28 research outputs found
Probing reflection from aerosols with the near-infrared dayside spectrum of WASP-80b
The presence of aerosols is intimately linked to the global energy budget and
the composition of a planet's atmospheres. Their ability to reflect incoming
light prevents energy from being deposited into the atmosphere, and they shape
spectra of exoplanets. We observed five near-infrared secondary eclipses of
WASP-80b with the Wide Field Camera 3 (WFC3) aboard the \textit{Hubble Space
Telescope} to provide constraints on the presence and properties of atmospheric
aerosols. We detect a broadband eclipse depth of \,ppm for WASP-80b.
We detect a higher planetary flux than expected from thermal emission alone at
, which hints toward the presence of reflecting aerosols on this
planet's dayside, indicating a geometric albedo of at 3. We
paired the WFC3 data with Spitzer data and explored multiple atmospheric models
with and without aerosols to interpret this spectrum. Albeit consistent with a
clear dayside atmosphere, we found a slight preference for near-solar
metallicities and for dayside clouds over hazes. We exclude soot haze formation
rates higher than g cms and tholin formation rates
higher than g cms at . We applied the same
atmospheric models to a previously published WFC3/Spitzer transmission spectrum
for this planet and found weak haze formation. A single soot haze formation
rate best fits both the dayside and the transmission spectra simultaneously.
However, we emphasize that no models provide satisfactory fits in terms of the
chi-square of both spectra simultaneously, indicating longitudinal
dissimilarity in the atmosphere's aerosol composition.Comment: Published in ApJ Letters (20 Oct 2023
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.
Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]
Bob Marley, Bob Dylan
"La guerra continuará existiendo mientras el color de la piel sea másimportante que el de los ojos" (Bob Marley, artista jamaicano) "Ustedes, que fabrican las grandes armas Ustedes, que construyen los aviones de la muerte Ustedes, que construyen todas las bombas Ustedes, que se esconden tras los muros Ustedes, que se esconden detrás de escritorios Sólo quiero que sepan Que puedo verlos a través de sus máscaras".Bob Dylan (Letra Canción “Masters of War”, 1963