Reducing Urban Pollution Exposure from Road Transport(RUPERT)

This paper presents the preliminary results of a two-year study on reducing urban pollution exposure from road transport (RUPERT). The main aim of this project is to develop a new modelling framework for nitrogen dioxide, carbon monoxide and particulate matter to simulate exposures of different population groups across a city, and to assess the impact of roadside concentrations on these exposures. This will be achieved by modelling the frequency distribution of personal exposures (PEFDs) as a function of urban background and roadside concentrations, under different traffic conditions. The modelling approach combines new and existing models relating traffic and air pollution data, with particular emphasis of the impact of congestion, and the probabilistic modelling framework of personal exposure. Modelling of roadside concentrations consists of two main elements, namely the analysis of concentrations patterns at different roadside sites and of the relationship between traffic conditions and added roadside pollution. Roadside concentrations are predicted using empirically derived relationships; statistical models, novel statistics and artificial neural networks namely feed forward neural network and radial basis neural network. The exposure modelling is carried out by linking two models: the INDAIR model, which is designed to simulate probabilistically diurnal profiles of air pollutant concentrations in a range of microenvironments, and the EXPAIR model, which is designed to simulate population exposure patterns based on population time-activity patterns and a library of micro-environmental concentrations derived from the INDAIR model

Cause of death and predictors of mortality in a community-based cohort of people with epilepsy.

OBJECTIVE: The risk of premature mortality is increased in people with epilepsy. The reasons for this and how it may relate to epilepsy etiology remain unclear. METHODS: The National General Practice Study of Epilepsy is a prospective, community-based cohort that includes 558 people with recurrent unprovoked seizures of whom 34% died during almost 25 years of follow-up. We assessed the underlying and immediate causes of death and their relationship to epilepsy etiology. Psychiatric and somatic comorbidities of epilepsy as predictors of mortality were scrutinized using adjusted Cox proportional hazards models. RESULTS: The 3 most common underlying causes of death were noncerebral neoplasm, cardiovascular, and cerebrovascular disease, accounting for 59% (111/189) of deaths, while epilepsy-related causes (e.g., sudden unexplained death in epilepsy) accounted for 3% (6/189) of deaths. In 23% (43/189) of individuals, the underlying cause of death was directly related to the epilepsy etiology; this was significantly more likely if death occurred within 2 years of the index seizure (percent ratio 4.28 [95% confidence interval 2.63-6.97]). Specific comorbidities independently associated with increased risk of mortality were neoplasms (primary cerebral and noncerebral neoplasm), certain neurologic diseases, and substance abuse. CONCLUSIONS: Comorbid diseases are important causes of death, as well as predictors of premature mortality in epilepsy. There is an especially strong relationship between cause of death and epilepsy etiology in the first 2 years after the index seizure. Addressing these issues may help stem the tide of premature mortality in epilepsy

Choosing Appropriate Power System Simulation Models for Different Events

This report forms a discussion relating to what types of power system models there are and what software packages are available to investigate different power system phenomena. The responses which might emerge to perturbations to the power system are tabulated to provide examples of Automatic and Manual interventions – that is, responses which can emerge endogenously from the system or those which can be controlled by human operators over different timescales. Similarly, the types of simulation models which could be used to investigate these different aspects are described and how they may interact or be leveraged in a wider-ranging resilience assessment. These are categorised based on being either Initial Condition Simulators that allow a range of different system conditions to be postulated, defined in such a way as to allow subsequent assessment of the impact of disturbances, or Power System Perturbation Simulators such as dynamic simulators which model the impacts of disturbances on these original conditions, such as short circuits or loss of generation infeed

Changes in soil organic matter, plant nutrients and system productivity under conservation agricultural practices in the rice-jute cropping system

Soil organic matter (SOM) is central to soil quality and nutrient cycling. In Bangladesh, depletion of soil fertility is a serious threat to sustainability of agricultural production due to high cropping intensity and agriculture practices based on conventional tillage and residue removal (Rijpma and Jahiruddin, 2004). In this situation, CA practices (minimum tillage, crop residue retention and diverse crop rotations) could be a good option for the improvement of soil quality and crop productivity in Bangladesh. However, CA practices are poorly developed for intensive rice-based cropping system and their effect on SOM, plant nutrients and system productivity have not yet been properly addressed. Hence, the present study was undertaken to monitor the changes in SOM and other plant nutrients with system productivity under CA practices in the rice-jute cropping system in the Low Ganges River Floodplain of Bangladesh

Strip planting decreases nitrogen fertilizer requirements while retention of more residue increases them in a rice - wheat - mungbean sequence on a subtropical floodplain soil

