11,476 research outputs found

    Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela.

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    OBJECTIVE: Examine whether glycaemic control varies according to sex and whether the latter plays a role in modifying factors associated with inadequate glycaemic control in patients with type 2 diabetes (T2D) in Brazil and Venezuela. DESIGN, SETTING AND PARTICIPANTS: This was a cross-sectional, nationwide survey conducted in Brazil and Venezuela from February 2006 to June 2007 to obtain information about glycaemic control and its determinants in patients with diabetes mellitus attending outpatient clinics. MAIN OUTCOME MEASURES: Haemoglobin A1c (HbA1c) level was measured by liquid chromatography, and patients with HbA1c ≥7.0% (53 mmol/mol) were considered to have inadequate glycaemic control. The association of selected variables with glycaemic control was analysed by multivariate linear regression, using HbA1c as the dependent variable. RESULTS: A total of 9418 patients with T2D were enrolled in Brazil (n=5692) and in Venezuela (n=3726). They included 6214 (66%) women and 3204 (34%) men. On average, HbA1c levels in women were 0.13 (95% CI 0.03 to 0.24; p=0.015) higher than in men, after adjusting for age, marital status, education, race, country, body mass index, duration of disease, complications, type of healthcare, adherence to diet, adherence to treatment and previous measurement of HbA1c. Sex modified the effect of some factors associated with glycaemic control in patients with T2D in our study, but had no noteworthy effect in others. CONCLUSIONS: Women with T2D had worse glycaemic control than men. Possible causes for poorer glycaemic control in women compared with men include differences in glucose homeostasis, treatment response and psychological factors. In addition, sex modified factors associated with glycaemic control, suggesting the need to develop specific treatment guidelines for men and women

    Efficiency of sulfur application on soybean in two types of Oxisols in Southern Brazil.

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    Modern agricultural techniques have been increasing the yield of soybean (Glycine max L.) while also causing increasing removal of sulfur (S) from the soil. Besides this, the use of concentrated fertilizers with this element and inadequate soil management, with consequent formation of organic matter with low S concentrations, has been causing frequent symptoms if deficiency in the plats. To assess the effect of S on soybean yield and to establish critical levels of S-SO42- available in the soil, two experiments were conducted over a two-year period in the Parana State, Brazil, in fields containing Typic Haplorthox and Typic Eutrorthox soils, located in the municipalities of Ponta Grossa and Londrina, respectively. The experimental design was randomized blocks with five S rates (0, 25, 50, 75, and 100 kg ha-1) and four replicates. The source used was elementary S with 98% purity. The maximum estimated yields on average for the two years were obtained with application of 49.9 and 63.0 kg ha-1 in the Typic Haplorthox and Typic Eutrorthox soils, for an overall average of 56.4 kg ha-1, with S-SO42- concentrations in the 0-20 cm depth of 16.9, 19.3 and 17.1 mg kg-1, respectively, values higher than the 10 mg kg-1 indicated as the adequate concentration for soybean plant. In turn, at the 21-40 cm depth, the S concentrations were 49.5, 74.2 and 56.4 kg ha-1. The efficiency of the fertilization diminished with increasing S rates, in both soil types, while the greatest yield efficiency was obtained in the plants grown in the Typic Haplorthox soil

    Morphological transition between diffusion-limited and ballistic aggregation growth patterns

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    In this work, the transition between diffusion-limited and ballistic aggregation models was revisited using a model in which biased random walks simulate the particle trajectories. The bias is controlled by a parameter λ\lambda, which assumes the value λ=0\lambda=0 (1) for ballistic (diffusion-limited) aggregation model. Patterns growing from a single seed were considered. In order to simulate large clusters, a new efficient algorithm was developed. For λ0\lambda \ne 0, the patterns are fractal on the small length scales, but homogeneous on the large ones. We evaluated the mean density of particles ρˉ\bar{\rho} in the region defined by a circle of radius rr centered at the initial seed. As a function of rr, ρˉ\bar{\rho} reaches the asymptotic value ρ0(λ)\rho_0(\lambda) following a power law ρˉ=ρ0+Arγ\bar{\rho}=\rho_0+Ar^{-\gamma} with a universal exponent γ=0.46(2)\gamma=0.46(2), independent of λ\lambda. The asymptotic value has the behavior ρ01λβ\rho_0\sim|1-\lambda|^\beta, where β=0.26(1)\beta= 0.26(1). The characteristic crossover length that determines the transition from DLA- to BA-like scaling regimes is given by ξ1λν\xi\sim|1-\lambda|^{-\nu}, where ν=0.61(1)\nu=0.61(1), while the cluster mass at the crossover follows a power law Mξ1λαM_\xi\sim|1 -\lambda|^{-\alpha}, where α=0.97(2)\alpha=0.97(2). We deduce the scaling relations \beta=\n u\gamma and β=2να\beta=2\nu-\alpha between these exponents.Comment: 7 pages, 8 figure

