How is Death Hastening Done? A Review of Existing Sanctioned Death Hastening Decision-Making Processes and Practices

Death hastening is a controversial terminal care option that is currently carried out in only four countries and some US states, with Canada posed to allow it on June 6, 2016. This article focuses on how assisted suicide and euthanasia have been managed in the four countries and US states where it has been sanctioned and practiced. A systematic literature review and additional searches were employed to gain information on the methods, recipients, procedures, regulations, outcomes, and other information available on state-sanctioned death hastening. The findings reveal many different possible models and thus considerations required for planning in advance of death hastening actually occurring.  &nbsp

Drug utilization study and adverse drug reactions of oral anti diabetics among type 2 diabetes mellitus patients in tertiary care hospital

Background: The aim was to evaluate the drug utilization pattern of oral antidiabetic drugs in type 2 diabetes mellitus outpatients and monitor adverse drug reactions (ADRs) associated with oral antidiabetic drugs.Methods: A retrospective observational study was carried out by collecting the data of type 2 diabetes mellitus patients visiting outpatient department of noncommunicable disease clinic of a tertiary care hospital for a period of one year. The data of demographic, drug utilization pattern and adverse drug reactions of patients on oral antidiabetic drugs was collected and entered in a proforma.Results: Total number of patients in this study were 39 out of which 21 (53.85%) patients were females and 18 (46.15%) patients were males. Majority of patients were in the age group 51-70 years (66.6%). Metformin was the most commonly prescribed drug 76.9% followed by Glibenclamide 17.9%. About 7.7% of patients who were taking oral antidiabetic drugs later switched over to insulin as their blood glucose levels were not controlled. Out of 18 (46.15%) patients, hypertension (38.5%) was the most common comorbid condition and a concomitant drug was prescribed was amlodipine 25.6%. Among all the adverse drug reactions observed, diarrhoea was the most common adverse drug reaction reported 76.9%.Conclusions: Metformin was the most commonly used oral antidiabetic drug. Diarrhoea was the common adverse drug reaction reported

Study of adverse drug reactions among tuberculosis patients in a tertiary care hospital: a retrospective observational study

Background: The aims of the study was to study adverse drug reactions (ADRs) among tuberculosis (TB) patients in a tertiary care hospital and to determine causality, severity and outcome of ADRs.Methods: A retrospective observational study was conducted in a tertiary care hospital over a period of 6 months. Data was collected from records of TB patients in RNTCP centre of a tertiary care hospital regarding information of patients, drugs used, ADRs. It was evaluated using appropriate scales. Simple descriptive statistics was used for analysis.Results: Out of 37 patients who experienced ADRs, 22 (59.45%) were male and 15 (40.54%) were female. Majority of patients were in the age group of 36 to 45 years (37.83%). 36 (97.3%) patients were diagnosed with pulmonary TB and 1 (2.7%) patient had extra pulmonary TB. Among 37 ADRs gastrointestinal (GI) reactions were most common 11 (29.72%) followed by musculoskeletal 9 (24.32%). Causality assessment showed 19 (51.35%) as probable and 18 (48.65%) ADRs as possible, Severity assessment was 24 (64.8%) reactions were in mild, 10 (27.02%) in moderate and 3 (8.1%) in severe grades. Outcome assessment was 26 (70.3%) patients were recovering from reactions, 9 (24.32%) had recovered and 2 (5.4%) did not recover at the time of reporting.Conclusions: Proper monitoring of ADRs helps in reducing patient’s burden of repeated hospital visits and expense occurring due to admissions. This can be prevented by educating patients about early reporting of ADRs

BRAND AWARENESS AND PECEPTION OF POTENTIAL CLIENTS AT ONE POINT ONE SOLUTIONS LIMITED

Brand awareness and perception play a pivotal role in influencing consumer behaviourandshaping a company's success in the market. By gaining insights into how the brand is perceived,the company can refine its marketing strategies, reinforce its brand positioning, and ultimately enhance overall client satisfaction. The primary purpose of this research is to investigate how potential clients are aware of OnePoint One Solutions and their preferences for engaging with the company. This study delvesinto various aspects of brand awareness and perception, including the first point of contact withthe company, familiarity with the brand, recall of advertisements, and overall satisfaction with the brand

