4,071 research outputs found
A Comprehensive Survey of Brane Tilings
An infinite class of gauge theories can be engineered on
the worldvolume of D3-branes probing toric Calabi-Yau 3-folds. This kind of
setup has multiple applications, ranging from the gauge/gravity correspondence
to local model building in string phenomenology. Brane tilings fully encode the
gauge theories on the D3-branes and have substantially simplified their
connection to the probed geometries. The purpose of this paper is to push the
boundaries of computation and to produce as comprehensive a database of brane
tilings as possible. We develop efficient implementations of brane tiling tools
particularly suited for this search. We present the first complete
classification of toric Calabi-Yau 3-folds with toric diagrams up to area 8 and
the corresponding brane tilings. This classification is of interest to both
physicists and mathematicians alike.Comment: 39 pages. Link to Mathematica modules provide
Fungi in the future: interannual variation and effects of atmospheric change on arbuscular mycorrhizal fungal communities
Understanding the natural dynamics of arbuscular mycorrhizal (AM) fungi and their response to global environmental change is essential for the prediction of future plant growth and ecosystem functions. We investigated the long-term temporal dynamics and effect of elevated atmospheric carbon dioxide (CO2) and ozone (O3) concentrations on AM fungal communities.
Molecular methods were used to characterize the AM fungal communities of soybean (Glycine max) grown under elevated and ambient atmospheric concentrations of both CO2 and O3 within a free air concentration enrichment experiment in three growing seasons over 5 yr.
Elevated CO2 altered the community composition of AM fungi, increasing the ratio of Glomeraceae to Gigasporaceae. By contrast, no effect of elevated O3 on AM fungal communities was detected. However, the greatest compositional differences detected were between years, suggesting that, at least in the short term, large-scale interannual temporal dynamics are stronger mediators than atmospheric CO2 concentrations of AM fungal communities.
We conclude that, although atmospheric change may significantly alter AM fungal communities, this effect may be masked by the influences of natural changes and successional patterns through time. We suggest that changes in carbon availability are important determinants of the community dynamics of AM fungi
The performance of Mini Wright peak flow meters after prolonged use
AbstractThe accuracy of 84 new and 35 old Mini Wright peak flow meters were tested using a servo-controlled pump system. The 95% confidence limits for flow measurement across the range of the new meters was between ± 151 minâ1 at the lower end of the range and ± 281 minâ1 at the top of the range. The readings for 22 (63%) of the old meters (age range 1â13 yr) were within these 95% confidence limits. For the remaining 13 old meters (age range 1â13 yr) whose readings were not within these limits, there were 11 meters with readings falling below and two meters with readings above these limits. Twelve of these old meters were washed and retested and there was no significant change in their readings. Twenty of the new meters were retested after 1 yr of continuous use and their readings were significantly higher with a median value of 51 minâ1 across the range, although only two of these 20 meters had readings outside the 95% confidence limits set from the 84 new meters. It is concluded that whilst Mini Wright meters aged up to 14 yr can give readings which are as good as new meters, some meters demonstrate significant changes in readings after only 1 yr and washing did not correct this change. It is recommended that clinicians prescribing peak expiratory flow (PEF) meters should be responsible for checking the patient's meter as well as their PEF readings at clinic visits
Constructing multiple unique input/output sequences using metaheuristic optimisation techniques
Multiple unique input/output sequences (UIOs) are often used to generate robust and compact test sequences in finite state machine (FSM) based testing. However, computing UIOs is NP-hard. Metaheuristic optimisation techniques (MOTs) such as genetic algorithms (GAs) and simulated annealing (SA) are effective in providing good solutions for some NP-hard problems. In the paper, the authors investigate the construction of UIOs by using MOTs. They define a fitness function to guide the search for potential UIOs and use sharing techniques to encourage MOTs to locate UIOs that are calculated as local optima in a search domain. They also compare the performance of GA and SA for UIO construction. Experimental results suggest that, after using a sharing technique, both GA and SA can find a majority of UIOs from the models under test
