessanche Jean-Philippe
- Carra Dallière Clarisse
- Castelnovo Giovanni
- Chanson Jean-Baptiste
- Clanet Michel
- Clavelou Pierre
- Cohen Mickael
- Collongues Nicolas
- de Seze Jerome
- Debouverie Marc
- Deburghgraeve VĂ©ronique
- Defer Gilles Louis
- Denier Christian
- Derache Nathalie
- Devoize Jean Louis
- Dorboz Imen
- Durand-Dubief Francoise
- Edan Gilles
- Giroud Maurice
- Goizet Cyril
- Guennoc Anne Marie
- Guyant-Maréchal Lucie
- Hannequin Didier
- Kaphan Elsa
- Labauge Pierre
- Laplaud David-Axel
- Le Page Emmanuelle
- Lebrun-Frenay Christine
- Levade Thierry
- Magnin Eloi
- Magy Laurent
- Masliah-Planchon Julien
- Mathis Stephane
- Menjot De Champfleur Nicolas
- Moreau Thibault
- Neau Jean-Philippe
- Ouallet Jean-Christophe
- Outteryck Olivier
- Pelletier Jean
- Pittion Sophie
- Taithe Frédérique
- Tournier-Lasserve Elisabeth
- Vermersch Patrick
- Verny Christophe
- Vukusic Sandra
- Wiertlewski Sandrine
- Zephir Helene
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 19/12/2014
- Field of study
International audienceInherited white matter diseases are rare and heterogeneous disorders usually encountered in infancy. Adult-onset forms are increasingly recognized. Our objectives were to determine relative frequencies of genetic leukoencephalopathies in a cohort of adult-onset patients and to evaluate the effectiveness of a systematic diagnostic approach. Inclusion criteria of this retrospective study were: (i) symmetrical involvement of white matter on the first available brain MRI; (ii) age of onset above 16 years. Patients with acquired diseases were excluded. Magnetic resonance imaging analysis identified three groups (vascular, cavitary and non-vascular/non-cavitary) in which distinct genetic and/or biochemical testing were realized. One hundred and fifty-four patients (male/female = 60/94) with adult-onset leukoencephalopathies were identified. Mean age of onset was 38.6 years. In the vascular group, 41/55 patients (75%) finally had a diagnosis [including CADASIL (cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy, n = 32) and COL4A1 mutation, n = 7]. In the cavitary group, 13/17 (76%) patients had a diagnosis of EIF2B-related disorder. In the third group (n = 82), a systematic biological screening allowed a diagnosis in 23 patients (28%) and oriented direct genetic screening identified 21 additional diseases (25.6%). Adult-onset genetic leukoencephalopathies are a rare but probably underestimated entity. Our study confirms the use of a magnetic resonance imaging-based classification with a final diagnosis rate of 64% (98/154) cases
Anionic polymerizations of non-polar monomers involving lithium
- Author
- A. A. Arest-Yakubovich
- A. A. Korotkov
- A. A. Korotkov
- A. C. Angood
- A. Cheminat
- A. D. H. Glague
- A. Davidjan
- A. Davidjan
- A. Davidjan
- A. Essel
- A. Essel
- A. F. Halasa
- A. F. Halasa
- A. F. Halasa
- A. F. Johnson
- A. F. Johnson
- A. F. Podolsky
- A. Garton
- A. Garton
- A. Garton
- A. Gatzke
- A. Guyot
- A. Guyot
- A. H. Cowley
- A. Hernandez
- A. Hirao
- A. J. Hagen
- A. N. Rodinov
- A. Okamoto
- A. R. Luxton
- A. R. Luxton
- A. Sivola
- A. Streitweser Jr.
- A. Streitwieser
- A. Streitwieser Jr.
