Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment

LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7 tonnes, LZ will search primarily for low-energy interactions with weakly interacting massive particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000 live day run using a 5.6-tonne fiducial mass, LZ is projected to exclude at 90% confidence level spin-independent WIMP-nucleon cross sections above 1.4 × 10-48cm2 for a 40 GeV/c2 mass WIMP. Additionally, a 5σ discovery potential is projected, reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of 2.3 × 10−43 cm2 (7.1 × 10−42 cm2) for a 40 GeV/c2 mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020

Shell growth and oxygen isotopes in the topshell Osilinus urbinatus : resolving past inshore sea surface temperatures

Shells of the rocky shore intertidal gastropod Osilinus turbinatus (von Born), often abundant in archaeological deposits in the Mediterranean region, are a potential source of data on palaeotemperature, palaeoseasonality and archaeological seasonality. To evaluate this species as a climate archive, investigations of annual patterns of shell growth and of monthly variations in oxygen isotopes in shell carbonates were made on different populations in NW Sicily. Mark-recapture experiments at San Vito lo Capo and Mazzaforno show that O. turbinatus grows almost continuously throughout the year but at different rates in different seasons. Around 75% of the yearly shell growth occurs in the autumn and winter. On average, larger/older shells produce narrower annual growth increments than smaller/younger ones. Conspicuous growth lines in larger/older shells show that growth stops during the hottest part of the summer. Oxygen isotope analyses on monthly collected shells of O. turbinatus from three shores (Cala Grande, Monte Cofano and Mazzaforno) show that the isotope values record temperature variations through the year. In all the datasets, surface seawater temperatures (SSTs) calculated from δ18OSHELL mostly underestimate measured SSTs, offsets being generally greater in summer. Minimum annual offsets range from 0.0°C to 0.7°C and maximum annual offsets from 3.1°C to 8.7°C. δ18OSHELL values fail to record temperatures higher than 25°C. Careful selection of shells to be analysed can reduce offsets between δ18OSHELL temperature estimates and measured SSTs for many parts of the year, except the hottest. Allowing for this, shells of O. turbinatus offer good potential as climate archives and for archaeological studies of seasonal patterns of human foraging for shellfish

Radiocarbon dating and isotope analysis on the purported Aurignacian skeletal remains from Fontana Nuova (Ragusa, Italy)

Proving voyaging at sea by Palaeolithic humans is a difficult archaeological task, even for short distances. In the Mediterranean, a commonly accepted sea crossing is that from the Italian Peninsula to Sicily by anatomically modern humans, purportedly of the Aurignacian culture. This claim, however, was only supported by the typological attribution to the Aurignacian of the lithic industries from the insular site of Fontana Nuova. AMS radiocarbon dating undertaken as part of our research shows that the faunal remains, previously considered Aurignacian, actually date to the Holocene. Absolute dating on dentinal collagen also attributes the human teeth from the site to the early Holocene, although we were unable to obtain ancient DNA to evaluate their ancestry. Ten radiocarbon dates on human and other taxa are comprised between 9910\u20139700 cal. BP and 8600\u20138480 cal. BP, indicating that Fontana Nuova was occupied by Mesolithic and not Aurignacian hunter-gatherers. Only a new study of the lithic assemblage could establish if the material from Fontana Nuova is a mixed collection that includes both late Upper Palaeolithic (Epigravettian) and Mesolithic artefacts, as can be suggested by taking into account both the results of our study and of the most recent reinterpretation of the lithics. Nevertheless, this research suggests that the notion that Aurignacian groups were present in Sicily should now be revised. Another outcome of our study is that we found that three specimens, attributed on grounds both of morphological and ZooMS identifications to Cervus elaphus, had \u3b4 13 C values significantly higher than any available for such species in Europe

Stuck to the shore? : investigating prehistoric hunter-gatherer subsistence, mobility and territoriality in a Mediterranean coastal landscape through isotope analyses on marine mollusc shell carbonates and human bone collagen