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Influence of biosurfactants on mass transfer, biodegradation, and transport of mixed wastes in multiphase systems: Final report
The overall results of this project suggest that is situ treatment with biosurfactants has the potential to be an effective,economical, and nontoxic remediation technology. Specifically, we have demonstrated that a rhamnolipid biosurfactant may be used to increase the apparent solubility and biodegradation rate of organic compounds
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Soil aggregate stabilization and carbon sequestration: Feedbacks through organomineral associations
Primary production (specifically, the rate and quality of C transfer below ground) and soil microbial activity (specifically, the rates of C transformation and decay) are recognized as the overall biological processes governing soil organic C (SOC) dynamics. These two processes and, hence, SOC cycling and storage are controlled by complex underlying biotic and abiotic interactions and feedbacks, most of which can be tied in one way or another to the influences of the five state factors related to soil formation, and many of which are sensitive to management practices. Overall, C input rates and quality are largely dependent on climate (especially temperature and precipitation), vegetation type and landscape, soil type, and management practices. Decomposition processes and turnover rates, however, are greatly influenced by climate, the type and quality of organic matter (e.g., N content and the ratios of C:N and lignin:N), chemical or physicochemical associations of organic matter (OM) with soil mineral components, and the location of OM within the soil
Estimating the feasibility of transition paths in extended finite state machines
There has been significant interest in automating testing on the basis of an extended finite state machine (EFSM) model of the required behaviour of the implementation under test (IUT). Many test criteria require that certain parts of the EFSM are executed. For example, we may want to execute every transition of the EFSM. In order to find a test suite (set of input sequences) that achieves this we might first derive a set of paths through the EFSM that satisfy the criterion using, for example, algorithms from graph theory. We then attempt to produce input sequences that trigger these paths. Unfortunately, however, the EFSM might have infeasible paths and the problem of determining whether a path is feasible is generally undecidable. This paper describes an approach in which a fitness function is used to estimate how easy it is to find an input sequence to trigger a given path through an EFSM. Such a fitness function could be used in a search-based approach in which we search for a path with good fitness that achieves a test objective, such as executing a particular transition, and then search for an input sequence that triggers the path. If this second search fails then we search for another path with good fitness and repeat the process. We give a computationally inexpensive approach (fitness function) that estimates the feasibility of a path. In order to evaluate this fitness function we compared the fitness of a path with the ease with which an input sequence can be produced using search to trigger the path and we used random sampling in order to estimate this. The empirical evidence suggests that a reasonably good correlation (0.72 and 0.62) exists between the fitness of a path, produced using the proposed fitness function, and an estimate of the ease with which we can randomly generate an input sequence to trigger the path
B Cells Directly Tolerize CD8+ T Cells
This report investigates the response of CD8+ T cells to antigens presented by B cells. When C57BL/6 mice were injected with syngeneic B cells coated with the Kb-restricted ovalbumin (OVA) determinant OVA257â264, OVA-specific cytotoxic T lymphocyte (CTL) tolerance was observed. To investigate the mechanism of tolerance induction, in vitroâactivated CD8+ T cells from the Kb-restricted, OVA-specific T cell receptor transgenic line OT-I (OT-I cells) were cultured for 15 h with antigen-bearing B cells, and their survival was determined. Antigen recognition led to the killing of the B cells and, surprisingly, to the death of a large proportion of the OT-I CTLs. T cell death involved Fas (CD95), since OT-I cells deficient in CD95 molecules showed preferential survival after recognition of antigen on B cells. To investigate the tolerance mechanism in vivo, naive OT-I T cells were adoptively transferred into normal mice, and these mice were coinjected with antigen-bearing B cells. In this case, OT-I cells proliferated transiently and were then lost from the secondary lymphoid compartment. These data provide the first demonstration that B cells can directly tolerize CD8+ T cells, and suggest that this occurs via CD95-mediated, activation-induced deletion
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