Agrobiodiversity Products by SWOT Analysis as an Analysis for Strategic Innovation

The paper aimed to demonstrate the potential of agro-biodiversity products derived from medicinal plants of the family farmers in Profito network (specific program of the Brazilian government). Method used was scenarios analysis of the knowledge. Literature review it was in the scientific database. According to the new "green wave" created by contemporary society aiming a better health and quality of life by population, it led to the depredation of medicinal species due to the acceleration of global trade demand. Thus, was constructed a SWOT analysis to support managers in strategic planning through of the potential agro-biodiversity products. It shows the appreciation of environmentally conscious products, economically sustainable and the creation of new public policies that ensure and valuation to the rescue, conservation and sustainable use of biodiversity since they are essential for building this niche market

Apropriação do raciocínio combinatório nos movimentos de peças de um jogo e na construção de diagramas de árvore

Este trabalho objetiva tornar conhecida a proposta de ensino-aprendizagem acerca de conteúdos básicos de combinatória por meio de um jogo de tabuleiro ‘Grelha quadrada 3 x 3`. A proposta deste jogo está em consonância com indicações presentes na BNCC – Base Nacional Comum Curricular (BRASIL, 2018) para o ensino e aprendizagem de Matemática nos anos iniciais do Ensino Fundamental, e visa fomentar a apropriação, o exercício e o desenvolvimento do raciocínio combinatório enquanto as possibilidades de tomadas de decisão relativas à movimentação de tampinhas de garrafa pet sobre o tabuleiro de um jogo são avaliadas, enquanto um diagrama de árvore mostrando essas possibilidades vai sendo construído em paralelo. O desenrolar das análises de possibilidades de jogadas deu-se logo após o início de uma partida (antes da primeira movimentação) e a partir de um dado momento de jogo até que a partida chegasse ou não ao seu final. Em prosseguimento, após o consequente reconhecimento das regras do jogo, foram propostos problemas de combinatória aos jogadores, conforme preconiza a teoria de Resolução de Problemas, (ONUCHIC, 1999). Trata-se de uma pesquisa bibliográfica que culminou com a proposição do jogo, segundo o qual se objetivou dimensionar a importância e a contribuição que a proposição e criação de um jogo didático representam para a melhoria do processo de ensino aprendizagem de combinatória com estudantes dos anos iniciais, em particular arvores de possibilidades, bem como disponibilizar material didático para uso de professores

A busca por uma ou mais estratégias ganhadoras em um jogo combinatório de tabuleiro

This work aims to make known the teaching-learning proposal about objects of basic knowledge of Combinatorics through a combinatorial game of strategy, on a board named Grid Quadrada 3 x 3, in line with the indications present in the Common National Curricular Base (BNCC) for students from the 5th Elementary School Year. The proposal aims to encourage the appropriation, exercise and development of combinatorial reasoning in decision-making regarding the movement of pet bottle caps on the board according to established rules, in order to construct a tree diagram that shows all the possibilities for the development of a match, from the initial movement, in order to evaluate the existence or not of one or more winning strategies, for each player. This is a bibliographical research that culminated in the proposal of the game, according to which the objective is to measure the importance and what contribution such a game represents for the improvement of teaching and learning of Combinatorics and to provide didactic material for use by teachers.Este trabalho objetiva tornar conhecida proposta ensino-aprendizagem acerca objetos de conhecimentos básicos de Combinatória por meio jogo combinatório de estratégia, em tabuleiro nomeado Grelha Quadrada 3 x 3, em consonância com indicações presentes Base Nacional Curricular Comum (BNCC) para estudantes a partir do 5º Ano Ensino Fundamental. A proposta visa fomentar a apropriação, exercício e desenvolvimento do raciocínio combinatório nas tomadas de decisão relativas à movimentação tampinhas garrafa pet sobre o tabuleiro consoante regras estabelecidas, de modo construir um diagrama de árvore que mostre todas as possibilidades do desenrolar de uma partida, desde o movimento inicial, de modo a avaliar a existência ou não uma ou mais estratégias ganhadoras, para cada jogador. Trata-se de uma pesquisa bibliográfica que culminou com a proposta do jogo, segunda a qual objetiva-se dimensionar qual importância e qual contribuição tal jogo representa para a melhoria do ensino-aprendizagem de Combinatória e disponibilizar material didático para uso dos professores

Micronutrients as an Innovation Opportunity for the Pharmaceutical Industry: A Case Study of Vitamin D in Brazil

