ESTIMATION OF EXTERNAL COSTS OF ELECTRICITY GENERATION USING EXTERNE MODEL

The external costs of electricity generation can be characterised by the resulting social and environmental impacts. The most significant impacts are the air pollutions impact on health, built in environment, crops, forests, agricultural areas and on global warming. The primary impact considered is the air pollution’s effect on human health. The monetised value of the health impact, the external costs are calculated for two regional coal power plants, the effects are examined on the EU level with the ExternE methodology.External costs, human health, monetized environmental impacts, energy production, coal power plants, air pollution, Environmental Economics and Policy, Health Economics and Policy, Research Methods/ Statistical Methods,

Geophysical study of the structure and processes of the continental convergence zones: Alpine-Himalayan belt

Studies of the structure of the continental collision zones using seismic and body waves, theoretical modelling of the thermal regime of the convergence processes, and studies of earthquake mechanisms and deformation aspects of the model are covered

Building Damage-Resilient Dominating Sets in Complex Networks against Random and Targeted Attacks

We study the vulnerability of dominating sets against random and targeted node removals in complex networks. While small, cost-efficient dominating sets play a significant role in controllability and observability of these networks, a fixed and intact network structure is always implicitly assumed. We find that cost-efficiency of dominating sets optimized for small size alone comes at a price of being vulnerable to damage; domination in the remaining network can be severely disrupted, even if a small fraction of dominator nodes are lost. We develop two new methods for finding flexible dominating sets, allowing either adjustable overall resilience, or dominating set size, while maximizing the dominated fraction of the remaining network after the attack. We analyze the efficiency of each method on synthetic scale-free networks, as well as real complex networks

Inverse Compton scattering in mildly relativistic plasma

We investigated the effect of inverse Compton scattering in mildly relativistic static and moving plasmas with low optical depth using Monte Carlo simulations, and calculated the Sunyaev-Zel'dovich effect in the cosmic background radiation. Our semi-analytic method is based on a separation of photon diffusion in frequency and real space. We use Monte Carlo simulation to derive the intensity and frequency of the scattered photons for a monochromatic incoming radiation. The outgoing spectrum is determined by integrating over the spectrum of the incoming radiation using the intensity to determine the correct weight. This method makes it possible to study the emerging radiation as a function of frequency and direction. As a first application we have studied the effects of finite optical depth and gas infall on the Sunyaev-Zel'dovich effect (not possible with the extended Kompaneets equation) and discuss the parameter range in which the Boltzmann equation and its expansions can be used. For high temperature clusters ($k_B T_e \gtrsim 15$ keV) relativistic corrections based on a fifth order expansion of the extended Kompaneets equation seriously underestimate the Sunyaev-Zel'dovich effect at high frequencies. The contribution from plasma infall is less important for reasonable velocities. We give a convenient analytical expression for the dependence of the cross-over frequency on temperature, optical depth, and gas infall speed. Optical depth effects are often more important than relativistic corrections, and should be taken into account for high-precision work, but are smaller than the typical kinematic effect from cluster radial velocities.Comment: LateX, 30 pages and 11 figures. Accepted for publication in the Astrophysical Journa

The effect of geometry on charge confinement in three dimensions

We show that, in contrast to the flat case, the Maxwell theory is not confining in the background of the three dimensional BTZ black-hole (covering space). We also study the effect of the curvature on screening behavior of Maxwell-Chern-Simons model in this space-time.Comment: 8 pages. To be published in Europhysics Letter