- A. Vrancken
- A. W. Langer
- A. Yamagishi
- A. Yamagishi
- B. Francois
- B. Groof De
- B. J. Schmitt
- B. J. Schmitt
- B. L. Wakefield
- B. Y. Kimura
- C. A. Uraneck
- C. D. Eisenbach
- C. D. Eisenbach
- C. J. Dyball
- C. Kow
- C. L. Lee
- C. M. Selman
- C. Smedt De
- C. T. Viswanathan
- D. A. Bernard
- D. Ades
- D. Decker
- D. H. Beebe
- D. H. Richards
- D. H. Richards
- D. H. Richards
- D. H. Richards
- D. J. Kelley
- D. J. Worsfold
- D. J. Worsfold
- D. J. Worsfold
- D. J. Worsfold
- D. J. Worsfold
- D. J. Worsfold
- D. J. Worsfold
- D. M. French
- D. Margerison
- D. Margerison
- D. N. Bhattacharyya
- D. N. Bhattacharyya
- D. N. Crammond
- D. N. Schulz
- D. N. Schulz
- D. N. Schulz
- D. P. Wyman
- E. C. Steiner
- E. Campos-Lopez
- E. J. Panek
- E. M. Arnett
- E. Schoenberg
- E. Weiss
- F. Bandermann
- F. E. Naylor
- F. Hein
- F. J. Burgess
- F. M. Bower
- F. Rodriquez
- F. Schué
- F. Schué
- F. Schué
- G. A. Russell
- G. A. Russell
- G. B. Erussalimsky
- G. B. Erussalimsky
- G. Crassous
- G. D. Graham
- G. E. Coates
- G. E. Hartwell
- G. E. Hartwell
- G. Fraenkel
- G. G. Eberhardt
- G. G. Eberhardt
- G. Geerts
- G. Graham
- G. Helary
- G. Helary
- G. Jenner
- G. M. Burnett
- G. M. Whitesides
- G. O. Schulz
- G. Quack
- G. Quack
- G. R. Brubaker
- G. R. Peyton
- G. V. Kakova
- G. V. Rakova
- G. Wittig
- H. C. Wang
- H. Dietrich
- H. Gilman
- H. Hostalka
- H. Hostalka
- H. Hostalka
- H. Hsieh
- H. L. Hsieh
- H. L. Hsieh
- H. L. Hsieh
- H. L. Lewis
- H. L. Makowski
- H. Magnin
- H. S. Makowski
- H. Sinn
- H. Yuki
- I. Kminek
- I. Kminek
- I. Kuntz
- I. Kuntz
- I.-C. Wang
- J. Audureau
- J. B. Smart
- J. B. Smart
- J. Berkowitz
- J. C. Randall
- J. Chen
- J. Comyn
- J. Comyn
- J. Comyn
- J. Comyn
- J. E. L. Roovers
- J. E. L. Roovers
- J. E. L. Roovers
- J. Furukawa
- J. Geerts
- J. Inomata
- J. Komiyama
- J. M. Alvarino
- J. M. Catala
- J. N. Hay
- J. N. Hay
- J. N. Hay
- J. Pannell
- K. F. Elgert
- K. F. O'Driscoll
- K. F. O'Driscoll
- K. F. O'Driscoll
- K. Matsuzaki
- K. O'Driscoll
- K. S. Das
- K. Takahashi
- K. Takahashi
- K. Takahashi
- K. Ziegler
- K. Ziegler
- K. Ziegler
- L. A. Utracki
- L. J. Fetters
- L. J. Fetters
- L. J. Fetters
- L. J. Fetters
- L. J. Fetters
- L. J. Fetters
- L. J. Fetters
- L. L. Böhm
- L. M. Seitz
- L. V. Vinogradova
- L. V. Vinogradova
- L. V. Vinogradova
- L.V. Vinogradova
- M. Aldissi
- M. Doi
- M. F. Guest
- M. J. Jorgenson
- M. Kaspar
- M. Levy
- M. M. Al-Jarrah
- M. M. Exner
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Morton
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Szwarc
- M. Weiner
- M. Y. Darensburg
- M. Y. Medvedev
- N. C. Baird
- N. Hadjichristidis
- N. Roy
- N. Smirnowa
- N. Smirnowa
- P. Aubert
- P. Beak
- P. D. Bartlett
- P. D. Bartlett
- P. Lachance
- P. Mansson
- P. Masson
- P. West
- P. West
- R. A. Benkeser
- R. A. Finnegan
- R. Busson
- R. C. P. Cubbon
- R. Das
- R. E. Robertson
- R. E. Rundle
- R. H. Baney
- R. Jerome
- R. Koenig
- R. Mechin
- R. Milkovich
- R. Milner
- R. Milner
- R. N. Young
- R. O. Bach
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. P. Quirk
- R. Salle
- R. Stupfer
- R. T. Sanderson
- R. Wicke
- R. Wicke
- R. Zerger
- S. Brownstein
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Bywater
- S. Dumas
- S. F. Reed Jr.
