Bagaço de uva como aditivo natural em carne suína

Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciado em Ciências da NutriçãoIntrodução: Os subprodutos da indústria vitivinícola nacional, embora subvalorizados, constituem uma fonte de compostos bioativos, potenciando-os como aditivos naturais. Reduzir a perda e o desperdício de alimentos é um dos grandes desafios para a reciclagem de recursos naturais e para o avanço de sistemas alimentares sustentáveis. Por outro lado, a segurança alimentar está associada com a promoção da saúde pública, e as necessidades proteicas ideais são um tema de grande interesse para atletas de alta competição. A carne súna é uma excelente fonte de nutrientes e é um tipo de carne que quando consumida sem processamento industrial pode fazer parte de uma dieta saudável. Objetivo: Avaliar o perfil fenólico e quantificar o teor de fenólicos, flavonoides e antocianinas totais de dois bagaços de castas portuguesas (Touriga Nacional e Alvarinho), potenciando-os como aditivos naturais e/ingredientes funcionais em carne suína. Metodologia: O teor de compostos bioativos foram obtidos através de determinações colorimétricas e, para a avaliação do perfil fenólico recorreu-se à cromatografia líquida de alta resolução em fase reversa, acoplado com detetor de díodos (RP-HPLC-DAD). Resultados: Os bagaços apresentaram teores elevados de fenólicos e flavonoides totais (25-41 mg EAG/ g e 9,2-18 mg EC/ g, respetivamente). O teor de antocianinas foi evidenciado no bagaço de uva tinta (37 mg/ g), bem como a presença dos ácidos vanílico e siríngico. A quercetina foi encontrada apenas na casta branca, reforçando o seu potencial como aditivo, uma vez que este flavonoide apresenta propriedades antioxidantes, antinflamatórias, antidiabéticas e antimicrobianas. Conclusão: A presença de compostos bioativos nos bagaços comprovam a importância do reaproveitamento destes subprodutos, evidenciando-os como potenciais ingrediente e/ou aditivos naturais em carnes suínas.Introduction: The byproducts of the national wine industry, although undervalued, constitute a source of bioactive compounds, enhancing them as natural additives. Reducing food loss and waste is one of the great challenges for recycling natural resources and advancing sustainable food systems. On the other hand, food safety is associated with the promotion of public health, and optimal protein requirements are a topic of great interest to top-level athletes. Pork meat is an excellent source of nutrients and it is a kind of meat that, when consumed without industrial processing, can be part of a healthy diet. Objective: Evaluation of the phenolic profile and quantification of the total content of phenolics, flavonoids and anthocyanins of two pomaces from Portuguese grape varieties (Touriga Nacional and Alvarinho), enhancing them as natural additive and/or functional ingredient in pork meat. Methodology: Bioactive compounds quantification were obtained through colorimetric analysis and, for the phenolic profile, a reversed-phase high performance liquid chromatography coupled with a diode detector (RP-HPLC-DAD) was used. Results: Both pomaces showed high levels of phenolics and total flavonoids (25-41 mg GAE/ g and 9.2-18 mg CE/ g, respectively). As expected, the anthocyanin content was evidenced in the red grape pomace (37 mg/ g), as well as the presence of vanillic and syringic acids. Quercetin was found only in white grape varieties, reinforcing the interest of white grape byproducts, since this flavonoid possess antioxidant, anti-inflammatory, antidiabetic and antimicrobial properties. Conclusion: The presence of nutrients and bioactive compounds in grape pomaces proves the importance of being reutilize, as a low-cost raw material, as well as a valuable ingredient and/or additive, proving to be an advantage in their incorporation in pork meat products.N/

MAMMALS IN PORTUGAL : A data set of terrestrial, volant, and marine mammal occurrences in P ortugal

Mammals are threatened worldwide, with 26% of all species being includedin the IUCN threatened categories. This overall pattern is primarily associatedwith habitat loss or degradation, and human persecution for terrestrial mam-mals, and pollution, open net fishing, climate change, and prey depletion formarine mammals. Mammals play a key role in maintaining ecosystems func-tionality and resilience, and therefore information on their distribution is cru-cial to delineate and support conservation actions. MAMMALS INPORTUGAL is a publicly available data set compiling unpublishedgeoreferenced occurrence records of 92 terrestrial, volant, and marine mam-mals in mainland Portugal and archipelagos of the Azores and Madeira thatincludes 105,026 data entries between 1873 and 2021 (72% of the data occur-ring in 2000 and 2021). The methods used to collect the data were: live obser-vations/captures (43%), sign surveys (35%), camera trapping (16%),bioacoustics surveys (4%) and radiotracking, and inquiries that represent lessthan 1% of the records. The data set includes 13 types of records: (1) burrowsjsoil moundsjtunnel, (2) capture, (3) colony, (4) dead animaljhairjskullsjjaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8),observation in shelters, (9) photo trappingjvideo, (10) predators dietjpelletsjpine cones/nuts, (11) scatjtrackjditch, (12) telemetry and (13) vocalizationjecholocation. The spatial uncertainty of most records ranges between 0 and100 m (76%). Rodentia (n=31,573) has the highest number of records followedby Chiroptera (n=18,857), Carnivora (n=18,594), Lagomorpha (n=17,496),Cetartiodactyla (n=11,568) and Eulipotyphla (n=7008). The data setincludes records of species classified by the IUCN as threatened(e.g.,Oryctolagus cuniculus[n=12,159],Monachus monachus[n=1,512],andLynx pardinus[n=197]). We believe that this data set may stimulate thepublication of other European countries data sets that would certainly contrib-ute to ecology and conservation-related research, and therefore assisting onthe development of more accurate and tailored conservation managementstrategies for each species. There are no copyright restrictions; please cite thisdata paper when the data are used in publications.info:eu-repo/semantics/publishedVersio

