Fractional state space analysis of economic systems

This paper examines modern economic growth according to the multidimensional scaling (MDS) method and state space portrait (SSP) analysis. Electing GDP per capita as the main indicator for economic growth and prosperity, the long-run perspective from 1870 to 2010 identifies the main similarities among 34 world partners’ modern economic growth and exemplifies the historical waving mechanics of the largest world economy, the USA. MDS reveals two main clusters among the European countries and their old offshore territories, and SSP identifies the Great Depression as a mild challenge to the American global performance, when compared to the Second World War and the 2008 crisis

Effect of fractional orders in the velocity control of a servo system

AbstractThe application of fractional-order PID controllers is now an active field of research. This article investigates the effect of fractional (derivative and integral) orders upon system’s performance in the velocity control of a servo system. The servo system consists of a digital servomechanism and an open-architecture software environment for real-time control experiments using MATLAB/Simulink tools. Experimental responses are presented and analyzed, showing the effectiveness of fractional controllers. Comparison with classical PID controllers is also investigated

Oral administration of curcumin (curcuma Longa) can attenuate the neutrophil inflammatory response in zymosan-induced arthritis in rats

PURPOSE: To evaluate the effect of curcumin in the acute phase of zymosan-induced arthritis.METHODS: Twenty-eight male rats were subjected to intra-articular infiltration of zymosan of both knees and, in four the infiltration was made with saline. The animals were divided into five groups second received every six hours by gavage: corn oil by (positive and negative control); curcumin (100 mg/kg); prednisone 1 mg/kg/day; prednisone 8 mg/kg. All animals were sacrificed after six, 12, 24 and 48 hours of the infiltration. The knees were removed for evaluation of neutrophil infiltration. The number of neutrophils was counted by computer-assisted analysis of the images. The neutrophil infiltrate was stratified into four grades: 0 = normal; + = mild; ++/+++ = moderate; > ++++ = severe. The results were compared using the Mann-Whitney test and the variance by Kruskal-Wallis test adopting a significance level of 5% (p<0.05).RESULTS: Curcumin reduces inflammatory activity in the first six hours after zymosan-induced arthritis when compared to saline (p<0.01). This was also observed in animals subjected to administration of prednisone (1 mg/kg) and those treated with prednisone (8 mg/kg). Curcumin was more effective than lower doses of prednisone in the first six hours after induction of the arthritis. After 12, 24 and 48 hours, curcumin does not have the same anti-inflammatory effects when compared to prednisone. After 48 hours, prednisone is more effective than curcumin in reducing the inflammatory infiltrate regardless of the dose of prednisone used.CONCLUSION: Oral administration of curcumin reduces inflammation in the first six hours after experimentally zymosan-induced arthritis.To evaluate the effect of curcumin in the acute phase of zymosan-induced arthritis.METHODS: Twenty-eight male rats were subjected to intra-articular infiltration of zymosan of both knees and, in four the infiltration was made with saline. The animals were2911727734sem informaçãosem informaçãoLawrence, R.C., Felson, D.T., Helmick, C.G., Arnold, L.M., Choi, H., Deyo, R.A., Gabriel, S., Wolfe, F., National Arthritis Data Workgroup. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II (2008) Arthritis Rheum, 58 (1), pp. 26-35. , JanMahajan, A., Verma, S., Tandon, V., Osteoarthritis (2005) J Ass Physicians India, 53, pp. 634-641. , Jul, PMID: 16190135Arden, N., Nevitt, M.C., Osteoarthritis: Epidemiology (2006) Best Pract Res Clin Rheumatol, 20 (1), pp. 3-25. , Feb, PMID:16483904Dibonaventura, M., Gupta, S., McDonald, M., Sadosky, A., Evaluating the health and economic impact of osteoarthritis pain in the workforce: results from the National Health and Wellness Survey (2011) BMC Musculoskelet Disord, 12, p. 83. , Apr 28Rocha, F.A., Andrade, L.E., Jancar, S., Immune complex induced arthritis in rats: Role of lipid mediators on cell infiltration (1996) Med Inflam, 5 (2), pp. 104-109. , PMID: 18475706Henrotin, Y.E., Bruckner, P., Pujol, J.P., The role of reactive oxygen species in homeostasis and degradation of cartilage (2003) Osteoarthritis Cartilage, 11 (10), pp. 747-755. , Oct, PMID:13129694Fermor, B., Christensen, S.E., Youn, I., Cernanec, J.M., Davies, C.M., Weinberg, J.B., Oxygen, nitric oxide and articular cartilage (2007) Eur Cell Mater., 13, pp. 56-65. , Apr 11, discussion 65, PMID: 17427142Jurenka, J.S., Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: A review of pre-clinical and clinical research (2009) Altern Med Rev, 14 (2), pp. 141-153. , Jun, PMID:19594223Chopra, A., Lavin, P., Patwardhan, B., Chitre, D., A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees (2004) Clin Rheumatol, 10 (5), pp. 236-245. , Oct, PMID: 17043520Park, C., Moon, D.O., Choi, I.W., Choi, B.T., Nam, T.J., Rhu, C.H., Kwon, T.K., Choi, Y.H., Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis (2007) Int J Mol Med, 20 (3), pp. 365-372. , Sep, PMID: 17671742Funk, J.L., Oyarzo, J.N., Frye, J.B., Chen, G., Lantz, R.C., Jolad, S.D., Sólyom, A.M., Timmermann, B.N., Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis (2006) J Nat Prod, 69 (3), pp. 351-355. , Mar, PMID: 16562833Chaves, H.V., Ribeiro R De, A., De Souza, A.M., Rodrigues E Silva, A.A., Gomes, A.S., Vale, M.L., Bezerra, M.M., Brito, G.A., Experimental model of zymosan-induced arthritis in the rat temporomandibular joint: Role of nitric oxide and neutrophils (2011) J Biomed Biotechnol, 2011, p. 707985Keystone, E.C., Schorlemmer, H.U., Pope, C., Allison, A.C., Zymosan-induced arthritis: A model of chronic proliferative arthritis following activation of the alternative pathway of complement (1977) Arthritis Rheum, 20 (7), pp. 1397-1401. , Sep-Oct, PMID: 911357Gegout, P., Gillet, P., Terlain, B., Netter, P., Zymosan induced arthritis in rats II. Effects of antiinflammatory drugs (1995) Life Sci, 56 (20), pp. PL389-PL394. , PMID: 7723595Berner, J., Gabay, C., Best practice use of corticosteroids in rheumatoid arthritis (2014) Rev Med Suisse, 10 (421), pp. 603-608. , Mar 12, PMID: 24701713Narendhirakannan, R.T., Limmy, T.P., Anti-inflammatory and anti-oxidant properties of Sida rhombifolia stems and roots in adjuvant induced arthritic rats (2012) Immunopharmacol Immunotoxicol, 34 (2), pp. 326-336. , AprAggarwal, B.B., Sundaram, C., Malani, N., Ichikaw, H., Curcumin: The Indian solid gold (2007) Adv Exp Med Biol, 595, pp. 1-75. , PMID: 17569205Anand, P., Kunnumakkara, A.B., Newman, R.A., Aggarwal, B.B., Bioavailability of curcumin: Problems and promises (2007) Mol Pharm, 4 (6), pp. 807-818. , Nov-Dec, PMID: 17999464Taty Anna, K., Elvy Suhana, M.R., Faizah, O., Hamzaini, A.H., Anti-inflammatory effect of Curcuma longa (turmeric) on collagen-induced arthritis: An anatomico-radiological study (2011) Clin Ter, 162 (3), pp. 201-207. , PMID: 21717043Shishodia, S., Sethi, G., Aggarwal, B.B., Curcumin: Getting back to the roots (2005) Ann N Y Acad Sci, 1056, pp. 206-217. , Nov, PMID: 16387689Samuhasaneeto, S., Thong-Ngam, D., Kulaputana, O., Suyasunanont, D., Klaikeaw, N., Curcumin decreased oxidative stress, inhibited NF- kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats (2009) J Biomed Biotechnol, 2009, p. 981963Ramadan, G., Al-Kahtani, M.A., El-Sayed, W.M., Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis (2011) Inflammation, 34 (4), pp. 291-301. , AugPark, C., Moon, D.O., Choi, I.W., Choi, B.T., Nam, T.J., Rhu, C.H., Kwon, T.K., Choi, Y.H., Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis (2007) Int J Mol Med, 20 (3), pp. 365-372. , Sep, PMID: 17671742Mun, S.H., Kim, H.S., Kim, J.W., Ko, N.Y., Kim, D.O.K., Lee, B.Y., Kim, B., Choi, W.S., Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen- induced arthritis: Inhibition of the PKCdelta/JNK/c-Jun pathway (2009) J Pharmacol Sci, 111 (1), pp. 13-21. , Sep, PMID: 19763044Moon, D.O., Kim, M.O., Choi, Y.H., Park, Y.M., Kim, G.Y., Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model (2010) Int Immunopharmacol, 10 (5), pp. 605-610. , MayLantz, R.C., Chen, G.J., Solyom, A.M., Jolad, S.D., Timmermann, B.N., The effect of turmeric extracts on inflammatory mediator production (2005) Phytomedicine, 12 (6-7), pp. 445-452. , Jun, PMID: 16008121Srimal, R.C., Dhawan, B.N., Pharmacology of diferuloyl methane (curcumin), a non-steroidal antiinflammatory agent (1973) J Pharm Pharmacol, 25 (6), pp. 447-452. , Jun, PMID: 4146582Baker, C.L., Jr., Ferguson CM. Future treatment of osteoarthritis (2005) Orthopedics, 28 (2), pp. s227-s234. , Feb, PMID: 15747611Banerjee, M., Tripathi, L.M., Srivastava, V.M., Puri, A., Shukla, R., Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat (2003) Immunopharmacol Immunotoxicol, 25 (2), pp. 213-224. , May, PMID: 12784914Banji, D., Pinnapureddy, J., Banji, O.J., Saidulu, A., Hayath, M.S., Synergistic activity of curcumin with methotrexate in ameliorating Freund’s Complete Adjuvant induced arthritis with reduced hepatotoxicity in experimental animals (2011) Eur J Pharmacol, 668 (1-2), pp. 293-298. , Oct 1Funk, J.L., Frye, J.B., Oyarzo, J.N., Kuscuoglu, N., Wilson, J., McCaffrey, G., Stafford, G., Timmermann, B.N., Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis (2006) Arthritis Rheum, 54 (11), pp. 3452-3464. , Nov, PMID: 17075840Jancinová, V., Perecko, T., Nosál, R., Kostálová, D., Bauerová, K., Drábiková, K., Decreased activity of neutrophils in the presence of diferuloylmethane (curcumin) involves protein kinase C inhibition (2009) Eur J Pharmacol, 612 (1-3), pp. 161-166. , Jun 10Joe, B., Rao, U.J., Lokesh, B.R., Presence of an acidic glycoprotein in the serum of arthritic rats: Modulation by capsaicin and curcumin (1997) Mol Cell Biochem, 169 (1-2), pp. 125-134. , Apr, PMID: 908963