- S. I. Beilin
- S. Kume
- S. Kume
- S. L. Aggarwall
- S. Suparno
- T. A. Antkowiak
- T. A. Antkowiak
- T. C. Cheng
- T. C. Cheng
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. L. Brown
- T. Suzuki
- T. Tanlak
- T. Uryu
- V. Collet-Marti
- V. D. Mochel
- V. D. Mochel
- V. Halaska
- V. Halaska
- V. P. Yudin
- V. R. Sandel
- V. V. Shamanim
- W. A. Nugent
- W. G. Glaze
- W. Gerbert
- W. H. Glaze
- W. H. Glaze
- W. H. Glaze
- W. H. Glaze
- W. H. Glaze
- W. Nentwig
- W. W. Graessley
- Y. L. Spirih
- Y. L. Spirin
- Y. L. Spirin
- Y. L. Spirin
- Y. Tanaka
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1984
- Field of study
[The effect of low-dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock].
- Author
- Abbey Ianthe
- Abdel Rehim Marwa
- Abdel Rehim Marwa
- Abdul Rahman A
- Abduljawwad Emad
- Abduljawwad Emad
- Abe Emuri
- Abe Ryuzo
- Aboab Jerome
- Aboab Jerome
- Acevedo Juan
- Acharya Anand
- Acquarolo Annamaria
- Acquarolo Annamaria
- Adamzik Michael
- Adamzik Michael
- Adembri Chiara
- Adrie Christophe
- Adrie Christophe
- Afessa Bekele
- Ainoda Yusuke
- Aiyar S
- Al Dabbagh Tarek
- Al Dabbagh Tarek
- Al Knawy Bandar A
- Al Knawy Bandar A
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Abdulkareem Abdulmajeed
- Al-Arabi Rida
- Al-Dorzi Hasan M
- Al-Dorzi Hasan M
- Al-Muhamadi Ali
- Al-Naeeb Yasseen
- Al-Naeeb Yasseen
- Al-Shaer Mohammad
- Al-Shaer Mohammad
- Al-Tamimi Waleed
- Al-Tamimi Waleed
- Alaniz Cesar
- Alevizaki Maria
- Alevizaki Maria
- Alinejad Faranak
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- AlJumah Abdulrahman
- Allolio Bruno
- AlNajjar Taghreed
- AlNajjar Taghreed
- Altintas M A
- Alvarez Jean-Claude Claude
- Alvarez Jean-Claude Claude
- Alvarez Jean-Claude Claude
- Amano Kosaku
- Amano Kosaku
- Amathieu Roland
- Amathieu Roland
- Amathieu Roland
- Amathieu Roland
- Ambriz-Plascencia Ana Rosa
- Ameen Abdelbadee
- Ameen Abdelbadee
- Amini Amir
- Amini Amir
- Amini Amir
- Amos Taryn
- Amour Julien
- Anderegg Brent A
- Anderegg Brent A
- Andersson Liane
- Andersson Liane
- Andrade Bertha Coelho
- Androulakis Ioannis P
- Aneja Rajesh
- Angus Derek C
- Angus Derek C
- Anjum Aisha
- Anjum Aisha
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annetta M
- Antonelli M
- Antonopoulou Anastasia N
- Antonopoulou Anastasia N
- Antonucci E
- Apollonatou Sofia
- Apollonatou Sofia
- Apostolidou Efterpi N
- Apostolidou Efterpi N
- Apostolou K
- Apostolou K
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Arabi Yaseen M
- Araujo Leonardo V
- Aravinthan Aloysious
- Aravinthan Aloysious
- Arbor Ann
- Arlt Wiebke
- Arlt Wiebke
- Armaganidis Apostolos
- Armaganidis Apostolos
- Armaganidis Apostolos
- Armaganidis Apostolos
- Aronowitz Paul
- Arriagada S Daniela
- Arroyo Vicente
- Arroyo Vicente
- Asahata Sayaka
- Asehnoune Karim
- Asehnoune Karim
- Asfar Pierre
- Asfar Pierre
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Ashby Deborah
- Atay Suleyman
- Atrash Jawad
- Atrash Jawad
- Aufort Sophie
- Aufort Sophie
- Augustatou Callirhoe
- Avidan Alexander
- Awasthi Shally
- Aya Hollmann D
- Aya Hollmann D
- Ayestaran Ignacio
- Ayestaran Ignacio
- Ayestaran Jose I
- Ayestaran Jose I
- Azoulay Elie
- Azoulay Elie
- Babajani Rafat
- Bagshaw Sean M
- Baharoon Salim
- Baharoon Salim
- Bailly-Salin Juliette
- Bailly-Salin Juliette
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Aaron C
- Baker Tim
- Bander Joseph
- Banner Christina
- Barbeiro Hermes Vieira
- Barbosa Decio Sabbatini
- Barbosa Decio Sabbatini
- Barel Remy
- Barel Remy
- Barnett Adrian G
- Barnett Adrian G
- Barouk Jerome D
- Barton Michelle H
- Barton Michelle H
- Barton Michelle H
- Barton Michelle H
- Bauer Seth R
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Beale Richard J
- Behrend Ellen N
- Behrend Ellen N
