658 research outputs found

    Search Bias Quantification: Investigating Political Bias in Social Media and Web Search

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    Users frequently use search systems on the Web as well as online social media to learn about ongoing events and public opinion on personalities. Prior studies have shown that the top-ranked results returned by these search engines can shape user opinion about the topic (e.g., event or person) being searched. In case of polarizing topics like politics, where multiple competing perspectives exist, the political bias in the top search results can play a significant role in shaping public opinion towards (or away from) certain perspectives. Given the considerable impact that search bias can have on the user, we propose a generalizable search bias quantification framework that not only measures the political bias in ranked list output by the search system but also decouples the bias introduced by the different sources—input data and ranking system. We apply our framework to study the political bias in searches related to 2016 US Presidential primaries in Twitter social media search and find that both input data and ranking system matter in determining the final search output bias seen by the users. And finally, we use the framework to compare the relative bias for two popular search systems—Twitter social media search and Google web search—for queries related to politicians and political events. We end by discussing some potential solutions to signal the bias in the search results to make the users more aware of them.publishe

    Global dynamics in the Poincare ball of the Chen system having invariant algebraic surfaces

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    Agraïments: The second author is supported by CNPq-Brazil under the project 305204/2009-2. The third author is partially supported by CNPq and FAPESP. All the authors are supported by the Int. Coop. Proj. CAPES/MECD-TQED II and PHB-2009-0025

    Modeling Coordinated vs. P2P Mining: An Analysis of Inefficiency and Inequality in Proof-of-Work Blockchains

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    We study efficiency in a proof-of-work blockchain with non-zero latencies, focusing in particular on the (inequality in) individual miners' efficiencies. Prior work attributed differences in miners' efficiencies mostly to attacks, but we pursue a different question: Can inequality in miners' efficiencies be explained by delays, even when all miners are honest? Traditionally, such efficiency-related questions were tackled only at the level of the overall system, and in a peer-to-peer (P2P) setting where miners directly connect to one another. Despite it being common today for miners to pool compute capacities in a mining pool managed by a centralized coordinator, efficiency in such a coordinated setting has barely been studied. In this paper, we propose a simple model of a proof-of-work blockchain with latencies for both the P2P and the coordinated settings. We derive a closed-form expression for the efficiency in the coordinated setting with an arbitrary number of miners and arbitrary latencies, both for the overall system and for each individual miner. We leverage this result to show that inequalities arise from variability in the delays, but that if all miners are equidistant from the coordinator, they have equal efficiency irrespective of their compute capacities. We then prove that, under a natural consistency condition, the overall system efficiency in the P2P setting is higher than that in the coordinated setting. Finally, we perform a simulation-based study to demonstrate that even in the P2P setting delays between miners introduce inequalities, and that there is a more complex interplay between delays and compute capacities

    Investigating evidence for different black hole accretion modes since redshift z~1

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    Chandra data in the COSMOS, AEGIS-XD and 4Ms CDFS are combined with optical/near-IR photometry to determine the rest-frame U-V vs V-J colours of X-ray AGN hosts at mean redshifts 0.40 and 0.85. This combination of colours (UVJ) provides an efficient means of separating quiescent from star-forming, including dust reddened, galaxies. Morphological information emphasises differences between AGN split by their UVJ colours. AGN in quiescent galaxies are dominated by spheroids, while star-forming hosts are split between bulges and disks. The UVJ diagram of AGN hosts is then used to set limits on the accretion density associated with evolved and star-forming systems. Most of the black hole growth since z~1 is associated with star-forming hosts. Nevertheless, ~15-20% of the X-ray luminosity density since z~1, is taking place in the quiescent region of the UVJ diagram. For the z~0.40 subsample, there is tentative evidence (2sigma significance), that AGN split by their UVJ colours differ in Eddington ratio. AGN in star-forming hosts dominate at high Eddington ratios, while AGN in quiescent hosts become increasingly important as a fraction of the total population toward low Eddington ratios. At higher redshift, z~0.8, such differences are significant at the 2sigma level only at Eddington ratios >1e-3. These findings are consistent with scenarios in which diverse accretion modes are responsible for the build-up of SMBHs at the centres of galaxies. We compare our results with the GALFORM semi-analytic model, which postulates two black hole fuelling modes, the first linked to star-formation and the second occuring in passive galaxies. GALFORM predicts a larger fraction of black hole growth in quiescent galaxies at z<1, compared to the data. Relaxing the strong assumption of the model that passive AGN hosts have zero star-formation rate could reconcile this disagreement.Comment: MNRAS accepte

