12,187 research outputs found
Moving through the city with strangers? Public transport as a significant kind of urban public space
Postprin
Car Dependence, Sustainability and the Transport Policy Stalemate : The Potential Trade-offs between Intra- and Inter-generational Equity
Peer reviewedPostprin
From A. rhizogenes RolD to Plant P5CS: Exploiting Proline to Control Plant Development
The capability of the soil bacterium Agrobacterium rhizogenes to reprogram plant development and induce adventitious hairy roots relies on the expression of a few root-inducing genes (rol A, B, C and D), which can be transferred from large virulence plasmids into the genome of susceptible plant cells. Contrary to rolA, B and C, which are present in all the virulent strains of A. rhizogenes and control hairy root formation by affecting auxin and cytokinin signalling, rolD appeared non-essential and not associated with plant hormones. Its role remained elusive until it was discovered that it codes for a proline synthesis enzyme. The finding that, in addition to its role in protein synthesis and stress adaptation, proline is also involved in hairy roots induction, disclosed a novel role for this amino acid in plant development. Indeed, from this initial finding, proline was shown to be critically involved in a number of developmental processes, such as floral transition, embryo development, pollen fertility and root elongation. In this review, we present a historical survey on the rol genes focusing on the role of rolD and proline in plant development
Milanâs pollution charge : sustainable transport and the politics of evidence
Non peer reviewedPostprin
Relationship between socioeconomic status and asymptomatic peripheral arterial disease: a retrospective study
Alkenone producers during late Oligocene-early Miocene revisited
This study investigates ancient alkenone producers among the late Oligoceneâearly Miocene coccolithophores recorded at Deep Sea Drilling Project (DSDP) Site 516. Contrary to common assumptions, Reticulofenestra was not the most important alkenone producer throughout the studied time interval. The comparison between coccolith species-specific absolute abundances and alkenone contents in the same sedimentary samples shows that Cyclicargolithus abundances explain 40% of the total variance of alkenone concentration and that the species Cyclicargolithus floridanus was a major alkenone producer, although other related taxa may have also contributed to the alkenone production at DSDP Site 516. The distribution of the different alkenone isomers (MeC37:2, EtC38:2, and MeC38:2) remained unchanged across distinct changes in species composition, suggesting similar diunsaturated alkenone compositions within the Noelaerhabdaceae family during the late Oligoceneâearly Miocene. However, the overall larger cell size of Cyclicargolithus may have implications for the alkenone-based reconstruction of past partial pressure of CO2. Our results underscore the importance of a careful evaluation of the most likely alkenone producers for periods (>1.85 Ma) predating the first occurrence of contemporary alkenone producers (i.e., Emiliania huxleyi and Gephyrocapsa oceanica)
An approach to the association between gastrointestinal hormones and dry matter intake in ruminants
Las hormonas gastrointestinales estĂĄn relacionadas con el consumo de alimento. A pesar de que el mecanismo de acciĂłn de muchas de estas hormonas en animales no rumiantes es relativamente entendido, en rumiantes su funciĂłn es aĂșn poco comprendida y muchas veces contradictoria. Por ello, en este ensayo se discute la relaciĂłn de la insulina, ghrelina, colecistoquinina (CCK), pĂ©ptido tirosina tirosina (PYY) y los pĂ©ptidos que derivan del gen del proglucagon (oxintomodulina, glicentina y pĂ©ptidos similares al glucagĂłn 1 y 2 (GLP-1 y GLP-2)) con el consumo de alimento en rumiantes. Estas hormonas tambiĂ©n tienen una funciĂłn en la regulaciĂłn del metabolismo energĂ©tico, lo cual se discutirĂĄ en otro ensayo. Las evidencias sugieren que en rumiantes, insulina, CCK y el GLP-1 disminuyen el consumo, mientras que ghrelina lo aumenta. La funciĂłn de oxintomodulina, GLP-2 y PYY se conoce poco en rumiantes.Gastrointestinal hormones are related to feed intake. Despite the fact that the mechanisms of action of many of these hormones in nonâruminant animals is relatively well known, in ruminants their function is still not understood, and results reported in the literature are often contradictory. For this reason, this essay discusses how insulin, ghrelin, colecistokinin (CCK), peptide tyrosine tyrosine (PYY) and peptides derived from the proglucagon gen (oxyntomodlin, glicentin and glucagonâlike peptides 1 and 2 (GLPâ1 and GLPâ2)) are related to dry matter intake (DMI) in ruminants. These hormones also have a function in the regulation of metabolism, which will be discussed in another essay. The evidence suggests that in ruminants, insulin, CCK and GLPâ1 reduce DMI, while ghrelin increases DMI. The function of oxyntomodulin, GLPâ2 and PYY is little known in ruminants.Fil: Relling, Alejandro Enrique. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico CONICET- La Plata. Instituto de GenĂ©tica Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de GenĂ©tica Veterinaria; ArgentinaFil: Pinos RodrĂguez, J. Manuel. Universidad AutĂłnoma de San Luis PotosĂ. Instituto de InvestigaciĂłn de Zonas DesĂ©rticas; MĂ©xicoFil: Mattioli, Guillermo Alberto. Facultad de Ciencias Veterinarias. Universidad Nacional de La Plata; Argentin
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