- Bein Thomas
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Beishuizen Albertus
- Belkouchi Abdelkader
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellissant Eric
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benbenishty Julie
- Bendel Stepani
- Benkabbou Amine
- Bennett Stephanie
- Bennett Stephanie
- Benson Sven
- Benson Sven
- Bercker Sven
- Bercker Sven
- Berger Mette M
- Berghall Elisabeth
- Berghall Elisabeth
- Berghaus R
- Berghaus R
- Bergt Stefan
- Bernardin Gilles
- Bernardin Gilles
- Bersten Andrew D
- Bertin-Maghit Marc
- Berton Christine
- Bertrand Jean Claude
- Best Al M
- Bhadada Sanjay
- Bhansali Anil
- Bhatia Vijaylaxmi
- Bhojwani K
- Bijkerk Ronald M
- Bilkovski Robert
- Bingel Ulrike
- Bingisser Roland
- Bingisser Roland
- Bissell Brittany D
- Bissell Brittany D
- Blanchard Anne
- Blanchard Anne
- Bloomfield Roxanna
- Blum Claudine A
- Boden L A
- Bogatsch Holger
- Bogatsch Holger
- Bohe Julien
- Bohe Julien
- Bokhari Faran
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Bollaert Pierre Edouard
- Boney Charlotte M
- Boonen Eva
- Borba Evandro Lucas de
- Bornstein Stefan R
- Bosman Rob J
- Bosman Rob J
- Bosson Jean-Luc
- Botoula E
- Botoula E
- Boucly Catherine
- Boucly Catherine
- Boudou Philippe
- Bouloux Pierre-Marc
- Bouloux Pierre-Marc
- Boutron Carole M
- Bouzat Pierre
- Bozkurt Ahmet
- Bozkurt Ahmet
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Brett Stephen J
- Briassouli E
- Briassouli E
- Briassoulis G
- Briassoulis G
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Briegel Josef
- Brierley Joe
- Brindley Peter G
- Brito Vinicius Nahime
- Brito Vinicius Nahime
- Brits Riette
- Brits Riette
- Britt L D
- Britt R C
- Brocas E
- Brockmeier Diane
- Broux Christophe
- Broux Christophe
- Brown Glen
- Brun-Buisson Christian
- Brun-Buisson Christian
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Brunkhorst Frank M
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bruno Jeffrey Joseph
- Bubser Florian
- Buchele Gustavo Luiz
- Buchman Timothy G
- Buisson Christian Brun
- Buno Antonio
- Burkitt Jamie M
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burroughs Andrew Kenneth
- Burry Lisa
- Burry Lisa
- Busch K H
- Butcher Stephen K
- Butschkau Antje
- Caillaud Denis
- Cakir E
- Calandra Thierry
- Calandra Thierry
- Caldera Maria V
- Caldwell Ellen
- Caldwell Ellen
- Calvano Steve E
- Calvano Steve E
- Candido-Vitto Cristina
- Caputo C
- Carcillo Joseph A
- Carcillo Joseph A
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Cariou Alain
- Carlier Robert
- Carlier Robert
- Carmean Amanda
- Carmean Amanda
- Carori Giampiero
- Carori Giampiero
- Carr Julie
- Carr Julie
- Carrilho Alexandre Jose Faria
- Carrilho Alexandre Jose Faria
- Carson Stephanie J
- Casanova Bonaventura
- Casanova Elena
- Casanova-Cardiel Luis Javier
- Cassar Charmaine
- Casserly Brian
- Casserly Brian
- Castanon-Gonzalez Jorge Alberto
- Castel Muriel
- Catravas John
- Cavaliere F
- Cazalis Marie-Angelique
- Cecconi Maurizio
- Cecconi Maurizio
- Cepkova Magda
- Cepkova Magda
- Cesari-Giordani Jean Francois
- Cesari-Giordani Jean Francois
- Cha Stephen S
- Chabre Olivier
- Chabre Olivier
- Chagnon Frederic
- Chagnon Frederic
- Chagnon Jean-Luc
- Chagnon Jean-Luc
- Chaney Whitney
- Chaney Whitney
- Chang Xiao
- Chang Xiao
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanques Gerald
- Chanson Anne Laure
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chapman Marianne J
- Chappuis Philippe
- Charier David
- Charpentier Claire
- Charpentier Claire
- Chastre Jean
- Chastre Jean
- Chaudhury Prosanto
- Chaudry Irshad H
- Chen Huan-Wen
- Chen Luni
- Chen Ofer
- Chen Pang-Chi
- Chen Yung-Chang
- Chen Zhi
- Cherfan Antoine J
- Cherfan Antoine J
- Cherfan Antoine J
