Compatibility of state assignments and pooling of information

© 2015 American Physical Society. We say that two (or more) state assignments for one and the same quantum system are compatible if they could represent the assignments of observers with differing information about the system. A criterion for compatibility was proposed in [Phys. Rev. A 65, 032315 (2002)PLRAAN1050-294710.1103/PhysRevA.65.032315]; however, this leaves unanswered the question of whether there are degrees of compatibility which could be represented by some quantitative measure, and whether there is a straightforward procedure whereby the observers can pool their information to arrive at a unique joint state assignment. We argue that such measures are only sensible given some assumption about what kind of information was used in making the state assignments in the first place, and that in general state assignments do not represent all of the information possessed by the observers. However, we examine one particular measure and show that it has a straightforward interpretation, assuming that the information was acquired from a particular type of measurement, and that in this case there is a natural rule for pooling information. We extend this measure to compatibility of states for k observers and show that the value is the solution to a semidefinite program. Similar compatibility measures can be defined for alternative notions of state compatibility, including post-Peierls and equal support compatibilities

Process and material flow design for vise manufacturing with routing sheet and from to chart

Process design is important steps in production layout planning. At this step, processes and machines for making parts and products are identified. Then these processes and machines are arranged so the flow of materials can be minimized. Vise is a support tool for various manufacturing processes such as cutting, drilling and grinding. Vise consist of various parts such as platform base, body and clamping parts. To make these various parts several manufacturing processes are required. This paper aims to demonstrate the use of routing sheet to identify processes and machines to manufacture vise as well as to show the use of from to chart to arrange those machines in order to minimize material flows. Several machines configurations with minimum material flows are presented

Geometric control of myogenic cell fate.

This work combines expertise in stem cell biology and bioengineering to define the system for geometric control of proliferation and differentiation of myogenic progenitor cells. We have created an artificial niche of myogenic progenitor cells, namely, modified extracellular matrix (ECM) substrates with spatially embedded growth or differentiation factors (GF, DF) that predictably direct muscle cell fate in a geometric pattern. Embedded GF and DF signal progenitor cells from specifically defined areas on the ECM successfully competed against culture media for myogenic cell fate determination at a clearly defined boundary. Differentiation of myoblasts into myotubes is induced in growth-promoting medium, myotube formation is delayed in differentiation-promoting medium, and myogenic cells, at different stages of proliferation and differentiation, can be induced to coexist adjacently in identical culture media. This method can be used to identify molecular interactions between cells in different stages of myogenic differentiation, which are likely to be important determinants of tissue repair. The designed ECM niches can be further developed into a vehicle for transplantation of myogenic progenitor cells maintaining their regenerative potential. Additionally, this work may also serve as a general model to engineer synthetic cellular niches to harness the regenerative potential of organ stem cells

The sensitivity and specificity of the conventional symptoms and signs in making a diagnosis of acute appendicitis

Introduction: Simple appendicitis can progress to perforation, which is associated with a much higher morbidity and mortality. So, surgeons have therefore been inclined to operate when the diagnosis is probable rather than wait until it is certain. Objective: This study is designed to evaluate the sensitivity and specificity of clinical examination in the diagnosis of acute appendicitis.Methods: The study included 866 patients of acute appendicitis who had undergone appendicectomy with preoperative diagnosis of acute appendicitis. They were analyzed retrospectively. The parameters evaluated were age/gender, clinical presentation (signs and symptoms) and total white blood cell counts. The operative findings were recorded and the inflammation of the appendix was graded into normal, acutely inflamed and gangrenous.Results: Clinical diagnosis was made correctly in 807 (93.2%) of the patients. White blood cells count ranged from 3.70 to 45.30 /mm3 (mean 17.5353 /mm3). It wa

A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection

Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor solubility and permeability, thus leading to the development of intracellular pathogens induced multi-drug resistance and biofilms formation. To synergistically improve the biopharmaceutical parameters of CIP, a hyaluronic acid (FDA approved biocompatible polymer) functionalized self-nano emulsifying drug delivery system (HA-CIP-SNEDDS) was designed in the present study. SNEDDS formulations were tested via solubility, droplet size, zeta potential, a polydispersity index, thermodynamic stability, surface morphology, solid-state characterization, drug loading/release, cellular uptake, and biocompatibility. The final (HA-CIP-SNEDDS) formulation exhibited a mean droplet size of 50 nm with the 0.3 poly dispersity index and negative zeta potential (-11.4 mV). HA-based SNEDDS containing CIP showed an improved ability to permeate goat intestinal mucus. After 4 h, CIP-SNEDDS showed a 2-fold and HA-CIP-SNEDDS showed a 4-fold permeation enhancement as compared to the free CIP. Moreover, 80% drug release of HA-CIP-SNEDDS was demonstrated to be superior and sustained for 72 h in comparison to free CIP. However, anti-biofilm activity of HA-CIP-SNEDDS against Salmonella typhi was higher than CIP-SNEDDS and free CIP. HA-CIP-SNEDDS exhibited increased biocompatibility and improved oral pharmacokinetics as compared to free CIP. Taken together, HA-CIP-SNEDDS formulation seems to be a promising agent against Salmonella typhi with a strong targeting potential

