Mapping for the future: Business intelligence tool to map regional housing stock

The amount of data available and the lack of data integration represent an increasing challenge to effective planning for government agencies. Integration of data from multiple sources has the potential to enable a user to draw valuable insights, which can be used to enhance service targeting and delivery, and to improve program evaluation. In recognition of the need to improve data integration the University of Wollongong and the NSW Office of Environment and Heritage (OEH) partnered to create an integrated housing stock database for the Illawarra region. The database serves as the backbone for an online and interactive Housing Stock Mapping Dashboard (HSMD). It assembled multilevel granular information (including at the Statistical Area Level 1 (SA1) and Local Government Area (LGA) level) collected from multiple historical programs by multiple agencies. This centralised, integrated data repository can help agencies understand the existing housing stock, and improve access to information to support evidence-based policy. This paper presents a model of how data can be integrated from multiple agencies to provide an online collaboration platform. The platform, HSMD, was designed to demonstrate to government, industry, and the research community the opportunity of data integration and advanced analytics. Potential applications of the HSMD include characterisation of the existing housing stock according to a range of building attributes, for instance the presence of ceiling insulation or rainwater tanks. Comparison of these attributes with energy consumption data can indicate the influence of the attribute, or the impact of a specific intervention. This can help policy makers understand uptake and penetration of previous rebate schemes

Immobilization of fungal biomass with multi-walled carbon nanotubes as biosorbent

Aim: This study was mainly highlighted on a combination of fungal biomass onto MWCNTs in order to enhance the positive integration of impurities removal in aqueous solution. Methodology and results: The immobilization of fungal biomass and MWCNTs was done in a batch liquid medium with several factors such as agitation speed, dose of MWCNTs, pH and inoculum dosage that were conducted with one factor at one time (OFAT) method. Basically, to verify the functional group of MWCNTs, Aspergillus niger biomass and immobilized A. niger biomass, the FTIR was applied and FESEM was done to demonstrate and compare the image of the immobilized A. niger biomass with MWCNTs and fungal biomass alone. The finding showed the best agitation speed, dose of MWCNTs, pH and inoculum dosage were 150 rpm, 0.5 g, 5-6 and 2% respectively. FTIR indicates the presents of the functional groups like –OH (3270 cm -1 ), C-O (1619 cm -1 ) and –CH (2915 cm -1 ) while FESEM illustrates the images of the wrapped MWCNTs on A. niger biomass. Conclusion, significance and impact of study: The conventional technique of adsorption of fungal biomass alone not showing a favorable removal of impurities. Thus, the immobilization of fungal biomass (A. niger) with multi-walled carbon nanotubes (MWCNTs) was a good combination since both have potential functional group to accumulate to each other and has a tendency to remove effectively and efficiently the impurities in aqueous solution

Serum Vitamin D and Vaspin Levels Among Patients with Acute Myocardial Infarction and Their Association with Risk Factors

Mukhtiar Baig,1 Kamal Waheeb Alghalayini,2 Zohair Jamil Gazzaz,3 Manal Abdulaziz Murad4 1Department of Clinical Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Internal Medicine, Consultant Cardiologist, King Abdulaziz University Hospital, Jeddah, Saudi Arabia; 3Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 4Department of Family and Community Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Mukhtiar Baig, Department of Clinical Biochemistry, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia, Tel +966581083289, Email [email protected]: The current study investigated and compared serum levels of vitamin D (VD) and vaspin in AMI patients and healthy subjects and correlated these biomarkers with other biochemical risk factors for AMI.Patients and Methods: The research was carried out at King Abdulaziz University Hospital (KAUH) in Jeddah. Blood samples and additional information were gathered from 110 admitted AMI patients in the Intensive Coronary Care Unit (ICCU) (ages 40– 65 years) and 50 adult, healthy volunteers whose BMI and age were similar to those of the patients.Results: AMI patients had significantly lower vaspin (p 20 - < 30 ng/mL), and 35 (31.8%) had sufficient levels (≥ 30 ng/mL). In healthy subjects, VD levels were deficient in 4(8%), insufficient in 13 (26%), and sufficient in 33 (66%). VD insufficiency was more prevalent in AMI patients compared to the healthy group (54.5% vs 26%; p < 0.001). In AMI patients, serum vaspin was found to be related to age and HbA1c in the control group. VD did not show a significant correlation with any variable in AMI patients and healthy subjects. Serum vaspin (p = 0.89) and VD levels (p = 0.29) did not differ significantly between female and male control groups.Conclusion: Compared to the healthy group, AMI patients showed significantly lower vaspin and VD levels. Additionally, AMI patients had a higher prevalence of VD deficiency and insufficiency, suggesting its possible role in the occurrence of AMI.Keywords: vitamin D, vaspin, myocardial infarction, BMI, vitamin D deficiency, HDL-

Antimicrobial potential of alkaloids and flavonoids extracted from Tamarix aphylla leaves against common human pathogenic bacteria