Conservation agriculture (CA) has not been well developed for intensively cultivated (2-3 crops yr-1) rice- based cropping systems which produce large amounts of crop residues annually. Thus, we examined the effects of two crop establishment systems (minimum soil disturbance by strip planting (SP) or conventional tillage (CT)), two residue retention levels (low and high) and five N rates (60, 80, 100, 120 & 140% of the recommended N fertilizer doses (RFD) on nine consecutive crops on an Aeric Haplaquept under rice-wheat- mungbean sequence. Rice yields were comparable between the crop establishment types but system yields were significantly higher with SP in two out of three years compare to CT. Increased residue retention did not significantly influence rice yield but positively influenced system yields. No substantial differences in optimum N rate was estimated between CT and SP for 90% of maximum yield goal (MYG) for all the three years but substantially decreased in SP compared to CT in two out of three years for 95 and 99% of MYG. The N fertilizer requirement was 6-22% higher with high residue retention compared to low residue retention plots for all the three yield goal levels. High residue retention also increased soil organic carbon (SOC) at 0- 6 cm depth in both tillage treatments. In conclusion, introducing CA did not alter the N fertilizer requirements of rice for 90% of MYG but reduced the requirement for 95 and 99% of MYG compared to CT. However, there was evidence that the retained crop residue immobilized N and increased the fertilizer N requirement

The effect of Nb on the corrosion and hydrogen pick-up of Zr alloys

Abstract Zr-Nb alloys are known to perform better in corrosion and hydrogen pick-up than other Zr alloys but the mechanism by which this happens is not well understood. Atomistic simulations using density functional theory of both tetragonal and monoclinic ZrO2 were performed, with intrinsic defects and Nb dopants. The overall defect populations with respect to oxygen partial pressure were calculated and presented in the form of Brouwer diagrams. Nb is found to favour 5 + in monoclinic ZrO2 at all partial pressures, but can exist in oxidation states ranging from 5 + to 3 + in the tetragonal phase. Nb5+ is charge balanced by Zr vacancies in both phases, suggesting that contrary to previous assumptions, Nb does not act as an n-type dopant in the oxide layer. Clusters containing oxygen vacancies were considered, Nb2+ was shown to exist in the tetragonal phase with a binding energy of 2.4 eV. This supports the proposed mechanism whereby low oxidation state Nb ions (2 + or 3+) charge balance the build-up of positive space-charge in the oxide layer, increasing oxygen vacancy and electron mobility, leading to near-parabolic corrosion kinetics and a reduced hydrogen pick-up. Previous experimental work has shown that tetragonal ZrO2 transforms to the monoclinic phase during transition, and that during transition a sharp drop in the instantaneous hydrogen pick-up fraction occurs. The oxidation of lower charge state Nb defects to Nb5+ during this phase change, and the consequent temporary n-doping of the oxide layer, is proposed as an explanation for the drop in hydrogen pick-up during transition

Selective biocatalytic hydroxylation of unactivated methylene C-H bonds in cyclic alkyl substrates

The cytochrome P450 monooxygenase CYP101B1 from Novosphingobium aromaticivorans selectively hydroxylated methylene C-H bonds in cycloalkyl rings. Cycloketones and cycloalkyl esters containing C6, C8, C10 and C12 rings were oxidised with high selectively on the opposite side of the ring to the carbonyl substituent. Cyclodecanone was oxidised to oxabicycloundecanol derivatives in equilibrium with the hydroxycyclodecanones.Md Raihan Sarkar, Samrat Dasgupta, Simon M. Pyke and Stephen G. Bel

The effect of Nb on the corrosion and hydrogen pick-up of Zr alloys

Abstract Zr-Nb alloys are known to perform better in corrosion and hydrogen pick-up than other Zr alloys but the mechanism by which this happens is not well understood. Atomistic simulations using density functional theory of both tetragonal and monoclinic ZrO2 were performed, with intrinsic defects and Nb dopants. The overall defect populations with respect to oxygen partial pressure were calculated and presented in the form of Brouwer diagrams. Nb is found to favour 5 + in monoclinic ZrO2 at all partial pressures, but can exist in oxidation states ranging from 5 + to 3 + in the tetragonal phase. Nb5+ is charge balanced by Zr vacancies in both phases, suggesting that contrary to previous assumptions, Nb does not act as an n-type dopant in the oxide layer. Clusters containing oxygen vacancies were considered, Nb2+ was shown to exist in the tetragonal phase with a binding energy of 2.4 eV. This supports the proposed mechanism whereby low oxidation state Nb ions (2 + or 3+) charge balance the build-up of positive space-charge in the oxide layer, increasing oxygen vacancy and electron mobility, leading to near-parabolic corrosion kinetics and a reduced hydrogen pick-up. Previous experimental work has shown that tetragonal ZrO2 transforms to the monoclinic phase during transition, and that during transition a sharp drop in the instantaneous hydrogen pick-up fraction occurs. The oxidation of lower charge state Nb defects to Nb5+ during this phase change, and the consequent temporary n-doping of the oxide layer, is proposed as an explanation for the drop in hydrogen pick-up during transition