THE OPEN BALKAN AS A DEVELOPMENT DETERMINANT OF THE WESTERN BALKAN COUNTRIES

The paper starts from the concept of the Open Balkan as a community of countries in the Western Balkans, aimed at strengthening their economic cooperation and development for faster integration in the European Union. Significant attention is paid to the analysis of the interdependence of (in)stability of the state and the economic development of small countries. The position of the Open Balkan and its members is also analysed on the basis of the selected global composite indices. An important subject of the analysis is also the condition of institutional capacities of the members of the Open Balkan and their institutional cooperation from the perspective of faster progress towards the European integration. Two main hypotheses have been tested in the paper: (H1) CEEs countries are not a homogeneous group of countries; and (H2) The Western Balkans is a relatively homogeneous regional integration. To test the convergence hypothesis between 16 Central and Eastern European countries (CEEs), annual data from World Bank’s database on the value of real gross domestic product per capita (in constant dollars 2017, PPP) in the period 2000-2026 were used (projected values for the period until 2026). We employed the method developed by Phillips & Sul (2007) that allows identification of clusters of convergence on the basis of an algorithm that is data-driven and thereby avoids a priori classification of the data into subgroups. Based on the results obtained, it can be concluded that Serbia is the “locomotive” of the Western Balkans and that all countries in this area should join the regional initiative for cooperation, the Open Balkan

Charm and beauty of the Large Hadron Collider

With the acceleration of lead nuclei in the LHC, heavy-ion physics will enter a new energy domain. One of the main novelties introduced by the 30-fold energy-jump from RHIC to the LHC is the abundant heavy-quark production. After discussing a few examples of physics issues that can be addressed using heavy quarks, we present a selection of results on the expected experimental capability of ALICE, the dedicated heavy-ion experiment at the LHC, in the open-heavy-flavour sector.Comment: 10 pages, 5 figures. Invited talk at Strangeness in Quark Matter (SQM) 2004, Cape Town, South Africa, 15-20 September 2004. Submitted to J. Phys.

Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts

PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind and stabilize αB-crystallin (cryAB) in vitro and to produce a similar therapeutic effect in cryAB(R120G) mutant and aged wild-type mice with cataracts. VP1-001 and ent-VP1-001 have identical physicochemical properties. These experiments are designed to critically evaluate whether stereoselective binding to cryAB is required for activity.MethodsWe compared the binding of VP1-001 and ent-VP1-001 to cryAB using in silico docking, differential scanning fluorimetry (DSF), and microscale thermophoresis (MST). Compounds were delivered by six topical administrations to mouse eyes over 2 weeks, and the effects on cataracts and lens refractive measures in vivo were examined. Additionally, lens epithelial and fiber cell morphologies were assessed via transmission electron microscopy.ResultsDocking studies suggested greater binding of VP1-001 into a deep groove in the cryAB dimer compared with ent-VP1-001. Consistent with this prediction, DSF and MST experiments showed that VP1-001 bound cryAB, whereas ent-VP1-001 did not. Accordingly, topical treatment of lenses with ent-VP1-001 had no effect, whereas VP1-001 produced a statistically significant improvement in lens clarity and favorable changes in lens morphology.ConclusionsThe ability of VP1-001 to bind native cryAB dimers is important for its ability to reverse lens opacity in mouse models of cataracts

The Genome of the Chicken DT40 Bursal Lymphoma Cell Line

The chicken DT40 cell line is a widely used model system in the study of multiple cellular processes due to the efficiency of homologous gene targeting. The cell line was derived from a bursal lymphoma induced by avian leukosis virus infection. In this study we characterized the genome of the cell line using whole genome shotgun sequencing and single nucleotide polymorphism array hybridization. The results indicate that wild type DT40 has a relatively normal karyotype except for whole chromosome copy number gains, and no karyotype variability within stocks. In a comparison to two domestic chicken genomes and the Gallus gallus reference genome we found no unique mutational processes shaping the DT40 genome except for a mild increase in insertion and deletion events, particularly deletions at tandem repeats. We mapped coding sequence mutations that are unique to the DT40 genome; mutations inactivating the PIK3R1 and ATRX genes likely contributed to the oncogenic transformation. In addition to a known avian leukosis virus integration in the MYC gene we detected further integration sites that are likely to de-regulate gene expression. The new findings support the hypothesis that DT40 is a typical transformed cell line with a relatively intact genome, therefore it is well suited to the role of a model system for DNA repair and related processes. The sequence data generated by this study, including a searchable de novo genome assembly and annotated lists of mutated genes, will support future research using this cell line