Response to Dr Herbert Dardik

Farrando Sicilia, Jordi; Lecea, Ignasi de; Fuente Fuente, Carlos; Ribas Seix, Anna; Masana Padrós, Judit; Delgado, José L

Update on Canine Idiopathic Pulmonary Fibrosis in West Highland White Terriers

Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, progressive, interstitial lung disease (ILD) affecting older West Highland white terriers (WHWTs). According to one classification, CIPF is a familial fibrotic ILD in the group of idiopathic interstitial pneumonias. Etiology is unknown but likely arises from interplay between genetic and environmental factors. CIPF shares features with human idiopathic pulmonary fibrosis and human nonspecific interstitial pneumonia. This article describes clinical signs, findings in physical examination, arterial oxygenation, diagnostic imaging, bronchoscopy, bronchoalveolar lavage, histopathology, disease course, and outcome of WHWTs with CIPF; compares canine and human diseases; summarizes biomarker research; and gives an overview of potential treatment.Peer reviewe

Influence of Disorder Strength on Phase Field Models of Interfacial Growth

We study the influence of disorder strength on the interface roughening process in a phase-field model with locally conserved dynamics. We consider two cases where the mobility coefficient multiplying the locally conserved current is either constant throughout the system (the two-sided model) or becomes zero in the phase into which the interface advances (one-sided model). In the limit of weak disorder, both models are completely equivalent and can reproduce the physical process of a fluid diffusively invading a porous media, where super-rough scaling of the interface fluctuations occurs. On the other hand, increasing disorder causes the scaling properties to change to intrinsic anomalous scaling. In the limit of strong disorder this behavior prevails for the one-sided model, whereas for the two-sided case, nucleation of domains in front of the invading front are observed.Comment: Accepted for publication in PR

Interface Equations for Capillary Rise in Random Environment

We consider the influence of quenched noise upon interface dynamics in 2D and 3D capillary rise with rough walls by using phase-field approach, where the local conservation of mass in the bulk is explicitly included. In the 2D case the disorder is assumed to be in the effective mobility coefficient, while in the 3D case we explicitly consider the influence of locally fluctuating geometry along a solid wall using a generalized curvilinear coordinate transformation. To obtain the equations of motion for meniscus and contact lines, we develop a systematic projection formalism which allows inclusion of disorder. Using this formalism, we derive linearized equations of motion for the meniscus and contact line variables, which become local in the Fourier space representation. These dispersion relations contain effective noise that is linearly proportional to the velocity. The deterministic parts of our dispersion relations agree with results obtained from other similar studies in the proper limits. However, the forms of the noise terms derived here are quantitatively different from the other studies

A study of the degree to which satellite- derived gravitational data can be related to the anomalous surface gravity field and other anomalous geophysical parameters Final report

Satellite-derived gravitational data related to anomalous surface gravity field and other geophysical parameters of Solomon Islands are

Thermohydrodynamics of boiling in a van der Waals fluid

We present a modeling approach that enables numerical simulations of a boiling Van der Waals fluid based on the diffuse interface description. A boundary condition is implemented that allows in and out flux of mass at constant external pressure. In addition, a boundary condition for controlled wetting properties of the boiling surface is also proposed. We present isothermal verification cases for each element of our modeling approach. By using these two boundary conditions we are able to numerically access a system that contains the essential physics of the boiling process at microscopic scales. Evolution of bubbles under film boiling and nucleate boiling conditions are observed by varying boiling surface wettability. We observe flow patters around the three-phase contact line where the phase change is greatest. For a hydrophilic boiling surface, a complex flow pattern consistent with vapor recoil theory is observed.Peer reviewe

Many-particle diffusion in continuum: Influence of a periodic surface potential

We study the diffusion of Brownian particles with a short-range repulsion on a surface with a periodic potential through molecular dynamics simulations and theoretical arguments. We concentrate on the behavior of the tracer and collective diffusion coefficients DT(θ) and DC(θ), respectively, as a function of the surface coverage θ. In the high friction regime we find that both coefficients are well approximated by the Langmuir lattice-gas results for up to θ≈0.7 in the limit of a strongly binding surface potential. In particular, the static compressibility factor within DC(θ) is very accurately given by the Langmuir formula for 0⩽θ⩽1. For higher densities, both DT(θ) and DC(θ)show an intermediate maximum which increases with the strength of the potential amplitude. In the low friction regime we find that long jumps enhance blocking and DT(θ) decreases more rapidly for submonolayer coverages. However, for higher densities DT(θ)/DT(0) is almost independent of friction as long jumps are effectively suppressed by frequent interparticle collisions. We also study the role of memory effects for many-particle diffusion.Peer reviewe