448 research outputs found

    A voltage limiter circuit for indoor light energy harvesting applications

    Get PDF
    A voltage limiter circuit for indoor light energy harvesting applications is presented. This circuit is a part of a bigger system, whose function is to harvest indoor light energy, process it and store it, so that it can be used at a later time. This processing consists on maximum power point tracking (MPPT) and stepping-up, of the voltage from the photovoltaic (PV) harvester cell. The circuit here described, ensures that even under strong illumination, the generated voltage will not exceed the limit allowed by the technology, avoiding the degradation, or destruction, of the integrated die. A prototype of the limiter circuit was designed in a 130 nm CMOS technology. The layout of the circuit has a total area of 23414 mu m(2). Simulation results, using Spectre, are presented

    MAP Kinases Pathways in Gastric Cancer.

    Get PDF

    The PEP Survey: Infrared Properties of Radio-Selected AGN

    Full text link
    By exploiting the VLA-COSMOS and the Herschel-PEP surveys, we investigate the Far Infrared (FIR) properties of radio-selected AGN. To this purpose, from VLA-COSMOS we considered the 1537, F[1.4 GHz]>0.06 mJy sources with a reliable redshift estimate, and sub-divided them into star-forming galaxies and AGN solely on the basis of their radio luminosity. The AGN sample is complete with respect to radio selection at all z<~3.5. 832 radio sources have a counterpart in the PEP catalogue. 175 are AGN. Their redshift distribution closely resembles that of the total radio-selected AGN population, and exhibits two marked peaks at z~0.9 and z~2.5. We find that the probability for a radio-selected AGN to be detected at FIR wavelengths is both a function of radio power and redshift, whereby powerful sources are more likely to be FIR emitters at earlier epochs. This is due to two distinct effects: 1) at all radio luminosities, FIR activity monotonically increases with look-back time and 2) radio activity of AGN origin is increasingly less effective at inhibiting FIR emission. Radio-selected AGN with FIR emission are preferentially located in galaxies which are smaller than those hosting FIR-inactive sources. Furthermore, at all z<~2, there seems to be a preferential (stellar) mass scale M ~[10^{10}-10^{11}] Msun which maximizes the chances for FIR emission. We find such FIR (and MIR) emission to be due to processes indistinguishable from those which power star-forming galaxies. It follows that radio emission in at least 35% of the entire AGN population is the sum of two contributions: AGN accretion and star-forming processes within the host galaxy.Comment: 13 pages, 14 figures, to appear in MNRA

    Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris

    Get PDF
    Advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), resulting from non-enzymatic modifications of proteins, are potentially harmful to human health. They directly act on proteins, affecting structure and function, or through receptor-mediated mechanisms. RAGE, a type I transmembrane glycoprotein, was identified as a receptor for AGEs. RAGE is involved in chronic inflammation, oxidative stress-based diseases and ageing. The majority of RAGE ligands bind to the VC1 domain. This domain was successfully expressed and secreted by Pichia pastoris. Out of two N-glycosylation sites, one (Asn25) was fully occupied while the other (Asn81) was under-glycosylated, generating two VC1 variants, named p36 and p34. Analysis of N-glycans and of their influence on VC1 properties were here investigated. The highly sensitive procainamide labeling method coupled to ES-MS was used for N-glycan profiling. N-glycans released from VC1 ranged from Man9GlcNAc2- to Man15GlcNAc2- with major Man10GlcNAc2- and Man11GlcNAc2- species for p36 and p34, respectively. Circular dichroism spectra indicated that VC1 maintains the same conformation also after removal of N-glycans. Thermal denaturation curves showed that the carbohydrate moiety has a small stabilizing effect on VC1 protein conformation. The removal of the glycan moiety did not affect the binding of VC1 to sugar-derived AGE- or malondialdehyde-derived ALE-human serum albumin. Given the crucial role of RAGE in human pathologies, the features of VC1 from P. pastoris will prove useful in designing strategies for the enrichment of AGEs/ALEs from plasma, urine or tissues, and in characterizing the nature of the interaction