This paper aims to demonstrate the micronutrients as an attractive alternative of innovation for Pharmaceutical Industries with limited resources. A case study of vitamin D as a pharmaceutical supplement is launched in the Brazilian Market. The results demonstrate that some opportunities of several new products for populations with nutritional deficiency—the so-called micronutrients for hidden hunger, that is any deficiency unnoticed where micronutrients assume metabolic functions in humans. This deficiency unnoticed lead to disease onset or an organism dysfunction. WHO estimate that more than 2 billion humans are affected by hidden hunger. Scientific studies show that these ills cause serious problems for pregnant women, elderly and children. Thus, the micronutrients in a normal diet comes up the news opportunities for pharmaceuticals industries as well as vitamin supplements. Pharmaceutical industry is the most innovative company in healthcare. Launcher a blockbuster as a new product through of radical innovation is so hard and with higher costs. In this sense, the micronutrients are an attractive alternative of innovation for pharmaceutical industries with limited financial resources. So, pharmaceutical supplements appear as an incremental innovation of known chemical substances

Internal solitary waves in the Red Sea : an unfolding mystery

Author Posting. © The Oceanography Society, 2012. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 25, no. 2 (2012): 96-107, doi:10.5670/oceanog.2012.45.The off-shelf region between 16.0° and 16.5°N in the southern Red Sea is identified as a new hotspot for the occurrence of oceanic internal solitary waves. Satellite observations reveal trains of solitons that, surprisingly, appear to propagate from the center of the Red Sea, where it is deepest, toward the continental shelf, but they do not survive as coherent structures over the shelf. These solitons are characterized by coherent crest lengths exceeding 80 km and crest-to-crest distances of more than 2 km, compatible with signatures of large-amplitude solitary waves. Despite the fact that these Red Sea solitons have large amplitudes, they appear to be generated by very weak surface tides. Tidal current velocity is only about 5 cm s–1 over the shelf, much weaker than over other ocean shelves where similar solitary waves have been reported. The appearance of these waves over this particular geographical stretch suggests generation by a locally amplified internal tide on the main pycnocline. We consider three possible explanations for soliton generation in the Red Sea: interfacial tide resonance, local generation by internal tidal beams generated at the shelf breaks, and local generation by internal tidal beams generated at the shelf breaks but first amplified by repeated focusing reflections

Toward intelligent cyber-physical systems: Digital twin meets artificial intelligence

Industry 4.0 aims to support smarter and autonomous processes while improving agility, cost efficiency, and user experience. To fulfill its promises, properly processing the data of the industrial processes and infrastructures is required. Artificial intelligence (AI) appears as a strong candidate to handle all generated data, and to help in the automation and smartification process. This article overviews the digital twin as a true embodiment of a cyber-physical system (CPS) in Industry 4.0, showing the mission of AI in this concept. It presents the key enabling technologies of the digital twin such as edge, fog, and 5G, where the physical processes are integrated with the computing and network domains. The role of AI in each technology domain is identified by analyzing a set of AI agents at the application and infrastructure levels. Finally, movement prediction is selected and experimentally validated using real data generated by a digital twin for robotic arms with results showcasing its potential.This work has been (partially) funded by the H2020 EU/TW joint action 5G-DIVE (Grant #859881) and the H2020 5Growth project (Grant #856709). It has also been funded by the Spanish State Research Agency (TRUE5G project, PID2019-108713RB-C52/AEI/10.13039/501100011033)

SINAIS E SINTOMAS EM PACIENTES INTERNADOS POR SARS-COV-2 E AS CONSEQUÊNCIAS DEIXADAS APÓS ALTA MÉDICA: REVISÃO INTEGRATIVA

