Beam Dynamics Studies for the CLIC Main Linac

The implications of long-range wakefields on the beam quality are investigated through a detailed beam dynamics study. Injection offsets are considered and the resulting emittance dilution recorded, including systematic sources of error. These simulations have been conducted for damped and detuned structures (DDS) and for waveguide damped structures-both for the CLIC collider.Comment: 3 pages, 6 figures, IPAC1

The synthesis of optimal controls for linear problems with retarded controls

Synthesis of optimal controls for linear systems with retarded control

Low-energy Selective Laser Trabeculoplasty Repeated Annually: Rationale for the COAST Trial

The recent Laser in Glaucoma and Ocular Hypertension Trial provided the evidentiary basis for a paradigm shift away from the historical medication-first approach to glaucoma--which has numerous limitations, the most important of which is poor adherence to therapy --and toward a laser-first approach. Now 20 years after its commercialization, selective laser trabeculoplasty (SLT) is routinely performed consistently with its initial description, with energy titrated to the appearance of fine, champagne-like cavitation bubbles. A recent data set suggested that lower energy SLT, applied as primary therapy and repeated annually irrespective of intraocular pressure--rather than pro re nata when its effect wanes and irrespective of intraocular pressure rises --yields longer medication-free survival than standard energy SLT repeated pro re nata. A new study--Clarifying the Optimal Application of SLT Therapy --has been initiated to explore this preliminary finding in a pair of consecutive randomized trials. Herein, we provide an evidence-based rationale for the use of low-energy SLT repeated annually as primary therapy for mild to moderate primary open-angle glaucoma or high-risk ocular hypertension

Les négociations

Le projet d’ordonnance portant réforme du droit des contrats entend consacrer la première sous-section, composant la section sur « La conclusion du contrat », aux négociations. Si cet ajout au Code civil est pertinent au regard de la pratique contractuelle et de la jurisprudence, des modifications pourraient toutefois améliorer la cohérence d’ensemble de cette partie

The Relationship between Obstructive Sleep Apnea and Atrial Fibrillation: A Complex Interplay

In recent years, growing evidence suggests an association between obstructive sleep apnea (OSA), a common sleep breathing disorder which is increasing in prevalence as the obesity epidemic surges, and atrial fibrillation (AF), the most common cardiac arrhythmia. AF is a costly public health problem increasing a patient's risk of stroke, heart failure, and all-cause mortality. It remains unclear whether the association is based on mutual risk factors, such as obesity and hypertension, or whether OSA is an independent risk factor and causative in nature. This paper explores the pathophysiology of OSA which may predispose to AF, clinical implications of stroke risk in this cohort who display overlapping disease processes, and targeted treatment strategies such as continuous positive airway pressure and AF ablation

El herbivorismo de Sarpa salpa en los tramos someros de los lechos de Posidonia oceanica