Experiencia en el tratamiento quirúrgico del angiofibroma nasal juvenil en Hospital de Especialidades No 2 Lic. Luis Donaldo Colosio Murrieta. Instituto Mexicano del Seguro Social de Ciudad Obregón, Sonora

Objective: To present our experience and assess the recurrence of juvenile nasopharyngeal angiofibroma after a surgical treatment (open versus endoscopic approach) in the country’s northwestern Department of Otorhinolaryngology. Materials and methods: An observational, retrospective, analytical study. The medical records of patients diagnosed with juvenile nasopharyngeal angiofibroma, who were treated at the Department of Otorhinolaryngology – Head and Neck Surgery of this institution from 2014 to 2017, were reviewed. Results: A total of 19 patients diagnosed with juvenile nasopharyngeal angiofibroma underwent a surgical procedure, out of which 14 had an open surgery and 5 an endoscopic one. Recurrence accounted for 50 % and 40 %, respectively, which was not statistically significant (p = 0.88). However, other variables were compared, such as the need for admission to the Intensive Care Unit (ICU), which was represented by 71 % in the case of the open approach and 20 % for the endoscopic approach, where a significant difference was found (p = 0.04). Conclusions: The study shows no statistically significant advantage of the endoscopic approach versus the open approach, but demonstrates less need for ICU admissions, which would reduce healthcare costs

Sterol and fatty acid profile in negrinha and santulhana varietal olive oils from Trás-os-Montes region

info:eu-repo/semantics/publishedVersio

Behaviour of hybrid corn seeds during storage under different conditions of air temperature and relative humidity