COOPEDU IV — Cooperação e Educação de Qualidade

O quarto Congresso Internacional de Cooperação e Educação-IV COOPEDU, organizado pelo Centro de Estudos Internacionais (CEI) do Instituto Universitário de Lisboa e pela Escola Superior de Educação e Ciências Sociais do Instituto Politécnico de Leiria decorreu nos dias 8 e 9 de novembro de 2018, subordinado à temática Cooperação e Educação de Qualidade. Este congresso insere-se numa linha de continuidade de intervenção por parte das duas instituições organizadoras e dos elementos coordenadores e este ano beneficiou do financiamento do Instituto Camões, obtido através de um procedimento concursal, que nos permitiu contar com a participação presencial de elementos dos Países Africanos de Língua Portuguesa, fortemente implicados nas problemáticas da Educação e da Formação. Contou também com a participação do Instituto Camões e da Fundação Calouste Gulbenkian, entidades que sistematizaram a sua intervenção nos domínios da cooperação na área da educação nos últimos anos. A opção pela temática da qualidade pareceu aos organizadores pertinente e actual. Com efeito os sistemas educativos dos países que constituem a Comunidade de países de língua portuguesa têm implementado várias reformas mas em vários domínios mantem-se a insatisfação de responsáveis políticos, pedagogos, técnicos sociais face aos resultados obtidos. Aliás o caminho de procura da Qualidade é interminável porque vai a par da aposta na exigência e na promoção da cidadania e responsabilidade social. As comunicações que agora se publicam estão organizadas em dois eixos: o das Políticas da Educação e Formação e o das dimensões em que se traduzem essas políticas. Neste último eixo encontramos fios condutores para agregarmos as comunicações apresentadas

Mammals in Portugal: a data set of terrestrial, volant, and marine mammal occurrences in Portugal

Mammals are threatened worldwide, with ~26% of all species being included in the IUCN threatened categories. This overall pattern is primarily associated with habitat loss or degradation, and human persecution for terrestrial mammals, and pollution, open net fishing, climate change, and prey depletion for marine mammals. Mammals play a key role in maintaining ecosystems functionality and resilience, and therefore information on their distribution is crucial to delineate and support conservation actions. MAMMALS IN PORTUGAL is a publicly available data set compiling unpublished georeferenced occurrence records of 92 terrestrial, volant, and marine mammals in mainland Portugal and archipelagos of the Azores and Madeira that includes 105,026 data entries between 1873 and 2021 (72% of the data occurring in 2000 and 2021). The methods used to collect the data were: live observations/captures (43%), sign surveys (35%), camera trapping (16%), bioacoustics surveys (4%) and radiotracking, and inquiries that represent less than 1% of the records. The data set includes 13 types of records: (1) burrows | soil mounds | tunnel, (2) capture, (3) colony, (4) dead animal | hair | skulls | jaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8), observation in shelters, (9) photo trapping | video, (10) predators diet | pellets | pine cones/nuts, (11) scat | track | ditch, (12) telemetry and (13) vocalization | echolocation. The spatial uncertainty of most records ranges between 0 and 100 m (76%). Rodentia (n =31,573) has the highest number of records followed by Chiroptera (n = 18,857), Carnivora (n = 18,594), Lagomorpha (n = 17,496), Cetartiodactyla (n = 11,568) and Eulipotyphla (n = 7008). The data set includes records of species classified by the IUCN as threatened (e.g., Oryctolagus cuniculus [n = 12,159], Monachus monachus [n = 1,512], and Lynx pardinus [n = 197]). We believe that this data set may stimulate the publication of other European countries data sets that would certainly contribute to ecology and conservation-related research, and therefore assisting on the development of more accurate and tailored conservation management strategies for each species. There are no copyright restrictions; please cite this data paper when the data are used in publications

Phenolic profile from the pomace of two portuguese grape varieties: sustainability and food safety as new natural additives