    The Far-Infrared, UV and Molecular Gas Relation in Galaxies up to z=2.5

    Full text link
    We use the infrared excess (IRX) FIR/UV luminosity ratio to study the relation between the effective UV attenuation (A_IRX) and the UV spectral slope (beta) in a sample of 450 1<z<2.5 galaxies. The FIR data is from very deep Herschel observations in the GOODS fields that allow us to detect galaxies with SFRs typical of galaxies with log(M)>9.3. Thus, we are able to study galaxies on and even below the main SFR-stellar mass relation (main sequence). We find that main sequence galaxies form a tight sequence in the IRX--beta plane, which has a flatter slope than commonly used relations. This slope favors a SMC-like UV extinction curve, though the interpretation is model dependent. The scatter in the IRX-beta plane, correlates with the position of the galaxies in the SFR-M plane. Using a smaller sample of galaxies with CO gas masses, we study the relation between the UV attenuation and the molecular gas content. We find a very tight relation between the scatter in the IRX-beta plane and the specific attenuation (S_A), a quantity that represents the attenuation contributed by the molecular gas mass per young star. S_A is sensitive to both the geometrical arrangement of stars and dust, and to the compactness of the star forming regions. We use this empirical relation to derive a method for estimating molecular gas masses using only widely available integrated rest-frame UV and FIR photometry. The method produces gas masses with an accuracy between 0.12-0.16 dex in samples of normal galaxies between z~0 and z~1.5. Major mergers and sub-millimeter galaxies follow a different S_A relation.Comment: 11 pages, 6 pages appendix, 11 figures, accepted to Ap

    Probing the Timescale of the 1.4 GHz Radio emissions as a Star formation tracer

    Full text link
    Radio used as a star formation rate (SFR) tracer presents enormous advantages by being unaffected by dust and radio sources being pinpointed at the sub-arc-second level. The interpretation of the low frequency 1.4 GHz luminosity is hampered by the difficulty in modeling the cosmic ray paths in the interstellar medium, and their interactions with the magnetic field. In this work, we compare the SFR derived from radio observations, and the ones derived from spectral energy distribution (SED) modeling. We aim at better understand the behavior of the SFR radio tracer, with a specific emphasis on the link with star-formation histories. We used the SED modeling code Code Investigating GALaxy Emission, CIGALE, with a non-parametric star formation history model (SFH) and fit the data over the wavelength range from the ultraviolet (UV) up to the mid-infrared (mid-IR). We interpret the difference between radio and SED-based SFR tracers in the light of recent gradients in the derived SFH. To validate the robustness of the results, we checked for any remaining active galaxy nuclei (AGN) contribution and tested the impact of our SFH modeling approach. Approximately 27% our galaxies present a radio SFR (SFRradio_{\rm radio}) at least ten times larger than the instantaneous SFR from SED-fitting (SFRSED_{\rm SED}). This trend affects primarily the galaxies that show a declining SFH activity over the last 300 Myr. Both SFR indicators converge toward a consistent value, when the SFHs are averaged over a period larger than 150 Myr to derive SFRSED_{\rm SED}. Although the radio at low frequency 1.4 GHz is a good tracer of the star formation activity of galaxies with constant or increasing SFH, our results indicate that this is not the case for galaxies that are quenching. Our analysis suggests that the star formation time sensitivity of the radio low frequency could be longer than 150 Myr.Comment: 10 pages, 10 figure