The Coronavirus is a virus that generated a pandemic with a high morbidity and mortality rate, thus, it becomes important to study the signs and symptoms and post-covid-19 consequences caused by the virus, so that the multiprofessional team can establish efficient care parameters in the treatment of the disease. The objective of the research then was to analyze the scientific evidence about the signs and symptoms in patients hospitalized for Sars-CoV-2 and the consequences left by Sars-Cov-2 after medical discharge. The present study is a literature review by the integrative literature review method, quantitative and exploratory in online databases. The search for the material was done through the PICo strategy. The data analysis was done through detailed reading of the content of the articles categorized by similarity/semantics. When the selection of the studies was performed, 13 publications were refined according to the study objectives and inclusion and exclusion criteria, distributed in different journals. It can be concluded that the coronavirus causes signs and symptoms in a multisystemic way, and can affect the central and peripheral nervous system and the cardiovascular system, but it is more frequent in the respiratory system, since it is a virus that directly affects the upper airways.  El Coronavirus es un virus que generó una pandemia con alta morbilidad y mortalidad, por lo que se hace importante el estudio de los signos y síntomas y las consecuencias postcovídicas causadas por el virus, para que el equipo multiprofesional establezca parámetros de atención eficientes en el tratamiento de la enfermedad. El objetivo de la investigación fue entonces analizar la evidencia científica sobre los signos y síntomas en pacientes hospitalizados por Sars-CoV-2 y las consecuencias que deja el Sars-Cov-2 tras el alta médica. El presente estudio es una revisión bibliográfica mediante el método de revisión integradora de la literatura, cuantitativa y exploratoria en bases de datos en línea. La búsqueda del material se realizó mediante la estrategia PICo. El análisis de los datos se realizó mediante la lectura detallada del contenido de los artículos clasificados por similitud/semántica. Al realizar la selección de los estudios, se depuraron 13 publicaciones según los objetivos del estudio y los criterios de inclusión y exclusión, distribuidas en diferentes revistas. Se puede concluir que el coronavirus provoca signos y síntomas de forma multisistémica, pudiendo alcanzar el sistema nervioso central y periférico, el sistema cardiovascular, pero siendo más frecuente en el sistema respiratorio, por ser un virus que alcanza directamente las vías respiratorias superiores. Palabras clave: signos y síntomas, sars-cov-2, consecuencias post-covid-19.O Coronavírus é um vírus que gerou uma pandemia com alta taxa de morbimortalidade, assim, torna-se importante o estudo dos sinais e sintomas e consequências pós-covid-19 causadas pelo vírus, para que a equipe multiprofissional estabeleça parâmetros de atendimento eficientes no tratamento da doença. O objetivo da pesquisa então foi analisar as evidências científicas acerca dos sinais e sintomas em pacientes internados por Sars-CoV-2 e as consequências deixadas pelo Sars-Cov-2 após alta médica. O presente estudo trata-se de uma revisão bibliográfica pelo método revisão integrativa de literatura, quantitativa e exploratória nas bases de dados on-line. A busca do material foi feita através da estratégia PICo. A análise dos dados foi feita através de leitura detalhada do conteúdo dos artigos categorizados por similaridade/semântica. Quando realizado a seleção dos estudos obteve-se 13 publicações refinadas de acordo com os objetivos do estudo e critérios de inclusão e exclusão, distribuídas em diferentes periódicos. Pode-se concluir que o coronavírus causa sinais e sintomas de forma multissistêmica, podendo atingir o sistema nervoso central e periférico, cardiovascular, mas sendo mais frequente no sistema respiratório, por ser um vírus que atinge diretamente as vias aéreas superiores. Palavras-chave: sinais e sintomas, sars-cov-2, consequências pós-covid-19

Consumption, housing and financial wealth, asset returns, and monetary policy.

This work analyzes the linkages between consumption, housing and financial wealth, asset returns, and monetary policy. In Chapter I, I show, from the consumer's budget constraint, that the residuals of the trend relationship among consumption, financial wealth, housing wealth and labor income, cday, should better predict stock returns than a variable like cay from Lettau and Ludvigson (2001), and that this is due to: (i) the ability to track changes in the wealth composition; and (ii) the faster rate of convergence of the coefficients to the "long-run equilibrium" parameters. In Chapter II, I analyze the empirical relationship between wealth shocks and portfolio composition, and find evidence consistent with counter-cyclical risk aversion. I also show that: (i) there is no evidence of inertia; and (ii) time-variation in expectations about future returns partially explains changes in the risky asset share. In Chapter III, I show that monetary policy contractions have a large and negative impact on housing prices, although the reaction is extremely slow. On the contrary, the effect on stock markets is small and very quick. In Chapter IV, I analyze the importance of the risks for the long-run, and show that they explain a large fraction of the cross-sectional variation of average returns. I also find that the preference for a smooth path of consumption, a low intertemporal elasticity of substitution, and a high risk aversion, imply that agents demand large equity risk premia when they fear a reduction in economic prospects. In Chapter V, I investigate the role of three major sources of risk: future changes in the housing consumption share, cr, future labour income growth, Ir, and future consumption growth, Irc. I show that the predictability of many empirical proxies can be achieved without relying on a specific functional form for consumer's preferences

New boundary conditions for simulating the filling stage of the injection molding process

Purpose The purpose of this paper is to develop new boundary conditions for simulating the injection molding process of polymer melts. Design/methodology/approach The boundary conditions are derived and implemented to simulate real-life air vents (used to allow the air escape from the mold). The simulations are performed in the computational libraryOpenFOAM (R) by considering two different fluid models, namely, Newtonian and generalized Newtonian (Bird-Carreau model). Findings A detailed study on the accuracy of the solverinterFoamfor simulating the filling stage is presented, by considering simple geometries and adaptive mesh refinement. The verified code is then used to study the three-dimensional filling of a more complex geometry. Originality/value The results obtained showed that the numerical method is stable and allows one to model the filling process, simulating the real injection molding process.This work is funded by FEDER funds through the COMPETE 2020 Programme and National Funds through FCT (Portuguese Foundation for Science and Technology) under the projects UID-B/05256/2020, UID-P/05256/2020 and MOLDPRO-Aproximacoes multi-escala para moldacao por injecao de materiais plasticos (POCI-01-0145-FEDER-016665).The research of L.L. Ferras was partially financed by the Portuguese Funds through FCT within the Projects UID-B/00013/2020, UID-P/00013/2020 and the scholarship SFRH/BPD/100353/2014.The authors would like to acknowledge the Minho University Cluster (NORTE-07-0162-FEDER-000086) for providing the HPC resources that contributed to the research results reported within this paper