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A vision-based method for on-road truck height measurement in proactive prevention of collision with overpasses and tunnels
This is the accepted manuscript. The final version is available from Elsevier at http://www.sciencedirect.com/science/article/pii/S0926580514002167.Over-height trucks are continuously striking low clearance overpasses and tunnels. This has led to significant damage, fatalities, and inconvenience to the public. Smart systems can automatically detect and warn oversize trucks, and have been introduced to provide the trucks with the opportunity to avoid a collision. However, high cost of implementing these systems remains a bottleneck for their wide adoption. This paper evaluates the feasibility of using computer vision to detect over-height trucks. In the proposed method, video streams are collected from a surveillance camera attached on the overpass/tunnel, and processed to measure truck heights. The height is measured using line detection and blob tracking which locate upper and lower points of a truck in pixel coordinates. The pixel coordinates are then translated into 3D world coordinates. Proof-of-concept experiment results signify the high performance of the proposed method and its potential in achieving cost-effective monitoring of over-height trucks in the transportation system. The limitations and considerations of the method for field implementation are also discussed.This material is based upon work supported by West Virginia University, Myongji University, and University of Cambridge
Staged and non-staged anaerobic filters : microbial activity segregation, hydrodynamic behaviour and performance
This work describes a comparative study of staged and non-staged anaerobic flters for treating a synthetic dairy waste under similar operating conditions.
The effect of increasing the substrate concentration from 3 to 12 g COD dmˉ³ at a constant hydraulic residence time (HRT) of 2 days was evaluated with
respect to overall reactor performance, biogas production, volatile fatty acids
profiles along the height, methanogenic and acidogenic activity distribution, and
hydrodynamic behaviour. The potential maximum specific methanogenic activity
against acetate, hydrogen, propionate and butyrate and the lactose specific activity
were determined for sludge sampled from three different points in each
reactor, under two operating conditions (influent COD of 3 and 9 g COD
dmˉ³). Although all trophic groups involved in the anaerobic process were
found throughout the reactors, it was possible to identify different specific
sludges at different heights in both reactors. Performances of the two configurations
were very similar under the operating conditions tested and the plug flow
behaviour of the staged reactor was clearly reduced when the influent concentration
increased from 3 to 9 g COD dmˉ³.EU Human Capital and Mobility network Improved Application of Anaerobic
Digestion Technology - EXBCHRXCT 930262.Fundação para a Ciência e a Tecnologia – PEAM/SEL/517/95
Temporomandibular joint prosthesis in cancer reconstruction preceding radiation therapy
Total joint prostheses are a viable treatment option after removal of malignancies invading the temporomandibular joint, even when adjuvant radiation therapy is required.publishedVersio
Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies
PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
The role of mutation rate variation and genetic diversity in the architecture of human disease
Background
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified.
Results
Consistent with our predictions we find that genes associated with Mendelian and complex disease are substantially longer than non-disease genes. However, we find that both Mendelian and complex disease genes are found in regions of the genome with relatively low mutation rates, as inferred from intron divergence between humans and chimpanzees, and they are predicted to have similar rates of non-synonymous mutation as other genes. Finally, we find that disease genes are in regions of significantly elevated genetic diversity, even when variation in the rate of mutation is controlled for. The effect is small nevertheless.
