Comment on ``Stripes and the t-J Model''

This is a comment being submitted to Physical Review Letters on a recent letter by Hellberg and Manousakis on stripes in the t-J model.Comment: One reference correcte

The first analytical expression to estimate photometric redshifts suggested by a machine

We report the first analytical expression purely constructed by a machine to determine photometric redshifts ($z_{\rm phot}$) of galaxies. A simple and reliable functional form is derived using $41,214$ galaxies from the Sloan Digital Sky Survey Data Release 10 (SDSS-DR10) spectroscopic sample. The method automatically dropped the $u$ and $z$ bands, relying only on $g$, $r$ and $i$ for the final solution. Applying this expression to other $1,417,181$ SDSS-DR10 galaxies, with measured spectroscopic redshifts ($z_{\rm spec}$), we achieved a mean $\langle (z_{\rm phot} - z_{\rm spec})/(1+z_{\rm spec})\rangle\lesssim 0.0086$ and a scatter $\sigma_{(z_{\rm phot} - z_{\rm spec})/(1+z_{\rm spec})}\lesssim 0.045$ when averaged up to $z \lesssim 1.0$. The method was also applied to the PHAT0 dataset, confirming the competitiveness of our results when faced with other methods from the literature. This is the first use of symbolic regression in cosmology, representing a leap forward in astronomy-data-mining connection.Comment: 6 pages, 4 figures. Accepted for publication in MNRAS Letter

Categorical Groups, Knots and Knotted Surfaces

We define a knot invariant and a 2-knot invariant from any finite categorical group. We calculate an explicit example for the Spun Trefoil.Comment: 40 pages, lots of figures. Second version: Added example and discussion, clarification of the fact that the maps associated with Reidemeister Moves are well define

DEveloping a Complex Intervention for DEteriorating Patients using Theoretical Modelling (DECIDE study): study protocol

AIM: To develop a theory-based complex intervention (targeting nursing staff), to enhance enablers and overcome barriers to enacting expected behaviour when monitoring patients and responding to abnormal vital signs that signal deterioration. DESIGN: A mixed method design including structured observations on hospital wards, field notes, brief, un-recorded interviews and semi-structured interviews to inform the development of an intervention to enhance practice. METHODS: Semi-structured interviews will be conducted with nursing staff using a topic guide informed by the Theoretical Domains Framework. Semi-structured interviews will be transcribed verbatim and coded deductively into the 14 Theoretical Domains Framework domains and then inductively into 'belief statements'. Priority domains will be identified and mapped to appropriate behaviour change techniques. Intervention content and mode of delivery (how behaviour change techniques are operationalised) will be developed using nominal groups, during which participants (clinicians) will rank behaviour change techniques /mode of delivery combinations according to acceptability and feasibility. Findings will be synthesised to develop an intervention manual. DISCUSSION: Despite being a priority for clinicians, researchers and policymakers for two decades, 'sub-optimal care' of the deteriorating ward patient persists. Existing interventions have been largely educational (i.e., targeting assumed knowledge deficits) with limited evidence that they change staff behaviour. Staff behaviour when monitoring and responding to abnormal vital signs is likely influenced by a range of mediators that includes barriers and enablers. IMPACT: Systematically applying theory and evidence-based methods, will result in the specification of an intervention which is more likely to result in behaviour change and can be tested empirically in future research. This article is protected by copyright. All rights reserved

Structural studies of mesoporous ZrO2_{2}-CeO2_{2} and ZrO2_{2}-CeO2_{2}/SiO2_{2} mixed oxides for catalytical applications

In this work the synthesis of ZrO$_{2}$-CeO$_{2}$ and ZrO$_{2}$-CeO$_{2}$/SiO$_{2}$ were developed, based on the process to form ordered mesoporous materials such as SBA-15 silica. The triblock copolymer Pluronic P-123 was used as template, aiming to obtain crystalline single phase walls and larger specific surface area, for future applications in catalysis. SAXS and XRD results showed a relationship between ordered pores and the material crystallization. 90% of CeO$_{2}$ leaded to single phase homogeneous ceria-zirconia solid solution of cubic fluorite structure (Fm$\bar{3}$m). The SiO$_{2}$ addition improved structural and textural properties as well as the reduction behavior at lower temperatures, investigated by XANES measurements under H$_{2}$ atmosphere

A polarised infrared flare from Sagittarius A* and the signatures of orbiting plasma hotspots

In this article we summarise and discuss the infrared, radio, and X-ray emission from the supermassive black hole in the Galactic Centre, SgrA*. We include new results from near-infrared polarimetric imaging observations obtained on May 31st, 2006. In that night, a strong flare in Ks band (2.08 microns) reaching top fluxes of ~16 mJy could be observed. This flare was highly polarised (up to ~40%) and showed clear sub-structure on a time scale of 15 minutes, including a swing in the polarisation angle of about 70 degrees. For the first time we were able to observe both polarised flux and short-time variability, with high significance in the same flare event. This result adds decisive information to the puzzle of the SgrA* activity. The observed polarisation angle during the flare peak is the same as observed in two events in 2004 and 2005. Our observations strongly support the dynamical emission model of a decaying plasma hotspot orbiting SgrA* on a relativistic orbit. The observed polarisation parameters and their variability with time might allow to constrain the orientation of accretion disc and spin axis with respect to the Galaxy.Comment: 9 pages, 8 figures, accepted for publication in MNRA

Multiscale model for the effects of adaptive immunity suppression on the viral therapy of cancer

Oncolytic virotherapy - the use of viruses that specifically kill tumor cells - is an innovative and highly promising route for treating cancer. However, its therapeutic outcomes are mainly impaired by the host immune response to the viral infection. In the present work, we propose a multiscale mathematical model to study how the immune response interferes with the viral oncolytic activity. The model assumes that cytotoxic T cells can induce apoptosis in infected cancer cells and that free viruses can be inactivated by neutralizing antibodies or cleared at a constant rate by the innate immune response. Our simulations suggest that reprogramming the immune microenvironment in tumors could substantially enhance the oncolytic virotherapy in immune-competent hosts. Viable routes to such reprogramming are either in situ virus-mediated impairing of CD$8^+$ T cells motility or blockade of B and T lymphocytes recruitment. Our theoretical results can shed light on the design of viral vectors or new protocols with neat potential impacts on the clinical practice.Comment: 14 pages, 4 figure

Social Effects in Science: Modelling Agents for a Better Scientific Practice

Science is a fundamental human activity and we trust its results because it has several error-correcting mechanisms. Its is subject to experimental tests that are replicated by independent parts. Given the huge amount of information available, scientists have to rely on the reports of others. This makes it possible for social effects to influence the scientific community. Here, an Opinion Dynamics agent model is proposed to describe this situation. The influence of Nature through experiments is described as an external field that acts on the experimental agents. We will see that the retirement of old scientists can be fundamental in the acceptance of a new theory. We will also investigate the interplay between social influence and observations. This will allow us to gain insight in the problem of when social effects can have negligible effects in the conclusions of a scientific community and when we should worry about them.Comment: 14 pages, 5 figure