    MPO-ANCA-Associated Necrotizing Glomerulonephritis in Rheumatoid Arthritis; a Case Report and Review of Literature

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    BACKGROUND: Renal involvement in rheumatoid arthritis (RA) is common and has a negative impact on patient survival. Only few cases have been reported of necrotizing glomerulonephritis (GN) associated with myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) in patients with RA. CASE PRESENTATION: We report a patient with RA who developed a necrotizing GN associated with ANCA-MPO, treated with rituximab (RTX). A 55-year-old man with a 27-year history of RA under secukinumab was referred to our nephrology clinic with worsening renal function associated with microhematuria and proteinuria. Our laboratory evaluation showed hypocomplementemia and positive titers for MPO-ANCA (615 U/mL). A renal biopsy demonstrated pauci-immune necrotizing GN. The patient was treated with 3 consecutive pulses of methylprednisolone followed by oral prednisolone (1 mg/Kg) and rituximab (1000 mg, repeated 14 days later). After a 10-month follow-up, the arthritis remains well-controlled, renal function stabilized, proteinuria improved and MPO-ANCA titer normalized (6.3 U/mL). CONCLUSIONS: Necrotizing GN is a rare but a serious condition and an early diagnosis is essential to treatment. This is the first case of necrotizing GN (without extra-renal manifestations of vasculitis) in a patient with active RA, successfully treated with RTX.info:eu-repo/semantics/publishedVersio

    Optical, near-IR and sub-mm IFU Observations of the nearby dual AGN Mrk 463

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    We present optical and near-IR Integral Field Unit (IFU) and ALMA band 6 observations of the nearby dual Active Galactic Nuclei (AGN) Mrk 463. At a distance of 210 Mpc, and a nuclear separation of ∼\sim4 kpc, Mrk 463 is an excellent laboratory to study the gas dynamics, star formation processes and supermassive black hole (SMBH) accretion in a late-stage gas-rich major galaxy merger. The IFU observations reveal a complex morphology, including tidal tails, star-forming clumps, and emission line regions. The optical data, which map the full extent of the merger, show evidence for a biconical outflow and material outflowing at >>600 km s−1^{-1}, both associated with the Mrk 463E nucleus, together with large scale gradients likely related to the ongoing galaxy merger. We further find an emission line region ∼\sim11 kpc south of Mrk 463E that is consistent with being photoionized by an AGN. Compared to the current AGN luminosity, the energy budget of the cloud implies a luminosity drop in Mrk 463E by a factor 3-20 over the last 40,000 years. The ALMA observations of 12^{12}CO(2-1) and adjacent 1mm continuum reveal the presence of ∼\sim109^{9}M⊙_\odot in molecular gas in the system. The molecular gas shows velocity gradients of ∼\sim800 km/s and ∼\sim400 km/s around the Mrk 463E and 463W nuclei, respectively. We conclude that in this system the infall of ∼\sim100s M⊙M_\odot/yr of molecular gas is in rough balance with the removal of ionized gas by a biconical outflow being fueled by a relatively small, <<0.01% of accretion onto each SMBH.Comment: Accepted by The Astrophysical Journal, 23 pages, 19 figure

    A protocol for large scale genomic DNA isolation for cacao genetics analysis

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    Advances in DNA technology, such as marker assisted selection, detection of quantitative trait loci and genomic selection also require the isolation of DNA from a large number of samples and the preservation of tissue samples for future use in cacao genome studies. The present study proposes a method for the preservation of sample tissues for DNA extraction and for manual extraction of large number of samples using spheres. The integrity and concentration of the DNA by these methods were assessed and compared with conventional method using mortar. The best parameters in order to obtain a fine powder using spheres was the use of 4 lyophilized leaf disks (50 mg), a single steel ball of 6 mm in diameter, followed by 30 s of manual maceration. The quantity of DNA obtained was four times higher than the conventional method. The purity of the DNA obtained was satisfactory and proved to be amplifiable by PCR using SSR primers. The present approach is a reliable, rapid, simple and consistent DNA isolation method for cacao, compared to the conventional methods. The protocol greatly increases the efficiency of extraction and suggests an inexpensive and practical way of DNA isolation of cacao for large scale.Keywords: DNA extraction, cacao, spheres, lyophilized
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