Background: Alkaloids and flavonoids are secondary metabolites extracted from different medicinal plants. Tamarix aphylla a traditionally valuable medicinal plant; was used for the extraction of alkaloids and flavonoids in order to evaluate their antibacterial activity.Methodology: The leaves of the plant were collected from district Kohat, Pakistan, and their alkaloids and flavonoids were extracted with ethanol and methanol, respectively. Four bacteria i.e. Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa) were selected for the biological screening of these phyto-constituents.Results: The concentration of alkaloids was found to be more in the leaves of Tamarix aphylla than flavonoids. The extracted phytochemicals showed varied inhibition zones against tested bacterial isolates. Alkaloids showed highest inhibitory activity against Staphylococcus aureus (14±0.6 mm) followed by Pseudomonas aeruginosa (13±0.7 mm). Conversely, flavonoids showed the highest inhibitory affect against Salmonella typhi (17±0.7 mm) followed by Staphylococcus aureus (14±0.7 mm). However, both extracts showed the lowest inhibitory effects against Escherichia coli.Conclusions: It was concluded that the alkaloids and flavonoids from Tamarix aphylla leaves have antimicrobial potential against common human bacterial pathogens. However, flavonoids were found to be more active phytochemical against tested bacterial strains as compared to alkaloids.Keywords: Kohat; Medicinal plants; Phytochemical screening; In-vitro activity; Bacterial strains

The methodological and reporting quality of systematic reviews from China and the USA are similar

Objective: To compare the methodological and reporting quality of systematic reviews by authors from China and those from the United States (the USA). Study Design: From systematic reviews of randomised trials published in 2014 in English, we randomly selected 100 from China and 100 from the USA. The methodological quality was assessed using the AMSTAR tool, and reporting quality assessed using the PRISMA tool. Results: Compared with systematic reviews from the USA, those from China were more likely to be a meta-analysis, published in low impact journals, and a non-Cochrane review. The mean summary AMSTAR score was 6.7 (95% confidence interval: 6.5 to 7.0) for reviews from China and 6.6 (6.1 to 7.1) for reviews from the USA, and the mean summary PRISMA score was 21.2 (20.7 to 21.6) for reviews from China and 20.6 (19.9 to 21.3) for reviews from the USA. The differences in summary quality scores between China and the USA were statistically non-significant after adjusting for multiple review factors. Conclusions: The overall methodological and reporting quality of systematic reviews by authors from China are similar to those from the USA, although the quality of systematic reviews from both countries could be further improved

Supercruiser Arrow HS-8

Technology in aeronautics has advanced dramatically since the last design of a production High Speed Civil Transport (HSCT) aircraft. Newly projected requirements call for a new High Speed Civil Transport aircraft with a range of approximately 550 nm and at least 275 passenger capacity. The aircraft must be affordable and marketable. The new HSCT must be able to sustain long-duration flights and to absorb the abuse of daily operation. The new aircraft must be safe and simple to fly and require a minimum amount of maintenance. This aircraft must meet FAA certification criteria of FAR Part 25 and environmental constraints. Several design configurations were examined and two designs were selected for further investigation. The first design employs the delta planform wings and conventional empennage layout. The other design uses a swing wing layout and conventional empennage. Other engineering challenges, including materials and propulsion are also discussed. At a cruise flight speed between Mach 2.2 and Mach 3.0, no current generation of materials can endure the thermal loading of supersonic flight and satisfy the stringent weight requirements. A new generation of lightweight composite materials must be developed for the HSCT. With the enforcement of stage 3 noise restrictions, these new engines must be able to propel the aircraft and satisfy the noise limit. The engine with the most promise is the variable cycle engine. At low subsonic speeds the engine operates like a turbofan engine, providing the most efficient performance. At higher speeds the variable cycle engine operates as a turbojet power plant. The two large engine manufacturers, General Electric and Pratt & Whitney in the United States, are combining forces to make the variable cycle engine a reality

The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer

Two oral fluoropyrimidine therapies have been introduced for metastatic colorectal cancer. One is a 5-fluorouracil pro-drug, capecitabine; the other is a combination of tegafur and uracil administered together with leucovorin. The purpose of this study was to compare the clinical effectiveness and cost-effectiveness of these oral therapies against standard intravenous 5-fluorouracil regimens. A systematic literature review was conducted to assess the clinical effectiveness of the therapies and costs were calculated from the UK National Health Service perspective for drug acquisition, drug administration, and the treatment of adverse events. A cost-minimisation analysis was used; this assumes that the treatments are of equal efficacy, although direct randomised controlled trial (RCT) comparisons of the oral therapies with infusional 5-fluorouracil schedules were not available. The cost-minimisation analysis showed that treatment costs for a 12-week course of capecitabine (£2132) and tegafur with uracil (£3385) were lower than costs for the intravenous Mayo regimen (£3593) and infusional regimens on the de Gramont (£6255) and Modified de Gramont (£3485) schedules over the same treatment period. Oral therapies result in lower costs to the health service than intravenous therapies. Further research is needed to determine the relative clinical effectiveness of oral therapies vs infusional regimens