119 research outputs found
Imaging of Early-Stage Cracking on Real-Size Concrete Structure from 4-Points Bending Test
International audienceTraditional ultrasonic imaging techniques encounter difficulty on complexes material such as concrete, which is in part due the use of coherent waves in a very heterogeneous material. From this angle, technique called LOCADIFF has been developed for monitoring heterogeneous media using multiply scattered waves [1, 2]. We consider that modifications in the medium are equivalent to the presence of extra scatterers, which are characterized by their effective scattering cross-section σ,. Within this view, LOCADIFF allows to locate the modification by measuring the spatio-temporal de-correlation of multiply scattered waves and by solving the corresponding inverse problem. Based on LOCADIFF, a newly developed imaging technique has been reported [3]. By mapping the intensity of modification on localized microstructure, the new technique is able to detect perturbations at multiple locations. Here we present the application of this new technique on a real-size 15 tons concrete structure for imaging early-stage cracking procedure issued from four point bending load, as part of the CEOS.fr project. Experimental results show that this technique can not only locate cracks that appeared simultaneously at multiple locations, but also detect them and observe their developments since an early-stage
Towards the evidence of a purely spatial spatial Einstein-Podolsky-Rosen paradox in images: measurement scheme and first experimental results
International audienceWe propose a scheme to evidence the Einstein-Podolsky-Rosen (EPR) paradox for photons produced by spontaneous down conversion, from measurement of purely spatial correlations of photon positions both in the near- and in the far-field. Experimentally, quantum correlations have been measured in the far-field of parametric fluorescence created in a type II BBO crystal. Imaging is performed in the photon counting regime with an electron-multiplying CCD (EMCCD) camera
Sea ice thickness and elastic properties from the analysis of multimodal guided wave propagation measured with a passive seismic array
Field data are needed for a better understanding of sea ice decline in the context of climate change. The rapid technological and methodological advances of the last decade have led to a reconsideration of seismic methods in this matter. In particular, passive seismology has filled an important gap by removing the need to use active sources. We present a seismic experiment where an array of 247 geophones was deployed on sea ice, in the Van Mijen fjord near Sveagruva (Svalbard). The array is a mix of 1C and 3C stations with sampling frequencies of 500 and 1000 Hz. They recorded continuously the ambient seismic field in sea ice between 28 February and 26 March 2019. Data also include active acquisitions on 1 and 26 March with a radar antenna, a shaker unit, impulsive sources, and artificial sources of seismic noise. This data set is of unprecedented quality regarding sea ice seismic monitoring, as it also includes thousands of microseismic events recorded each day. By combining passive seismology approaches with specific array processing methods, we demonstrate that the multimodal dispersion curves of sea ice can be calculated without an active source and then used to infer sea ice properties. We calculated an ice thickness, Young's modulus, and Poisson's ratio with values h=543 cm, E=3.90.15 GPa, and nu=0.340.02 on 1 March, and h=583 cm, E=4.4 +/- 0.15 GPa, and nu=0.32 +/- 0.02 on 5 March. These values are consistent with in situ field measurements and observations.Peer reviewe
SociologĂa pragmática: manual de uso
En treinta años, la “sociologĂa pragmática” (tambiĂ©n denominada “sociologĂa de las pruebas”) ha producido investigaciones empĂricas que abarcan todos los ámbitos de la vida social. De conformidad con los postulados teĂłricos que tenĂan la intenciĂłn de defender, los investigadores que se reconocen en esa corriente sociolĂłgica establecieron formas sensiblemente nuevas de dirigir la investigaciĂłn, recabar datos, explorar campos, pensar por caso y utilizar las controversias y los escándalos como puntos de entrada en el orden social y en la cuestiĂłn de su problemática reproducciĂłn. Este artĂculo tiene por objeto caracterizar en diez puntos el estilo pragmático en sociologĂa y precisar cuáles son sus requisitos metodolĂłgicos y sus consecuencias prácticas en la conducciĂłn del trabajo de investigaciĂłn
Sociologia pragmática: guia do usuário
