16 research outputs found
Twelve-month outcomes of 400 patients treated with a resorbable metal scaffold: insights from the BIOSOLVE-IV registry
Simulation of dimensionality effects in thermal transport
The discovery of nanostructures and the development of growth and fabrication
techniques of one- and two-dimensional materials provide the possibility to
probe experimentally heat transport in low-dimensional systems. Nevertheless
measuring the thermal conductivity of these systems is extremely challenging
and subject to large uncertainties, thus hindering the chance for a direct
comparison between experiments and statistical physics models. Atomistic
simulations of realistic nanostructures provide the ideal bridge between
abstract models and experiments. After briefly introducing the state of the art
of heat transport measurement in nanostructures, and numerical techniques to
simulate realistic systems at atomistic level, we review the contribution of
lattice dynamics and molecular dynamics simulation to understanding nanoscale
thermal transport in systems with reduced dimensionality. We focus on the
effect of dimensionality in determining the phononic properties of carbon and
semiconducting nanostructures, specifically considering the cases of carbon
nanotubes, graphene and of silicon nanowires and ultra-thin membranes,
underlying analogies and differences with abstract lattice models.Comment: 30 pages, 21 figures. Review paper, to appear in the Springer Lecture
Notes in Physics volume "Thermal transport in low dimensions: from
statistical physics to nanoscale heat transfer" (S. Lepri ed.
Effect of peripheral substitution on the optical limiting properties of zinc phthalocyanines
10.1117/12.452090Proceedings of SPIE - The International Society for Optical Engineering4798222-228PSIS
Influence of axial substitution on the optical limiting properties of indium porphyrins
10.1117/12.451927Proceedings of SPIE - The International Society for Optical Engineering4798195-202PSIS
BIOSOLVE-IV-registry: Safety and performance of the Magmaris scaffold: 12-month outcomes of the first cohort of 1,075 patients
Objectives: We aimed to assess the safety and performance of the Magmaris sirolimus-eluting bioresorbable magnesium scaffold in a large patient population. Background: Magmaris has shown good outcomes in small-sized controlled trials, but further data are needed to confirm its usability, safety, and performance. Methods: BIOSOLVE-IV is an international, single arm, multicenter registry including patients with a maximum of two single de novo lesions. Follow-up is scheduled up to 5 years; the primary outcome is target lesion failure (TLF) at 12 months. Results: A total of 1,075 patients with 1,121 lesions were enrolled. Mean patient age was 61.3 \ub1 10.5 years and 19.2% (n = 206) presented with non-ST-elevation myocardial infarction (NSTEMI). Lesions were 3.2 \ub1 0.3 mm in diameter and 14.9 \ub1 4.2 mm long; 5.1% (n = 57) were bifurcation lesions. Device success was 97.3% (n = 1,129) and procedure success 98.9% (n = 1,063). The Kaplan\u2013Meier estimate of TLF at 12 months was 4.3% [95% confidence interval, CI: 3.2, 5.7] consisting of 3.9% target lesion revascularizations, 0.2% cardiac death, and 1.1% target-vessel myocardial infarction. Definite/probable scaffold thrombosis occurred in five patients (0.5% [95% CI: 0.2, 1.1]), thereof four after early discontinuation of antiplatelet/anticoagulation therapy. Conclusion: BIOSOLVE-IV confirms the safety and performance of the Magmaris scaffold in a large population with excellent device and procedure success and a very good safety profile up to 12 months in a low-risk population
Global translation during early development depends on the essential transcription factor PRDM10
10.1038/s41467-020-17304-3Nature Communications111360