- Cherfan Antoine J
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chevret Sylvie
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chew Victoria W
- Chia Wai-Kit
- Chiolero Rene
- Chiriac Stefan
- Chittawatanarat Kaweesak
- Chittawatanarat Kaweesak
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Cho Kiho
- Chohnabayashi N
- Choi Hye-Sook
- Choi Hye-Sook
- Choi Seong-Soo
- Cholley Bernard P
- Choong Karen
- Choong Karen
- Chouinard Lucie
- Chouinard Lucie
- Chouker Alexander
- Chraibi Ahmed
- Chraibi Ahmed
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- Czeslick Elke
- D'honneur Gilles
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- Dimopoulou Ioanna
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- Donati Yannis
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- dos Santos Jose Wellington A
- Douglas Ivor S
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- Douka Evangelia
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- Faure Patrice
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- Festti Josiane
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- Finfer Simon
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- Finkielman Javier D
- Fiorese Bertilla
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- Fisher Gene
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- Forceville Xavier
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- Forst Helmuth
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- Fries Michael
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- Frostell Claes
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- Fuchs Paul Ch
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- Gallix Benoit
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- Gallo-Payet Nicole
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- Gentilhomme Anne
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- Gerlach Herwig
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- Gerlach Herwig
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- Ghosh Sujoy Shubhra
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- Giannoni Eric
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- Grander Wilhelm
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- Grion Cintia Magalhaes Carvalho
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- Groeneveld Arie Bastiaan Johan
- Groeneveld Arie Bastiaan Johan
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- Hammer Fabian
- Han Seo Goo
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- Hovilehto Seppo
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- Hsieh Susan
- Hsu Hui-Chi
- Hu Bo
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- Hua Chung-Ching
- Hua Chung-Ching
- Huang Chun-Jui
- Huang Karen E
- Huang Ruolan
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- Huber-Lang Markus
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- Hyzy Robert
- Ibanez Jordi
- Ibanez Jordi
- Ibanez Jordi
- Ibanez Jordi
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- Ilias Ioannis
- Ilias Ioannis
- Ilias Ioannis
- Imamoglu Mustafa
- Imeson Lee
- Indyk Justin A
- Ioakeimidou Aikaterini
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- Iwaki Noriko
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- Jaalam K
- Jaber Samir
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- Jelastopoulou Eleni
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- Jochberger Stefan
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- Johan Groeneveld A B
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- Juneja Deven
- Jung Boris
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- Jutla Sukhdeep
- Juutilainen Auni
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- Kache Saraswati
