1,173 research outputs found

    Perceptual Compressive Sensing

    Full text link
    Compressive sensing (CS) works to acquire measurements at sub-Nyquist rate and recover the scene images. Existing CS methods always recover the scene images in pixel level. This causes the smoothness of recovered images and lack of structure information, especially at a low measurement rate. To overcome this drawback, in this paper, we propose perceptual CS to obtain high-level structured recovery. Our task no longer focuses on pixel level. Instead, we work to make a better visual effect. In detail, we employ perceptual loss, defined on feature level, to enhance the structure information of the recovered images. Experiments show that our method achieves better visual results with stronger structure information than existing CS methods at the same measurement rate.Comment: Accepted by The First Chinese Conference on Pattern Recognition and Computer Vision (PRCV 2018). This is a pre-print version (not final version

    Quantifying the burden of rhodesiense sleeping sickness in Urambo district, Tanzania

    Get PDF
    Sleeping sickness (human African trypanosomiasis - HAT) is a disease transmitted by tsetse flies and is always fatal if left untreated. The disease occurs in foci affecting poor communities with limited access to health service provision and as such the disease is often left undiagnosed, mistaken for more common afflictions. Even if diagnosed, sleeping sickness is costly to treat, both for health services and patients and their families in terms of costs of diagnosis, transport, hospital care, and the prolonged period of convalescence. Here we estimate the health burden of the acute form T. b. rhodesiense sleeping sickness in Urambo District, Tanzania in terms of Disability Adjusted Life Years (DALYs), the yardstick commonly used by policy makers to prioritize disease management practices, representing a year of healthy life lost to disease. In this single district, the burden of the disease over one year was estimated at 979 DALYs and the estimated monetary costs to health services for the 143 treated patients at US11,841andtothepatientsthemselvesatUS 11,841 and to the patients themselves at US 3,673 for direct medical costs and US$ 9,781 for indirect non-medical costs. Sleeping sickness thus places a considerable burden on the affected rural communities and health services

    The effects of socioeconomic status and indices of physical environment on reduced birth weight and preterm births in Eastern Massachusetts

    Get PDF
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: Air pollution and social characteristics have been shown to affect indicators of health. While use of spatial methods to estimate exposure to air pollution has increased the power to detect effects, questions have been raised about potential for confounding by social factors.Methods: A study of singleton births in Eastern Massachusetts was conducted between 1996 and 2002 to examine the association between indicators of traffic, land use, individual and area-based socioeconomic measures (SEM), and birth outcomes ( birth weight, small for gestational age and preterm births), in a two-level hierarchical model.Results: We found effects of both individual ( education, race, prenatal care index) and area-based ( median household income) SEM with all birth outcomes. The associations for traffic and land use variables were mainly seen with birth weight, with an exception for an effect of cumulative traffic density on small for gestational age. Race/ethnicity of mother was an important predictor of birth outcomes and a strong confounder for both area-based SEM and indices of physical environment. The effects of traffic and land use differed by level of education and median household income.Conclusion: Overall, the findings of the study suggested greater likelihood of reduced birth weight and preterm births among the more socially disadvantaged, and a greater risk of reduced birth weight associated with traffic exposures. Results revealed the importance of controlling simultaneously for SEM and environmental exposures as the way to better understand determinants of health.This work is supported by the Harvard Environmental Protection Agency (EPA) Center, Grants R827353 and R-832416, and National Institute for Environmental Health Science (NIEHS) ES-0002

    A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.

