Static density response of one-dimensional soft bosons across the clustering transition

One-dimensional bosons interacting via a soft-shoulder potential are investigated at zero temperature. The flatness of the potential at short distances introduces a typical length, such that, at relatively high densities and sufficiently strong interactions, clusters are formed, even in the presence of a completely repulsive potential. We evaluate the static density response function of this system across the transition from the liquid to the cluster liquid phases. Such quantity reveals the density modulations induced by a weak periodic external potential, and is maximal at the clustering wavevector. It is known that this response function is proportional to the static structure factor in the classical regime at high temperature, while for this zero-temperature quantum systems, we extract it from the dynamical structure factor evaluated with quantum Monte Carlo methods.Comment: 7 pages, 3 figures. Proceedings of the "Recent Progress in Many-Body Theories" international conference, Pohang, South Korea, 201

Coronary artery disease associated with severe mitral and tricuspid valve regurgitation after left Pneumonectomy: report of a successful hybrid procedure

The literature concerning heart surgery after pneumonectomy is still poor. Moreover, there is still a lack of a standardized approach to such a patient in the decision-making process. Here, we report a case of a patient who had previously had left pneumonectomy for malignancy and who had coronary artery disease and mitral and tricuspid regurgitation treated with a hybrid procedure

A Markov state modeling analysis of sliding dynamics of a 2D model

Non-equilibrium Markov State Modeling (MSM) has recently been proposed by Pellegrini et al. [Phys. Rev. E 94, 053001 (2016)] as a possible route to construct a physical theory of sliding friction from a long steady state atomistic simulation: the approach builds a small set of collective variables, which obey a transition-matrix-based equation of motion, faithfully describing the slow motions of the system. A crucial question is whether this approach can be extended from the original 1D small size demo to larger and more realistic size systems, without an inordinate increase of the number and complexity of the collective variables. Here we present a direct application of the MSM scheme to the sliding of an island made of over 1000 harmonically bound particles over a 2D periodic potential. Based on a totally unprejudiced phase space metric and without requiring any special doctoring, we find that here too the scheme allows extracting a very small number of slow variables, necessary and sufficient to describe the dynamics of island sliding

Single-shot measurement of phase and topological properties of orbital angular momentum radiation through asymmetric lateral coherence

We show a single-shot technique to measure topological and phase properties of radiation carrying orbital angular momentum. The single-shot method is effectively described as the one-dimensional case of a more general two-dimensional approach based on scanning interferometry (asymmetric lateral coherence). The validity of the method has been experimentally verified and the applicability to ultrarelativistic sources of hard x-rays has been discussed. The method is suitable to characterize phase and topological properties of x-ray sources by using simple apertures

Pre-operational short-term forecasts for Mediterranean Sea biogeochemistry

Operational prediction of the marine environment is recognised as a fundamental research issue in Europe. We present a pre-operational implementation of a biogeochem- ical model for the pelagic waters of the Mediterranean Sea, developed within the framework of the MERSEA-IP Euro- pean project. The OPATM-BFM coupled model is the core of a fully automatic system that delivers weekly analyses and forecast maps for the Mediterranean Sea biogeochem- istry. The system has been working in its current configura- tion since April 2007 with successful execution of the fully automatic operational chain in 87% of the cases while in the remaining cases the runs were successfully accomplished af- ter operator intervention. A description of the system devel- oped and also a comparison of the model results with satel- lite data are presented, together with a measure of the model skill evaluated by means of seasonal target diagrams. Future studies will address the implementation of a data assimila- tion scheme for the biogeochemical compartment in order to increase the skill of the model’s performance

Long-term evaluation of infliximab in the treatment of persistently active juvenile idiopathic arthritis refractory to conventional therapy

Objectives: To evaluate, in long-term open label prospective study, infliximab as therapeutic choice for Juvenile Idiopathic Arthritis (JIA) non responsive to conventional therapy. Methods: We enrolled to treat with infliximab 78 JIA patients (66 females, 12 males): the mean age was 20.7±7.1 years (median 20.9, range 5.4-34.9); mean JIA duration was 13.6±7.6 years (median 13.5, range 0.4-31.4). Infliximab, at dose of 3-10 mg/kg/infusion added to weekly subcutaneous Methotrexate or other previous DMARDs, was administered by intravenous infusions at weeks 0, 2, 6 and every 8 weeks thereafter. Chest X-ray, Mantoux's test, electrocardiogram were performed at baseline; laboratory tests and clinical evaluation were performed at each infusion. Response was evaluated according to ACR improvement criteria. Results: Mean treatment period was 21.6 months±18.8 (median 14.7, range 1.4-72.4). Just after first infusion most of patients reported significant improvement in pain, fatigue, morning stiffness. Infliximab is still successfully administered to 23 patients (29.5%); 55 (70.5%) patients suspended because of: inefficacy (7), infusion reactions (17), adverse events (9), disease flare-up after a period of effectiveness on synovitis, pain, and morning stiffness (19), remission (2), lack of compliance to treatment (1). Infusion reactions, like dyspnea, flushing, chills, headache, hypotension, anxiety, throat oedema, were observed in 29 patients (34.5%). Anti-DNA antibodies were present in 7 patients (none developed Systemic Lupus Eritematous). Conclusions: Infliximab showed impressive effectiveness treating refractory JIA, although most of patients had to discontinue treatment because of disease flare-up or adverse events. Infliximab may represent a good therapeutic choice in patients non-responders to Methotrexate