- Kado-Fong Helen
- Kaidomar Michel
- Kaidomar Michel
- Kalafateli Maria
- Kalenka Armin
- Kalpakou Georgia Th
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- Kamarul Iman Musa K
- Kamisoglu Kubra
- Kaneko Tadashi
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- Kang Eun-Hae Eunhae
- Kang Eun-Hae Eunhae
- Kappel Dean
- Karaguzel Gungor Gulay
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- Kashiwabara Moto
- Katagami Hideki
- Katagiri Satosi
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- Kawamata Takakazu
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- Keh Didier
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- Khangoora Vikramjit
- Khashana Abdelmoneim
- Kiff Jane
- Kikuchi Ken
- Kilger E
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- Kim Chol
- Kim Dong Soon
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- Kim Hojoong
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- Kluge Stefan
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- Knaup Reymond Marlies
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- Knawy Bandar Al
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- Knippschild Uwe
- Ko Clarence Ching-Huat
- Kobbe Philipp
- Kocak Mehmet
- Kocak Mehmet
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- Koh Won-Jung
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- Kon Alexander
- Konstandelou Evangellia
- Konstandelou Evangellia
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- Kotanidou Anastasia
- Kotanidou Anastasia
- Kotanidou Anastasia
- Kotanidou Anastasia
- Kotsaki Antigone
- Kox Matthijs
- Kraemer Dale F
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- Kreth Simone
- Kruger Peter
- Kubo Osami
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- Kubo Toshio
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- Kuchel Timothy R
- Kufera Joseph A
- Kuhn Sven-Olaf
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- Kuittinen Taru
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- Kullmann Jennifer S
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- Kuo Chin-Sung
- Kupfer Yizhak
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- Kwizera Arthur
- Kwon O Jung
- Kwon O Jung
- Kwon O Jung
- Kwon O Jung
- Kwon Yong Soo
- Kwon Yong Soo
- Kwon Yong Soo
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- Larsson Anders
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- Lauzier Francois
- Lavenu A
- Laviolle Bruno
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- Lawson Margaret
- Le Maguet Pascale
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- Lecuyer L
- Ledderose Carola
- Lee Chih-Hsin
- Lee Ming-Chia
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- Lee Sang D O
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- Leemingsawat Chantanij
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- Lehmke Josefa
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- Lejeune Julie
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- Lekkou Alexandra A
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- Lemeshow Stanley
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- Li Chun-Sheng Chen
- Li Chun-Sheng Chen
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- Li Enyou
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- Li I-Ting
- Li Jinyue Jian-guo
- Li Jinyue Jian-guo
- Li Jinyue Jian-guo
- Li Lu
- Li Lu
- Li Yi
- Liang Hui
- Liang Hui
- Liao Kuo-Meng
- Liaudet L
- Lichte Philipp
- Lien Jau-Min
- Lim Chae-Man
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- Lima-Valassi Helena Pantelion
- Lima-Valassi Helena Pantelion
- Limbeck Elisabeth
- Limor Rona
- Lin John
- Lindenauer Peter K
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- Liotier Jerome
- Lipcsey Miklos