Here, we examined the temporal and small–scale spatial variability of grazing by the herbivorous fish Sarpa salpa on shallow beds of the temperate seagrass Posidonia oceanica. Herbivory intensity expressed as the percent of leaf area taken by fish bites was higher in September 2006 than in February 2007, and at 0.5 m than at 1.5 m during both sampling times. All S. salpa feeding at the shallow locations studied were juveniles, with bite sizes ranging from 0.03 to 0.62 cm2. Juveniles feeding at 1.5 m were larger in February 2007 than in September 2006, as evidenced by significant differences in mean bite size per shoot. However, the larger juveniles feeding at 1.5 m in February 2007 did not appear to feed as frequently as the comparatively smaller juveniles feeding at the same depth in September 2006, as suggested by significant differences in number of bites per shoot. The number of bites per shoot was also lower at 1.5 m than at 0.5 m in February 2007, although mean bite size did not differ significantly between the two depths at that sampling time. In general S. salpa juveniles did not select a particular range of leaf ages when feeding in the study locations, although the juveniles feeding at 1.5 m in September 2006 appeared to select mid–aged leaves. Fish did not show a preference for more epiphytized leaves. These results show that grazing activity by S. salpa juveniles in shallow reaches of P. oceanica meadows may vary temporally and across small changes in depth, which in turn may affect the overall intensity of herbivory on the seagrass.En el presente artículo analizamos la variabilidad temporal y espacial en pequeña escala de la actividad de alimentación del pez herbívoro Sarpa salpa en los lechos someros de la pradera submarina de clima templado Posidonia oceanica. La intensidad del herbivorismo expresada como el porcentaje de superficie foliar mordida por el pez fue superior en septiembre de 2006 que en febrero de 2007, y a una profundidad de 0,5 m que de 1,5 m durante los dos períodos de muestreo. Todos los individuos de S. salpa que se alimentaban en las zonas someras estudiadas eran juveniles y el tamaño de mordedura se situaba entre 0,03 y 0,62 cm2. Los juveniles que se alimentaban a 1,5 m de profundidad fueron más grandes en febrero de 2007 que en septiembre de 2006, tal como ponen de relieve las diferencias significativas existentes en el tamaño medio de mordedura por haz. No obstante, los juveniles más grandes que se alimentaban a 1,5 m de profundidad en febrero de 2007 no parecían alimentarse con tanta frecuencia como los juveniles comparativamente más pequeños, que lo hacían a la misma profundidad en septiembre de 2006, tal como sugieren las diferencias significativas halladas en el número de mordeduras por haz. Asimismo, el número de mordeduras por haz fue inferior a 1,5 m de profundidad que a 0,5 m en febrero de 2007, si bien el tamaño medio de las mordeduras no difería en medida significativa entre las dos profundidades en aquel período de muestreo. En general, los juveniles de S. salpa no elegían un intervalo de edad concreto de las hojas a la hora de alimentarse en los lugares del estudio, a pesar de que los juveniles que se alimentaban a 1,5 m de profundidad en septiembre de 2006 parecían elegir hojas de edad mediana. Los peces no mostraron preferencia por las hojas con mayor cobertura de epífitos. Estos resultados muestran que la actividad de alimentación de los juveniles de S. salpa en los tramos someros de las praderas de P. oceanica puede variar con el tiempo y con pequeños cambios de profundidad, lo que a su vez puede afectar a la intensidad general del herbivorismo sobre las praderas submarinas

Sarpa Salpa Herbivory on Shallow Reaches of Posidonia Oceanica Beds

Sarpa salpa herbivory on shallow reaches of Posidonia oceanica beds.— Here, we examined the temporal and small–scale spatial variability of grazing by the herbivorous fish Sarpa salpa on shallow beds of the temperate seagrass Posidonia oceanica. Herbivory intensity expressed as the percent of leaf area taken by fish bites was higher in September 2006 than in February 2007, and at 0.5 m than at 1.5 m during both sampling times. All S. salpa feeding at the shallow locations studied were juveniles, with bite sizes ranging from 0.03 to 0.62 cm2. Juveniles feeding at 1.5 m were larger in February 2007 than in September 2006, as evidenced by significant differences in mean bite size per shoot. However, the larger juveniles feeding at 1.5 m in February 2007 did not appear to feed as frequently as the comparatively smaller juveniles feeding at the same depth in September 2006, as suggested by significant differences in number of bites per shoot. The number of bites per shoot was also lower at 1.5 m than at 0.5 m in February 2007, although mean bite size did not differ significantly between the two depths at that sampling time. In general S. salpa juveniles did not select a particular range of leaf ages when feeding in the study locations, although the juveniles feeding at 1.5 m in September 2006 appeared to select mid–aged leaves. Fish did not show a preference for more epiphytized leaves. These results show that grazing activity by S. salpa juveniles in shallow reaches of P. oceanica meadows may vary temporally and across small changes in depth, which in turn may affect the overall intensity of herbivory on the seagrass

Realistic simulations of the AGATA Demonstrator+PRISMA spectrometer

Abstract The performance of the AGATA Demonstrator Array coupled to the PRISMA magnetic spectrometer has been evaluated consistently by using detailed Monte Carlo simulations of the two devices. Results for the multi-nucleon transfer reaction 48Ca+208Pb at 310 MeV beam energy are presented and discussed in this study. The present results suggest that the Doppler correction capabilities of the AGATA+PRISMA setup will be very close to the intrinsic energy resolution of the germanium detectors

Comparison of ILC Fast Beam-Beam Feedback Performance in the e−e−e^- e^- and e+e−e^+ e^- Modes of Operation

Several feedback loops are required in the Beam Delivery System (BDS) of the International Linear Collider (ILC) to preserve the luminosity in the presence of dynamic imperfections. Realistic simulations have been carried out to study the performance of the beam-beam deflection based fast feedback system, for both e+e- and e-e- modes of operation. The beam-beam effects in the e-e- collisions make both the luminosity and the deflections more sensitive to offsets at the interaction point (IP) than in the case of the e+e-collisions. This reduces the performance of the feedback system in comparison to the standard e+e- collisions, and may require a different beam parameter optimization