Effect of zinc intake on growth in infants: A meta-analysis

A systematic review and meta-analysis of available randomized controlled trials (RCTs) was conducted to evaluate the effect of zinc (Zn) intake on growth in infants. Out of 5500 studies identified through electronic searches and reference lists, 19 RCTs were selected after applying the exclusion/inclusion criteria. The influence of Zn intake on growth was considered in the overall meta-analysis. Other variables were also taken into account as possible effect modifiers: doses of Zn intake, intervention duration, nutritional status, and risk of bias. From each select growth study, final measures of weight, length, mid upper arm circumference (MUAC), head circumference, weight for age z-score (WAZ), length for age z-score (LAZ), and weight for length z-score (WLZ) were assessed. Pooled β and 95% confidence interval (CI) were calculated. Additionally, we carried out a sensitivity analysis. Zn intake was not associated with weight, length, MUAC, head circumference, and LAZ in the pooled analyses. However, Zn intake had a positive and statistically effect on WAZ (β = 0.06; 95%CI 0.02 to 0.10) and WLZ (β = 0.05; 95%CI 0.01 to 0.08). The dose–response relationship between Zn intake and these parameters indicated that a doubling of Zn intake increased WAZ and WLZ by approximately 4%. Substantial heterogeneity was present only in length analyses (I2 = 45%; p = 0.03). Zn intake was positively associated with length values at short time (four to 20 weeks) (β = 0.01; CI 95% 0 to 0.02) and at medium doses of Zn (4.1 to 8 mg/day) (β = 0.003; CI 95% 0 to 0.01). Nevertheless, the effect magnitude was small. Our results indicate that Zn intake increases growth parameters of infants. Nonetheless, interpretation of these results should be carefully considered

The Art of Nurse Mentoring: A Framework of Support

Introduction: Nursing mentoring relationships are vital to the advancement of personal and professional growth in nursing. Mentoring has been identified as an effective method to decrease turnover resulting in retention of experienced nurses. Despite the benefits of a mentoring relationship, barriers exist in creating and cultivating a formal mentoring program in the hospital setting. Methods: A qualitative descriptive study approach that explored nurses’ perceptions of a mentoring culture within a hospital environment. Open-ended, conversational-style interviewing techniques with a semi-structured interview guide were utilized to gain a full description of nurses’ perceptions of a mentoring culture within a hospital environment. Results: A structural model of mentoring as perceived by hospital nurses was developed from the data. Five overarching themes with corresponding subthemes emerged from nurses’ perceptions. (1) Mentoring culture: various mentoring models, informal vs formal, leader focused, and evolving. (2) Benefits: connections, development, retention, stability, patient safety, and making a difference. (3) Barriers: time, patients/patience, competition, knowledge deficit regarding mentor verses preceptor roles, lack of incentives, receptiveness, and voluntold. (4) Experience with mentoring: going above and beyond, lifetime relationships, personal/professional growth, feeling cared for. (5) Paradigm shift: match generational and cultural differences, resources, face-to-face, and voluntary. Discussion: The study results have identified mentoring as an integral aspect of personal and professional growth within the hospital environment. The rewards of mentoring or being mentored can be translated into increased nursing retention and improved nursing job satisfaction

Discriminating the short-term action of root and foliar application of humic acids on plant growth: emerging role of jasmonic acid

Humic substances (HS, fulvic and humic acids) are widely used as fertilizers or plant growth stimulants, although their mechanism of action still remains partially unknown. Humic substances may be applied either directly to the soil or as foliar sprays. Despite both kind of application are commonly used in agricultural practices, most of the studies regarding the elicited response in plants induced by HS are based on the root-application of these substances. The present work aimed at discriminating between the mechanisms of action of foliar application versus root application of a sedimentary humic acid (SHA) on plant development. For this purpose, six markers related to plant phenotype, plant morphology, hormonal balance and root-plasma membrane H+-ATPase were selected. Both application strategies improved the shoot and root growth. Foliar applied- and root applied-SHA shared the capacity to increase the concentration of indole-3-acetic acid in roots and cytokinins in shoots. However, foliar application did not lead to short-term increases in either abscisic acid root-concentration or root-plasma membrane H+-ATPase activity which are, however, two crucial effects triggered by SHA root-application. Both application modes increased the root concentrations of jasmonic acid and jasmonoyl-isoleucine. These hormonal changes caused by foliar application could be a stress-related symptom and connected to the loss of leaves trichomes and the diminution of chloroplasts size seen by scanning electron microscopy. These results support the hypothesis that the beneficial effects of SHA applied to roots or leaves may result from plant adaptation to a mild transient stress caused by SHA application

Insights on biodiversity drivers to predict species richness in tropical forests at the local scale

