216 research outputs found
Mood And Decision-Making
The purpose of this diary study with a three-month follow up among 67 business starters was to test the influence of positive and negative mood on self-reported decision effectiveness and goal attainment. Intrinsic motivation and scope of attention were included as possible mediating variables. Results of mixed linear model analyses showed a strong positive relationship between mood and motivation at the time of decision making. However, no relationship between motivation and decision effectiveness or goal attainment was found. Only negative mood, and not positive mood, related to entrepreneurs’ scope of attention. As predicted, negative mood narrowed the scope of attention. However, a broad scope of attention during decision-making negatively influenced decision effectiveness and goal attainment as assessed three months later, on top of a concurrent positive relationship between positive mood and self-reported decision effectiveness and goal attainment at the time of follow-up
Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology
Four recombinant, diagnostically useful Epstein-Barr virus (EBV) proteins representative of the viral capsid antigen (p150), diffuse early antigen (p54), the major DNA-binding protein (p138), and the EBV nuclear antigen (p72) (W. Hinderer, H. Nebel-Schickel, H.H. Sonneborn, M. Motz, R. Kühbeck, and H. Wolf, J. Exp. Clin. Cancer Res. 7[Suppl.]:132, 1988) were used to set up individual enzyme-linked immunosorbent assays (ELISAs) for the qualitative and quantitative detection of immunoglobulin M (IgM) and IgG antibodies. In direct comparison with results obtained by standard immunofluorescence or immunoperoxidase assays, it was then shown that the recombinant EBV ELISAs provide the means for specific and sensitive serodiagnosis of infectious mononucleosis (IM) caused by EBV. The most useful markers in sera from such patients proved to be IgM antibodies against p54, p138, and p150. Additional positive markers for recent or ongoing IM apparently were IgG antibodies against p54 and p138. In contrast, anti-p72 IgG had a high preference for sera from healthy blood donors and, therefore, can be considered indicative of past exposure to the virus. Altogether, the individual ELISAs proved to be as specific and at least as sensitive for the diagnosis of IM as the currently available standard techniques are. Moreover, our findings suggest that, by combining individual test antigens, a workable ELISA system consisting of three assays (IgM against p54, p138, and p150; IgG against p54 and p138; and IgG against p72) can be established for the standardized rapid diagnosis of acute EBV infections
Evaluation of Two Rapid Detection Assays for Identification of Respiratory Syncytial Virus in Nasopharyngeal Secretions of Young Children
Investigation of solidification behavior of the Sn-rich ternary Sn-Bi-Zn alloys
Solidification properties and microstructure of six as-cast Sn-Bi-Zn alloys with 80 at.% of Sn and variable contents of Bi and Zn were experimentally investigated using the scanning electron microscopy (SEM) with energy-dispersive X-ray spectroscopy (EDS) and differential scanning calorimetry (DSC). The experimentally obtained results were compared with predicted phase equilibria according to the calculation of phase diagram (CALPHAD) method and by the Scheil solidification simulation.
Thermal characterization of the In–Sn–Zn eutectic alloy
Thermal properties, including melting temperature, latent heat of melting, specific heat capacity and thermal conductivity, of a low-melting In–Sn–Zn eutectic alloy were investigated in this work. The In–Sn–Zn eutectic alloy with nominal composition 52.7In-44.9Sn-2.4Zn (at.%) was prepared by the melting of pure metals under an argon atmosphere. The conducted assessment consisted of both theoretical and experimental approaches. Differential scanning calorimetry (DSC) was used for the measurement of melting temperature and latent heat, and the obtained results were compared with the results of thermodynamic calculations. The measured melting temperature and the latent heat of melting for the In–Sn–Zn eutectic alloy are 106.5±0.1 °C and 28.3±0.1 Jg-1, respectively. Thermal diffusivity and thermal conductivity of the In–Sn–Zn eutectic alloy were studied by the xenon-flash method. The determined thermal conductivity of the investigated eutectic alloy at 25 °C is 42.2±3.4 Wm-1K-1. Apart from providing insight into the possibility for application of the investigated alloy as the metallic phase-change material, the obtained values of thermal properties can also be utilized as input parameters for various simulation processes such as casting and soldering.Djordje Drobnjak - Memorial Issu
Decreasing Proportion of Recent Infections among Newly Diagnosed HIV-1 Cases in Switzerland, 2008 to 2013 Based on Line-Immunoassay-Based Algorithms.
BACKGROUND: HIV surveillance requires monitoring of new HIV diagnoses and differentiation of incident and older infections. In 2008, Switzerland implemented a system for monitoring incident HIV infections based on the results of a line immunoassay (Inno-Lia) mandatorily conducted for HIV confirmation and type differentiation (HIV-1, HIV-2) of all newly diagnosed patients. Based on this system, we assessed the proportion of incident HIV infection among newly diagnosed cases in Switzerland during 2008-2013.