To evaluate the performance of early and normal hybrid corn seeds during storage under different conditions of temperature and relative humidity, Pioneer 3072 and 3210 hybrid seeds were stored under three different conditions, for sixth months. Evaluations of the physiological quality of the seeds were carried out in three bimonthly periods, part of the seeds having been submitted to additional stress at the time tests were conducted. The performance differences between the studied treatments were achieved through the employment of tests of germination, first count, accelerated aging, cold (with and without soil), electrical conductivity and seedling field emergence. It is concluded that: the control of temperature and relative humidity of the storage ambient, mainly relative humidity (dry chamber), favour the conservation of the hybrid corn seed quality.Com o objetivo de avaliar o comportamento de sementes de milho híbrido durante o armazenamento sob condições diversas de temperatura e umidade relativa do ar foram utilizadas sementes do híbrido Pioneer 3072 e 3210, as quais foram armazenadas sob três condições distintas: câmara seca, câmara fria e condição ambiente, durante 6 meses, e avaliadas quanto à qualidade fisiológica em 3 épocas bimestrais distintas, sendo parte submetida à estresse adicional no momento de realização dos testes. Para detecção da diferença de comportamento dos materiais estudados foram empregados os testes de germinação, primeira contagem de germinação, envelhecimento acelerado, frio (com ou sem solo), condutividade elétrica e emergência de plântulas em campo. Pôde-se concluir que: o controle da temperatura e umidade relativa do ar do ambiente de armazenamento, principalmente da umidade relativa do ar (câmara seca), favorece a conservação da qualidade das sementes

Análisis semicuantitativo del calcio y fósforo en el esmalte y la dentina

Existe una serie de características comunes asociadas al proceso biológico de formación de los tejidos calcificados a pesar de que los productos finales sean estructuralmente distintos. La presente investigación tiene como propósito determinar si la ratio Ca/P ratio es la misma para los tejidos calcificados dentales tanto del feto como del adulto y si dicha ratio es diferente al valor de la ratio Ca/P de la hidroxiapatita pura calculada por estequiometría. Se escogió como material de observación el esmalte y la dentina, en muestras de fetos humanos y en un total de 30 ratas adultas de raza Wistar y 20 dientes humanos sanos. Las observaciones se llevaron a cabo por medio de Microscopia Electrónica de Barrido y Microanálisis por separación de energía de rayos X. Los valores totales de la ratio Ca/P para el esmalte oscilaron en un intervalo de 0,9 y 1,2, con una media que se encuentra entre 1,07 y 1,08. Los valores totales de la ratio Ca/P para la dentina oscilan entre 1,03 y 1,12 y la media entre 1,07 y 1,075. No se encontraron diferencias estadísticamente significativas entre esmalte fetal y adulto ni entre la dentina fetal y adulta. Aún no pudiendo definir la existencia de precursores específicos en los tejidos calcificados del diente (esmalte y dentina), nuestros resultados sugieren que no toda la cristalización de estos tejidos corre a cargo de la hidroxiapatita sino que deben haber otros compuestos que expliquen la disminución del valor de la ratio Ca/P en las muestras estudiadas

Análisis semicuantitativo del calcio y fósforo en los tejidos calcificados de la mandíbula

El objetivo de nuestra investigación es realizar un estudio microanalítico semicuantitativo del calcio y el fósforo en los tejidos calcificados de la mandíbula. Dentro de este estudio se pretende calcular el valor de la ratio Ca/P por métodos semicuantitativos y compararlo con los valores estequiométricos de la ratio Ca/P de la hidroxiapatita referidos en la literatura; conocer los valores de la ratio Ca/P obtenidos para el tejido condroide, el hueso lamelar, el hueso fibrorreticular y el cartílago calcificado en las muestras fetales, por una parte, y adultas, por otra; y si existen o no diferencias significativas en la proporción Ca/P obtenidos para feto y adulto. El análisis morfológico de los tejidos calcificados fue realizado por medio de Microrradiografía Electrónica de Barrido (MEB) por electrones retrodispersados (Backscattering), y los resultados permiten afirmar que la ratio obtenida por análisis semicuantitativo mediante dispersión de rayos X de los tejidos calcificados (condroide, hueso lamelar y fibrorreticular) se encuentra más próxima a 1, y que no existen diferencias significativas entre las muestras fetales y de adulto en los tejidos analizados