Subsistence and mobility strategies of hunter-gatherers in the Mediterranean Basin during the transition from the late Pleistocene to the early Holocene have been the object of few studies, even though its karst coastal regions have high densities of prehistoric sites. One such area is the territory of the Conca d’Oro in NW Sicily, which has numerous sites with faunal remains testifying to economies mainly based on hunting of terrestrial ungulates and on the regular consumption of molluscs. This paper presents results from the study of faunal remains from cave sites occupied by hunter-gatherers in the late Pleistocene and early Holocene, and of isotope analyses on shells of marine molluscs collected for food and on collagen from the bones of the hunter-gatherers buried in these caves. The mollusc assemblages are dominated by inter-tidal rocky shore species of the genera Patella and Osilinus, which from 16 to 9 kyrs cal BP were the principal marine resources exploited by the hunter-gatherers of the Conca d’Oro. Oxygen isotope analyses on shells of Osilinus turbinatus show that in the late Pleistocene the exploitation of marine molluscs at the Addaura caves, relatively close to the shoreline, was restricted to late autumn and winter, while at Grotta Niscemi, which is further inland, these resources were exploited less intensively but for longer in the year, from autumn to the early spring. The data from the shells (both isotope and biometrical) suggest that late Pleistocene hunter-gatherers spent the coldest months of the year close to the coast, moving inland in late spring and for the summer. In the early Holocene, by contrast, marine molluscs were exploited longer during the year, attesting to a change in mobility strategies and, probably, frequent moves within more restricted territories. Carbon and nitrogen isotopes in human bone collagen from Grotta Addaura Caprara and Grotta della Molara show that marine foods were marginal in the diets of both late Pleistocene and early Holocene hunter-gatherers. Overall, the data indicate that the territory of the Conca d’Oro hunter-gatherers probably extended from the coastal plain to the upland areas during the late Pleistocene, but became more restricted in the early Holocene. This model might have broader application to hunter-gatherer settlement systems in other karst coastal areas of the Mediterranean

Restricted spirometry in the burden of lung disease study

PubMedID: 22863565BACKGROUND: The presence of restrictive lung disease has classically required the measure of total lung capacity to document 'true' restriction, which has limited its detection in large population-based studies. METHODS: We used spirometric data to classify people with restricted spirometry (forced expiratory volume in 1 second [FEV1]/forced vital capacity ? 0.70 and FEV1 < 80% predicted) in the Burden of Lung Disease (BOLD) Study and determined the relation between this finding and demographic factors and the presence of chronic diseases, including diabetes mellitus, hypertension and cardiovascular disease. RESULTS: Overall, we found that 11.7% of men (546/ 4664) and 16.4% of women (836/5098) had restricted spirometry. Prevalence varied widely by site, from a low of 4.2% among males in Sydney, Australia, to a high of 48.7% among females in Manila, The Philippines. Compared to people with normal lung function, those with restricted spirometry had a higher prevalence of diabetes (12.2% vs. 4.6%), heart disease (15.0% vs. 7.7%) and hypertension (38.8% vs. 22.8%). CONCLUSIONS: Restricted spirometry is a common finding in population studies. Additional research is needed to better define and describe the mechanisms that lead to restricted spirometry and potential interventions. © 2012 The Union

Origin and Diet of the Prehistoric Hunter-Gatherers on the Mediterranean Island of Favignana (\uc8gadi Islands, Sicily)

Hunter-gatherers living in Europe during the transition from the late Pleistocene to the Holocene intensified food acquisition by broadening the range of resources exploited to include marine taxa. However, little is known on the nature of this dietary change in the Mediterranean Basin. A key area to investigate this issue is the archipelago of the \uc8gadi Islands, most of which were connected to Sicily until the early Holocene. The site of Grotta d'Oriente, on the present-day island of Favignana, was occupied by hunter-gatherers when Postglacial environmental changes were taking place (14,000-7,500 cal BP). Here we present the results of AMS radiocarbon dating, palaeogenetic and isotopic analyses undertaken on skeletal remains of the humans buried at Grotta d'Oriente. Analyses of the mitochondrial hypervariable first region of individual Oriente B, which belongs to the HV-1 haplogroup, suggest for the first time on genetic grounds that humans living in Sicily during the early Holocene could have originated from groups that migrated from the Italian Peninsula around the Last Glacial Maximum. Carbon and nitrogen isotope analyses show that the Upper Palaeolithic and Mesolithic hunter-gatherers of Favignana consumed almost exclusively protein from terrestrial game and that there was only a slight increase in marine food consumption from the late Pleistocene to the early Holocene. This dietary change was similar in scale to that at sites on mainland Sicily and in the rest of the Mediterranean, suggesting that the hunter-gatherers of Grotta d'Oriente did not modify their subsistence strategies specifically to adapt to the progressive isolation of Favignana. The limited development of technologies for intensively exploiting marine resources was probably a consequence both of Mediterranean oligotrophy and of the small effective population size of these increasingly isolated human groups, which made innovation less likely and prevented transmission of fitness-enhancing adaptations. \ua9 2012 Mannino et al

Did Neandertals and Anatomically Modern Humans coexist in Northern Italy during the MIS 3?