    Get PDF
    There is great potential for host-based gene expression analysis to impact the early diagnosis of infectious diseases. In particular, the influenza pandemic of 2009 highlighted the challenges and limitations of traditional pathogen-based testing for suspected upper respiratory viral infection. We inoculated human volunteers with either influenza A (A/Brisbane/59/2007 (H1N1) or A/Wisconsin/67/2005 (H3N2)), and assayed the peripheral blood transcriptome every 8 hours for 7 days. Of 41 inoculated volunteers, 18 (44%) developed symptomatic infection. Using unbiased sparse latent factor regression analysis, we generated a gene signature (or factor) for symptomatic influenza capable of detecting 94% of infected cases. This gene signature is detectable as early as 29 hours post-exposure and achieves maximal accuracy on average 43 hours (p = 0.003, H1N1) and 38 hours (p-value = 0.005, H3N2) before peak clinical symptoms. In order to test the relevance of these findings in naturally acquired disease, a composite influenza A signature built from these challenge studies was applied to Emergency Department patients where it discriminates between swine-origin influenza A/H1N1 (2009) infected and non-infected individuals with 92% accuracy. The host genomic response to Influenza infection is robust and may provide the means for detection before typical clinical symptoms are apparent

    Revista de Revistas.

    Get PDF
    Farmacoterapia en el paciente suicida. Pharmacotherapy of the suicidal patient P Kragh-Sorensen Acta Psychiatr Scand 1993: Suppl 371. M. A. Casado Fumar cigarrillos: sus implicaciones en trastornos psiquiátricos. Cigarrette smoking: Implications for psychiatric illness A.H. Glassman Am. J. Psychiatry 1993; 150: 546·553. J. Jáuregui Isasmendi Síndrome de Gilles de la Tourette: un trastorno neuropsiquiátrico. Gilles de la Tourette Syndrome: a neuropsychiatric disorder P Sandor Journal of Psychomatic Research 1993; 37 (3): 211-226. M.T. de Lucas Taracena Curso Clínico de 636 pacientes alcohólicos hospitalizados. M.A. Schuckit, T.L. Smith, R. Anthenelli, M. Irwin American Journal of Psych. May 1993; 150, 5: 786-791. M.1. de la Hera Cabero Pérdida de los efectos del tto. tras terapia continuada. FM. Quitkin, J.W Stewart, PJ. McGrath, E. Nunes, K. Ocepek-Welikson, E. Tricamo, J.G. Rabkin, o. Ross, o.F Klein American Journ. of Psych. April 1993; 150, 4: 562-565. M.I. de la Hera Cabero "Acting out" y temas de transferencia inducidos por sucesivos embarazos de la analista. Acting out and transference themes induced by succesive pregnancies of the analyst M. Deben-Mager. El embarazo de la analista y sus consecuencias sobre su trabajo. The analyst's preganacy and its consequences on her work. A. Etchegoyen. El embarazo de la analista: el paciente, la analista y el espacio de lo desconocido. The analyst's pregnancy: the patient, the analyst and the space of the unknown P Mariotti En The International Journal of Psycho-Analysis. febrero 1993; vol 74, parto 1: pags 129-139, 141-149, 151-164 respectivamente. Escudero Nafs,

    Revista de Revistas.

    Get PDF
    Farmacoterapia en el paciente suicida. Pharmacotherapy of the suicidal patient P Kragh-Sorensen Acta Psychiatr Scand 1993: Suppl 371. M. A. Casado Fumar cigarrillos: sus implicaciones en trastornos psiquiátricos. Cigarrette smoking: Implications for psychiatric illness A.H. Glassman Am. J. Psychiatry 1993; 150: 546·553. J. Jáuregui Isasmendi Síndrome de Gilles de la Tourette: un trastorno neuropsiquiátrico. Gilles de la Tourette Syndrome: a neuropsychiatric disorder P Sandor Journal of Psychomatic Research 1993; 37 (3): 211-226. M.T. de Lucas Taracena Curso Clínico de 636 pacientes alcohólicos hospitalizados. M.A. Schuckit, T.L. Smith, R. Anthenelli, M. Irwin American Journal of Psych. May 1993; 150, 5: 786-791. M.1. de la Hera Cabero Pérdida de los efectos del tto. tras terapia continuada. FM. Quitkin, J.W Stewart, PJ. McGrath, E. Nunes, K. Ocepek-Welikson, E. Tricamo, J.G. Rabkin, o. Ross, o.F Klein American Journ. of Psych. April 1993; 150, 4: 562-565. M.I. de la Hera Cabero "Acting out" y temas de transferencia inducidos por sucesivos embarazos de la analista. Acting out and transference themes induced by succesive pregnancies of the analyst M. Deben-Mager. El embarazo de la analista y sus consecuencias sobre su trabajo. The analyst's preganacy and its consequences on her work. A. Etchegoyen. El embarazo de la analista: el paciente, la analista y el espacio de lo desconocido. The analyst's pregnancy: the patient, the analyst and the space of the unknown P Mariotti En The International Journal of Psycho-Analysis. febrero 1993; vol 74, parto 1: pags 129-139, 141-149, 151-164 respectivamente. Escudero Nafs,