Em trinta anos, a “sociologia pragmática” (tambĂ©m denominada “sociologia das provas”) efetuou pesquisas empĂricas relativas a todas as áreas da vida social. Em conformidade com os postulados teĂłricos que defendiam, os pesquisadores que se reconhecem nessa corrente sociolĂłgica criaram maneiras consideravelmente novas de efetuar a pesquisa, coletar dados, explorar os campos, pensar cada caso e se servir das controvĂ©rsias e dos escândalos pĂşblicos como pontos de entrada na ordem social e na questĂŁo de sua problemática reprodução. O objetivo deste artigo Ă© caracterizar em dez pontos o estilo pragmático em sociologia e indicar seus requisitos metodolĂłgicos e suas consequĂŞncias práticas para o trabalho de investigação
Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site
Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous antimicrotubule agents are prepared every year, and the determination of their binding affinity to tubulin requires the use of purified tubulins and radiolabeled ligands. Such a procedure is costly and time-consuming and therefore is limited to the most promising candidates. Here, we report a quick and inexpensive method that requires only usual laboratory resources to assess the binding of antimicrotubules to colchicine-binding site. The method is based on the ability of N,N'-ethylene-bis(iodoacetamide) (EBI) to crosslink in living cells the cysteine residues at position 239 and 354 of β-tubulin, residues which are involved in the colchicine-binding site. The β-tubulin adduct formed by EBI is easily detectable by Western blot as a second immunoreacting band of β-tubulin that migrates faster than β-tubulin. The occupancy of colchicine-binding site by pertinent antimitotics inhibits the formation of the EBI: β-tubulin adduct, resulting in an assay that allows the screening of new molecules targeting this binding site
Biomechanical simulations of the scoliotic deformation process in the pinealectomized chicken: a preliminary study
<p>Abstract</p> <p>Background</p> <p>The basic mechanisms whereby mechanical factors modulate the metabolism of the growing spine remain poorly understood, especially the role of growth adaptation in spinal disorders like in adolescent idiopathic scoliosis (AIS). This paper presents a finite element model (FEM) that was developed to simulate early stages of scoliotic deformities progression using a pinealectomized chicken as animal model.</p> <p>Methods</p> <p>The FEM includes basic growth and growth modulation created by the muscle force imbalance. The experimental data were used to adapt a FEM previously developed to simulate the scoliosis deformation process in human. The simulations of the spine deformation process are compared with the results of an experimental study including a group of pinealectomized chickens.</p> <p>Results</p> <p>The comparison of the simulation results of the spine deformation process (Cobb angle of 37°) is in agreement with experimental scoliotic deformities of two representative cases (Cobb angle of 41° and 30°). For the vertebral wedging, a good agreement is also observed between the calculated (28°) and the observed (25° – 30°) values.</p> <p>Conclusion</p> <p>The proposed biomechanical model presents a novel approach to realistically simulate the scoliotic deformation process in pinealectomized chickens and investigate different parameters influencing the progression of scoliosis.</p
Lethal and Sublethal Effects of Single and Double Applications of <I>Bacillus thuringiensis</I> Variety <I>kurstaki</I> on Spruce Budworm (Lepidoptera: Tortricidae) Larvae
Locating structural changes in a multiple scattering domain with an irregular shape
International audienceLocadiff is a method for imaging local structural changes in a random, heterogeneous medium. It relies on the combination of a forward model to calculate the sensitivity kernel of the source-receiver pairs, with an inversion method to determine the position of the changes. So far, the sensitivity kernel has been evaluated based on an analytical solution of the diffusion equation, which lacks the flexibility to handle problems where the domain has boundaries with an irregular shape. Moreover, the accuracy of the previous inversion method, based on linear algebra tools, was very sensitive to the values of the inversion parameters. This paper introduces a more generic approach to solve both these issues. The first problem is tackled by the implementation of numerical method as an alternative for solving the diffusion equation. The second problem is tackled by the introduction of enhanced optimization algorithms to improve the stability of the inversion. This improved version of Locadiff is validated via both numerical examples and experimental data from an actual civil engineering problem
L'introduction de l'immobilier dans un portefeuille institutionnel optimal
Artus Patrick, Flamarion Éric, Moreau Pascale. L'introduction de l'immobilier dans un portefeuille institutionnel optimal . In: Revue d'économie financière. Hors-série, 1993. Numéro Hors-Série : La crise financière de l’immobilier : Réfléxions sur un phénomène mondial Suivi des actes du séminaire Institutional investment in real estate. pp. 409-425
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