Genome-wide association analysis of milk yield traits in Nordic Red Cattle using imputed whole genome sequence variants

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Quantitative trait loci for fertility traits in Finnish Ayrshire cattle

v2008okBEL/EG

Performance Evaluation of Wastewater Treatment plant, Vidyaranyapuram, Mysuru

Background: The primary goal of sewage water treatment is to eliminate or bring down the number of pollutants in the sewage water. This study was needed to assess the efficacy of a sewage treatment plant in reducing contaminants levels to comply with government environmental standards. The wastewater re-use for irrigation approaches must be in compliance with the guidelines and indicators must be tracked and impended consistently, it is therefore essential to give top priority to requirements at the stage of evaluating and development to protect land and water supplies as well as public health. Methods: Chemical and biological approaches were used to regulate the removal efficiency of treatment plants. The performance and effectualness of the Vidyaranyapuram sewage treatment plant (STP) in Mysore are evaluated and analyzed in this report. Novelty: Water quality needs to be regularly checked in wastewater treatment facilities. The current study will aid the treatment facility in its efforts to enhance the process of treatment. One would be able to update the effluent efficiency levels depending on the seasonal variations in wastewater treatment as the assessment explains the number of water quality metrics in waste water plants. The obtained analysis results are very helpful in locating, fixing, and maintaining plant operating and maintenance issues, which may be helpful for next plant expansion to be carried out to get good results. Result: The STP\u27s treatment efficiencies were discovered to have a good treatment level in BOD (96%) and a moderate treatment quality in COD (79%) and TSS (75%) removal efficiency during the year 2018. Conclusion: To ensure correct operation and maintenance, trained and experienced workers must analyze treatment performance at predetermined time intervals. The result explains the quality of effluent water and performance of treatment plant. STPs should be used to their full potential to manage the quality of final effluent, and raw sewage sources should be identified

Quantitative trait loci for fertility traits in Finnish Ayrshire cattle

A whole genome scan was carried out to detect quantitative trait loci (QTL) for fertility traits in Finnish Ayrshire cattle. The mapping population consisted of 12 bulls and 493 sons. Estimated breeding values for days open, fertility treatments, maternal calf mortality and paternal non-return rate were used as phenotypic data. In a granddaughter design, 171 markers were typed on all 29 bovine autosomes. Associations between markers and traits were analysed by multiple marker regression. Multi-trait analyses were carried out with a variance component based approach for the chromosomes and trait combinations, which were observed significant in the regression method. Twenty-two chromosome-wise significant QTL were detected. Several of the detected QTL areas were overlapping with milk production QTL previously identified in the same population. Multi-trait QTL analyses were carried out to test if these effects were due to a pleiotropic QTL affecting fertility and milk yield traits or to linked QTL causing the effects. This distinction could only be made with confidence on BTA1 where a QTL affecting milk yield is linked to a pleiotropic QTL affecting days open and fertility treatments

Phytochemical screening and antimicrobial activity of shade dried and sun-dried Aerva lanata (L.) juss. ex schult.

578-584Aerva lanata (L.) Juss. ex Schult. is an important medicinal plant widely used in the treatment of several human ailments in the southern part of India including as a source of Pashana Bheda (Stone Breaker). The plant materials were extracted in different solvent extracts and analyzed to know the composition of minerals, secondary metabolites and the efficacy of solvent extracts against pathogenic bacteria and Candida species. Ethyl acetate extract of sun-dried plant inhibited the growth of S. typhie and K. pneumoniae. The anticandidal activity displayed in ethyl acetate and methanol extracts was very effective against C. glabrata, C. albicans and C. haemulonii respectively. A maximum of 11.834 ppm calcium content was recorded, followed by potassium (6.87 ppm) and magnesium (6.5 ppm). Similarly, amongst the secondary metabolites, saponins (1.987 mg/g) content was maximum, followed by flavonoids (1.85 mg/g) and sterol (0.85 mg/g) in sundried plant material. In shade dried plant material, phenol content was more (1.14 mg/g). No significant difference was observed in the occurrence of secondary metabolites, minerals, and antimicrobial activity between sundried and shade dried plant materials