Cadmium, zinc and iron interactions in the tissues of bank vole Clethrionomys glareolus after exposure to low and high doses of cadmium chloride

In present study, bank voles Clethrionomys glareolus were peritioneally injected with different doses of cadmium, 0, 1.5, 3.0 mg Cd/kg body mass. Animals were sacrificed on the 21st day after cadmium exposure and the liver and kidney were obtained for cadmium, zinc and iron analysis using atomic absorption spectrometry. Results showed that cadmium had accumulated in the tissues according to dosage and sex. Cadmium affected the survival and body masses of dosed females. Cadmium decreased the iron concentrations in the liver of voles, whereas zinc concentrations increased in both the kidney and liver

Intermittent Preventive Treatment for Malaria in Papua New Guinean Infants Exposed to Plasmodium falciparum and P. vivax: A Randomized Controlled Trial

A three-arm randomized trial conducted among infants in Papua New Guinea estimates the preventive effect against malaria episodes of intermittent preventive treatment, in an area where children are exposed to both falciparum and vivax malaria

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

A key determinant of geriatric frailty is sarcopenia, the age-associated loss of skeletal muscle mass and strength. Although the etiology of sarcopenia is unknown, the correlation during aging between the loss of activity of satellite cells, which are endogenous muscle stem cells, and impaired muscle regenerative capacity has led to the hypothesis that the loss of satellite cell activity is also a cause of sarcopenia. We tested this hypothesis in male sedentary mice by experimentally depleting satellite cells in young adult animals to a degree sufficient to impair regeneration throughout the rest of their lives. A detailed analysis of multiple muscles harvested at various time points during aging in different cohorts of these mice showed that the muscles were of normal size, despite low regenerative capacity, but did have increased fibrosis. These results suggest that lifelong reduction of satellite cells neither accelerated nor exacerbated sarcopenia and that satellite cells did not contribute to the maintenance of muscle size or fiber type composition during aging, but that their loss may contribute to age-related muscle fibrosis

Assessment of Shoreline Changes using Historical Satellite Images and Geospatial Analysis along the Lake Salda in Turkey

WOS: 000527535700001This study was performed along the shorelines of Lake Salda in Turkey during the elapsed period from 1975 to 2019 in order to detect shoreline changes. Within this framework, geographic information system, digital shoreline analysis system, Modified Normalized Difference Water Index, and multi-temporal satellite images were utilized. The measurement of shoreline displacement was mainly divided into six analysis regions. In digital shoreline analysis system, several statistical parameters such as end point rate, linear regression rate, shoreline change envelope, and net shoreline movement were computed to measure the rates of shoreline displacement in terms of erosion and accretion. The maximum shoreline change between 1975 and 2019 was determined as 556.45 m by shoreline change envelope parameter. The maximum shoreline change was 16.35 m/year by end point rate parameter and 12.91 m/year by linear regression rate parameter. While erosion has been observed in 3rd, 4th and 6th segments, accretion has been observed in other segments. When all the transects were taken into consideration, an accretion observed. The results indicate that there is a decrease in area of the lake. Experiment results show that integrated use of multi-temporal satellite images and statistical parameters are very effective and useful for shoreline change analysis. It is thought that the structures such as irrigation pond and dam that are built on the streams that recharge the lake and average rainfall and average temperature conditions are the main reasons of the fluctuations and changes in the shorelines