Desarrollo de un Bot Evolutivo Interactivo para Unreal Tournament 2004

En este trabajo se ha implementado un algoritmo genético interactivo en un bot para el juego Unreal Tournament 2004, utilizando como base un bot que se definió anteriormente modelando el conocimiento de un jugador experto. El algoritmo ofrece dos tipos de interacción: por parte de un experto en el juego, o por parte de un experto en el algoritmo. Cada uno influirá en distintos aspectos del algoritmo, para dirigirlo hacia unos mejores resultado con respecto a la humanidad que presente el bot (objetivo de este artículo). Se ha hecho un análisis de la influencia del experto en la ejecución y los resultados muestran cierta mejoría con la versión sin interactividad. El mejor bot obtenido como resultado ha sido presentado a la BotPrize competition de 2014 (buscan el bot más humano posible), quedando en segundo lugar.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Evolutionary Interactive Bot for the FPS Unreal Tournament 2004

This paper presents an interactive genetic algorithm for generating a human-like autonomous player (bot) for the game Unreal Tournament 2004. It is based on a bot modelled from the knowledge of an expert human player. The algorithm provides two types of interaction: by an expert in the game and by an expert in the algorithm. Each one affects different aspects of the evolution, directing it towards better results regarding the agent’s humanness (objective of this work). It has been conducted an analysis of the experts’ influence on the performance, showing much better results after these interactions that the non-interactive version. The best bot were submitted to the BotPrize 2014 competition (which seeks for the best human-like bot), getting the second positionUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Novedades para las aráceas costarricenses (Araceae) con notas nomenclaturales

Background and Aims: Araceae is a worldwide family of herbaceous plants, most notable for its striking morphological diversity and broad habitat diversity. It comprises eight subfamilies, 143 genera, and 3667 species. The Central American region has about 780 species, of which 262 are distributed in Costa Rica. In this contribution, we include four new aroid records for the Costa Rican flora belonging to the genera Anthurium, Philodendron, and Spathiphyllum. In addition, nomenclatural aspects of A. myosuroides are discussed. Methods: The new records resulted from fieldwork on Fila Anguciana, Cerro Turrubares, and Volcán Miravalles. The correct taxonomic identity of the species was confirmed based on literature and comparison with herbarium specimens, especially type specimens from the herbaria of the Universidad de Panama (PMA) and the Missouri Botanical Garden (MO), as well as consultation of the JSTOR Global Plants database and the collections of the Muséum National d'Histoire Naturelle de Paris (P) online. Descriptions, taxonomic discussions, and figures of the morphological characteristics of the new records are provided. Key results: We present Anthurium roseospadix, A. myosuroides, Philodendron pseudauriculatum and Spathiphyllum dressleri as new records for the Costa Rican flora. Moreover, lectotypification for Pothos myosuroides is proposed. Conclusions: Considering the new records presented in this work, the aroid flora of Costa Rica now comprises 266 species, and the total species numbers for Anthurium, Philodendron, and Spathiphyllum increased to 94, 63, and 10, respectively.Antecedentes y Objetivos: Araceae es una familia de plantas herbáceas ampliamente distribuida en el mundo, es notable por su sorprendente diversidad morfológica y su vasta variedad de hábitats. La familia comprende ocho subfamilias, 143 géneros y 3667 especies. La región centroamericana posee alrededor de 780 especies, de las cuales 262 se encuentran en Costa Rica. En esta contribución, incluimos cuatro nuevos registros de aráceas para la flora de Costa Rica, pertenecientes a los géneros Anthurium, Philodendron y Spathiphyllum. Adicionalmente, se discuten aspectos nomenclaturales de A. myosuroides. Métodos: Los nuevos registros se realizaron mediante trabajo de campo en Fila Anguciana, Cerros Turrubares y Volcán Miravalles. La correcta identidad taxonómica de las especies se confirmó mediante la revisión de literatura y por comparación con especímenes de herbario, especialmente los ejemplares tipo provistos por los herbarios de la Universidad de Panamá (PMA) y el Jardín Botánico de Missouri (MO). También se consultó, en línea, la base de datos de JSTOR Global Plants y la colección del Muséum National d’Histoire Naturelle de París (P). Se proporcionan descripciones, discusiones taxonómicas e ilustraciones de las características morfológicas de los nuevos registros. Resultados clave: Se presentan Anthurium roseospadix, A. myosuroides, Philodendron pseudauriculatum y Spathiphyllum dressleri como nuevos registros para la flora de Costa Rica. Además, se propone una lectotipificación para Pothos myosuroides. Conclusiones: Considerando los nuevos registros presentados en este trabajo, la flora de aráceas de Costa Rica ahora comprende 266 especies, donde la diversidad de Anthurium, Philodendron y Spathiphyllum aumentó a 94, 63 y 10 especies, respectivamente