Baryon-Baryon Interactions

After a short survey of some topics of interest in the study of baryon-baryon scattering, the recent Nijmegen energy dependent partial wave analysis (PWA) of the nucleon-nucleon data is reviewed. In this PWA the energy range for both pp and np is now 0 < Tlab < 350 MeV and a chi^2_{d.o.f.}=1.08 was reached. The implications for the pion-nucleon coupling constants are discussed. Comments are made with respect to recent discussions around this coupling constant in the literature. In the second part, we briefly sketch the picture of the baryon in several, more or less QCD-based, quark-models that have been rather prominent in the literature. Inspired by these pictures we constructed a new soft-core model for the nucleon-nucleon interaction and present the first results of this model in a chi^2 -fit to the new multi-energy Nijmegen PWA. With this new model we succeeded in narrowing the gap between theory and experiment at low energies. For the energies Tlab = 25-320 MeV we reached a record low chi^2_{p.d.p.} = 1.16. We finish the paper with some conclusions and an outlook describing the extension of the new model to baryon-baryon scattering.Comment: 12 pages LaTeX and one postscript figure included. Invited talk presented at the XIVth European Conference of Few-Body Problems in Physics, Amsterdam, August 23-28, 199

Questioning Classic Patient Classification Techniques in Gait Rehabilitation: Insights from Wearable Haptic Technology

Classifying stroke survivors based on their walking abilities is an important part of the gait rehabilitation process. It can act as powerful indicator of function and prognosis in both the early days after a stroke and long after a survivor receives rehabilitation. This classification often relies solely on walking speed; a quick and easy measure, with only a stopwatch needed. However, walking speed may not be the most accurate way of judging individual’s walking ability. Advances in technology mean we are now in a position where ubiquitous and wearable technologies can be used to elicit much richer measures to characterise gait. In this paper we present a case study from one of our studies, where within a homogenous group of stroke survivors (based on walking speed classification) important differences in individual results and the way they responded to rhythmic haptic cueing were identified during the piloting of a novel gait rehabilitation technique

Millimeter wave propagation measurements and characteristics for 5G system

In future 5G systems, the millimeter wave (mmWave) band will be used to support a large capacity for current mobile broadband. Therefore, the radio access technology (RAT) should be made available for 5G devices to help in distinct situations, for example device-to-device communications (D2D) and multi-hops. This paper presents ultra-wideband channel measurements for millimeter wave bands at 19, 28, and 38 GHz. We used an ultra-wideband channel sounder (1 GHz bandwidth) in an indoor to outdoor (I2O) environment for non-line-of-sight (NLOS) scenarios. In an NLOS environment, there is no direct path (line of sight), and all of the contributed paths are received from different physical objects by refection propagation phenomena. Hence, in this work, a directional horn antenna (high gain) was used at the transmitter, while an omnidirectional antenna was used at the receiver to collect the radio signals from all directions. The path loss and temporal dispersion were examined based on the acquired measurement data—the 5G propagation characteristics. Two different path loss models were used, namely close-in (CI) free space reference distance and alpha-beta-gamma (ABG) models. The time dispersion parameters were provided based on a mean excess delay, a root mean square (RMS) delay spread, and a maximum excess delay. The path loss exponent for this NLOS specific environment was found to be low for all of the proposed frequencies, and the RMS delay spread values were less than 30 ns for all of the measured frequencies, and the average RMS delay spread values were 19.2, 19.3, and 20.3 ns for 19, 28, and 38 GHz frequencies, respectively. Moreover, the mean excess delay values were found also at 26.1, 25.8, and 27.3 ns for 19, 28, and 38 GHz frequencies, respectively. The propagation signal through the NLOS channel at 19, 28, and 38 GHz was strong with a low delay; it is concluded that these bands are reliable for 5G systems in short-range applications

Presumptive self-diagnosis of malaria and other febrile illnesses in Sierra Leone

Introduction: The objective of this study was to evaluate the prevalence of self-diagnosis of malaria and other febrile illnesses in Bo, Sierra Leone. Methods: All households in two neighboring sections of Bo were invited to participate in a cross-sectional survey. Results: A total of 882 households (an 85% participation rate) that were home to 5410 individuals participated in the study. Of the 910 individuals reported to have had what the household considered to be malaria in the past month, only 41% were diagnosed by a healthcare professional or a laboratory test. Of the 1402 individuals reported to have had any type of febrile illness within the past six months, only 34% had sought a clinical or laboratory diagnosis. Self-diagnosis of influenza, yellow fever, typhoid, and pneumonia was also common. Conclusion: Self-diagnosis and presumptive treatment with antimalarial drugs and other antibiotic medications that are readily available without a prescription may compromise health outcomes for febrile adults and children.Key words: Malaria, fevers, self-care, health services accessibility, community pharmacy services, West Afric

Conservation genomics reveals possible illegal trade routes and admixture across pangolin lineages in Southeast Asia

The use of genome-wide genetic markers is an emerging approach for informing evidence-based management decisions for highly threatened species. Pangolins are the most heavily trafficked mammals across illegal wildlife trade globally, but critically endangered Sunda pangolins (Manis javanica) have not been widely studied in insular Southeast Asia. We used > 12,000 single nucleotide polymorphic markers (SNPs) to assign pangolin seizures from illegal trade of unknown origin to possible geographic sources via genetic clustering with pangolins of known origin. Our SNPs reveal three previously unrecognized genetic lineages of Sunda pangolins, possibly from Borneo, Java and Singapore/Sumatra. The seizure assignments suggest the majority of pangolins were traded from Borneo to Java. Using mitochondrial markers did not provide the same resolution of pangolin lineages, and to explore if admixture might explain these differences, we applied sophisticated tests of introgression using > 2000 SNPs to investigate secondary gene flow between each of the three Sunda pangolin lineages. It is possible the admixture which we discovered is due to human-mediated movements of pangolins. Our findings impact a range of conservation actions, including tracing patterns of trade, repatriation of rescue animals, and conservation breeding. In order to conserve genetic diversity, we suggest that, pending further research, each pangolin lineage should as a precaution be protected and managed as an evolutionarily distinct conservation unit