METHODS AND RESULTS: Inno-Lia antibody reaction patterns recorded in anonymous HIV notifications to the federal health authority were classified by 10 published algorithms into incident (up to 12 months) or older infections. Utilizing these data, annual incident infection estimates were obtained in two ways, (i) based on the diagnostic performance of the algorithms and utilizing the relationship 'incident = true incident + false incident', (ii) based on the window-periods of the algorithms and utilizing the relationship 'Prevalence = Incidence x Duration'. From 2008-2013, 3'851 HIV notifications were received. Adult HIV-1 infections amounted to 3'809 cases, and 3'636 of them (95.5%) contained Inno-Lia data. Incident infection totals calculated were similar for the performance- and window-based methods, amounting on average to 1'755 (95% confidence interval, 1588-1923) and 1'790 cases (95% CI, 1679-1900), respectively. More than half of these were among men who had sex with men. Both methods showed a continuous decline of annual incident infections 2008-2013, totaling -59.5% and -50.2%, respectively. The decline of incident infections continued even in 2012, when a 15% increase in HIV notifications had been observed. This increase was entirely due to older infections. Overall declines 2008-2013 were of similar extent among the major transmission groups.
CONCLUSIONS: Inno-Lia based incident HIV-1 infection surveillance proved useful and reliable. It represents a free, additional public health benefit of the use of this relatively costly test for HIV confirmation and type differentiation
Authentic leadership and employees’ innovative behaviour: A multilevel investigation in three countries
The innovativeness of individual employees is a vital source of competitive advantage of firms, contributing to societal development. Therefore, the aim of this multilevel study was to examine how entrepreneurial firm owners’ authentic leadership relates to their employees’ innovative behaviour. Our conceptual model postulates that the relationship between business owners’ authentic leadership (as perceived by their employees) and their employees’ innovative behaviour is mediated by employees’ personal initiative and their work engagement. Hypotheses derived from this model were tested on data collected from 711 employees working in 85 small firms from three European countries: the Netherlands, Poland, and Spain. The results of the multilevel modelling confirmed our model, showing that when business owners are perceived as more authentic leaders, their employees show higher personal initiative and are more engaged at work and, in turn, identify more innovative solutions to be implemented in the organization. A cross-national difference was observed: employees from Spain (in comparison to Dutch and Polish employees) reported engaging less frequently in innovative behaviour. These research findings suggest that the innovative behaviour of employees can be boosted through leadership training, improving the quality of relationships between leaders and subordinates, and strengthening employees’ personal initiative and work engagement
More than money:developing an integrative multi-factorial measure of entrepreneurial success
This article conceptualises and operationalizes ‘subjective entrepreneurial success’ in a manner which reflects the criteria employed by entrepreneurs, rather than those imposed by researchers. Using two studies, a first qualitative enquiry investigated success definitions using interviews with 185 German entrepreneurs; five factors emerged from their reports: firm performance, workplace relationships, personal fulfilment, community impact, and personal financial rewards. The second study developed a questionnaire, the Subjective Entrepreneurial Success–Importance Scale (SES-IS), to measure these five factors using a sample of 184 entrepreneurs. We provide evidence for the validity of the SES-IS, including establishing systematic relationships of SES-IS with objective indicators of firm success, annual income and entrepreneur satisfaction with life and financial situation. We also provide evidence for the cross-cultural invariance of SES-IS using a sample of Polish entrepreneurs. The quintessence of our studies being that subjective entrepreneurial success is a multi-factorial construct, i.e. entrepreneurs value various indicators of success with money as only one possible option
Aseptic meningitis in Germany associated with echovirus type 13
BACKGROUND: Echoviruses are the commonest cause of aseptic meningitis. Echovirus type 13 which has not been isolated in Germany over a long period of time was the predominant enterovirus serotype associated with different local outbreaks of aseptic meningitis in Germany in 2000. METHODS: Virus isolation was performed from cerebrospinal fluid and stools. In order to study the genetic relationship of echovirus type 13 isolates, sequence analysis of a part of VP1 (~300 nt) was carried out. Isolates from different geographic regions were compared to each other as well as to elder viruses (prototype strain from 1953, four isolates from 1965–1986). RESULTS: Overall, 55 isolates of echovirus type 13 were obtained from different parts of Germany. It was shown that the new isolated strains have a very high degree of homology on the nucleotide level (> 98%)) but differ significantly from the old strains (76–85%). CONCLUSIONS: a) Rare enterovirus serotypes can cause serious illness. b) The molecular drift has also been shown for other enterovirus serotypes
Office Work and Complaints of the Arm, Neck and Shoulders: the Role of Job Characteristics, Muscular Tension and Need for Recovery
Objectives: This study investigated physical, psychological and social job
characteristics as potential risk factors for complaints of the arms, neck and shoulders (CANS) and mediating effects of muscular tension and need for recovery.
Methods: Data were collected among 105 computer workers using questionnaires and electromyography (EMG), and were analyzed with linear regression analyses. Results: Task interdependence, information processin
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