Grapes are one of the most produced fruit crops worldwide. About 75% of produced grapes is planned for wine production, originating 20-30% waste products. This waste is mainly constituted by grape pomace which includes fruit peels, remaining pulp, seeds, and stalks. Moreover, as it is common knowledge that therapeutic properties of plants and their by-products have been increasingly described, because of their strong antioxidant values, absence of side effects, and economic viability. Synthetic antioxidants have been used as supplement added, however, their inclusion in chronic infections have confined their utilization in foods. Grape pomaces have biotechnological potential, having been applied in several studies as a fortification ingredient in foods. Reuse of the grape pomace depends on its composition and characteristics. Because grape pomace is a highly perishable product (due to the high moisture content) and given the high volumes generated during harvest season, the utilization of fresh grape pomace is unfeasible and requires an appropriate method of preservation or appropriate use. Thus, grape pomace can be reused through oil extraction, antioxidant, and antibacterial agents’ preparation and, from a nutritional perspective, polyphenols are the most important constituents. Large amounts of the residual quantities of bioactive substances remain in the vegetable tissues: phenolic acids, several flavonoids, flavanols (e.g., catechin, epicatechin and epigallocatechin) and other phenolic compounds (proanthocyanidins or condensed tannins). Considering the importance of winemaking in Portugal, the phenolic profile of two national grape pomace varieties (Touriga Nacional (red) e Alvarinho (white)) was studied, considering that the extraction of polyphenols from grape pomace represents an attractive, sustainable, and cost-effective source of high-value biological properties, which could be incorporated into foods, as natural additives. Due to the increasing demand for nutraceutical and antioxidant compounds, the study of grape pomace polyphenols exploitation may be useful for industrial purposes. Phenolic compounds were identified and quantified by Reverse-Phase High Performance Liquid Chromatography (RP HPLC) equipped with a diode array detector (HPLC-DAD).info:eu-repo/semantics/publishedVersio

Nutraceuticals based on portuguese grape pomaces as a potential additive in food products

Portuguese wine industry by-products are often undervalued but constitute a potential source of bioactive phenoliccompounds that can be applied as a natural additive in several industries. In this context, the present study aimed to evaluate the nutritional composition, and the phenolic profile of two Portuguese Vitis vinifera L. grape pomaces (Touriga Nacional (red variety) and Alvarinho (white variety), and to correlate their chemical characterizations with their antioxidant activities. Strong correlations were observed between the presence of phenolic compounds and antioxidant activities, which enhances the application of pomace extracts in food and pharmaceutical areas. The high content of total phenolic compounds (25 - 41 g/ kg dry extract) and of flavonoids (9.2 - 18 g/ kg dry extract) found in both samples make these pomaces excellent candidates as food additives in food products, as well as antioxidant agents, such as natural dyes. Some polyphenols were identified by High Performance Liquid Chromatography (HPLC), being rutin and catequin the highest compounds found in red grape pomace (Touriga Nacional) while quercetin was only quantified in white grape pomace (Alvarinho). Cis-resveratrol was quantified in both grape pomace, which opens horizons for its use since this compound has considerable chemopreventive effects in the three main gains of carcinogenesis. As expected, the anthocyanin content was significantly higher in red grape pomace (37 g/ kg dry extract), emphasizing its interest as a natural food additive. Based on the findings, it is possible to conclude that these by-products have additional value, making them potentially useful in the food, pharmaceutical, and cosmetic industries.info:eu-repo/semantics/publishedVersio

Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection

Regeneration of adult mammalian central nervous system (CNS) axons is abortive, resulting in inability to recover function after CNS lesion, including spinal cord injury (SCI). Here, we show that the spiny mouse (Acomys) is an exception to other mammals, being capable of spontaneous and fast restoration of function after severe SCI, re-establishing hind limb coordination. Remarkably, Acomys assembles a scarless pro-regenerative tissue at the injury site, providing a unique structural continuity of the initial spinal cord geometry. The Acomys SCI site shows robust axon regeneration of multiple tracts, synapse formation, and electrophysiological signal propagation. Transcriptomic analysis of the spinal cord following transcriptome reconstruction revealed that Acomys rewires glycosylation biosynthetic pathways, culminating in a specific pro-regenerative proteoglycan signature at SCI site. Our work uncovers that a glycosylation switch is critical for axon regeneration after SCI and identifies beta 3gnt7, a crucial enzyme of keratan sulfate biosynthesis, as an enhancer of axon growth.Santa Casa da Misericordia de Lisboa MC-39-2019, Wings for Life WFL-PT-21/20, Portuguese Foundation for Science and Technology UID/BIM/04773/2013/CBMRinfo:eu-repo/semantics/publishedVersio

O Compadre Governador: redes de compadrio em Vila Rica de fins do século XVIII

Analisamos neste artigo as relações políticas e sociais formalizadas no sacramento de batismo entre os membros da elite vilarriquenha, no período de 1777-1789. Para tanto, escolhemos os registros de batismo da paróquia de Nossa Senhora do Pilar do Ouro Preto e de suas capelas filiais, como testemunhos do estabelecimento e renovação dos laços de compadrio.<br>We analyze in this study the political and social hierarchic relations, recognized in the baptism sacrament established by Vila Rica de Ouro Preto (Minas Gerais, Brazil) society partners from 1770-1789. To do this we chose the baptism certificates of the Our Lady of Pilar Church and their branch Chapels as testimony of the godparentage relations established and renovated at the baptisms