Arterial catheter-related infection of 2,949 catheters

INTRODUCTION: Which particular arterial catheter site is associated with a higher risk of infection remains controversial. The Centers for Disease Control and Prevention guidelines of 1996 and the latest guidelines of 2002 make no recommendation about which site or sites minimize the risk of catheter-related infection. The objective of the present study was to analyze the incidence of catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of arterial catheters according to different access sites. METHODS: We performed a prospective observational study of all consecutive patients admitted to the 24 bed medical and surgical intensive care unit of a 650 bed university hospital during three years (1 May 2000 to 30 April 2003). RESULTS: A total of 2,018 patients was admitted to the intensive care unit during the study period. The number of arterial catheters, the number of days of arterial catheterization, the number of CRLIs and the number of CRBSIs were as follows: total, 2,949, 17,057, 20 and 10; radial, 2,088, 12,007, 9 and 3; brachial, 112, 649, 0 and 0; dorsalis pedis, 131, 754, 0 and 0; and femoral, 618, 3,647, 11 and 7. The CRLI incidence was significantly higher for femoral access (3.02/1,000 catheter-days) than for radial access (0.75/1,000 catheter-days) (odds ratio, 1.5; 95% confidence interval, 1.10–2.13; P = 0.01). The CRBSI incidence was significantly higher for femoral access (1.92/1,000 catheter-days) than for radial access (0.25/1,000 catheter-days) (odds ratio, 1.9; 95% confidence interval, 1.15–3.41; P = 0.009). CONCLUSION: Our results suggest that a femoral site increases the risk of arterial catheter-related infection

Accidental catheter removal in critically ill patients: a prospective and observational study

INTRODUCTION: The importance of accidental catheter removal (ACR) lies in the complications caused by the removal itself and by catheter reinsertion. To the best of our knowledge, no studies have analyzed accidental removal of various types of catheters in the intensive care unit (ICU). The objective of the present study was to analyze the incidence of ACR for all types of catheters in the ICU. METHODS: This was a prospective and observational study, conducted in a 24-bed medical/surgical ICU in a university hospital. We included all consecutive patients admitted to the ICU over 18 months (1 May 2000 to 31 October 2001). The incidences of ACR for all types of catheters (both per 100 catheters and per 100 catheter-days) were determined. RESULTS: A total of 988 patients were included. There were no significant differences in ACR incidence between the four central venous access sites (peripheral, jugular, subclavian and femoral) or between the four arterial access sites (radial, femoral, pedal and humeral). However, the incidence of ACR was higher for arterial than for central venous catheters (1.12/100 catheter-days versus 2.02/100 catheter-days; P < 0.001). The incidences of ACR/100 nonvascular catheter-days were as follows: endotracheal tube 0.79; nasogastric tube 4.48; urinary catheter 0.32; thoracic drain 0.56; abdominal drain 0.67; and intraventricular brain drain 0.66. CONCLUSION: We found ACR incidences for central venous catheter, arterial catheter, endotracheal tube, nasogastric tube and urinary catheter that are similar to those reported in previous studies. We could not find studies that analyzed the ACR for thoracic, abdominal, intraventricular brain and cardiac surgical drains, but we believe that our rates are acceptable. To minimize ACR, it is necessary to monitor its incidence carefully and to implement preventive measures. In our view, according to establish quality standards, findings should be reported as ACR incidence per 100 catheters and per 100 catheter-days, for all types of catheters

Software architecture for customized physical exercise prescription

En la actualidad existe una gran cantidad de aplicaciones para la realización de ejercicio físico. En este artículo se presenta una arquitectura software para una aplicación que permite la prescripción de ejercicios físicos personalizados. Esta arquitectura incluye dos funcionalidades, la funcionalidad para el especialista que prescribe el ejercicio y la funcionalidad para el usuario que debe seguir esta prescripción. La interacción entre el especialista y el usuario se realiza mediante el envío de eventos. Especialistas (médicos/fisioterapeutas/educadores físicos) pueden indicar los ejercicios adecuados en cada caso. Esta aplicación permitirá a los usuarios con demanda de atención personalizada mejorar la condición física y la calidad de vida. Los usuarios podrán realizar el ejercicio físico de forma autónoma, sin tener que realizar desplazamientos y en un horario flexibleCurrently there is a lot of available applications to do physical exercise. This article describes the software architecture for an application that allows customized exercise prescription. This architecture includes two functionalities, the functionality that allows specialists to prescribe physical exercises and the functionality for users who must follow this prescription. Interactions between specialists and users are allowed by means of sending events. Specialists (doctors, physiotherapists and physical educators) can indicate appropriate exercises in each case. This application will allow users with demand for personalized attention to improve their fitness and quality of life. Users can perform physical exercise autonomously, without having to travel and in a flexible schedul

