1,580 research outputs found

    The early medieval origin of Perth, Scotland

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    The radiocarbon results (and Bayesian modeling) of 15 samples of carbonized food residues removed from the external surface of rim sherds of cooking pots indicate that shellyware pottery first appeared in Perth, Scotland, around cal AD 9101020 (95% probability) and that it had disappeared by cal AD 10201140 (95% probability). Previously, it had been suggested that this pottery could not date to before AD 1150. These data, together with 14C analyses carried out on leather artifacts and a sample of wattle from a ditch lining, also demonstrate that there was occupation in Perth about 100 yr or more prior to the granting of royal burgh status to Perth in the 1120s

    Development of the ASQoL: a quality of life instrument specific to ankylosing spondylitis

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    Background: Although disease-specific health status measures are available for ankylosing spondylitis (AS), no instrument exists for assessing quality of life (QoL) in the condition. Objective: To produce an AS-specific QoL measure that would be relevant and acceptable to respondents, valid, and reliable. Methods: The ASQoL employs the needs-based model of QoL and was developed in parallel in the UK and the Netherlands (NL). Content was derived from interviews with patients in each country. Face and content validity were assessed through patient field test interviews (UK and NL). A postal survey in the UK produced a more efficient version of the ASQoL, which was tested for scaling properties, reliability, internal consistency, and validity in a further postal survey in each country. Results: A 41 item questionnaire was derived from interview transcripts. Field testing interviews confirmed acceptability. Rasch analysis of data from the first survey (n=121) produced a 26 item questionnaire. Rasch analysis of data from the second survey (UK: n=164; NL: n=154) showed some item misfit, but showed that items formed a hierarchical order and were stable over time. Problematic items were removed giving an 18 item scale. Both language versions had excellent internal consistency (α=0.89–0.91), test-retest reliability (r(s)=0.92 UK and r(s)=0.91 NL), and validity. Conclusions: The ASQoL provides a valuable tool for assessing the impact of interventions for AS and for evaluating models of service delivery. It is well accepted by patients, taking about four minutes to complete, and has excellent scaling and psychometric properties

    Ranking Templates for Linear Loops

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    We present a new method for the constraint-based synthesis of termination arguments for linear loop programs based on linear ranking templates. Linear ranking templates are parametrized, well-founded relations such that an assignment to the parameters gives rise to a ranking function. This approach generalizes existing methods and enables us to use templates for many different ranking functions with affine-linear components. We discuss templates for multiphase, piecewise, and lexicographic ranking functions. Because these ranking templates require both strict and non-strict inequalities, we use Motzkin's Transposition Theorem instead of Farkas Lemma to transform the generated \exists\forall-constraint into an \exists-constraint.Comment: TACAS 201

    End of Life Care and Do Not Resuscitate Orders: How Much Does Age Influence Decision Making? A Systematic Review and Meta-analysis

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    With population aging, “do not resuscitate” (DNAR) decisions, pertaining to the appropriateness of attempting resuscitation following a cardiac arrest, are becoming commoner. It is unclear from the literature whether using age to make these decisions represents “ageism.” We undertook a systematic review of the literature using CINAHL, Medline, and the Cochrane database to investigate the relationship between age and DNAR. All 10 studies fulfilling our inclusion criteria found that “do not attempt resuscitation” orders were more prevalent in older patients; eight demonstrated that this was independent of other mediating factors such as illness severity and likely outcome. In studies comparing age groups, the adjusted odds of having a DNAR order were greater in patients aged 75 to 84 and ≥85 years (adjusted odds ratio [AOR] 1.70, 95% confidence interval [CI] = [1.25, 2.33] and 2.96, 95% CI = [2.34, 3.74], respectively), compared with those <65 years. In studies treating age as a continuous variable, there was no significant increase in the use of DNAR with age (AOR 0.98, 95% CI = [0.84, 1.15]). In conclusion, age increases the use of “do not resuscitate” orders, but more research is needed to determine whether this represents “ageism.

    A higher order control volume based finite element method to prodict the deformation of heterogeneous materials

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    Materials with obvious internal structure can exhibit behaviour, under loading, that cannot be described by classical elasticity. It is therefore important to develop computational tools incorporating appropriate constitutive theories that can capture their unconventional behaviour. One such theory is micropolar elasticity. This paper presents a linear strain control volume finite element formulation incorporating micropolar elasticity. Verification results from a micropolar element patch test as well as convergence results for a stress concentration problem are included. The element will be shown to pass the patch test and also exhibit accuracy that is at least equivalent to its finite element counterpart

    A Proposed Master of Social Work Based in Indigenous Knowledges Program in Manitoba