The main processes invoked to explain the demise of Homo neanderthalensis are the effects of adverse climatic conditions in the northern hemisphere during Marine Isotope Stage 3 (MIS 3) and the outcome of the interaction with Anatomically Modern Humans (AMHs). Evidence for the coexistence of these two hominins, however, is elusive and, therefore, verifying the role which these processes might have played in the extirpation of Neandertals remains a topic of heated debate. A site which can contribute to throw light on the replacement of H. neanderthalensis by AMHs is Riparo Mezzena, a rockshelter in northern Italy, where late Mousterian lithic industries were found in association with human remains. This paper reviews the results of recent investigations on the lithic assemblages and human bones recovered during excavation campaigns which took place in 1957 and 1977. The study of the physical anthropology of the skeletal remains, in conjunction with palaeogenetic analyses on mitochondrial and nuclear DNA, have proven that the occupiers of Riparo Mezzena were Neandertals. The first radiocarbon date for the site, obtained on collagen extracted from a bovid from the lowermost part of the stratigraphic sequence (Layer III) and presented here (34,540±655 14C uncal BP), attests that Riparo Mezzena was occupied during the Middle-to-Upper Palaeolithic transition period. The anthropogenic deposits at the site actually accumulated when the nearby site of Grotta di Fumane was occupied by humans who produced Proto-Aurignacian lithic industries. This suggests that Neandertals and AMHs probably co-existed for a short period of time in northern Italy, possibly competing for resources within the confined territory of the Monti Lessini. These findings arising from new research on the collections of Riparo Mezzena have important implications not only for the study of the Middle-to-Upper Palaeolithic transition in Italy, but also for the understanding of the process through which AMHs replaced H. neanderthalensis

Climate-driven environmental changes around 8,200 years ago favoured increases in cetacean strandings and Mediterranean hunter-gatherers exploited them

Cetacean mass strandings occur regularly worldwide, yet the compounded effects of natural and anthropogenic factors often complicate our understanding of these phenomena. Evidence of past stranding episodes may, thus, be essential to establish the potential influence of climate change. Investigations on bones from the site of Grotta dell" Uzzo in North West Sicily (Italy) show that the rapid climate change around 8,200 years ago coincided with increased strandings in the Mediterranean Sea. Stable isotope analyses on collagen from a large sample of remains recovered at this cave indicate that Mesolithic hunter-gatherers relied little on marine resources. A human and a red fox dating to the 8.2-kyr-BP climatic event, however, acquired at least one third of their protein from cetaceans. Numerous carcasses should have been available annually, for at least a decade, to obtain these proportions of meat. Our findings imply that climate-driven environmental changes, caused by global warming, may represent a serious threat to cetaceans in the near future

The late Pleistocene to Holocene palaeogeographic evolution of the Porto Conte area: Clues for a better understanding of human colonization of Sardinia and faunal dynamics during the last 30 ka

The timing of the colonization of Sardinia by mammalian fauna and anatomically modern humans (AMH) is currently under debate. The understanding of the geological and palaeoclimatological conditions that characterized the Late Pleistocene and the Holocene is essential to investigate colonization processes and requires an integrated multidisciplinary approach. In this research we combine for the first time new radiometric dating, field evidence of relative sea-level changes (RSL), sea-level and glacial-isostatic adjustment modelling, stratigraphical, palaeontological, palaeoecological and isotope analyses that were performed on sites and finds from the Porto Conte and Capo Caccia area (Alghero, NW Sardinia). The most important Late Pleistocene fossiliferous deposits in Sardinia have been discovered in this part of the island. Modelled palaeogeographical reconstructions of the Porto Conte area combined with the inferred environmental context and chronology of Late Pleistocene faunal assemblages from Medusa-Dragonara Cave suggest that Homo sapiens did not inhabit this area before the Holocene. Our results support the hypothesis that human presence in Sardinia during the Last Glacial Maximum was at best sporadic

Metodologie per la ricostruzione dell’alimentazione nel Paleolitico. Il caso studio di Grotta Paglicci (Rignano Garganico-FG)

International audienc