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- Lipiner-Friedman Diane
- Listernick Robert
- Little Anjuli
- Little Anjuli
- Liu Chang
- Liu Chang
- Liu Nai-Jeng
- Liu Yu-Chih
- Liu Yu-Chih
- Livaditi Olga
- Livaditi Olga
- Livaditi Olga
- Livaditi Olga
- Llompart-Pou Juan Antonio
- Llompart-Pou Juan Antonio
- Llompart-Pou Juan Antonio
- Llompart-Pou Juan Antonio
- Lo Yuan-Hao
- Loeffler Markus
- Loeffler Markus
- Lofaso Frederic
- Loisa Pekka
- Loisa Pekka
- Loisa Pekka
- Loisa Pekka
- Loisa Pekka
- London Vanessa
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- Loriaux D Lynn
- Lorts Angie
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- Luo Yun
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- Madero Rosario
- Madgundi Venugopal V
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- Magri Silvia
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- Makino Hiroshi
- Malik Iqbal A
- Mallat Jihad
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- Maralihalli M B
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- Marklin Gary
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- Massart Catherine
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- Matsushita Kazuyuki
- Matsutani Takeshi
- Maviglia R
- Mavrommatis Antonis
- Mavrommatis Antonis
- Maxime Virginie
- Maxime Virginie
- Maxime Virginie
- Maxime Virginie
- Maxime Virginie
- Maxime Virginie
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- Mazzuco Tania Longo
- Mazzuco Tania Longo
- McArthur Colin
- McArthur Colin
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- McGree James
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- McLean Anthony S
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- Meersseman Philippe
- Megarbane Bruno
- Megarbane Bruno
- Meggison Hilary
- Mehta Renuka
- Mehta Sangeeta K
- Mehta Sangeeta K
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- Mehta Sangeeta K
- Meier-Hellmann Andreas
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- Meng Xinke
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- Mentzelopoulos Spyros
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- Mercier Gregoire
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- Nesseler Nicolas
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- Nousiainen Tapio
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- Orlander Philip R
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- Wright Robert
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- Wu Huang-Pin
- Wu Ling-Yi
- Wu Ta-Wei
- Wynn James L
- Xirouchakis Elias
- Xu Jun
- Xu Mujuan
- Xu Mujuan
- Yamamoto Masakazu
- Yamamoto Masakazu
- Yamashita Kiyohiko
- Yang Chunli
- Yang Chunli
- Yee Kristen S
- Yee Kristen S
- Yeh Timothy
- Yu Chung-Chieh
- Yu Chung-Chieh
- Yu Jihion
- Yu Teng-Jen
- Yu Teng-Jen
- Yu Xuezhong
- Yu Yuan-Bin
- Yu Zhui
- Yu Zhui
- Yuan Ying
- Zabalza Michel
- Zakynthinos Spyros
- Zakynthinos Spyros
- Zaloga Gary
- Zaman Muhammad
- Zampieri Fernando Godinho
- Zamri-Saad M
- Zandstra Durk F
- Zandstra Durk F
- Zaritsky Arno
- Zeni Fabrice
- Zervou Maria
- Zhang Fengmin
- Zhang Fengmin
- Zhang Haibo
- Zhang Haibo
- Zhang Qian
- Zhang Qian
- Zhang Yang
- Zhang Yang
- Zhang Zhong
- Zhang Zhong
- Zhao Xin
- Zhao Xin
- Zheng Juanjuan
- Zheng Juanjuan
- Zheng Liangliang
- Zhou Qing
- Zhou Qing
- Zhu Huadong
- Ziegenfuss Marc
- Ziegenfuss Marc
- Zijlstra J G
- Zimmerman Jerry J
- Zimmerman Jerry J
- Zuckerberg Aaron
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/10/2007
- Field of study
Intravenous NPA for the treatment of infarcting myocardium early: InTIME-II, a double-blind comparison on of single-bolus lanoteplase vs accelerated alteplase for the treatment of patients with acute myocardial infarction
- Author
- Adamczak M.
