An experimental comparison of several PWM controllers for a single-phase AC-DC converter

Published versio

The impact of psychosis genome-wide associated ZNF804A variation on verbal fluency connectivity

WOS:000425076000003Schizophrenia (SCZ) and bipolar disorder (BD) have high heritability. Genome-wide association studies (GWAS) have identified ZNF804A as a significant risk gene for both illnesses. A validation of this finding at the brain systems-level is imperative as there is still little understanding of how it heightens risk. Based in part on our recent findings of an effect on widespread decreased white matter microstructural fractional anisotropy (putatively a proxy of its integrity), particularly strong in SCZ, we asked whether the risk allele has a detrimental effect on regional brain activation and functional connectivity during a type of cognitive processing which is, together with its neural correlates, impaired in BD and SCZ: verbal fluency. Functional MRI and genotype data was collected from 80 healthy volunteers, and 54 SCZ and 40 BD patients. A standard multifactorial analysis of variance using statistical parametric mapping and significance correction of FWE p < 0.05 was used. We found the GWAS risk allele A was associated with decreased positive functional coupling between the left precentral gyrus/inferior frontal gyrus (i.e. the most highly recruited area for the task) and: 1) the left inferior frontal gyrus, and 2) the left posterior cingulate gyrus, encompassing the precuneus; both as a main effect across controls and psychosis patients. Such association of the risk allele with reduced functional connectivity (with no area where the opposite main effect was detected), converges with findings in other tasks, our previous finding of its widespread impact on brain white matter microstructure, and with the dysconnectivity hypothesis of SCZ.info:eu-repo/semantics/publishedVersio

More than a feeling: A unified view of stress measurement for population science.

Stress can influence health throughout the lifespan, yet there is little agreement about what types and aspects of stress matter most for human health and disease. This is in part because "stress" is not a monolithic concept but rather, an emergent process that involves interactions between individual and environmental factors, historical and current events, allostatic states, and psychological and physiological reactivity. Many of these processes alone have been labeled as "stress." Stress science would be further advanced if researchers adopted a common conceptual model that incorporates epidemiological, affective, and psychophysiological perspectives, with more precise language for describing stress measures. We articulate an integrative working model, highlighting how stressor exposures across the life course influence habitual responding and stress reactivity, and how health behaviors interact with stress. We offer a Stress Typology articulating timescales for stress measurement - acute, event-based, daily, and chronic - and more precise language for dimensions of stress measurement

Influencia de doses e volumes de aplicação na eficácia do glifosato no controle de plantas daninhas em seringal em formação.

Os objetivos deste trabalho foram avaliar a viabilidade da aplicação de glifosato em pos-emergencia no controle de ervas em seringueira em formação e determinar o efeito de doses de herbicidas e volume de calda aplicados com aparelho rotativo que produz goticulas de diametro controlado (CDA), em ultra baixo e baixo volume, comparado com aparelho tradicional, em medio volume de calda.bitstream/item/67392/1/CPAF-RO-DOCUMENTOS-30-INFLUENCIA-DE-DOSES-E-VOLUMES-DE-APLICACAO-NA-EFICACIA-DO-GLIFOSATO-NO-CONT.pd

A busca pela excelência laboratorial: acreditação de ensaios do Laboratório de Análise de Sementes da Embrapa Milho e Sorgo baseada na Norma ISO/IEC 17025: 2005.

A acreditação na ISO/IEC 17025:2005, com o conseqüente reconhecimento da competência técnica para realizar ensaios e aceitação dos resultados obtidos, é um instrumento eficaz para a remoção de barreiras técnicas ao comércio nacional e internacional. A qualidade comparável de resultados forma a base da aceitação mútua entre os países que adotam essa norma, além de se evitar a duplicação de testes, reduzindo o desperdício de tempo e recursos. A metodologia para implantação do sistema de gestão da qualidade (SG) no LAS da Embrapa Milho e Sorgo foi baseada na aplicação de ações de gestão, levantamento das necessidades, sensibilização e capacitação da equipe, documentação e validação do sistema de gestão da qualidade. Desde o ano de 2003, o LAS iniciou a implantação do SG com resultados parciais e lentos. A parceria entre duas Unidades da Embrapa (Embrapa Meio Ambiente, Unidade da Embrapa certificada desde 2005 na ISO 9001 :2000, e Milho e Sorgo) mostrou-se bastante eficaz, o que tomou possível a participação da Embrapa Milho e Sorgo num projeto corporativo para melhoria da gestão organizacional, onde essas experiências foram difundidas e compartilhadas. O parecer final sobre o processo de auditoria foi que o LAS da Embrapa Milho e Sorgo demonstrou ter instalações, equipamentos, pessoal e competência para realizar as análises do escopo do credenciamento e comprovou a implantação de um sistema de gestão da qualidade baseado na Norma NBR ISO /IEC 17025. A equipe auditora do LASO /LANAGRO /MG recomendou que seja concedido o credenciamento no RENASEM solicitado pelo laboratório

Soft singularity and the fundamental length

It is shown that some regular solutions in 5D Kaluza-Klein gravity may have interesting properties if one from the parameters is in the Planck region. In this case the Kretschman metric invariant runs up to a maximal reachable value in nature, i.e. practically the metric becomes singular. This observation allows us to suppose that in this situation the problems with such soft singularity will be much easier resolved in the future quantum gravity then by the situation with the ordinary hard singularity (Reissner-Nordstr\"om singularity, for example). It is supposed that the analogous consideration can be applied for the avoiding the hard singularities connected with the gauge charges.Comment: 5 page

Analysis of plantar pressure and balance of transfemoral amputees compared with non amputee subjects, using their shoes

Plantar pressure and balance of transfemoral amputees was compared with non amputeesubjects. 9 amputees and 18 controls walked over 8m walkway w/a pressure and a force plate.Significant differences registered: COF distance, deltax, deltay, Max/Min APforce, MinMLforceand time, stance and impulse