    Time spent outdoors in childhood is associated with reduced risk of myopia as an adult

    Get PDF
    Myopia (near-sightedness) is an important public health issue. Spending more time outdoors can prevent myopia but the long-term association between this exposure and myopia has not been well characterised. We investigated the relationship between time spent outdoors in childhood, adolescence and young adulthood and risk of myopia in young adulthood. The Kidskin Young Adult Myopia Study (KYAMS) was a follow-up of the Kidskin Study, a sun exposure-intervention study of 1776 children aged 6–12 years. Myopia status was assessed in 303 (17.6%) KYAMS participants (aged 25–30 years) and several subjective and objective measures of time spent outdoors were collected in childhood (8–12 years) and adulthood. Index measures of total, childhood and recent time spent outdoors were developed using confirmatory factor analysis. Logistic regression was used to assess the association between a 0.1-unit change in the time outdoor indices and risk of myopia after adjusting for sex, education, outdoor occupation, parental myopia, parental education, ancestry and Kidskin Study intervention group. Spending more time outdoors during childhood was associated with reduced risk of myopia in young adulthood (multivariable odds ratio [OR] 0.82, 95% confidence interval [CI] 0.69, 0.98). Spending more time outdoors in later adolescence and young adulthood was associated with reduced risk of late-onset myopia (≥ 15 years of age, multivariable OR 0.79, 95% CI 0.64, 0.98). Spending more time outdoors in both childhood and adolescence was associated with less myopia in young adulthood

    A Systematic Review of Mosquito Coils and Passive Emanators: Defining Recommendations for Spatial Repellency Testing Methodologies.

    Get PDF
    Mosquito coils, vaporizer mats and emanators confer protection against mosquito bites through the spatial action of emanated vapor or airborne pyrethroid particles. These products dominate the pest control market; therefore, it is vital to characterize mosquito responses elicited by the chemical actives and their potential for disease prevention. The aim of this review was to determine effects of mosquito coils and emanators on mosquito responses that reduce human-vector contact and to propose scientific consensus on terminologies and methodologies used for evaluation of product formats that could contain spatial chemical actives, including indoor residual spraying (IRS), long lasting insecticide treated nets (LLINs) and insecticide treated materials (ITMs). PubMed, (National Centre for Biotechnology Information (NCBI), U.S. National Library of Medicine, NIH), MEDLINE, LILAC, Cochrane library, IBECS and Armed Forces Pest Management Board Literature Retrieval System search engines were used to identify studies of pyrethroid based coils and emanators with key-words "Mosquito coils" "Mosquito emanators" and "Spatial repellents". It was concluded that there is need to improve statistical reporting of studies, and reach consensus in the methodologies and terminologies used through standardized testing guidelines. Despite differing evaluation methodologies, data showed that coils and emanators induce mortality, deterrence, repellency as well as reduce the ability of mosquitoes to feed on humans. Available data on efficacy outdoors, dose-response relationships and effective distance of coils and emanators is inadequate for developing a target product profile (TPP), which will be required for such chemicals before optimized implementation can occur for maximum benefits in disease control
    corecore