Disentangling the relative importance of different biodiversity drivers (i.e., climate, edaphic, historical factors, or human impact) to predict plant species richness at the local scale is one of the most important challenges in ecology. Biodiversity modelling is a key tool for the integration of these drivers and the predictions generated are essential, for example, for climate change forecast and conservation planning. However, the reliability of biodiversity models at the local scale remains poorly understood, especially in tropical species-rich areas, where they are required. We inventoried all woody plants with stems ≥ 2.5 cm in 397 plots across the Andes-Amazon gradient. We generated and mapped 19 uncorrelated biodiversity drivers at 90 m resolution, grouped into four categories: microclimatic, microtopographic, anthropic, and edaphic. In order to evaluate the importance of the different categories, we grouped biodiversity drivers into four different clusters by categories. For each of the four clusters of biodiversity drivers, we modelled the observed species richness using two statistical techniques (random forest and Bayesian inference) and two modelling procedures (including or excluding a spatial component). All the biodiversity models produced were evaluated by cross-validation. Species richness was accurately predicted by random forest (Spearman correlation up to 0.85 and explained variance up to 67%). The results suggest that precipitation and temperature are important driving forces of species richness in the region. Nonetheless, a spatial component should be considered to properly predict biodiversity. This could reflect macroevolutionary underlying forces not considered here, such as colonization time, dispersal capacities, or speciation rates. However, the proposed biodiversity modelling approach can predict accurately species richness at the local scale and detailed resolution (90 m) in tropical areas, something that previous works had found extremely challenging. The innovative methodology presented here could be employed in other areas with conservation needsWe thank the Consejería de Educacion (Comunidad de Madrid, Spain), National Geographic Society (8047-06, 7754-04), National Science Foundation (DEB#0101775, DEB#0743457, DEB#1557094), Spanish Ministry of Economy and Competitiveness (CGL2016-75414-P), Centro de Estudios de América Latina (Universidad Autonoma de Madrid – Banco Santander), Consejería de Educacion, Cultura y Deportes (Junta de Comunidades de Castilla-La Mancha, SBPLY/21/180501/000241), Spanish Ministry of Economy and Competitiveness (PID2019-106341GB-I00) for funding our research. The full dataset can be requested from the Madidi Project (https://madidiproject.weebly.com/

Optical calibration facility at the Izaña Atmospheric Research Center [Póster]

Póster presentado en: 37th Annual European Meeting on Atmospheric Studies by Optical Methods, celebrado en 2010 en Valladolid.Financial supports from the Spanish MICIIN (ref.CGL2008-05939-CO3-00/CLIandCGL2009-09740) and from the GR-220 Project of the Junta de Castilla y León are gratefully acknowledged

Comparative efficacy between atorvastatin and rosuvastatin in the prevention of cardiovascular disease recurrence

Background: There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin. In order to analyze potential differences in the clinical response to atorvastatin and rosuvastatin in secondary ASCVD prevention, we have analyzed the clinical evolution of those subjects of the Dyslipemia Registry of the Spanish Society of Arteriosclerosis (SEA) who at the time of inclusion in the Registry had already suffered an ASCVD. Methods: This observational, retrospective, multicenter, national study was designed to determine potential differences between the use of atorvastatin and rosuvastatin in the ASCVD recurrence. Three different follow-up start-times were performed: time of inclusion in the registry; time of first event if this occurred after 2005, and time of first event without date restriction. Results: Baseline characteristics were similar between treatment groups. Among atorvastatin or rosuvastatin users, 89 recurrences of ASCVD were recorded (21.9%), of which 85.4% were coronary. At the inclusion of the subject in the registry, 345 participants had not suffered a recurrence yet. These 345 subjects accumulated 1050 person-years in a mean follow-up of 3 years. Event rates were 2.73 (95% CI: 1.63, 4.25) cases/100 person-years and 2.34 (95% CI: 1.17, 4.10) cases/100 person-years in the atorvastatin and rosuvastatin groups, respectively. There were no statistically significant differences between the two groups independently of the follow-up start-time. Conclusions: This study does not find differences between high doses of rosuvastatin and atorvastatin in the recurrence of ASCVD, and supports their use as clinically equivalent in secondary prevention of ASCVD

Laboratorio de calibración óptica del Centro de Investigación Atmosférica de Izaña

Financial supports from the Spanish MICIIN (ref. CGL2008‐05939‐CO3‐00/CLI and CGL 2009‐ 09740) and from the GR‐220 Project of the Junta de Castilla y León are gratefully acknowledged

Comparing neutral (monometallic) and anionic (bimetallic) aluminium complexes in hydroboration catalysis : influences of lithium cooperation and ligand set

Bimetallic lithium aluminates and neutral aluminum counterparts are compared as catalysts in hydroboration reactions with aldehydes, ketones, imines and alkynes. Possessing Li–Al cooperativity, ate catalysts are found to be generally superior. Catalytic activity is also influenced by the ligand set, alkyl and/or amido. Devoid of an Al−H bond, iBu2Al(TMP) operates as a masked hydride reducing benzophenone through a β‐Η transfer process. This catalyst library therefore provides an entry point into the future design of Al catalysts targeting substrate specific transformations

Preliminary characterization of columnar aerosol properties (AOD-AE) at the Saharan Tamanrasset (Algeria) station [Póster]

Póster presentado en: 37th Annual European Meeting on Atmospheric Studies by Optical Methods, celebrado en 2010 en Valladolid.Financial supports from the Spanish MICIIN (ref.CGL2008-05939-CO3-00/CLIandCGL2009-09740) and from the GR-220 Project of the Junta de Castilla y León are gratefully acknowledged

Caracterización preliminar de las propiedades del aerosol en columna (EOA-EA) en la estación sahariana de Tamanrasset (Argelia)

A Cimel sun photometer has been in operation at Tamanrasset station since late 2006. In this study, more than two years of aerosol measurements have been analyzed from October 2006 to January 2009. Two parameters, aerosol optical depth (AOD) and Ångström exponent (AE), have been used for this preliminar characterization. At this station, the mean AOD is 0.25±0.15 and the mean AE is 0.48±0.23. Both time series data show a clear seasonal cycle. A dry-cool season (fall and winter time), characterized by low AOD and high AE values, and a wet-hot season (in spring-summer), with strong and frequent mineral dust storms, giving high AOD and low AE values, are observed at Tamanrasset. Both, AOD and AE values show the behaviour of a station where desert mineral dust is the prevailing aerosol defining the characteristic of the site. However a significant number of episodes with AE values around 1 together with AOD greater than 0.2 have been found, what suggests the presence of pollution derived aerosols.Financial supports from the Spanish MICIIN (ref. CGL2008-05939-CO3-00/CLI and CGL 2009-09740) and from the GR-220 Project of the Junta de Castilla y León are gratefully acknowledged