- Adams E.
- Adams P. C.
- Adi I.
- Admant P.
- Ahir S.
- Ahsan A. J.
- Akadirik A.
- Akgöz H.
- AkgĂĽn G.
- Akhtar J.
- AkyĂĽrek O.
- Al Shwafi K.
- Al-Khafaji M. N.
- Alagha Z.
- Alan D.
- Albers C. J.
- Albuquergue A.
- Albuquerque D.
- Aldica M.
- Alhabaj S.
- Alonso-Orcajo N.
- Altmann E.
- Altybernd B.
- Amat G.
- Ambrosioni E.
- Andersen C. B.
- Anderson C.
- Anderson J.
- Anderson N.
- Andre A. A.
- Andrea B.
- Andreassen G.
- Andresen D.
- Angehrn W.
- Anneveldt A.
- Antman E.
- Apetrei E.
- Apffel F.
- Appenrodt H.
- Ardill R.
- Arribas Jimenez A.
- Ashton T.
- Aswad K.
- Attassi K.
- Averkov O.
- Ayestaran J. I.
- Ayoub J. C. A.
- Baars H. F.
- Bachmann S.
- Badano L.
- Bahr R.
- Baig M. M. E.
- Bailey R. J.
- Baillie H.
- Bain R. J. I.
- Balanescu S.
- Baldacci G.
- Baldew S. C.
- Balli E.
- Balsera B. B. G.
- Balázová K.
- Banas J.
- Banaszewski M.
- Banda D.
- Baradat G.
- Baran K.
- Bareiss P.
- Baretta G.
- Barras C.
- Barrero C.
- Barthers F. B.
- Bartolucci J.
- Basilier E.
- Basu A.
- Bata I.
- Batur M. K.
- Baudet M.
- Baudouy M.
- Bauhuber I.
- Bayata S.
- Beal A.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2000
- Field of study
Aims to compare the efficacy and safety of lanoteplase, a single-bolus thrombolytic drug derived from alteplase tissue plasminogen activator, with the established accelerated alteplase regimen in patients presenting within 6 h of onset of ST elevation acute myocardial infarction. Methods and Results 15 078 patients were recruited from 855 hospitals worldwide and randomized in a 2:1 ratio to receive either lanoteplase 120 KU. kg-1 as a single intravenous bolus, or up to 100 mg accelerated alteplase given over 90 min. The primary end-point was all-cause mortality at 30 days and the hypothesis was that the two treatments would be equivalent. By 30 days, 6.61% of alteplase-treated patients and 6.75% lanoteplase-treated patients had died (relative risk 1.02). Total stroke occurred in 1.53% alteplase- and 1.87% lanoteplase-treated patients (ns); haemorrhagic stroke rates were 0.64% alteplase and 1.12% lanoteplase (P=0.004). The net clinical deficit of 30-day death or non-fatal disabling stroke was 7.0% and 7.2%, respectively. By 6 months, 8.8% of alteplase-treated patients and 8.7% of lanoteplase-treated patients had died. Conclusion Single-bolus weight-adjusted lanoteplase is an effective thrombolytic agent, equivalent to alteplase in terms of its impact on survival and with a comparable risk-benefit profile. The single-bolus regimen should shorten symptoms to treatment times and be especially convenient for emergency department or out-of-hospital administration. (C) 2000 The European Society of Cardiology