2,973 research outputs found

    Gauge dilution and leptogenesis

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    In this paper, we examine how gauge interactions can dilute the lepton asymmetry in lepton induced baryogenesis. Constraints imposed on Majorana masses keep this dilution at an acceptable level.Comment: 5 page

    Coupling of actin hydrolysis and polymerization: Reduced description with two nucleotide states

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    The polymerization of actin filaments is coupled to the hydrolysis of adenosine triphosphate (ATP), which involves both the cleavage of ATP and the release of inorganic phosphate. We describe hydrolysis by a reduced two-state model with a cooperative cleavage mechanism, where the cleavage rate depends on the state of the neighboring actin protomer in a filament. We obtain theoretical predictions of experimentally accessible steady state quantities such as the size of the ATP-actin cap, the size distribution of ATP-actin islands, and the cleavage flux for cooperative cleavage mechanisms.Comment: 6 page

    Molecular Diagnostics in the Mycosphaerella Leaf Spot Disease Complex of Banana and for Radopholus similis

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    Mycosphaerella leaf spots and nematodes threaten banana cultivation worldwide. The Mycosphaerella disease complex involves three related ascomycetous fungi: Mycosphaerella fijiensis, M. musicola and M. eumusae. The exact distribution of these three species and their disease epidemiology remain unclear, since their symptoms and life cycles are rather similar. Diagnosing these diseases and the respective causal agents is based on the presence of host symptoms and fungal fruiting structures, but is time consuming and not conducive to preventive management. In the present study, we developed rapid and robust species-specific diagnostic tools to detect and quantify M. fijiensis, M. musicola and M. eumusae. Conventional species-specific PCR primers were developed based on the actin gene that detected as little as 100, 1 and 10 pg/µl DNA from, respectively, M. fijiensis, M. musicola and M. eumusae. Furthermore, TaqMan real-time quantitative PCR assays that were developed based on the ß-tubulin gene detected quantities as low as 1 pg/µl DNA of each species from pure cultures and 1.6 pg/µl DNA/mg of M. fijiensis from dry leaf tissue. The efficacy of the tests was validated using naturally infected banana leaves. Similar technology has been used to develop a quantitative PCR assay for the banana burrowing nematode, Radopholus similis, which is currently being validate

    Discriminative Parameter Estimation for Random Walks Segmentation

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    The Random Walks (RW) algorithm is one of the most e - cient and easy-to-use probabilistic segmentation methods. By combining contrast terms with prior terms, it provides accurate segmentations of medical images in a fully automated manner. However, one of the main drawbacks of using the RW algorithm is that its parameters have to be hand-tuned. we propose a novel discriminative learning framework that estimates the parameters using a training dataset. The main challenge we face is that the training samples are not fully supervised. Speci cally, they provide a hard segmentation of the images, instead of a proba- bilistic segmentation. We overcome this challenge by treating the opti- mal probabilistic segmentation that is compatible with the given hard segmentation as a latent variable. This allows us to employ the latent support vector machine formulation for parameter estimation. We show that our approach signi cantly outperforms the baseline methods on a challenging dataset consisting of real clinical 3D MRI volumes of skeletal muscles.Comment: Medical Image Computing and Computer Assisted Interventaion (2013

    Non-local interactions in hydrodynamic turbulence at high Reynolds numbers: the slow emergence of scaling laws

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    We analyze the data stemming from a forced incompressible hydrodynamic simulation on a grid of 2048^3 regularly spaced points, with a Taylor Reynolds number of Re~1300. The forcing is given by the Taylor-Green flow, which shares similarities with the flow in several laboratory experiments, and the computation is run for ten turnover times in the turbulent steady state. At this Reynolds number the anisotropic large scale flow pattern, the inertial range, the bottleneck, and the dissipative range are clearly visible, thus providing a good test case for the study of turbulence as it appears in nature. Triadic interactions, the locality of energy fluxes, and structure functions of the velocity increments are computed. A comparison with runs at lower Reynolds numbers is performed, and shows the emergence of scaling laws for the relative amplitude of local and non-local interactions in spectral space. The scalings of the Kolmogorov constant, and of skewness and flatness of velocity increments, performed as well and are consistent with previous experimental results. Furthermore, the accumulation of energy in the small-scales associated with the bottleneck seems to occur on a span of wavenumbers that is independent of the Reynolds number, possibly ruling out an inertial range explanation for it. Finally, intermittency exponents seem to depart from standard models at high Re, leaving the interpretation of intermittency an open problem.Comment: 8 pages, 8 figure

    Tomographic Reconstruction from a Few Views: A Multi-Marginal Optimal Transport Approach

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    19 pagesInternational audienceIn this article, we focus on tomographic reconstruction. The problem is to determine the shape of the interior interface using a tomographic approach while very few X-ray radiographs are performed. We use a multi-marginal optimal transport approach. Preliminary numerical results are presented
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