    PACS Evolutionary Probe (PEP) - A Herschel Key Program

    Get PDF
    Deep far-infrared photometric surveys studying galaxy evolution and the nature of the cosmic infrared background are a key strength of the Herschel mission. We describe the scientific motivation for the PACS Evolutionary Probe (PEP) guaranteed time key program and its role in the complement of Herschel surveys, and the field selection which includes popular multiwavelength fields such as GOODS, COSMOS, Lockman Hole, ECDFS, EGS. We provide an account of the observing strategies and data reduction methods used. An overview of first science results illustrates the potential of PEP in providing calorimetric star formation rates for high redshift galaxy populations, thus testing and superseeding previous extrapolations from other wavelengths, and enabling a wide range of galaxy evolution studies.Comment: 13 pages, 12 figures, accepted for publication in A&

    Herschel Far-IR counterparts of SDSS galaxies: Analysis of commonly used Star Formation Rate estimates

    Full text link
    We study a hundred of galaxies from the spectroscopic Sloan Digital Sky Survey with individual detections in the Far-Infrared Herschel PACS bands (100 or 160 μ\mum) and in the GALEX Far-UltraViolet band up to z\sim0.4 in the COSMOS and Lockman Hole fields. The galaxies are divided into 4 spectral and 4 morphological types. For the star forming and unclassifiable galaxies we calculate dust extinctions from the UV slope, the Hα\alpha/Hβ\beta ratio and the LIR/LUVL_{\rm IR}/L_{\rm UV} ratio. There is a tight correlation between the dust extinction and both LIRL_{\rm IR} and metallicity. We calculate SFRtotal_{total} and compare it with other SFR estimates (Hα\alpha, UV, SDSS) finding a very good agreement between them with smaller dispersions than typical SFR uncertainties. We study the effect of mass and metallicity, finding that it is only significant at high masses for SFRHα_{H\alpha}. For the AGN and composite galaxies we find a tight correlation between SFR and LIR_{IR} (σ\sigma\sim0.29), while the dispersion in the SFR - LUV_{UV} relation is larger (σ\sigma\sim0.57). The galaxies follow the prescriptions of the Fundamental Plane in the M-Z-SFR space.Comment: 24 pages, 23 figures, accepted for publication in MNRA

    Dust temperature and CO-to-H2 conversion factor variations in the SFR-M* plane

    Full text link
    Deep Herschel imaging and 12CO(2-1) line luminosities from the IRAM PdBI are combined for a sample of 17 galaxies at z>1 from the GOODS-N field. The sample includes galaxies both on and above the main sequence (MS) traced by star-forming galaxies in the SFR-M* plane. The far-infrared data are used to derive dust masses, Mdust. Combined with an empirical prescription for the dependence of the gas-to-dust ratio on metallicity (GDR), the CO luminosities and Mdust values are used to derive for each galaxy the CO-to-H2 conversion factor, alpha_co. Like in the local Universe, the value of alpha_co is a factor of ~5 smaller in starbursts compared to normal star-forming galaxies (SFGs). We also uncover a relation between alpha_co and dust temperature (Tdust; alpha_co decreasing with increasing Tdust) as obtained from modified blackbody fits to the far-infrared data. While the absolute normalization of the alpha_co(Tdust) relation is uncertain, the global trend is robust against possible systematic biases in the determination of Mdust, GDR or metallicity. Although we cannot formally distinguish between a step and a smooth evolution of alpha_co with the dust temperature, we can conclude that in galaxies of near-solar metallicity, a critical value of Tdust=30K can be used to determine whether the appropriate alpha_co is closer to the starburst value (1.0 Msun(K kms pc^2)^-1, if Tdust>30K) or closer to the Galactic value (4.35 Msun (K kms pc^2)^-1, if Tdust<30K). This indicator has the great advantage of being less subjective than visual morphological classifications of mergers/SFGs, which can be difficult at high z because of the clumpy nature of SFGs. In the absence of far-infrared data, the offset of a galaxy from the main sequence (i.e., log[SSFR(galaxy)/SSFR_MS(M*,z)]) can be used to identify galaxies requiring the use of an alpha_co conversion factor lower than the Galactic value.Comment: Accepted for publication in Astronomy and Astrophysics (A&A); 15 pages, 6 figures; V2: updated reference lis
    corecore