PTL: A Model Transformation Language based on Logic Programming

In this paper we present a model transformation language based on logic programming. The language, called PTL (Prolog based Transformation Language), can be considered as a hybrid language in which ATL (Atlas Transformation Language)-style rules are combined with logic rules for defining transformations. ATL-style rules are used to define mappings from source models to target models while logic rules are used as helpers. The implementation of PTL is based on the encoding of the ATL-style rules by Prolog rules. Thus, PTL makes use of Prolog as a transformation engine. We have provided a declarative semantics to PTL and proved the semantics equivalent to the encoded program. We have studied an encoding of OCL (Object Constraint Language) with Prolog goals in order to map ATL to PTL. Thus a subset of PTL can be considered equivalent to a subset of ATL. The proposed language can be also used for model validation, that is, for checking constraints on models and transformations. We have equipped our language with debugging and tracing capabilities which help developers to detect programming errors in PTL rules. Additionally, we have developed an Eclipse plugin for editing PTL programs, as well as for debugging, tracing and validation. Finally, we have evaluated the language with several transformation examples as well as tested the performance with large models

Evaluación de eventos adversos causados por el uso de Amitriptilina 25 mg tableta, en pacientes de 65 a 70 años para el tratamiento de trastornos depresivos que asisten a consulta externa en el Hospital Psiquiátrico Nacional de Atención Psicosocial “Dr. José Dolores Fletes Valle”. Managua-Nicaragua. Junio-Agosto 2019

La farmacovigilancia es la disciplina que se encarga de dar seguimiento a los riesgos asociados al uso de los medicamentos, el presente estudio pretende realizar un estudio de eventos adversos medicamentosos (EAM) este análisis permite evaluar las afectaciones que ocurren luego de haber suministrado un fármaco a un individuo y la influencia de la atención medica en dicho evento adverso medicamentoso; se buscará información de adultos mayores de 65 a 70 años, que sufren depresión y son tratados con Amitriptilina; la depresión es un trastorno emocional que puede incapacitar al individuo y volverse crónico, por tanto se espera encontrar ¿Cuáles son los eventos adversos causados por el uso de Amitriptilina 25mg tableta, que presentan los pacientes de 65 a 70 años diagnosticados con trastorno depresivo en el Hospital Psiquiátrico Nacional de Atención Psicosocial “Dr. José Dolores Fletes Valle” en el período de Junio - Agosto 2019? Para recolectar la información se utilizó la hoja de recolección de datos y se tabuló en Microsoft Excel 2017 para llevar un mejor control y orden de la información obtenida, de los datos recolectados se obtuvo una mayor incidencia del sexo femenino que padece depresión, a su vez el mayor porcentaje proviene de la ciudad de Managua, el 89% de las dosis cumplían con las dosis recomendadas por el formulario nacional de medicamentos. Se concluye que los eventos adversos medicamentosos son evitables, que son leves y que la opinión de cada paciente debe ser tomada en cuenta, para brindarle el tratamiento idóneo para tratar su patología. Palabras clave: eventos adversos, Amitriptilina, depresión, adultos mayore

Heptagon-Containing Nanographene Embedded into [10]Cycloparaphenylene

We report the synthesis and characterization of a novel type of nanohoop, consisting of a cycloparaphenylene derivative incorporating a curved heptagon-containing π-extended polycyclic aromatic hydrocarbon (PAH) unit. We demonstrate that this new macrocycle behaves as a supramolecular receptor of curved π-systems such as fullerenes C60 and C70, with remarkably large binding constants (ca. 107 M−1), as estimated by fluorescence measurements. Nanosecond and femtosecond spectroscopic analysis show that these host-guest complexes are capable of quasi-instantaneous charge separation upon photoexcitation, due to the ultrafast charge transfer from the macrocycle to the complexed fullerene. These results demonstrate saddle-shaped PAHs with dibenzocycloheptatrienone motifs as structural components for new macrocycles displaying molecular receptor abilities and versatile photochemical responses with promising electron-donor properties in host-guest complexes.Junta de Andalucia-Consejeria de Universidad, Investigacion e Innovacion and FEDER(ERDF) "A way of making Europe" P18-FR-2877ERDF "A way of making Europe"Universidad de Granada / CBU