    Manejo e controle das principais pragas da cultura do arroz irrigado na região do baixo São Francisco.

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    bitstream/item/64533/1/CPATC-DOCUMENTOS-70-MANEJO-E-CONTROLE-DAS-PRINCIPAIS-PRAGAS-DA-CULTURA-DO-ARROZ-IRRIGADO-NA-REGIA.pd

    Musical control gestures in mobile handheld devices: Design guidelines informed by daily user experience

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    Mobile handheld devices, such as smartphones and tablets, have become some of the most prominent ubiquitous terminals within the information and communication technology landscape. Their transformative power within the digital music domain changed the music ecosystem from production to distribution and consumption. Of interest here is the ever-expanding number of mobile music applications. Despite their growing popularity, their design in terms of interaction perception and control is highly arbitrary. It remains poorly addressed in related literature and lacks a clear, systematized approach. In this context, our paper aims to provide the first steps towards defining guidelines for optimal sonic interaction design practices in mobile music applications. Our design approach is informed by user data in appropriating mobile handheld devices. We conducted an experiment to learn links between control gestures and musical parameters, such as pitch, duration, and amplitude. A twofold action—reflection protocol and tool-set for evaluating the aforementioned links—are also proposed. The results collected from the experiment show statistically significant trends in pitch and duration control gesture mappings. On the other hand, amplitude appears to elicit a more diverse mapping approach, showing no definitive trend in this experiment.info:eu-repo/semantics/publishedVersio

    Monovalent counterion distributions at highly charged water interfaces: Proton-transfer and Poisson-Boltzmann theory

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    Surface sensitive synchrotron-X-ray scattering studies reveal the distributions of monovalent ions next to highly charged interfaces. A lipid phosphate (dihexadecyl hydrogen-phosphate) was spread as a monolayer at the air-water interface, containing CsI at various concentrations. Using anomalous reflectivity off and at the L3L_3 Cs+^+ resonance, we provide, for the first time, spatial counterion distributions (Cs+^+) next to the negatively charged interface over a wide range of ionic concentrations. We argue that at low salt concentrations and for pure water the enhanced concentration of hydroniums H3_3O+^+ at the interface leads to proton-transfer back to the phosphate group by a high contact-potential, whereas high salt concentrations lower the contact-potential resulting in proton-release and increased surface charge-density. The experimental ionic distributions are in excellent agreement with a renormalized-surface-charge Poisson-Boltzmann theory without fitting parameters or additional assumptions

    Flood hazard mapping by integrating airborne laser scanning data, high resolution images and large scale maps: a case study

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    The assessment and management of flood risks framework impose the mapping of flood hazard in potential flood risks areas. Floods in urban environments may happen due to rainfall extreme events and be exacerbated by saturated or impervious surfaces. Flood risk is greater in urban areas. (...

    Incorporation of excluded volume correlations into Poisson-Boltzmann theory

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    We investigate the effect of excluded volume interactions on the electrolyte distribution around a charged macroion. First, we introduce a criterion for determining when hard-core effects should be taken into account beyond standard mean field Poisson-Boltzmann (PB) theory. Next, we demonstrate that several commonly proposed local density functional approaches for excluded volume interactions cannot be used for this purpose. Instead, we employ a non-local excess free energy by using a simple constant weight approach. We compare the ion distribution and osmotic pressure predicted by this theory with Monte Carlo simulations. They agree very well for weakly developed correlations and give the correct layering effect for stronger ones. In all investigated cases our simple weighted density theory yields more realistic results than the standard PB approach, whereas all local density theories do not improve on the PB density profiles but on the contrary, deviate even more from the simulation results.Comment: 23 pages, 7 figures, 1 tabl
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