226 research outputs found

    Presidential Emergency Powers related to International Economic Transactions

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    On December 28, 1977, President Carter signed into law Public Law 95-223, an act [w]ith respect to the powers of the President in time of war or national emergency. The primary purpose of the Act is to revise the Trading With the Enemy Act of 1917 (TWEA), and thus to restrict presidential authority to respond to emergencies related to international economic transactions. The Act is the latest product of a continuing congressional effort to readjust the balance of power between the two branches of government. The War Powers Resolution and the National Emergencies Act were earlier pieces of legislation intended to have the same effect: to retrieve congressional power which had been relinquished to the President. The question remains, however, whether Congress can reverse a trend toward greater presidential initiative, a trend which until recently it supported. The Trading With the Enemy Act is a prime example of how presidential initiative has been nurtured and expanded by presidential action and congressional acquiescence. The Act was originally intended to provide the President with the authority to respond to international economic emergencies during time of war; it evolved into the source of authority for presidential responses in such diverse areas as consumer credit, postal strikes, and balance of payments deficits. The purpose of this paper is to analyze the concept, development, and scope of the powers delegated to the President under section 5(b) of the TWEA, and to determine what impact Public Law 95-223 will have on the use of these powers in future emergencies. This paper proposes that Congress has, indeed, chosen other roles for itself, and as a result that the constitutional authority of the President has expanded implicitly to include the authority to respond unilaterally to an emergency relating to international economic transactions. The significance of Public Law 95-223 is reflected in the seemingly disparate reactions of the executive and legislative branches towards the Act: President Carter stated that Public Law 95-223 is largely procedural; Congress stated that it intended the legislation to redefine the power of the President to regulate economic transactions in future times of war or national emergency. The evidence indicates, however, that while Congress may have redefined the power, it did not substantively change the power by that redefinition

    On the vanishing viscosity limit in a disk

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    We say that the solution u to the Navier-Stokes equations converges to a solution v to the Euler equations in the vanishing viscosity limit if u converges to v in the energy norm uniformly over a finite time interval. Working specifically in the unit disk, we show that a necessary and sufficient condition for the vanishing viscosity limit to hold is the vanishing with the viscosity of the time-space average of the energy of u in a boundary layer of width proportional to the viscosity due to modes (eigenfunctions of the Stokes operator) whose frequencies in the radial or the tangential direction lie between L and M. Here, L must be of order less than 1/(viscosity) and M must be of order greater than 1/(viscosity)

    Bohmian mechanics, the quantum-classical correspondence and the classical limit: the case of the square billiard

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    Square billiards are quantum systems complying with the dynamical quantum-classical correspondence. Hence an initially localized wavefunction launched along a classical periodic orbit evolves along that orbit, the spreading of the quantum amplitude being controlled by the spread of the corresponding classical statistical distribution. We investigate wavepacket dynamics and compute the corresponding de Broglie-Bohm trajectories in the quantum square billiard. We also determine the trajectories and statistical distribution dynamics for the equivalent classical billiard. Individual Bohmian trajectories follow the streamlines of the probability flow and are generically non-classical. This can also hold even for short times, when the wavepacket is still localized along a classical trajectory. This generic feature of Bohmian trajectories is expected to hold in the classical limit. We further argue that in this context decoherence cannot constitute a viable solution in order to recover classicality.Comment: Figures downgraded to low resolution; To be published in Found. Phys. (2009)

    The half-lives for 24Na, 72Ga and 140La

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22610/1/0000160.pd

    Ab initio Quantum and ab initio Molecular Dynamics of the Dissociative Adsorption of Hydrogen on Pd(100)

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    The dissociative adsorption of hydrogen on Pd(100) has been studied by ab initio quantum dynamics and ab initio molecular dynamics calculations. Treating all hydrogen degrees of freedom as dynamical coordinates implies a high dimensionality and requires statistical averages over thousands of trajectories. An efficient and accurate treatment of such extensive statistics is achieved in two steps: In a first step we evaluate the ab initio potential energy surface (PES) and determine an analytical representation. Then, in an independent second step dynamical calculations are performed on the analytical representation of the PES. Thus the dissociation dynamics is investigated without any crucial assumption except for the Born-Oppenheimer approximation which is anyhow employed when density-functional theory calculations are performed. The ab initio molecular dynamics is compared to detailed quantum dynamical calculations on exactly the same ab initio PES. The occurence of quantum oscillations in the sticking probability as a function of kinetic energy is addressed. They turn out to be very sensitive to the symmetry of the initial conditions. At low kinetic energies sticking is dominated by the steering effect which is illustrated using classical trajectories. The steering effects depends on the kinetic energy, but not on the mass of the molecules. Zero-point effects lead to strong differences between quantum and classical calculations of the sticking probability. The dependence of the sticking probability on the angle of incidence is analysed; it is found to be in good agreement with experimental data. The results show that the determination of the potential energy surface combined with high-dimensional dynamical calculations, in which all relevant degrees of freedon are taken into account, leads to a detailed understanding of the dissociation dynamics of hydrogen at a transition metal surface.Comment: 15 pages, 9 figures, subm. to Phys. Rev.

    An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

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    For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

    Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.

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    Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools. We identified a total of 25,664 fusions, with a 63% validation rate. Integration of gene expression, copy number, and fusion annotation data revealed that fusions involving oncogenes tend to exhibit increased expression, whereas fusions involving tumor suppressors have the opposite effect. For fusions involving kinases, we found 1,275 with an intact kinase domain, the proportion of which varied significantly across cancer types. Our study suggests that fusions drive the development of 16.5% of cancer cases and function as the sole driver in more than 1% of them. Finally, we identified druggable fusions involving genes such as TMPRSS2, RET, FGFR3, ALK, and ESR1 in 6.0% of cases, and we predicted immunogenic peptides, suggesting that fusions may provide leads for targeted drug and immune therapy
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