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Critical current measurements of ISABELLE superconducting cables
Short sample critical measurements on ISABELLE superconducting cables are described. The purpose is to provide a basis for assessing magnet performance and to provide Quality Assurance data on materials purchases. The measurements are made on 1 m samples in a dipole magnet. Voltages on the V-I curve are determined to a precision of several tenths of a microvolt. The critical current is defined as that at which rho = 1 x 10/sup -12/..cap omega..cm/sup 1/ and is determined to a precision of 1 to 2%. Similar techniques are employed in determining the critical currents of the wires of which the cables are made. The relation between cable and wire critical currents will be discussed. It is found that well insulated, slowly ramped cables of the ISABELLE design are stable for currents up to approximately rho = 2 x 10/sup -12/..cap omega..cm. The value of current corresponding to the resistivity determines the limit of magnet performance. Additional properties of the cabled conductors such as the normal state resistance and the longitudinal quench propagation velocity are also measured
センシ
In Persian; foreword in Japanese and EnglishAdded t.p. in Japanese and Englishجلد 2 published in 2006 before جلد 1Two col. maps on folded leaves of plates inserted in جلد 1"Supported by Grant-in-Aid for Scientific Research (Grant-in-Aid for JSPS Fellows, 17-2387, 2005-2008 and Grant-in-Aid for Young Scientists (B), 21720255, 2009)"--Foreword, جلد 1, p. xviiIncludes bibliographical references and inde
The Opportunity Cost of the Conservation Reserve Program: A Kansas Land Example
The effects of the Conservation Reserve Program (CRP) on farmland values is investigated using a set of parcel-level data for land sales in Kansas over the period 1998 to 2014. The sales data are used to estimate a hedonic model of land values that allows for the opportunity cost of CRP enrollment to vary across space and time. Factors impacting the opportunity costs include the relative productivity of land, returns to farming, and the time remaining under the CRP contracts. We find that the discount associated with having land under CRP contract averages 7%
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected 124 mosaic X events 42 Mb in 97 (0.25%) women. Here we show rates for X-chromosome mosaicism are four times higher than mean autosomal rates; X mosaic events more often include the entire chromosome and participants with X events more likely harbour autosomal mosaic events. X mosaicism frequency increases with age (0.11% in 50-year olds; 0.45% in 75-year olds), as reported for Y and autosomes. Methylation array analyses of 33 women with X mosaicism indicate events preferentially involve the inactive X chromosome. Our results provide further evidence that the sex chromosomes undergo mosaic events more frequently than autosomes, which could have implications for understanding the underlying mechanisms of mosaic events and their possible contribution to risk for chronic diseasesMitchell J. Machiela, Weiyin Zhou, Eric Karlins, Joshua N. Sampson, Neal D. Freedman ... Luis Perez-Jurado ... et al
A pressure drop correlation for low Reynolds number Newtonian flows through a rectangular orifice in a similarly shaped micro-channel
Current microfabrication methods mean that rectangular orifices in similarly shaped micro-channels are often found in microfluidic devices. The power required to overcome the pressure drop across such orifices is often of importance. In the contribution reported here, numerical results for low Reynolds number incompressible Newtonian fluid flow through rectangular orifice in similarly shaped micro-channel have been used to develop a correlation for pressure drop arising from the orifice. The correlation, which was motivated by theoretical developments, indicates that the pressure drop is proportional to the average velocity through the orifice, and a function of the orifice contraction ratio, length-to-width ratio and, most particularly, aspect ratio.V. Zivkovic, P. Zerna, Z.T. Alwahabi, M.J. Bigg
Effects of Intermittent IL-2 Alone or with Peri-Cycle Antiretroviral Therapy in Early HIV Infection: The STALWART Study
The Study of Aldesleukin with and without antiretroviral therapy (STALWART) evaluated whether intermittent interleukin-2 (IL-2) alone or with antiretroviral therapy (ART) around IL-2 cycles increased CD4+ counts compared to no therapy
Parental origin of sequence variants associated with complex diseases
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldEffects of susceptibility variants may depend on from which parent they are inherited. Although many associations between sequence variants and human traits have been discovered through genome-wide associations, the impact of parental origin has largely been ignored. Here we show that for 38,167 Icelanders genotyped using single nucleotide polymorphism (SNP) chips, the parental origin of most alleles can be determined. For this we used a combination of genealogy and long-range phasing. We then focused on SNPs that associate with diseases and are within 500 kilobases of known imprinted genes. Seven independent SNP associations were examined. Five-one with breast cancer, one with basal-cell carcinoma and three with type 2 diabetes-have parental-origin-specific associations. These variants are located in two genomic regions, 11p15 and 7q32, each harbouring a cluster of imprinted genes. Furthermore, we observed a novel association between the SNP rs2334499 at 11p15 and type 2 diabetes. Here the allele that confers risk when paternally inherited is protective when maternally transmitted. We identified a differentially methylated CTCF-binding site at 11p15 and demonstrated correlation of rs2334499 with decreased methylation of that site.info:eu-repo/grantAgreement/EC/FP7/21807
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