Conclusions
Our results suggest that gene length contributes to whether a gene is associated with disease. However, the mutation rate and the genetic architecture of the locus appear to play only a minor role in determining whether a gene is associated with disease
Institutional Export Barriers on Exporters from Emerging Markets: Evidence from China
The emerging markets have become the increasingly important trading nations in the global economy. Given its significance to practitioners and policymakers, export barriers has been the popular topic in the international business studies. However, research about export barriers caused by the local institutions are under developed, though institutional voids and institutional inefficiency are reported as the major determinants for business development in emerging markets. This paper aims to fill in this gap by exploring the institutional export barriers in emerging markets. Based on existing studies on export barriers and institutional perspective, a conceptual framework is initially developed by separating formal and informal institutional export barriers. Then three specific institutional export barriers are identified, including government policy, weak legal system and informal and personal networks. In the meanwhile, this paper sheds light on how the institutional export barriers are developed and obstruct exporting in emerging markets
Complete chloroplast genome sequence of Holoparasite Cistanche Deserticola (Orobanchaceae) reveals gene loss and horizontal gene transfer from Its host Haloxylon Ammodendron (Chenopodiaceae)
The central function of chloroplasts is to carry out photosynthesis, and its gene content and structure are highly conserved across land plants. Parasitic plants, which have reduced photosynthetic ability, suffer gene losses from the chloroplast (cp) genome accompanied by the relaxation of selective constraints. Compared with the rapid rise in the number of cp genome sequences of photosynthetic organisms, there are limited data sets from parasitic plants. The authors report the complete sequence of the cp genome of Cistanche deserticola, a holoparasitic desert species belonging to the family Orobanchaceae
Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer
Development of a Mesoamerican intra-genepool genetic map for quantitative trait loci detection in a drought tolerant × susceptible common bean (Phaseolus vulgaris L.) cross
Drought is a major constraint to common bean (Phaseolus vulgaris L.) production, especially in developing countries where irrigation for the crop is infrequent. The Mesoamerican genepool is the most widely grown subdivision of common beans that include small red, small cream and black seeded varieties. The objective of this study was to develop a reliable genetic map for a Mesoamerican × Mesoamerican drought tolerant × susceptible cross and to use this map to analyze the inheritance of yield traits under drought and fully irrigated conditions over 3 years of experiments. The source of drought tolerance used in the cross was the cream-seeded advanced line BAT477 crossed with the small red variety DOR364 and the population was made up of recombinant inbred lines in the F5 generation. Quantitative trait loci were detected by composite interval mapping for the traits of overall seed yield, yield per day, 100 seed weight, days to flowering and days to maturity for each field environment consisting of two treatments (irrigated and rainfed) and lattice design experiments with three repetitions for a total of six environments. The genetic map based on amplified fragment length polymorphism and random amplified polymorphic DNA markers was anchored with 60 simple sequence repeat (SSR) markers and had a total map length of 1,087.5 cM across 11 linkage groups covering the whole common bean genome with saturation of one marker every 5.9 cM. Gaps for the genetic map existed on linkage groups b03, b09 and b11 but overall there were only nine gaps larger than 15 cM. All traits were inherited quantitatively, with the greatest number for seed weight followed by yield per day, yield per se, days to flowering and days to maturity. The relevance of these results for breeding common beans is discussed in particular in the light of crop improvement for drought tolerance in the Mesoamerican genepool
Acupuncture for chronic low back pain: protocol for a multicenter, randomized, sham-controlled trial
<p>Abstract</p> <p>Background</p> <p>Use of acupuncture has widely increased in patients with chronic low back pain. However, the evidence supporting its efficacy remains unclear. In this article, we report the design and the protocol of a multi-center randomized sham-controlled trial to treat chronic low back pain. Our goal is to verify the effect of acupuncture on chronic low back pain.</p> <p>Methods/Design</p> <p>This study is a multi-center randomized sham-controlled trial with 2 parallel arms. Participants included in the study met the following criteria: 1) low back pain lasting for at least the last 3 months, 2) a documented ≥ 5 points on a 10 cm visual analog scale for bothersomeness of low back pain at the time of screening and 3) between 18 and 65 years of age. Participants were blinded to the real and sham acupuncture treatments. The real acupuncture treatment group received real acupuncture 2 times a week, during a total of 12 sessions over 6 weeks. The control group received sham acupuncture during the same period. In order to assess the primary and secondary outcome measures, the participants were asked to fill out a questionnaire at the baseline and 6, 8, 12 and 24 weeks after starting the treatments. The primary outcome was measured using the visual analog scale for bothersomeness of low back pain at 8 weeks after the initiation of treatments.</p> <p>Discussion</p> <p>The result of this trial (which will be available in 2010) will demonstrate the efficacy of using acupuncture to treat chronic low back pain.</p> <p>Trial registration</p> <p>This study is registered with the U.S. National Institutes of Health Clinical Trials registry: NCT00815529</p
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