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    This article focuses on an innovative proposed Master of Social Work based in Indigenous Knowledges program developed by an Indigenous Caucus within the Faculty of Social Work at the University of Manitoba in Canada. This culturally based program intends to ground students with a solid foundation in traditional Indigenous teachings and perspectives, and contemporary Indigenous philosophies, knowledges, concepts, critiques, and ways of being that stem from these traditions. The proposed Master of Social Work based in Indigenous Knowledges was developed as a lived program that builds community and social supports, and reclaims and re-energizes a sense of self, responsibility, self-sufficiency, self-determination, and self-government. The program’s aim is to deconstruct oppressive and colonialist structures and reconstruct, in a contemporary sense, what has been previously destroyed. An overview of the visions, objectives, program design, foundational themes and description of courses is provided, along with reflections on what teachings its development has provided

    Effect of New Zealand Blackcurrant Extract on Cycling Performance and Substrate Oxidation in Normobaric Hypoxia in Trained Cyclists

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    This study explored New Zealand blackcurrant (NZBC) extract for enhanced exercise-induced fat oxidation and 16.1 km cycling time trial (TT) performance in normobaric normoxia. The effect of NZBC extract on physiological and metabolic responses was examined during steady state cycling and a 16.1 km TT in normobaric hypoxia. This study used a randomized, double-blind, crossover design. Eleven healthy male cyclists (age: 38 ± 11 y, height: 179 ± 4 cm, body mass: 76 ± 8 kg, V ˙ O2max: 47 ± 5 mL·kg−1·min−1, mean ± SD) ingested NZBC extract (600 mg·day−1 CurraNZ® containing 210 mg anthocyanins) or a placebo (600 mg microcrystalline cellulose M102) for seven days (washout 14 days) and performed a steady state cycling test (3 × 10 min at 45%, 55% and 65% V ˙ O2max) followed by a 16.1 km TT at a simulated altitude of ~2500 meters (~15% of O2). Indirect calorimetry was used to measure substrate oxidation during steady state cycling. Intake of NZBC extract had no effect on blood glucose and lactate, heart rate, substrate oxidation, and respiratory exchange ratio during steady state cycling at 45%, 55% and 65% V ˙ O2max, and on 16.1 km TT performance (placebo: 1685 ± 92 s, NZBC extract: 1685 ± 99 s, P = 0.97). Seven days intake of New Zealand blackcurrant extract does not change exercise-induced metabolic responses and 16.1 km cycling time trial performance for moderately endurance-trained men in normobaric hypoxia

    Directed polymers in high dimensions

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    We study directed polymers subject to a quenched random potential in d transversal dimensions. This system is closely related to the Kardar-Parisi-Zhang equation of nonlinear stochastic growth. By a careful analysis of the perturbation theory we show that physical quantities develop singular behavior for d to 4. For example, the universal finite size amplitude of the free energy at the roughening transition is proportional to (4-d)^(1/2). This shows that the dimension d=4 plays a special role for this system and points towards d=4 as the upper critical dimension of the Kardar-Parisi-Zhang problem.Comment: 37 pages REVTEX including 4 PostScript figure

    Energy Norms and the Stability of the Einstein Evolution Equations

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    The Einstein evolution equations may be written in a variety of equivalent analytical forms, but numerical solutions of these different formulations display a wide range of growth rates for constraint violations. For symmetric hyperbolic formulations of the equations, an exact expression for the growth rate is derived using an energy norm. This expression agrees with the growth rate determined by numerical solution of the equations. An approximate method for estimating the growth rate is also derived. This estimate can be evaluated algebraically from the initial data, and is shown to exhibit qualitatively the same dependence as the numerically-determined rate on the parameters that specify the formulation of the equations. This simple rate estimate therefore provides a useful tool for finding the most well-behaved forms of the evolution equations.Comment: Corrected typos; to appear in Physical Review

    Slowly Rotating General Relativistic Superfluid Neutron Stars with Relativistic Entrainment

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    Neutron stars that are cold enough should have two or more superfluids/supercondutors in their inner crusts and cores. The implication of superfluidity/superconductivity for equilibrium and dynamical neutron star states is that each individual particle species that forms a condensate must have its own, independent number density current and equation of motion that determines that current. An important consequence of the quasiparticle nature of each condensate is the so-called entrainment effect, i.e. the momentum of a condensate is a linear combination of its own current and those of the other condensates. We present here the first fully relativistic modelling of slowly rotating superfluid neutron stars with entrainment that is accurate to the second-order in the rotation rates. The stars consist of superfluid neutrons, superconducting protons, and a highly degenerate, relativistic gas of electrons. We use a relativistic σ\sigma - ω\omega mean field model for the equation of state of the matter and the entrainment. We determine the effect of a relative rotation between the neutrons and protons on a star's total mass, shape, and Kepler, mass-shedding limit.Comment: 30 pages, 10 figures, uses ReVTeX
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